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Stem cells : NPRStem cells
fuel cells : NPRfuel cells
Lock specific cells in ExcelAll cells have the Locked formatting by default, so this will protect all cells. ... All cells have the Locked formatting by default, so this will protect all cells. ... Type a password, and make sure that Protect worksheet and contents of locked cells is selected. ... Type a password, and make sure that Protect worksheet and contents of locked cells is selected. ...
STAP cells | Science NewsOngoing coverage of a controversial method for making stem cells ... Cells, STAP cells Stem cell papers retracted By Tina Hesman ... Contamination blamed in STAP stem cell debacle Investigation finds new form of flexible cells were really embryonic stem cells ... Science Ticker Cells, Science & Society, STAP cells Stem cell scientist reportedly agrees to retract controversial paper. ... Cells, STAP cells A little acid or a tight squeeze can turn a cell stemlike. ...
White Blood Cells - WikipediaWhite Blood Cells é dedicado a Loretta Lynn, cujo álbum Van Lear Rose (vencedor de dois prêmios Grammy e indicado a mais três) ... White Blood Cells é o terceiro álbum de estúdio da banda americana The White Stripes, lançado em 3 de julho de 2001 pela ... Performance de White Blood Cells nas paradas (allmusic) «2007 National Association of Recording Merchandisers». timepieces (em ...
Genes & Cells | Science NewsCells page features the latest news in genetics, cells, development, physiology, immune science, microbiology, epigenetics, ... Immune cells play surprising role in steady heartbeat Immune system cells called macrophages help heart cells rhythmically ... Cells' stunning complexity on display in a new online portal. A new online explorer tool from the Allen Institute for Cell ... Proteins that reprogram cells can turn back mice's aging clock. Proteins that reprogram adult cells to an embryonic-like state ...
fuel cells - Popular MechanicsGM Made This Wild Fuel Cell Van 50 Years Ago. GM's fuel cell development was powered by President John F. Kennedy's Project ... Toyota's Fuel Cell Big Rig Does 0-60 in 10 Seconds. This hydrogen-powered big rig makes 670 horses and 1325 lb-ft of torque, ... British company Intelligent Energy says it can fit such a cell into the iPhone 6. By Eric Limer ... The First Four-Seater Fuel Cell Plane Takes Flight. Emissions-free aviation. By Associated Press ...
Cell seeding - NanoSPACECell seeding posted Apr 7, 2015, 3:05 PM by Livia Visai If you have any comments, please feel free to send a massage to the ... The cells were removed from the flasks and seeded on particular type of slides, called thermanox. ...
Cell's Animated GifsCell's Animated ...
Stem Cells | Care2 Healthy LivingAfter Family Is Forced to Leave Animals in Car, Holiday Inn Grants Free Stays to Pets During ...
No data available that match "Cells"
(1/1036) E-CELL: software environment for whole-cell simulation.
MOTIVATION: Genome sequencing projects and further systematic functional analyses of complete gene sets are producing an unprecedented mass of molecular information for a wide range of model organisms. This provides us with a detailed account of the cell with which we may begin to build models for simulating intracellular molecular processes to predict the dynamic behavior of living cells. Previous work in biochemical and genetic simulation has isolated well-characterized pathways for detailed analysis, but methods for building integrative models of the cell that incorporate gene regulation, metabolism and signaling have not been established. We, therefore, were motivated to develop a software environment for building such integrative models based on gene sets, and running simulations to conduct experiments in silico. RESULTS: E-CELL, a modeling and simulation environment for biochemical and genetic processes, has been developed. The E-CELL system allows a user to define functions of proteins, protein-protein interactions, protein-DNA interactions, regulation of gene expression and other features of cellular metabolism, as a set of reaction rules. E-CELL simulates cell behavior by numerically integrating the differential equations described implicitly in these reaction rules. The user can observe, through a computer display, dynamic changes in concentrations of proteins, protein complexes and other chemical compounds in the cell. Using this software, we constructed a model of a hypothetical cell with only 127 genes sufficient for transcription, translation, energy production and phospholipid synthesis. Most of the genes are taken from Mycoplasma genitalium, the organism having the smallest known chromosome, whose complete 580 kb genome sequence was determined at TIGR in 1995. We discuss future applications of the E-CELL system with special respect to genome engineering. AVAILABILITY: The E-CELL software is available upon request. SUPPLEMENTARY INFORMATION: The complete list of rules of the developed cell model with kinetic parameters can be obtained via our web site at: http://e-cell.org/. (+info)
(2/1036) Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-gamma- and tumor necrosis factor (TNF)-alpha-dependent host resistance to the intracellular pathogen, Toxoplasma gondii.
Although interferon (IFN)-gamma-activated, mononuclear phagocytes are considered to be the major effectors of resistance to intracellular pathogens, it is unclear how they control the growth of microorganisms that reside in nonhemopoietic cells. Pathogens within such cells may be killed by metabolites secreted by activated macrophages or, alternatively, directly controlled by cytokine-induced microbicidal mechanisms triggered within infected nonphagocytic cells. To distinguish between these two basic mechanisms of cell-mediated immunity, reciprocal bone marrow chimeras were constructed between wild-type and IFN-gamma receptor-deficient mice and their survival assessed following infection with Toxoplasma gondii, a protozoan parasite that invades both hemopoietic and nonhemopoietic cell lineages. Resistance to acute and persistent infection was displayed only by animals in which IFN-gamma receptors were expressed in both cellular compartments. Parallel chimera experiments performed with tumor necrosis factor (TNF) receptor-deficient mice also indicated a codependence on hemopoietic and nonhemopoietic lineages for optimal control of the parasite. In contrast, in mice chimeric for inducible nitric oxide synthase (iNOS), an enzyme associated with IFN-gamma-induced macrophage microbicidal activity, expression by cells of hemopoietic origin was sufficient for host resistance. Together, these findings suggest that, in concert with bone marrow-derived effectors, nonhemopoietic cells can directly mediate, in the absence of endogenous iNOS, IFN-gamma- and TNF-alpha-dependent host resistance to intracellular infection. (+info)
(3/1036) Cellular microbiology: can we learn cell physiology from microorganisms?
Cellular microbiology is a new discipline that is emerging at the interface between cell biology and microbiology. The application of molecular techniques to the study of bacterial pathogenesis has made possible discoveries that are changing the way scientists view the bacterium-host interaction. Today, research on the molecular basis of the pathogenesis of infective diarrheal diseases of necessity transcends established boundaries between cell biology, bacteriology, intestinal pathophysiology, and immunology. The use of microbial pathogens to address questions in cell physiology is just now yielding promising applications and striking results. (+info)
(4/1036) Phase imaging by atomic force microscopy: analysis of living homoiothermic vertebrate cells.
Atomic force microscope-based phase imaging in air is capable of elucidating variations in material properties such as adhesion, friction, and viscoelasticity. However, the interpretation of phase images of specimens in a fluid environment requires clarification. In this report, we systematically analyzed atomic force microscope-derived phase images of mica, glass, and collagen under the same conditions as used for living cells at various tapping forces; the resulting data provide critical information for the interpretation of phase images of living cells. The peripheral regions of COS-1 cells consistently show a more negative phase shift than the glass substrate in phase images at set-point amplitude: free amplitude (Asp/A0) = 0.6-0.8. In addition, at all Asp/A0 values suitable for phase imaging, tapping frequency appears to be high enough to ensure that phase shifts are governed primarily by stiffness. Consequently, phase imaging is capable of high resolution studies of the cellular surface by detecting localized variations in stiffness. We demonstrate that phase imaging of a bifurcating fiber in COS-1 cell cytoplasm is readily capable of a lateral resolution of approximately 30 nm. (+info)
(5/1036) Single micro electrode dielectrophoretic tweezers for manipulation of suspended cells and particles.
Cells or particles in aqueous suspension close to a single capacitively coupled micro electrode (CCME) driven with high frequency electric fields experience dielectrophoretic forces. The effects near the CCME can be used for trapping and manipulation of single cells using externally metallised glass pipettes and might be used to develop a microscope based on force or capacitance measurements in conductive media. (+info)
(6/1036) Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type.
A multigenic family of Ca2+-binding proteins of the EF-hand type known as S100 comprises 19 members that are differentially expressed in a large number of cell types. Members of this protein family have been implicated in the Ca2+-dependent (and, in some cases, Zn2+- or Cu2+-dependent) regulation of a variety of intracellular activities such as protein phosphorylation, enzyme activities, cell proliferation (including neoplastic transformation) and differentiation, the dynamics of cytoskeleton constituents, the structural organization of membranes, intracellular Ca2+ homeostasis, inflammation, and in protection from oxidative cell damage. Some S100 members are released or secreted into the extracellular space and exert trophic or toxic effects depending on their concentration, act as chemoattractants for leukocytes, modulate cell proliferation, or regulate macrophage activation. Structural data suggest that many S100 members exist within cells as dimers in which the two monomers are related by a two-fold axis of rotation and that Ca2+ binding induces in individual monomers the exposure of a binding surface with which S100 dimers are believed to interact with their target proteins. Thus, any S100 dimer is suggested to expose two binding surfaces on opposite sides, which renders homodimeric S100 proteins ideal for crossbridging two homologous or heterologous target proteins. Although in some cases different S100 proteins share their target proteins, in most cases a high degree of target specificity has been described, suggesting that individual S100 members might be implicated in the regulation of specific activities. On the other hand, the relatively large number of target proteins identified for a single S100 protein might depend on the specific role played by the individual regions that in an S100 molecule contribute to the formation of the binding surface. The pleiotropic roles played by S100 members, the identification of S100 target proteins, the analysis of functional correlates of S100-target protein interactions, and the elucidation of the three-dimensional structure of some S100 members have greatly increased the interest in S100 proteins and our knowledge of S100 protein biology in the last few years. S100 proteins probably are an example of calcium-modulated, regulatory proteins that intervene in the fine tuning of a relatively large number of specific intracellular and (in the case of some members) extracellular activities. Systems, including knock-out animal models, should be now used with the aim of defining the correspondence between the in vitro regulatory role(s) attributed to individual members of this protein family and the in vivo function(s) of each S100 protein. (+info)
(7/1036) The osmotic migration of cells in a solute gradient.
The effect of a nonuniform solute concentration on the osmotic transport of water through the boundaries of a simple model cell is investigated. A system of two ordinary differential equations is derived for the motion of a single cell in the limit of a fast solute diffusion, and an analytic solution is obtained for one special case. A two-dimensional finite element model has been developed to simulate the more general case (finite diffusion rates, solute gradient induced by a solidification front). It is shown that the cell moves to regions of lower solute concentration due to the uneven flux of water through the cell boundaries. This mechanism has apparently not been discussed previously. The magnitude of this effect is small for red blood cells, the case in which all of the relevant parameters are known. We show, however, that it increases with cell size and membrane permeability, so this effect could be important for larger cells. The finite element model presented should also have other applications in the study of the response of cells to an osmotic stress and for the interaction of cells and solidification fronts. Such investigations are of major relevance for the optimization of cryopreservation processes. (+info)
(8/1036) A polarization model overcoming the geometric restrictions of the laplace solution for spheroidal cells: obtaining new equations for field-induced forces and transmembrane potential.
We present a new model for a variety of electric polarization effects on oblate and prolate homogeneous and single-shell spheroids. For homogeneous spheroids the model is identical to the Laplace model. For single-shell spheres of cell-like geometry the calculated difference of the induced dipole moments is in the thousandths range. To solve Laplace's equation for nonspherical single-shell objects it is necessary to assume a confocal shell, which results in different cell membrane properties in the pole and equator regions, respectively. Our alternative model addresses this drawback. It assumes that the disturbance of the external field due to polarization may project into the medium to a characteristic distance, the influential radius. This parameter is related to the axis ratio of the spheroid over the depolarizing factors and allows us to determine the geometry for a finite resistor-capacitor model. From this model the potential at the spheroid's surface is obtained and, consequently, the local field inside a homogeneous spheroid is determined. In the single-shell case, this is the effective local field of an equivalent homogeneous spheroid. Finally, integration over the volume yields the frequency-dependent induced dipole moment. The resistor-capacitor approach allowed us to find simple equations for the critical and characteristic frequencies, force plateaus and peak heights of deformation, dielectrophoresis and electrorotation for homogeneous and single-shell spheroids, and a more generalized equation for the induced transmembrane potential of spheroidal cells. (+info)
- Researchers who claimed to have grown a mouse fetus from stem cells made in acid baths were actually working with embryonic stem cells, an investigation finds. (sciencenews.org)
- The discredited stem cells known as STAP cells were ultraflexible because they were really embryonic stem cells, a new report contends. (sciencenews.org)
- On December 26, RIKEN issued a report saying that what the researchers claimed were STAP cells were really embryonic stem cells contaminating the lab dishes. (sciencenews.org)
- They used a common cold virus to carry transformative genes into ordinary mouse cells and made them look and act like embryonic stem cells. (redorbit.com)
- Doctors consider embryonic stem cells the most powerful kinds of stem cells, because they can give rise to any type of tissue. (redorbit.com)
- These cells look and act like embryonic stem cells. (redorbit.com)
- A breakthrough in stem cell research has been achieved with scientists using cloning techniques to turn human skin cells into embryonic stem cells. (abc.net.au)
- Last January, researchers claimed in two papers published in Nature that they had made stem cells by briefly dipping adult cells in a dilute acid bath or by giving the cells a squeeze ( SN: 2/22/14, p. 6 ). (sciencenews.org)
- He said, as the cells divide, they dilute the virus until it disappears but the genetic changes remain. (redorbit.com)
- They injected these cells into mouse embryos and when the pups were born, they showed evidence that the cells had indeed transformed them. (redorbit.com)
- Embryo debate The imminent creation of embryos from stem cells for research will raise ethical issues that need to be debated now, say scientists. (abc.net.au)
stem cell science
- The report may close the book on a year-long saga that has marred stem cell science ( SN: 12/27/14, p. 25 ). (sciencenews.org)
- Dr Karl dissects the controversial world of stem cell science. (abc.net.au)
- Great Moments in Science Do you know the difference between an embryonic stem cell and an adult stem cell? (abc.net.au)
- Abnormal groupings of germ cells that cluster together, becoming tumors, tend to develop in the ovaries or testes. (kidshealth.org)
- Sometimes, though, because germ cells can settle in other places along their way to the reproductive organs, tumors can form in other areas. (kidshealth.org)
- The most common sites for germ cell tumors outside of the reproductive tract are the mediastinum (part of the chest between the breastplate and spine), tailbone, abdomen, and pelvis. (kidshealth.org)
- Like tumors that occur in other places in the body, germ cell tumors can be benign (not cancerous) or malignant (cancerous). (kidshealth.org)
- The cause of most germ cell tumors is not well known. (kidshealth.org)
- Children with benign germ cell tumors will undergo surgery to remove the tumor. (kidshealth.org)
- Researchers claim they developed a safer way to make powerful stem cells from ordinary skin cells, improving research focused on so-called regenerative medicine. (redorbit.com)
- British and Japanese scientists have managed to reset human stem cells to their earliest state, opening up a new realm of research into the start of human development and potentially life-saving regenerative medicines. (abc.net.au)
- White Blood Cells é o terceiro álbum de estúdio da banda americana The White Stripes, lançado em 3 de julho de 2001 pela gravadora independente Sympathy for the Record Industry, e mais tarde relançado pela V2 Recordings em 2002. (wikipedia.org)
- White Blood Cells é dedicado a Loretta Lynn, cujo álbum Van Lear Rose (vencedor de dois prêmios Grammy e indicado a mais três) seria produzido por Jack White em 2004. (wikipedia.org)
- Leukemia is a cancer that affects white blood cells (leukocytes). (slideshare.net)
- White blood cells are made by adult stem cells and are released into the blood stream to fight infections. (slideshare.net)
- When you have leukemia your white blood cells don't grow nor function correctly. (slideshare.net)
- Germ cells are the cells in a developing fetus that eventually produce sperm in males and eggs in females. (kidshealth.org)
- These cells normally develop along what's called the "midline" of a fetus (usually where the stomach and other internal organs will lie) before finally settling into place in the reproductive organs. (kidshealth.org)
- She grows artificial hearts and bones using new techniques she developed to care for artificially grown cells. (american.edu)
- Australian researchers have grown a rudimentary kidney in the laboratory from human stem cells, an advance they say could lead to better ways of treating renal disease and testing drug safety. (abc.net.au)
- Scientists have grown human liver tissue from stem cells in a first that holds promise for alleviating the critical shortage of donor organs. (abc.net.au)
- Researchers who reported an easy method for making stem cells admit mistakes mar their work, and have retracted their papers from Nature. (sciencenews.org)
- Researchers used both mouse skin cells and liver cells from fetal mice and made types to look and act like iPS cells. (redorbit.com)
- Researchers have been able to grow new bone using a monkey's own skin cells. (abc.net.au)
- In her presentation " Super Cells: Building with Biology ," Tandon will describe the inventions being created with cells. (american.edu)
- STEM CELLS AND DEVELOPMENT is particularly committed to providing authors comprehensive yet rapid evaluation of original reports describing developments in hematopoietic progenitor cell processing, purging, identification, expansion, biochemistry, molecular biology, and engraftment. (liebertpub.com)
- Japanese stem cell scientist Haruko Obokata has agreed to retract one of the Jan. 30 Nature papers on STAP cells. (sciencenews.org)
- Johns Hopkins scientist Charles Eberhart discusses recent research on blocking pathways that contribute to brain cancer stem cell growth. (redorbit.com)
- STEM CELLS AND DEVELOPMENT welcomes papers covering widely diverse aspects of hematology, bone marrow transplantation, immune reconstitution, and progenitor cell biochemistry and characterization. (liebertpub.com)
- Doctors believe some day, they may be able to make tailor-made transplants to treat diseases in people by removing a few cells, transforming them in the lab and transplanting the new tissue or organs back in. (redorbit.com)
- Also to make sure every last affected cell is killed, doctors will put an additional drug in their blood stream to get the few cells chemo or radiation might have missed. (slideshare.net)
- Doctors do know that certain medical conditions can make a child more likely to develop a germ cell tumor. (kidshealth.org)
- It results in this stripy pattern of brown fur that comes from the iPS cells and black fur which comes from the host embryo tissue," Hochedlinger said. (redorbit.com)
- She also works as an electrical and biomedical engineer at Columbia University's Laboratory for Stem Cells and Tissue Engineering. (american.edu)
- Scientists have used stem cells to build the world's first 'mini-stomachs' - tiny clusters of human gastric tissue - that could foster research into cancer, ulcers and diabetes. (abc.net.au)
- Your submission to Stem Cells and Development provides you with robust tools and support to ensure maximum impact and readership for your work. (liebertpub.com)
- Stem Cells and Development carries a manuscript processing charge* of $75 USD upon submission of each new manuscript. (liebertpub.com)
- GM's fuel cell development was powered by President John F. Kennedy's Project Gemini and the Apollo Program. (popularmechanics.com)
- Adult stem cells (ASC) are undifferentiated cells that are in the body after development. (slideshare.net)
- Submitting your manuscript to Stem Cells and Development delivers a comprehensive benefits program that ensures high-quality review of your research and maximum impact for your work. (liebertpub.com)
- To test the cells, scientists made chimeras --- a blend of two separate animals. (redorbit.com)
- Customised neurones Scientists in Australia have used a 3D printer to create nerve cells found in the brain using a special bio-ink made from stem cells. (abc.net.au)
- Safer Stem Cells Research? (redorbit.com)
- What's Nobel about stem cell research? (abc.net.au)
- Great Moments in Science Two scientists were recently awarded Nobel Prizes for their research on adult stem cells. (abc.net.au)
- If it can be replicated with human cells, it may offer a safe way to test cell therapy to treat diseases such as sickle cell anemia or Parkinson's, Konrad Hochedlinger of Massachusetts General Hospital and Harvard Medical School in Boston reported in the journal Science. (redorbit.com)
- During the past few months, several teams of scientists say they have found a handful of genes that can transform ordinary skin cells into induced pluripotent stem cells, or iPS cells. (redorbit.com)
- Scientists used retroviruses to turn genes into cells. (redorbit.com)
- 3. The Two Main Properties Of ASC Self-renewal-the ability to go through the cycle of cell division many times while still keeping its undifferentiated state Multipotency (Multidifferentiative Potential)-the ability to make offspring of many different cell types. (slideshare.net)
- each is classified according to the specific types of germ cells present and their location in the body. (kidshealth.org)
- The cells making up this malignant tumor usually develop among other types of malignant cells. (kidshealth.org)
- Type a password, and make sure that Protect worksheet and contents of locked cells is selected. (microsoft.com)
- Experts say stem cells are the body's master cells that give rise to all the tissues, like organs and blood. (redorbit.com)
- The definitive rapid-publication journal covering all aspects of gene therapy through original investigations into the transfer and expression of genes in mammals, with in-depth coverage of DNA, RNA, and cell therapies. (liebertpub.com)
- We are in the process already of trying to make integration-free iPS cells in human cells," Hochedlinger said. (redorbit.com)
- This interesting mix of perspectives also taught me that the cells that form the very fabric of our being also mediate our experience of life. (american.edu)
- After months of failing to replicate her work, Obokata resigned and RIKEN said it would cease efforts to re-create the cells. (sciencenews.org)
- 18. Step 4: "Cleaning The Infected Patient" Before the patient receives the unaffected blood he/she goes through en enduring dose of radiation or chemotherapy to clear their body of any affected cells. (slideshare.net)
- I understood that these cells, which might compose our eyes and also interpret the neural signals they produce, like any living object, are both miraculous and fallible. (american.edu)
- Next, the donor must be administered anesthesia while the healthy blood cells are collected. (slideshare.net)