Bleeding within the subcortical regions of cerebral hemispheres (BASAL GANGLIA). It is often associated with HYPERTENSION or ARTERIOVENOUS MALFORMATIONS. Clinical manifestations may include HEADACHE; DYSKINESIAS; and HEMIPARESIS.
Large subcortical nuclear masses derived from the telencephalon and located in the basal regions of the cerebral hemispheres.

Evidence for apoptosis after intercerebral hemorrhage in rat striatum. (1/26)

The overall hypothesis that cell death after intracerebral hemorrhage is mediated in part by apoptotic mechanisms was tested. Intracerebral hemorrhage was induced in rats using stereotactic infusions of 0.5 U of collagenase (1-microL volume) into the striatum. After 24 hours, large numbers of TUNEL-positive stained cells with morphologies suggestive of apoptosis were present in the center and periphery of the hemorrhage. Double staining with Nissl and immunocytochemical labeling with antibodies against neuronal nuclei and glial fibrillary acidic protein suggested that these TUNEL-positive cells were mostly neurons and astrocytes. Electrophoresis of hemorrhagic brain extracts showed evidence of DNA laddering into approximately 200-bp fragments. Western blots showed cleavage of the cytosolic caspase substrate gelsolin. The density of TUNEL-positive cells at 24 and 48 hours after hemorrhage was significantly reduced by treatment with the broad-spectrum caspase inhibitor zVADfmk. It was unlikely that apoptotic changes were due to neurotoxicity of injected collagenase because TUNEL-positive cells and DNA laddering were also obtained in an alternative model of hemorrhage where autologous blood was infused into the striatum. Furthermore, equivalent doses of collagenase did not induce cell death in primary neuronal cultures. These results provide initial evidence that apoptotic mechanisms may mediate some of the injury in brain after intracerebral hemorrhage.  (+info)

Striatocapsular haemorrhage. (2/26)

Haemorrhages in the striatocapsular area, or striatocapsular haemorrhages (SCHs), have been regarded as a single entity, although the area is composed of several functionally discrete structures that receive blood supply from different arteries. We analysed the morphological and clinical presentations of 215 cases of SCHs according to a new classification method we have designed on the basis of arterial territories. SCHs were divided into six types: (i) anterior type (Heubner's artery); (ii) middle type (medial lenticulostriate artery); (iii) posteromedial type (anterior choroidal artery); (iv) posterolateral type (posteromedial branches of lateral lenticulostriate artery); (v) lateral type (most lateral branches of lateral lenticulostriate artery); and (vi) massive type. The anterior type (11%) formed small caudate haematomas, always ruptured into the lateral ventricle, causing severe headache, and mild contralateral hemiparesis developed occasionally. The outcome was excellent. The middle type (7%) involved the globus pallidus and medial putamen, frequently causing contralateral hemiparesis and transient conjugate eye deviation to the lesion side. About 50% of the patients recovered to normal. The posteromedial type (4%) formed very small haematomas in the posterior limb of the internal capsule and presented with mild dysarthria, contralateral hemiparesis and sensory deficit, with excellent outcome in general. The posterolateral type (33%) affected the posterior half of the putamen and posterior limb of the internal capsule and presented with impaired consciousness and contralateral hemiparesis with either language dysfunction or contralateral neglect. The outcome was fair to poor but there were no deaths. The lateral type (21%) formed large elliptical haematomas between the putamen and insular cortex. Contralateral hemiparesis with language dysfunction or contralateral neglect developed frequently but resolved over several weeks. The clinical outcome was relatively excellent except when the haematoma size was very large. The massive type (24%) formed huge haematomas affecting the entire striatocapsular area. Marked sensorimotor deficits and impaired consciousness, ocular movement dysfunctions including the 'wrong-way' eyes were observed quite frequently. The outcome was very poor with a case fatality rate of 81%. The clinico-radiological presentations suggested its origin was the same as the posterolateral type.  (+info)

Relationship between stroke and asymptomatic minute hemorrhages in hypertensive patients. (3/26)

Asymptomatic small hemorrhages were identified in hypertensive patients by T2*-weighted gradient echo magnetic resonance (MR) imaging to investigate the relationship between hypertensive intracerebral hemorrhage and asymptomatic minute hemorrhages. Forty-eight patients with hypertensive intracerebral hemorrhage or cerebral infarction with hypertension (these diseases were defined as stroke) were treated in National Defense Medical College from April 1998 to February 2000. All patients had no past history of stroke or head injury, underwent MR imaging within 6 months of the stroke attack, were aged from 40 to 80 years, and had no diagnosis of aneurysm, angioma, or moyamoya disease. Patients were divided into the infarction group and hemorrhage group. All foci over 2 mm in size appearing as hypointense on T2*-weighted MR imaging and unrelated to stroke areas were defined as minute hemorrhages. There were no significant differences between the two groups with respect to sex, age, and history of diabetes mellitus. The incidence of minute hemorrhages in the hemorrhage group (21/26) was greater than in the infarction group (9/22, p < 0.01). The incidence of minute hemorrhages in the basal ganglia (18/26) was greater in the hemorrhage group than in the infarction group (4/22, p < 0.001). Symptomatic intracerebral hemorrhage may be preceded by asymptomatic minute hemorrhage.  (+info)

Hypertensive caudate hemorrhage prognostic predictor, outcome, and role of external ventricular drainage. (4/26)

BACKGROUND AND PURPOSE: The purpose of the present study was to analyze the outcome and outcome predictors of caudate hemorrhage and role of external ventricular drainage in acute hydrocephalus. METHODS: Clinical data from 36 consecutive patients with hypertensive caudate hemorrhage was used in the present study. Age, gender, volume of parenchymal hematoma, hematoma in the internal capsule, initial Glasgow Coma Scale (GCS), hydrocephalus, severity of intraventricular hemorrhage, and hemorrhagic dilatation of the fourth ventricle were analyzed for effect on outcome. Effect of external ventricle drainage for hydrocephalus was evaluated by comparing preoperative and postoperative GCS scores. RESULTS: By univariate analyses, poor outcome was associated with a poor initial GCS score (P=0.016), hydrocephalus (P<0.001), intraventricular hemorrhage severity (P<0.01), and hemorrhagic dilatation of the fourth ventricle (P=0.02). By multivariate analysis, stepwise logistic regression revealed that hydrocephalus was the only independent prognostic factor for poor outcome (P<0.001). Postoperative 48-hour GCS score was better than the preoperative score by use of paired-sample t test (P<0.001). CONCLUSIONS: Hydrocephalus is the most important predictor of poor outcome. External ventricular drainage response for hydrocephalus was good in the present study, whereas an early decision should be made regarding preoperative neurological condition.  (+info)

Longitudinal changes of metabolites in frontal lobes after hemorrhagic stroke of basal ganglia: a proton magnetic resonance spectroscopy study. (5/26)

BACKGROUND AND PURPOSE: We investigated serial metabolic changes in frontal lobes of patients with deep intracerebral hemorrhage (ICH) to examine the correlation between N-acetylaspartate (NAA) and degree of motor impairment or clinical outcome. METHODS: - Twenty patients with deep ICH were examined with proton magnetic resonance spectroscopy with the application of a multivoxel method (1 voxel=10x10x20 mm; 64 voxels). NAA/creatine ratios in the white matter of the primary motor and premotor areas on both sides were measured sequentially: within 48 hours, at 2 weeks, and 1 month after onset. The National Institutes of Health Stroke Scale and Barthel Index for disability were measured for each patient. RESULTS: - In the primary motor area on the affected side, where the hematoma did not extend, the NAA/creatine ratio decreased sequentially. At 48 hours and 2 weeks after onset, a negative correlation was detected between NAA/creatine and hematoma volume, but there was no correlation 1 month later. At 2 weeks, NAA/creatine correlated negatively with motor impairment (r=-0.750), and there was a significant correlation with clinical outcome as early as 2 weeks after onset (r=0.954). These sequential changes of NAA/creatine varied according to patients' long-term clinical outcome. Patients with poor outcome demonstrated notable reduction of NAA/creatine over the bilateral frontal lobes. CONCLUSIONS: - The delayed gradual reduction of NAA/creatine ratio in the frontal lobes correlates with motor deficit and clinical outcome after deep ICH, suggesting that the neural networks in the frontal lobe could be important for recovery.  (+info)

Stereotactic fibrinolysis of spontaneous intracerebral hematoma using infusion of recombinant tissue plasminogen activator. (6/26)

PURPOSE: The authors present a prospective study on 10 patients with stereotactic infusion of tissue plasminogen activator (rtPA) intraparenchimal hemorrhage. METHODS: Between 1999 and 2000, 10 patients with deep seated hematomas in the basal ganglia were selected for stereotactic infusion of rtPA and spontaneous clot drainage. RESULTS: All cases had about 80% reduction of the hematoma volume in the CT scan at the third day. The intracranial pressure was normalized by the third day too. There were no local or systemic complications with the use of this thrombolytic. The results were shown by the Glasgow Outcome Scale with six patients in V, three in IV and one in III after 3 months. CONCLUSION: Early treatment and drainage with minimally invasive neurosurgery, can make these patients with deep-seated hematomas recover the consciousness and they can be rehabilitated earlier avoiding secondary complications.  (+info)

Possible acute hemorrhagic leukoencephalitis manifesting as intracerebral hemorrhage on computed tomography--case report. (7/26)

A 15-year-old girl presented with meningeal irritation and bilateral cerebral signs after contracting influenza. A lumbar puncture revealed bloody cerebrospinal fluid and polymorphonuclear predominant pleocytosis with an elevated protein level and normal glucose level. Computed tomography showed a hematoma in the right basal ganglia and lateral ventricles. Symmetrical low density areas were also noted in the bilateral white matter. The preliminary diagnosis was hemorrhagic cerebrovascular disease of unknown cause. However, her neurological condition deteriorated. Magnetic resonance (MR) imaging showed diffuse high intensity signals in the bilateral white matter and small spotty lesions, indicating hemorrhages in various stages. The final diagnosis was acute hemorrhagic leukoencephalitis (AHL). However, high-dose steroid administration and plasmapheresis failed to improve her condition. Hypothermia could not control her intracranial pressure and she died 12 days after admission. The neuroimaging findings indicated the histological characteristics of AHL, but the hematoma formation is rare. AHL is a fulminant form of brain demyelination and can be fatal, so early diagnosis and aggressive treatment are important for successful recovery. Therefore, early investigation by MR imaging is necessary.  (+info)

Interobserver agreement in the assessment of lobar versus deep location of intracerebral haematomas on CT. (8/26)

In patients with supratentorial intracerebral haemorrhage (ICH), it is important to discriminate superficial (lobar) and deep (basal ganglia) location, since this has consequences for research and prognosis. Haemorrhages at these sites have different causes and different risk factors. We studied the interobserver variation between three radiologists in classifying fifty large haematomas on CT as deep or lobar. The kappa values were almost perfect, ranging from 0.88 to 0.96. We conclude that the assessment of CT by radiologist is a reliable method to discriminate between lobar versus deep origin even for large intracerebral haematomas.  (+info)

A basal ganglia hemorrhage is a type of intracranial hemorrhage, which is defined as bleeding within the skull or brain. Specifically, a basal ganglia hemorrhage involves bleeding into the basal ganglia, which are clusters of neurons located deep within the forebrain and are involved in regulating movement, cognition, and emotion.

Basal ganglia hemorrhages can result from various factors, including hypertension (high blood pressure), cerebral amyloid angiopathy, illicit drug use (such as cocaine or amphetamines), and head trauma. Symptoms of a basal ganglia hemorrhage may include sudden onset of severe headache, altered consciousness, weakness or paralysis on one side of the body, difficulty speaking or understanding speech, and visual disturbances.

Diagnosis of a basal ganglia hemorrhage typically involves imaging studies such as computed tomography (CT) or magnetic resonance imaging (MRI). Treatment may include supportive care, medications to control symptoms, and surgical intervention in some cases. The prognosis for individuals with a basal ganglia hemorrhage varies depending on the severity of the bleed, the presence of underlying medical conditions, and the timeliness and effectiveness of treatment.

The basal ganglia are a group of interconnected nuclei, or clusters of neurons, located in the base of the brain. They play a crucial role in regulating motor function, cognition, and emotion. The main components of the basal ganglia include the striatum (made up of the caudate nucleus, putamen, and ventral striatum), globus pallidus (divided into external and internal segments), subthalamic nucleus, and substantia nigra (with its pars compacta and pars reticulata).

The basal ganglia receive input from various regions of the cerebral cortex and other brain areas. They process this information and send output back to the thalamus and cortex, helping to modulate and coordinate movement. The basal ganglia also contribute to higher cognitive functions such as learning, decision-making, and habit formation. Dysfunction in the basal ganglia can lead to neurological disorders like Parkinson's disease, Huntington's disease, and dystonia.

Such hemorrhages are typically located in the basal ganglia, cerebellum, or occipital lobes. Other location such as bleed ... It can cause epidural hemorrhage, subdural hemorrhage, and subarachnoid hemorrhage. Other condition such as hemorrhagic ... Basal ganglia, posterior fossa, and brainstem are spared. Boston criteria is used to determine the likelihood of a cerebral ... Types of intracranial hemorrhage are roughly grouped into intra-axial and extra-axial. Intra-axial hemorrhage is bleeding ...
These include the basal ganglia, language cortices, sensorimotor regions, and white matter tracts. Importantly, eloquent areas ... intraventricular hemorrhage). Cerebral hemorrhage appears to be most common. One long-term study (mean follow up greater than ... The earlier an AVM appears, the more likely it is to cause hemorrhage over one's lifetime; e.g. (assuming a 3% annual risk), an ... Based on this system, AVMs may be classified as grades 1-5. This system was not intended to characterize risk of hemorrhage. " ...
... basal ganglia, the pons, the oblongate and from the cerebellum. Cufflike pattern hemorrhages around small brain vessels were ... These hemorrhages are caused by sudden changes of the intravascular blood pressure as a result of a compression of ... Proponents of the concept point to human autopsy results demonstrating brain hemorrhaging from fatal hits to the chest, ... Summary, Příčiny vzniku perikapilárních hemoragií v mozku při střelných poraněních (Causes of pericapillar brain haemorrhages ...
Hemorrhage into the basal ganglia or thalamus causes contralateral hemiplegia due to damage to the internal capsule. Other ... Aspiration by stereotactic surgery or endoscopic drainage may be used in basal ganglia hemorrhages, although successful reports ... "Brain Bleed/Hemorrhage (Intracranial Hemorrhage): Causes, Symptoms, Treatment". Naidich TP, Castillo M, Cha S, Smirniotopoulos ... This kind of hemorrhage can also occur in the cortex or subcortical areas, usually in the frontal or temporal lobes when due to ...
It involves placing a tiny electrical probe in the globus pallidus, one of the basal ganglia of the brain, to damage it. ... Damage to a blood vessel may cause intracranial haemorrhage. Damage to the optic tract can cause a permanent vision problem. ... The internal globus pallidus can be regarded as an "output structure" of the basal ganglia. It processes input from nucleus ... It is critical for the functioning of the basal ganglia. Pallidotomy is an alternative to deep brain stimulation for the ...
... s are most often located in the lenticulostriate vessels of the basal ganglia and are associated with ... Intracranial hemorrhage Fausto, [ed. by] Vinay Kumar; Abul K. Abbas; Nelson (2005). Robbins and Cotran Pathologic Basis of ... Charcot-Bouchard aneurysms are a common cause of cerebral hemorrhage. Retinal microaneurysms are seen in conditions like ... Common locations of hypertensive hemorrhages include the putamen, caudate, thalamus, pons, and cerebellum.[citation needed] As ...
... rather than deep white matter or basal ganglia. These are usually described as "lobar". These bleedings are not associated with ... This hemorrhage rarely extends into the ventricular system. Nontraumatic intraparenchymal hemorrhage most commonly results from ... Clinical manifestations of intraparenchymal hemorrhage are determined by the size and location of hemorrhage, but may include ... The other form is intraventricular hemorrhage (IVH). Intraparenchymal hemorrhage accounts for approximately 8-13% of all ...
... with intracranial haemorrhage due to high blood pressure which occurs in deep locations of the brain such as basal ganglia and ... The Boston Criteria require evidence of multiple lobar or cortical hemorrhages to label a patient as probably having CAA. ... In 1979, H. Okazaki published a paper implicating CAA in certain cases of lobar intracerebral hemorrhage. The Boston Criteria ... CAA is associated with brain hemorrhages, particularly microhemorrhages. Since CAA can be caused by the same amyloid protein ...
... basal ganglia cerebrovascular disease MeSH C10.228.140.079.127.500 - basal ganglia hemorrhage MeSH C10.228.140.079.127.500.500 ... basal ganglia cerebrovascular disease MeSH C10.228.140.300.100.200 - basal ganglia hemorrhage MeSH C10.228.140.300.100.200.500 ... intracranial hemorrhages MeSH C10.228.140.300.535.200 - cerebral hemorrhage MeSH C10.228.140.300.535.200.150 - basal ganglia ... hemorrhage MeSH C10.228.140.300.535.200.150.500 - putaminal hemorrhage MeSH C10.228.140.300.535.200.200 - cerebral hemorrhage, ...
Injuries to the frontal lobe and/or the basal ganglia can interfere with an individual's ability to initiate speech, movement, ... or intracerebral hemorrhage (stroke), especially stroke causing diffuse injury to the right hemisphere. ... of patients with lesions on their basal ganglia experience some form of diminished motivation. It may complicate rehabilitation ... frontal circuits through which the flow of information from the entire cortex takes place before reaching the basal ganglia. ...
... basal ganglia, thalamus and areas near the third ventricle. The hemorrhages can occur as the result of brain herniation, which ... Hemorrhages may be larger than in normal contusions if the injury is quite severe. This type of injury has a poor prognosis if ... A type of diffuse brain injury, multiple petechial hemorrhages are not always visible using current imaging techniques like CT ... The distinction between contusion and intracerebral hemorrhage is blurry because both involve bleeding within the brain tissue ...
... rarity of isolated infarct or hemorrhage within the putamen, etc.). However, many studies have been done on the basal ganglia ... The basal ganglia are located bilaterally, and have rostral and caudal divisions. The putamen is located in the rostral ... The basal ganglia receive input from the cerebral cortex, via the striatum. The putamen is interconnected with the following ... Seven participants with basal ganglia lesions were used in the experiment, along with nine control participants. It is ...
... most often the lenticulostriate vessels of the basal ganglia, and are associated with chronic hypertension. Charcot-Bouchard ... This leads to hemorrhage in the subarachnoid space and sometimes in brain parenchyma. Minor leakage from aneurysm may precede ... Generally patients with Hunt and Hess grade I and II hemorrhage on admission to the emergency room and patients who are younger ... Symptoms of a subarachnoid hemorrhage differ depending on the site and size of the aneurysm. Symptoms of a ruptured aneurysm ...
... basal ganglia cerebrovascular disease MeSH C14.907.253.061.200 - basal ganglia hemorrhage MeSH C14.907.253.061.200.500 - ... cerebral hemorrhage MeSH C14.907.253.420.150 - basal ganglia hemorrhage MeSH C14.907.253.420.150.500 - putaminal hemorrhage ... intracranial hemorrhages MeSH C14.907.253.573.200 - cerebral hemorrhage MeSH C14.907.253.573.200.150 - basal ganglia hemorrhage ... brain hemorrhage, traumatic MeSH C14.907.253.573.400.150.200 - brain stem hemorrhage, traumatic MeSH C14.907.253.573.400.150. ...
... intracranial hemorrhages MeSH C23.550.414.913.100 - cerebral hemorrhage MeSH C23.550.414.913.100.200 - basal ganglia hemorrhage ... subarachnoid hemorrhage MeSH C23.550.414.922 - oral hemorrhage MeSH C23.550.414.922.500 - gingival hemorrhage MeSH C23.550. ... retinal hemorrhage MeSH C23.550.414.756.887 - vitreous hemorrhage MeSH C23.550.414.788 - gastrointestinal hemorrhage MeSH ... eye hemorrhage MeSH C23.550.414.756.300 - choroid hemorrhage MeSH C23.550.414.756.550 - hyphema MeSH C23.550.414.756.775 - ...
Bilateral necrosis of basal ganglia, mostly of the putamen, with or without haemorrhage, and haemorrhagic lesions in the ... Methanol poisoning is associated with executive dysfunction and explicit memory impairment, due to basal ganglia dysfunction ... cerebral and intraventricular haemorrhage, optic haemorrhages, nerve lesions, and convulsions that may occur after edema of the ... Because of their high energy dependency, retinal ganglion cells and their axons, which compose the optic nerve, are ...
TMA is caused by lesions in cortical motor areas of the brain as well as lesions in the anterior portion of the basal ganglia, ... and is usually due to minor hemorrhage or contusion in the temporal lobe, or infarcts of the left posterior cerebral artery ( ...
... and basal ganglia, and cause cell death and tissue degeneration. Blood clots also accelerate arterioscelerosis, which causes ... A lacunar infarction occurs when an artery is blocked and an intracerebral hemorrhage occurs when the blood vessels burst. In ... Vascular dementia is characterized by ischemic infarcts, cerebral hemorrhages, white matter lesions, BBB dysfunction, and/or ... Hypertension→ Small vessel disease → Lacunar infarction & Intracerebral hemorrhage → Tissue damage Vascular dementia develops ...
... or hemiballism is a basal ganglia syndrome resulting from damage to the subthalamic nucleus in the basal ganglia ... it has been suggested that petechial hemorrhage or a decreased production of GABA and acetylcholine could result secondary to ... In the basal ganglia, this can result in the death of tissue that helps to control movement. As a result, the brain is left ... The basal ganglia are a collection of nuclei that connects to several other areas of the brain. Due to the diverse nuclei that ...
Several studies proposed an association with specific lesions (left anterior and basal ganglia lesions and lesions close to ... "Mouse models of intracerebral hemorrhage in ventricle, cortex, and hippocampus by injections of autologous blood or collagenase ... Some studies reported an association between post-stroke mania and right orbital frontal, basotemporal, basal ganglia lesions. ... These norepinephrinergic and serotoninergic pathways are disrupted in basal ganglia and frontal lobe lesions - sites that are ...
... thalami and basal ganglia may also be involved. When a person has more than one demyelinating episode of ADEM, the disease is ... The high incidence of ADEM with hemorrhage is striking. Brain inflammation is likely caused by an immune response to the ... basal ganglia, cerebellum, and brainstem suggests an acute demyelination process. Additionally, hemorrhagic white matter ... and is characterized by necrotizing vasculitis of venules and hemorrhage, and edema. Death is common in the first week and ...
Patients with pure basal ganglia and thalamus lesions are more likely to show more severe choreoathetosis whereas dystonia may ... Other aetiological factors are growth retardation, brain maldevelopment, intracranial haemorrhage, stroke or cerebral ... more specifically in the basal ganglia and thalamus. However, other brain lesions and even normal-appearing MRI findings can ...
However, those who have deep cerebral venous sinus thrombosis or oedema at basal ganglia are more prone to hydrocephalus ... If the hemorrhage has decreased in size, anticoagulants are started, while no anticoagulants are given if there is no reduction ... Before these trials had been conducted, there had been a concern that small areas of hemorrhage in the brain would bleed ... Some experts discourage the use of anticoagulation if there is extensive hemorrhage; in that case, they recommend repeating the ...
The accumulation of mutated proteins results in brain damage of the basal ganglia. Developing babies can have birth defects ... A stroke may result from a blood clot or hemorrhage. A neurodegenerative disease is a disease that causes damage to neurons. ...
... stem cells into the basal ganglia or stimulating endogenous stem cell production and movement to the basal ganglia. The ... and cerebral hemorrhage are possible, causing many physicians to believe the risks outweigh the possible benefits. Another ... In the basal ganglia, the nigrostriatal pathway is where GABA and dopamine are housed in the same neurons and released together ... The basal ganglia have been tied to the incentives behind movement, therefore suggesting a cost/benefit analysis of planned ...
... matter hyperintensities occur adjacent to the lateral ventricles and subcortical hyperintensities occur in the basal ganglia.[ ... White matter hyperintensities can be caused by a variety of factors including ischemia, micro-hemorrhages, gliosis, damage to ...
... basal ganglia, thalami, brainstem and pons. These distinct patterns do not generally correlate with the nature of the symptoms ... In 10-25% of cases of PRES there is evidence of hemorrhage on neuroimaging. Various types of hemorrhage may occur: hemorrhage ... PRES may be complicated by intracranial hemorrhage, but this is relatively rare. The majority of people recover fully, although ... Of those who have residual symptoms after PRES, this is attributable largely to hemorrhage. Non-resolution of MRI abnormalities ...
... basal ganglia, amygdala, brain stem, internal capsule, corpus callosum, and cerebellum. Brain volume reduction seems to be ... Brain injury is common among preterms, ranging from white matter injury to intraventricular and cerebellar haemorrhages. The ... and intraventricular hemorrhage, the latter affecting 25% of babies born preterm, usually before 32 weeks of pregnancy. Mild ... intraventricular and cerebellar hemorrhage". Clinics in Perinatology. 41 (1): 69-82. doi:10.1016/j.clp.2013.09.005. PMID ...
A neurocognitive model - the notion that the basal ganglia play a role in habit formation and that the frontal lobes are ... A biopsy can be performed and may be helpful; it reveals traumatized hair follicles with perifollicular hemorrhage, fragmented ... An fMRI study reported decreased activation in the basal ganglia, dorsolateral prefrontal cortex, and dorsal anterior cingulate ...
Treatment was based on the theory that there is an imbalance of the neurotransmitter dopamine in the basal ganglia. These drugs ... intracerebral hemorrhage (0.6%), intraventricular hemorrhage (0.6%), and large subdural hematoma (0.3%). Physical treatment ... Deep brain stimulation to the basal ganglia and thalamus has recently been used as a successful treatment for tremors of ... Although no lesions are present in the basal ganglia in primary spasmodic torticollis, fMRI and PET studies have shown ...
Source images of the perfusion-weighted imaging show the bolus of gadolinium (dark) passing through the vasculature. Dark gadolinium is seen leaking from the vasculature and flowing into the bright parenchyma hematoma.
Clinical features of basal ganglia hemorrhage include focal neurologic signs, headache, nausea, vomiting, decreased level of ... Basal ganglia hemorrhage (CT). Axial CT of the brain shows a large hyperdense region centered at the level of the right basal ... Basal ganglia hemorrhage (CT). Axial CT of the brain shows a large hyperdense region centered at the level of the right basal ... The most common location for a basal ganglia hemorrhage is the putamen (132; 91). Putaminal hemorrhage in the dominant ...
Such hemorrhages are typically located in the basal ganglia, cerebellum, or occipital lobes. Other location such as bleed ... It can cause epidural hemorrhage, subdural hemorrhage, and subarachnoid hemorrhage. Other condition such as hemorrhagic ... Basal ganglia, posterior fossa, and brainstem are spared. Boston criteria is used to determine the likelihood of a cerebral ... Types of intracranial hemorrhage are roughly grouped into intra-axial and extra-axial. Intra-axial hemorrhage is bleeding ...
Basal ganglia infarction or hemorrhage. * Vasculopathies/vasculitis: Churg-Strauss syndrome [4] , moyamoya ... Sydenhams chorea: magnetic resonance imaging of the basal ganglia. Neurology. 1995 Dec. 45(12):2199-202. [QxMD MEDLINE Link]. ... One study reported an increase in basal ganglia volume consistent with localized swelling. Follow-up studies may show ... Anticonvulsant drugs may suppress chorea but also may induce chorea, especially in patients with basal ganglia dysfunction. ...
Clinical changes of serum melatonin and ICAM-1 levels in patients with basal ganglia hypertensive intracerebral hemorrhage * ... Keywords: Serum melatonin, Intercellular adhesion molecule-1, Basal ganglia cerebral hemorrhage Abstract. Objective: To ... levels in patients with basal ganglia hypertensive intracerebral hemorrhage (HICH).. Methods: In this retrospective ... Clinical changes of serum melatonin and ICAM-1 levels in patients with basal ganglia hypertensive intracerebral hemorrhage. ...
Previous reports have demonstrated that intraventricular neurocytoma may present with tumor hemorrhage. In this case, an ... Basal Ganglia Cerebrovascular Disease / diagnosis* * Basal Ganglia Cerebrovascular Disease / etiology * Brain Neoplasms / ... We present the first reported case of a central neurocytoma in a patient with intraventricular hemorrhage caused by rupture of ... A neurocytoma and an associated lenticulostriate artery aneurysm presenting with intraventricular hemorrhage: case report ...
Head CT shows small intracerebral hemorrhage foci (vertical closed arrow). Basal ganglia can also not be visualized because of ... The closed arrowhead shows small intracerebral hemorrhage foci on the right temporal lobe, and the curved arrow shows the ...
There were four basal ganglia and six hemispheric hemorrhages. Seven patients had occlusion of the lenticulostriate arteries on ... In the three patients with lenticulostriate occlusion and basal ganglia hemorrhage, the average time to treatment was 5.2 hours ... with three resulting in basal ganglia hemorrhage. Although the population size was too small to show statistical significance, ... the time to treatment appeared to be an important factor in the lenticulostriate occlusions and basal ganglia hemorrhages. ...
Hypertension and cerebral amyloid angiopathy (CAA) are the most common causes of primary ICH, but the mechanism of hemorrhage ... First described as the source of bleeding in hypertensive hemorrhage, they are also one of the CAA-associated microangiopathies ... Intracerebral hemorrhage (ICH) is a significant cause of morbidity and mortality worldwide. ... As CAA rarely involves the basal ganglia, the basal ganglia CBAs in five subjects, all with history of hypertension, are likely ...
Histological studies revealed slight edema and small hemorrhages in the CNS (especially basal ganglia and Ammons horn). ...
... one of the basal ganglia). At least half of all patients who have this kind of hemorrhage have a history of hypertension. ... This is a large intracerebral hemorrhage. In this case, we believe that bleeding involved a small penetrating artery vessel ...
Intracerebral hemorrhage (ICH) in children is a rare but disabling disease that accounts for almost half cases of stroke. We ... primarily involved the basal ganglia and thalamus. Of the lobar cases, 21 cases were predominantly frontal, 4 cases were ... Spectrum of Intracerebral Hemorrhage in Children: A Report from PICU of a Resource Limited Country. Qalab Abbas. ,1Qurat ul Ain ... C. L. Lin, J. K. Loh, A. L. Kwan, and S. L. Howng, "Spontaneous intracerebral hemorrhage in children," The Kaohsiung Journal of ...
For example my hubby had a brain hemorrhage at the right basal ganglia, what types of affects should be anticipated? ... Google says that a right-sided basal ganglia stroke can make it difficult for someone to perceive sensations on their left side ...
... demonstrates focal enhancement in the left basal ganglia (arrow). (C, D) CT angiograms obtained in the (C) second and (D) third ... The first, "CT of Ongoing Intracerebral Hemorrhage," is by a group at the Peoples Hospital of Deyang City in Sichuan, China. ... A) Axial noncontrast CT image of the head shows no intracerebral hemorrhage. (B) Arterial phase CT angiogram obtained 192 ... The image captured the rapid evolution of a progressively expanding intracerebral hemorrhage in a 73-year-old man. ...
Basal ganglia infarctions. Abnormal magnetic resonance imaging (MRI) findings of the head have been reported in up to 90% of ... intracranial hemorrhage, and central nervous system lesions, all of which can occur in pregnancy and present with seizures. ... if clinical evidence of meningitis or concern for hemorrhage exists), determination of electrolyte levels, and urine or serum ... as well as cortical edema and hemorrhage. The syndrome of posterior reversible encephalopathy (PRES), indicative of central ...
... microvascular haemorrhage is thought to be a probable cause of DS. Radiological abnormalities disappeared following improved ... Basal ganglia lesions on MRI remained 4 weeks after the onset. However, these findings disappeared 13 weeks after the onset. ... CT scans showed high-intensity lesions in bilateral basal ganglia (figure 1A). MRI shows increased signal intensity on T1- ... A) CT scans showed high-intensity lesions in the basal ganglia bilaterally. (B) MRI showed increased signal intensity on T1- ...
Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up. J Neurol Sci 2009;287:100-104. ... Burr hole craniectomy of hypertensive basal ganglia hemorrhage can decrease brain edema grades and reduce secondary injury by ... most of which are components of capillary basal membranes. So MMP-2 activation leads to basal membrane degradation that is a ... Mechanism and Therapy of Brain Edema after Intracerebral Hemorrhage Subject Area: Cardiovascular System , Neurology and ...
... demonstrates focal enhancement in the left basal ganglia (arrow). (C, D) CT angiograms obtained in the (C) second and (D) third ... The first, "CT of Ongoing Intracerebral Hemorrhage," is by Chun Ma and Yi Zhou with imaging that captured the rapid evolution ... A) Axial noncontrast CT image of the head shows no intracerebral hemorrhage. (B) Arterial phase CT angiogram obtained 192 ... at basal lateral and inferior wall, indicating myocardial edema. (B) Late gadolinium enhancement image in short-axis view shows ...
A CT revealed bilateral hypodensities involving basal ganglia and internal capsule. Three days later, he had cardiorespiratory ... Postmortem examination of the brain revealed an extensive subarachnoid hemorrhage primarily located at the base of the brain ... Five presented with unilateral strokes involving the basal ganglia or thalamus, and three had bihemispheric involvement. Only ... calcifications of the basal ganglia, and HIV-associated encephalitis.1-3 Cognitive decline and signs of pyramidal tract ...
... which in hypertensive ICH is frequently located in the basal ganglia, thalamus, pons, and cerebellum. However, in patients who ... INTRACRANIAL HEMORRHAGE. Patients with intracranial hemorrhage (ICH), like those with AIS, often present with extremely ... Anticoagulant-associated intracerebral hemorrhage. Brain Hemorrhages 2020;1(1):89-94. [Context Link] ... Qureshi AI, et al Intensive blood-pressure lowering in patients with acute cerebral hemorrhage. N Engl J Med 2016;375(11):1033- ...
... techniques for evacuation of hematoma in basal ganglia on cortical spinal tract from patients with spontaneous hemorrhage: ... Prediction of Functional Outcome in Acute Cerebral Hemorrhage Using Diffusion Tensor Imaging at 3T: A Prospective Study ... Prediction of Functional Outcome in Acute Cerebral Hemorrhage Using Diffusion Tensor Imaging at 3T: A Prospective Study ... Bilateral substantia nigra and pyramidal tract changes following experimental intracerebral hemorrhage: an MR diffusion tensor ...
Brain MRI revealed abnormal lesions in the fornix, corpus callosum, basal ganglia and frontal lobe. Steroid therapy ameliorated ... A case of cholesterol embolization syndrome with cognitive impairment and pulmonary hemorrhage. Masayuki Moriya, M.D., Ph.D.1)2 ... His autopsy revealed severe pulmonary hemorrhage with alveolar vasculitis and cholesterol crystals in the brain, kidneys, liver ... cholesterol embolization to multiple organs including the brain induced systemic vasculitis that caused pulmonary hemorrhage ...
This revealed a hemorrhage into the basal ganglia and ventricles. There was mild ventriculomegaly and the basal cisterns were ...
13, 22] In cases of DKC caused by TINF2 mutations, basal ganglia calcification and pulmonary fibrosis have been reported. [22, ... 23] Revesz syndrome mainly manifests as bilateral exudative retinopathy (including hemorrhages and other vascular ...
Cerebral haemorrhage. Definition: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL ... intracerebral hemorrhages, intracerebral haemorrhage, cerebral haemorrhages, cerebral hemorrhages, Brain haemorrhage More ... Synonyms (terms occurring on more labels are shown first): cerebral hemorrhage, cerebral bleeding, cerebral haemorrhage, ...
... basal ganglia, and subcortical white matter. Petechial hemorrhages developed in bilateral corticospinal tracts and subcortical ... and basal ganglia. While the clinical symptoms and neuroimaging changes are usually reversible, persistent encephalopathy with ... Major hemorrhage occurred in 23 patients (0.9%) receiving clopidogrel plus aspirin and in 10 patients (0.4%) receiving aspirin ... Stereology studies found that the number and size of basal forebrain cholinergic neurons, which are normal in APP(L/S) mice, ...
An intracerebral hemorrhage is caused by bleeding in the brain. ... of having a type of stroke called an intracerebral hemorrhage, ... The non-lobe area primarily includes the basal ganglia, thalamus, cerebellum, and brainstem. ... They also looked at 1,175 people with an average age of 75 who had an intracerebral hemorrhage in the non-lobe parts of the ... and non-lobe areas of the brain to see if location was a factor for statin use and the risk of a first intracerebral hemorrhage ...
Basal ganglia and brainstem abnormalities occur in more critically ill patients. Cerebral angiography has been performed in a ... This may result in petechial hemorrhage or gross intracranial hemorrhage. The upper limit of autoregulation varies from one ... Subarachnoid or intraventricular hemorrhages may be seen in the most severe cases. Magnetic resonance imaging (MRI) is more ... This indicates that continual basal release of NO from endothelial cells keeps the vasculature in a dilated state. NO acts only ...
  • Magnetic Resonance Imaging was used to assess regional volumes of brain IDs in basal ganglia, brainstem, white matter, thalamus, and cortex/border with the corticomedullary junction, using a fully automatic assessment procedure followed by individual checking/correction where necessary. (springer.com)
  • FDG-PET revealed severe hypometabolism in the left cerebral hemisphere, including basal ganglia and thalamus, and hypermetabolism in the right cerebral hemisphere. (koreamed.org)
  • The thalamus/basal ganglion regions were involved in 46% of the cases. (elsevierpure.com)
  • He described both intracerebral hemorrhage and subarachnoid hemorrhage. (medlink.com)
  • Intracranial hemorrhage refers to any bleeding within the cranial vault, including subdural and epidural hematomas and subarachnoid hemorrhage. (medlink.com)
  • It can cause epidural hemorrhage, subdural hemorrhage, and subarachnoid hemorrhage. (wikipedia.org)
  • However, MRI has higher sensitivity than CT scan for the detection of epidural hemorrhage, subdural hemorrhage, subarachnoid hemorrhage, nonhemorrhagic cortical contusions, hemorrhagic parenchymal contusions, brainstem injuries, and white matter axonal injuries. (wikipedia.org)
  • Extra-axial hemorrhage, bleeding that occurs within the skull but outside of the brain tissue, falls into three subtypes: epidural hematoma, subdural hematoma, and subarachnoid hemorrhage. (wikipedia.org)
  • Four hours later, she developed a parenchymal hemorrhage in the left basal ganglia without subarachnoid hemorrhage. (surgicalneurologyint.com)
  • 4 ] Intracranial ICA dissection typically presents as severe headache, immediately followed by neurological symptoms of cerebral ischemia or subarachnoid hemorrhage. (surgicalneurologyint.com)
  • Cervicocephalic artery dissection can result in ischemic stroke or subarachnoid hemorrhage, affecting young or middle-aged adults [ 1 , 2 ]. (neurointervention.org)
  • This category includes intraparenchymal hemorrhage, or bleeding within the brain tissue, and intraventricular hemorrhage, bleeding within the brain's ventricles (particularly of premature infants). (wikipedia.org)
  • We present the first reported case of a central neurocytoma in a patient with intraventricular hemorrhage caused by rupture of an aneurysm on a lenticulostriate artery that supplied the tumor. (nih.gov)
  • A 35-year-old man who presented with an intraventricular hemorrhage underwent magnetic resonance imaging and cerebral angiography that disclosed a right lateral intraventricular mass and a 7-mm fusiform aneurysm from a lateral lenticulostriate branch of the right middle cerebral artery. (nih.gov)
  • Previous reports have demonstrated that intraventricular neurocytoma may present with tumor hemorrhage. (nih.gov)
  • F) Follow-up noncontrast CT image obtained 1 hour after the third phase CT angiogram shows massive enlargement of the hematoma, intraventricular hemorrhage, hydrocephalus, and subfalcine herniation. (auntminnie.com)
  • If the hemorrhage ruptures into the ventricular system (intraventricular hemorrhage), blood may cause acute hydrocephalus, which is an independent predictor for a worse outcome after intracerebral hemorrhage. (msdmanuals.com)
  • To investigate the clinical changes of serum melatonin and intercellular adhesion molecule-1 (ICAM-1) levels in patients with basal ganglia hypertensive intracerebral hemorrhage (HICH). (org.pk)
  • Hou H, Li X. Clinical changes of serum melatonin and ICAM-1 levels in patients with basal ganglia hypertensive intracerebral hemorrhage. (org.pk)
  • B) Arterial phase CT angiogram obtained 192 seconds later, after administration of contrast material, demonstrates focal enhancement in the left basal ganglia (arrow). (auntminnie.com)
  • Lobar intracerebral hemorrhages (hematomas in the cerebral lobes, outside the basal ganglia) usually result from angiopathy due to amyloid deposition in cerebral arteries (cerebral amyloid angiopathy), which affects primarily older people. (msdmanuals.com)
  • CT scans showed high-intensity lesions in bilateral basal ganglia ( figure 1A ). (bmj.com)
  • Basal ganglia lesions on MRI remained 4 weeks after the onset. (bmj.com)
  • A) CT scans showed high-intensity lesions in the basal ganglia bilaterally. (bmj.com)
  • Brain MRI revealed abnormal lesions in the fornix, corpus callosum, basal ganglia and frontal lobe. (neurology-jp.org)
  • A brain magnetic resonance imaging revealed lesions in the upper part of the genu and body in the corpus callosum as well as hemorrhage in the inter-hemispheric fissure. (koreamed.org)
  • The most common cause of basal ganglia is hypertension. (medlink.com)
  • Non-traumatic causes of hemorrhage includes: hypertension, cerebral amyloid angiopathy, hemorrhagic conversion of ischemic infarction, cerebral aneurysms, dural arteriovenous fistulae, cerebral venous sinus thrombosis, cerebral vasculitis and mycotic aneurysm. (wikipedia.org)
  • More than half of all cases of intracranial hemorrhage are the result of hypertension. (wikipedia.org)
  • Hypertension and cerebral amyloid angiopathy (CAA) are the most common causes of primary ICH, but the mechanism of hemorrhage in both conditions is unclear. (nature.com)
  • In hypertension, the cause of hemorrhage is thought to be elevated blood pressure-induced degenerative changes in the penetrating arterioles leading to rupture [ 14 ]. (nature.com)
  • At least half of all patients who have this kind of hemorrhage have a history of hypertension. (umassmed.edu)
  • The most common location for hemorrhage due to hypertension is the putamen. (msdmanuals.com)
  • Use of cocaine or, occasionally, other sympathomimetic drugs or medications can cause transient severe hypertension leading to hemorrhage. (msdmanuals.com)
  • Chronic arterial hypertension leads to formation of microaneurysms (Charcot-Bouchard aneurysms) in small perforating arteries, which may rupture and cause intracerebral hemorrhage. (msdmanuals.com)
  • A head CT scan was obtained in all patients prior to angiography to exclude hemorrhage and other mimics of ischemic stroke. (ajnr.org)
  • Here, we report a case of intracranial ICA dissection with ischemic onset, with a complication of remote parenchymal hemorrhage due to a recanalized dissected perforator following endovascular therapy. (surgicalneurologyint.com)
  • Callosal disconnection syndrome in a patient with corpus callosum hemorrhage: a diffusion tensor tractography study. (koreamed.org)
  • In this case, we believe that bleeding involved a small penetrating artery vessel supplying the putamen (one of the basal ganglia). (umassmed.edu)
  • compressing the brain stem and often causing secondary hemorrhages in the midbrain and pons. (msdmanuals.com)
  • It is caused by injuries of small arterial or venous vessels, causing hemorrhage within the brain parenchyma, and give rise to hyperdense lesion on CT scan. (wikipedia.org)
  • Only one of the 12 subjects with CBAs had a large ICH, and the etiology underlying the hemorrhage was likely multifactorial. (nature.com)
  • Through the years, intracerebral hemorrhage has also been termed "cerebral hemorrhage," "intracranial hemorrhage," "hemorrhagic stroke," and "cerebral bleed. (medlink.com)
  • Successful reperfusion is associated with a better outcome, and the prevalence of hemorrhage does not exceed that which occurs in the natural history of embolic stroke. (ajnr.org)
  • Intracerebral hemorrhage (ICH) in children is a rare but disabling disease that accounts for almost half cases of stroke. (hindawi.com)
  • Intracerebral hemorrhage (ICH) is a subtype of stroke with a severe high mortality and disability rate and accounts for about 10-15% of all strokes. (karger.com)
  • People who take cholesterol-lowering drugs called statins may have a lower risk of having a type of stroke called an intracerebral hemorrhage, according to a new study published in the December 7, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. (worldhealth.net)
  • While statins have been shown to reduce the risk of stroke from blood clots, there has been conflicting research on whether statin use increases or decreases the risk of a person having a first intracerebral hemorrhage," said study author David Gaist, MD, Ph.D., of the University of Southern Denmark in Odense and a member of the American Academy of Neurology. (worldhealth.net)
  • The memory system of the 'cortex - basal ganglia - thalamic loop' model suggests a need for the participation of the prefrontal lobe (PL) and basal ganglia (BG). (oatext.com)
  • Hemorrhage may involve any part of the CEREBRAL CORTEX and the BASAL GANGLIA. (ucdenver.edu)
  • B) MRI showed increased signal intensity on T1-weighted images in the bilateral basal ganglia. (bmj.com)
  • of the head shows fronto-temporal atrophy carnitine levels in urine were elevated and and bilateral subdural haemorrhage glutaryl-CoA dehydrogenase activity in cul- tured fibroblasts was low. (who.int)
  • His autopsy revealed severe pulmonary hemorrhage with alveolar vasculitis and cholesterol crystals in the brain, kidneys, liver, and the other organs. (neurology-jp.org)
  • It was possible that cholesterol embolization to multiple organs including the brain induced systemic vasculitis that caused pulmonary hemorrhage and his critical prognosis. (neurology-jp.org)
  • They were first described by Charcot and Bouchard in 1868 as a cause of hypertensive hemorrhage when they rupture [ 18 , 19 ]. (nature.com)
  • Intracerebral hemorrhage refers specifically to bleeding within the brain parenchyma. (medlink.com)
  • Intracerebral hemorrhage is focal bleeding from a blood vessel in the brain parenchyma. (msdmanuals.com)
  • Poor outcome or death is associated with nonrecanalization, older age, hemorrhage, and ICA bifurcation occlusions. (ajnr.org)
  • Comparison of TMS and DTT for predicting motor outcome in intracerebral hemorrhage. (koreamed.org)
  • Hemorrhage associated with central neurocytoma has been described previously, but never in association with an aneurysm originating from a feeding artery. (nih.gov)
  • BACKGROUND: Subcortical injury resulting from conventional surgical management of intracranial hemorrhage may counteract the potential benefts of hematoma evacuation. (elsevierpure.com)
  • Their article sparked controversy in the literature, prompting others to point out that such patients were at risk of hemorrhage and ischemia, and, thus, the syndrome was not necessarily "reversible. (medlink.com)
  • Basal ganglia hemorrhage is one of the most severe strokes. (medlink.com)
  • Most patients could survive the initial injury of smaller hemorrhage, but the secondary injury may result in severe neurological deficits and even death [ 4 ]. (karger.com)
  • This update highlights important clinical trial results on the treatment of intracerebral hemorrhage, including blood pressure management and surgery. (medlink.com)
  • Hemorrhage occurred in 10 of the 26 patients, with clinical deterioration in three. (ajnr.org)
  • Over 80% of children with AIDS have CNS involvement including acquired microcephaly, diffuse cerebral atrophy, calcifications of the basal ganglia, and HIV-associated encephalitis. (neurology.org)
  • Two CBAs in the basal ganglia demonstrated associated microhemorrhages, while three demonstrated infarcts in the vicinity. (nature.com)
  • We investigated differential characteristic of working memory and learning ability caused by a unilateral basal ganglia lesion (BGL) and a prefrontal lobe lesion (PLL) to provide a strategy for cognitive rehabilitation. (oatext.com)
  • 24 h presented complete effacement of basal cisterns (p = 0.005), sulcular effacement (p = 0.013), loss of cortico-subcortical differentiation (p = 0.0001) and effacement of the suprasellar cistern (p = 0.005). (medintensiva.org)
  • Movement disorders (particularly chorea, athetosis, and dystonia) are thought to result from basal ganglia pathology. (medscape.com)
  • The most common causes of metastatic intracerebral hemorrhage include melanoma, renal cell carcinoma, and choriocarcinoma. (msdmanuals.com)
  • The inflammatory reaction in the basal cistern causes the development of thick gelatinous exudate, which eventually encases the surrounding cranial nerves. (ina-jns.org)
  • Surgical treatment has a limited role in the treatment of intracerebral hemorrhage. (medlink.com)
  • A) T2-weighted short inversion time inversion recovery MRI scan at 1.5 T in short-axis view shows focal high-signal intensities (arrow) at basal lateral and inferior wall, indicating myocardial edema. (auntminnie.com)
  • Most patients with basal ganglia hemorrhage have high blood pressure. (medlink.com)
  • The average dose of urokinase was higher in the hemorrhage group, and mortality was higher in patients who hemorrhaged. (ajnr.org)
  • CT hyperintensity and increased signal intensity on T1WI MRI in basal ganglia are characteristic findings observed in 79% and 95% of patients with DS, respectively. (bmj.com)
  • Among them, similar radiological findings on basal ganglia can be observed in patients with Wilson's disease, hepatic encephalopathy and poisoning (manganese and organic mercury). (bmj.com)
  • Despite the well-known risk factors, the pathogenesis of ICH is unclear, and the site of bleeding has rarely been demonstrated histologically due to the difficulty in examining tissue destroyed by hemorrhage as well as secondary bleeding caused by the disruption of surrounding arteries [ 12 , 13 ]. (nature.com)