Autistic Disorder: A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)Asperger Syndrome: A disorder beginning in childhood whose essential features are persistent impairment in reciprocal social communication and social interaction, and restricted, repetitive patterns of behavior, interests, or activities. These symptoms may limit or impair everyday functioning. (From DSM-5)Child Development Disorders, Pervasive: Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements.Irritable Mood: Abnormal or excessive excitability with easily triggered anger, annoyance, or impatience.Social Behavior Disorders: Behaviors which are at variance with the expected social norm and which affect other individuals.Chromosomes, Human, Pair 15: A specific pair of GROUP D CHROMOSOMES of the human chromosome classification.Genetic Markers: A phenotypically recognizable genetic trait which can be used to identify a genetic locus, a linkage group, or a recombination event.Linkage Disequilibrium: Nonrandom association of linked genes. This is the tendency of the alleles of two separate but already linked loci to be found together more frequently than would be expected by chance alone.Case-Control Studies: Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.Anxiety Disorders: Persistent and disabling ANXIETY.Mood Disorders: Those disorders that have a disturbance in mood as their predominant feature.

*  "Causes" Acronym Resource and Erratum - The Environmental and Genetic Causes of Autism Reference...

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z A ACH acetylcholine ACMT American College of Medical Toxicology AD autistic ... disorder ADEM acute disseminated encephalomyelitis ADHD attention deficit hyperactivity disorder ADI-R Autism Diagnostic ... AD autistic disorder. ADEM acute disseminated encephalomyelitis. ADHD attention deficit hyperactivity disorder. ADI-R Autism ... ADSL autistic disorder with speech loss. ANCOVA analysis of covariance. ANOVA analysis of variance. APOE apolipoprotein E. ASD ...

*  Channelpedia

Autism is a psychiatric disorder with estimated heritability of 90%. One-third of autistic individuals experience seizures. A ... result in the seizure disorder GEFS+. To evaluate these sodium channel genes as candidates for the autism susceptibility locus ...

*  Autistic disorder definition | Drugs.com

Definition of autistic disorder. Provided by Stedman's medical dictionary and Drugs.com. Includes medical terms and definitions ... a severe form of pervasive developmental disorder.. *a diagnosis from the Diagnostic and Statistical Manual that is established ...

*  Gastrointestinal Factors in Autistic Disorder: A Critical Review | SpringerLink

... factors of autistic disorder (autism) has developed from descriptions of symptoms such as constipation and diarrhea in autistic ... factors of autistic disorder (autism) has developed from descriptions of symptoms such as constipation and diarrhea in autistic ... High prevalence of gastrointestinal symptoms in autistic children with autistic spectrum disorder Journal of Pediatric ... Patel N. C., Yeh J. Y., Shepherd M. D., Crismon M. L. (2002). Secretin treatment for autistic disorder: A critical analysis ...

*  What If You Had an Autistic Disorder and Didn't Know It? Tim Page's Memoir of Growing Up With Undiagnosed Asperger's Syndrome, ...

What If You Had an Autistic Disorder and Didn't Know It? Tim Page's Memoir of Growing Up With Undiagnosed Asperger's Syndrome ... what it's like to have his autistic disorder and not know it. And nothing in her review conflicts with what I know about Tim, ...

*  Facing Autism in New Brunswick: Do Study Results Involving High Functioning Autism Subjects Automatically Apply to Persons...

Labels: autism awareness, autism research, autistic disorder, cognitive impairment, high functioning autism, intellectual ... Do Study Results Involving High Functioning Autism Subjects Automatically Apply to Persons with Autistic Disorder and ... I understand the difficulties of working with a severely autistic child. My son is severely autistic. We have to learn ways to ... this gives people a lot of false impressions about typical autistic disorder. A lot of people would rather look at a LFA as ' ...

*  Autistic spectrum disorders | Nordoff Robbins

Read more about Music therapy in the assessment and treatment of autistic spectrum, disorder: Clinical application and research ... Music therapy in the assessment and treatment of autistic spectrum, disorder: Clinical application and research evidence.. ... Therapeutic Dialogues in Music: Nurturing Musicality of Communication in Children with Autistic Spectrum Disorder and Rett ... Evidence from assessment that can identify the expectations of music therapy as a treatment for autistic spectrum disorder (ASD ...

*  Facing Autism in New Brunswick: Autism Disorders and Intellectual Disability: Claim that 75-80% of Persons with Autistic...

... his book Autistic Symphony which rejects autism as a medical disorder: "Autistic Symphony offers a unique look at the ... Labels: AAP Management of Children with Autism Spectrum Disorders, Alan Griswold, autistic disorder, CDC, CPA, ICD, ... Autism Disorders and Intellectual Disability: Claim that 75-80% of Persons with Autistic Disorder are Intellectually Disabled ... My child has autistic disorder, cognitive impairments, and a borderline to low iq. To me he is high functioning, he can speak, ...

*  Health, Autistic Spectrum Disorder

In January of 2000 a group of parents proposed that Autistic Spectrum Disorder (ASD) may be the aftermath of exposure to ... Dr Bradstreet found the mercury burden in autistic children to be 8 times higher than in non-autistics. The main source of this ... OCD is obsessive, compulsive disorder and PANDAS is an acronym for "pediatric autoimmune psychiatric disorders associated with ... are elevated in individuals exhibiting autistic tendencies. There is also some evidence indicating that autistic children also ...

*  Autistic Spectrum Disorders Support Service - Trinity Disability Service - Trinity College Dublin

Autistic Spectrum Disorders Support Service Trinity College Dublin, like other third level institutions has seen a rise in the ... This webpage provides information and advice for students with Autistic Spectrum Disorders who are thinking about coming to ... links for student guides on helping you manage your role as a student with Asperger's Syndrome or Autistic Spectrum Disorder at ... one of the greatest increases in student numbers attending university are those individuals with Autistic Spectrum Disorders ( ...

*  Tagged Content - Doncaster Council - Content tagged with Autistic Spectrum Disorder - Tags

Autistic Spectrum Disorder. www.doncaster.gov.uk/services/schools/autistic-spectrum-disorder What is autistic spectrum disorder ...

*  Autistic Spectrum Disorder (ASD) and Epilepsy - Epilepsy Ireland

You are here: Home / Epilepsy Information / Epilepsy In Children / Epilepsy & Autism / Autistic Spectrum Disorder (ASD) and ... Genetic screening may be performed to identify disorders such as Fragile X which may underlie the neurological deficit in ...

*  Article: Athletes with ADHD & Autistic Spectrum Disorder (ASD) | Futurehealth

Autistic Spectrum Disorder (ASD) - # An estimated 8-10% (possibly up to 20%) professional athletes have ADHD (compared to four ... Athletes with ADHD & Autistic Spectrum Disorder (ASD). By Michael Linden (Page 1 of 1 pages) Permalink ... Advances in the Diagnosis & Treatment of ADD and Autistic Spectrum Disorder ADD Workshop ADD at Work, at Home Polycontrast ... Related Topic(s): Adhd; Anxiety; Aspergers; Athletic; Attention; Autistic Spectrum Disorder; Baseball; Brain; Neurofeedback; ...

*  Brain-specific autoantibodies in the plasma of subjects with autistic spectrum disorder. - PubMed - NCBI

Brain-specific autoantibodies in the plasma of subjects with autistic spectrum disorder.. Cabanlit M1, Wills S, Goines P, ... Although autism spectrum disorder (ASD) is diagnosed on the basis of behavioral parameters, several studies have reported ...

*  Education of Pupils with Autistic Spectrum Disorder at Dublin City University | gradireland

Understanding Autism: aims to provide a foundation in the history, concept and diagnosis of autistic spectrum disorder, causes ... a post currently funded by the Department of Education and Skills and who are currently working with students on the Autistic ... a post currently funded by the Department of Education and Skills and who are currently working with students on the Autistic ...

*  The Pediatrician's Role in the Diagnosis and Management of Autistic Spectrum Disorder in Children | AMERICAN ACADEMY OF...

... autism is often referred to as autistic spectrum disorder (ASD).2-5 This term encompasses the classic autistic disorder and ... autistic spectrum disorder • PDD-NOS = pervasive developmental disorder-not otherwise specified • MMR = measles-mumps-rubella ... 1996) Brief report: comorbid psychiatric disorders of autistic disorder. J Autism Dev Disord 26:159-163. ... 2000) Autistic spectrum disorders: when traditional medicine is not enough. Contemp Pediatr 17:101-116. ...

*  Autism | Development Disorder | Brain | Autistic | Kids | Health

... which makes it the perfect time for you to get educated on this disorder that affects your ability to communicate and interact ... Autism is a brain development disorder that typically appears during the first three years of life and affects your ability to ... April is Autism Awareness Month, which makes it the perfect time for you to get educated on this disorder. ...

*  Autistic Spectrum Disorder

... 10th November 2017 0 Studies in mice show promise for human treatment of 16p11.2 deletion syndrome. ... Browsing: Autistic Spectrum Disorder. In Case You Missed It 30th November 2017 0 ... The women who don't know they are autistic. Fabienne Cazalis and Adeline Lacroix report on the challenges faced by women with ...

*  Children with autistic spectrum disorders. I: Comparison of placebo and single dose of human synthetic secretin | Archives of...

Rett's disorder, childhood disintegrative disorder, Asperger's disorder, and pervasive developmental disorder (PDD), not ... PDD, pervasive developmental disorder. A utistic spectrum disorders (ASD) are heterogeneous, complex disorders with deficits in ... Children with autistic spectrum disorders. II: Parents are unable to distinguish secretin from placebo under double-blind ... Children with autistic spectrum disorders. I: Comparison of placebo and single dose of human synthetic secretin ...

*  Marketplace: Autistic Spectrum Disorder

Track your students' progress using real-time statistics.: What is it like to have Autistic Spectrum Disorder? What are the ... identified in enough people in the same kinds of ways to be labeled as a specific disorder such as Autistic Spectrum Disorder ( ... ASD), Attention Deficit/Hyperactivity Disorder (ADHD) and Dyslexia. ... Autistic Spectrum Disorder. What is it like to have Autistic Spectrum Disorder? What are the challenges someone with ASD faces ...

*  autistic spectrum disorders

Filed Under: Education Tagged With: ADD, ADHD, ASD, autistic spectrum disorders, behavior, HANDLE, LD, learning, learning ... Filed Under: Education, Family, HANDLE, Uncategorized Tagged With: ADD, ADD ADHD, adolescents, ASD, autistic spectrum disorders ... Naturopathic Medicine: Helping to Balance ADHD, LD, and Autistic Spectrum Challenges Naturally. March 29, 2011 by Sindy Leave a ...

*  What is Autistic Spectrum Disorder (ASD)?

... tailored care for adults with Autistic Spectrum Disorder & Aspergers Syndrome ... What is Autistic Spectrum Disorder (ASD)?. Autism is an increasingly well known disorder, first identified in 1943. People are ... However, few realise just how complex Autism, Aspergers & autistic spectrum disorders can be. ...

*  Autistic Spectrum Disorders: AKA PDD

Asperger's Disorder Autistic Disorder Rett Disorder Childhood Disintegrative Disorder PDD (NOS) Asperger's Disorder, Autism, ... Autistic Spectrum Disorders: AKA PDD James H. Johnson, Ph.D., ABPP University of Florida Pervasive Developmental Disorders: Old ... His views regarding this disorder have heavily influenced present day views of the disorder, Nature of the Disorder • Unlike ... Autistic Language Impairments • All autistic children show evidence of a severe language disorder. • Many remain mute. • Those ...

*  Famous People With Autism Spectrum Disorder: Autistic Celebrities (List)

There are many famous people throughout history that have been diagnosed with autism spectrum disorder (ASD). The diagnoses of ... Famous People with Autism Spectrum Disorder (List): Autistic Celebrities. Below is a list of famous people and celebrities (in ... Jonathan Lerman: This is an autistic savant from New York who is considered famous for his works as an artist. As a result of ... He is widely regarded as a pioneer for autistic writers.. Caiseal Mór: This is a renowned Australian author and musician. He is ...

*  Athletes with Autistic Spectrum Disorders

Sensory Issues with Autistic Spectrum Disorders. *Treating Autism with Vitamins and Supplements*Amino Acids for Autism, ... Athletes with Autistic Spectrum Disorders. By Jennifer Copley (Last Updated 22 May 2011) ... Contrary to popular belief, autistic spectrum disorders (ASDs) do not preclude athletic achievement, though athletes with ASDs ... For more articles on autistic spectrum disorders, visit the Autism and Asperger's Syndrome page.. ...

Focus on Autism and Other Developmental Disabilities: Focus on Autism and Other Developmental Disabilities is a peer-reviewed academic journal covering the field of special education. The editors-in-chief are Alisa K.Luke Jackson (author): Luke Christopher Jackson (born 18 August 1988) is the author of Freaks, Geeks, and Asperger Syndrome: A User Guide to Adolescence which was published 15th august 2002, a book penned from first-hand experience about his life with Asperger syndrome. He is also the author of "A User Guide to Cf/Gf Diet for Autism,Asperger Syndrome and ADHD" which was published in 2001.Relationship Development Intervention: Relationship Development Intervention (RDI) is a trademarked proprietary treatment program for autism spectrum disorders (ASD), based on the belief that the development of dynamic intelligence is the key to improving the quality of life for individuals with autism. The program's core philosophy is that individuals with autism can participate in authentic emotional relationships if they are exposed to them in a gradual, systematic way.Disequilibrium (medicine): Disequilibrium}}Nested case-control study: A nested case control (NCC) study is a variation of a case-control study in which only a subset of controls from the cohort are compared to the incident cases. In a case-cohort study, all incident cases in the cohort are compared to a random subset of participants who do not develop the disease of interest.Bipolar disorderMental disorderSocial anxiety disorder

(1/2366) Oculomotor evidence for neocortical systems but not cerebellar dysfunction in autism.

OBJECTIVE: To investigate the functional integrity of cerebellar and frontal systems in autism using oculomotor paradigms. BACKGROUND: Cerebellar and neocortical systems models of autism have been proposed. Courchesne and colleagues have argued that cognitive deficits such as shifting attention disturbances result from dysfunction of vermal lobules VI and VII. Such a vermal deficit should be associated with dysmetric saccadic eye movements because of the major role these areas play in guiding the motor precision of saccades. In contrast, neocortical models of autism predict intact saccade metrics, but impairments on tasks requiring the higher cognitive control of saccades. METHODS: A total of 26 rigorously diagnosed nonmentally retarded autistic subjects and 26 matched healthy control subjects were assessed with a visually guided saccade task and two volitional saccade tasks, the oculomotor delayed-response task and the antisaccade task. RESULTS: Metrics and dynamics of the visually guided saccades were normal in autistic subjects, documenting the absence of disturbances in cerebellar vermal lobules VI and VII and in automatic shifts of visual attention. Deficits were demonstrated on both volitional saccade tasks, indicating dysfunction in the circuitry of prefrontal cortex and its connections with the parietal cortex, and associated cognitive impairments in spatial working memory and in the ability to voluntarily suppress context-inappropriate responses. CONCLUSIONS: These findings demonstrate intrinsic neocortical, not cerebellar, dysfunction in autism, and parallel deficits in higher order cognitive mechanisms and not in elementary attentional and sensorimotor systems in autism.  (+info)

(2/2366) Genome-wide scan for autism susceptibility genes. Paris Autism Research International Sibpair Study.

Family and twin studies have suggested a genetic component in autism. We performed a genome-wide screen with 264 microsatellites markers in 51 multiplex families, using non-parametric linkage methods. Families were recruited by a collaborative group including clinicians from Sweden, France, Norway, the USA, Italy, Austria and Belgium. Using two-point and multipoint affected sib-pair analyses, 11 regions gave nominal P -values of 0.05 or lower. Four of these regions overlapped with regions on chromosomes 2q, 7q, 16p and 19p identified by the first genome-wide scan of autism performed by the International Molecular Genetic Study of Autism Consortium. Another of our potential susceptibility regions overlapped with the 15q11-q13 region identified in previous candidate gene studies. Our study revealed six additional regions on chromosomes 4q, 5p, 6q, 10q, 18q and Xp. We found that the most significant multipoint linkage was close to marker D6S283 (maximum lod score = 2.23, P = 0.0013).  (+info)

(3/2366) Clarifying an ambiguous functional analysis with matched and mismatched extinction procedures.

Results of functional analysis were ambiguous in suggesting that self-injurious behavior (SIB) was maintained by escape, sensory reinforcement, or both. To help clarify these results, we compared escape extinction, sensory extinction, and the combined treatments. Sensory extinction proved to be a necessary and sufficient treatment, whereas escape extinction failed to decrease SIB. These analyses helped to clarify the function of SIB and to identify an effective and efficient treatment.  (+info)

(4/2366) Is integer arithmetic fundamental to mental processing?: the mind's secret arithmetic.

Unlike the ability to acquire our native language, we struggle to learn multiplication and division. It may then come as a surprise that the mental machinery for performing lightning-fast integer arithmetic calculations could be within us all even though it cannot be readily accessed, nor do we have any idea of its primary function. We are led to this provocative hypothesis by analysing the extraordinary skills of autistic savants. In our view such individuals have privileged access to lower levels of information not normally available through introspection.  (+info)

(5/2366) Etiology of infantile autism: a review of recent advances in genetic and neurobiological research.

The etiology of autism is complex, and in most cases the underlying pathologic mechanisms are unknown. Autism is a hetereogeneous disorder, diagnosed subjectively on the basis of a large number of criteria. Recent research has investigated genetics, in utero insults and brain function as well as neurochemical and immunological factors. On the basis of family and twin studies, there appears to be a genetic basis for a wide "autistic syndrome." About a quarter of cases of autism are associated with genetic disorders such as fragile X syndrome or with infectious diseases such as congenital rubella. Genetic studies have shown an association between autism markers of brain development such as 3 markers of the c-Harvey-ros oncogene and the homeobox gene EN2. In some cases, autism is associated with insults early in gestation, including thalidomide embryopathy. Autism may arise from abnormal central nervous system functioning, since most autistic patients have indications of brain dysfunction, and about half of them have abnormal electroencephalograms. Similarly, the pattern of evoked response potentials and conduction time is altered in autistic children. There is substantial evidence from neuroimaging studies that dysfunctions in the cerebellum and possibly the temporal lobe and association cortex occur in autistic symptoms. Neurochemical studies have investigated the role of serotonin, epinephrine and norepinephrine, since levels of these neurotransmitters are altered in autism, although other hypotheses implicate overactive brain opioid systems and changes in oxytocin neurotransmission. Autoimmunity may also play a role; antibodies against myelin basic protein are often found in children with autism, who also have increased eosinophil and basophil response to IgE-mediated reactions. In summary, the prevailing view is that autism is caused by a pathophysiologic process arising from the interaction of an early environmental insult and a genetic predisposition.  (+info)

(6/2366) Heterogeneity and the genetics of autism.

The objective of this review is to summarize recent data on the genetics of autism, highlight the evidence for genetic heterogeneity and extend the implications of these findings for the identification of susceptibility genes in this disorder. Family studies have shown that autism runs in families and twin studies indicate that the basis of that familial aggregation is genetic. As a result the prospects for the identification of susceptibility genes using either linkage or association studies are quite good. However, recent evidence is accumulating suggesting that the disorder is genetically heterogeneous; higher functioning individuals with autism may arise from separate genetic mechanisms that lower functioning ones. If true, this will make the detection of linkage and association much more difficult.  (+info)

(7/2366) The puzzle of autism: an ophthalmologic contribution.

PURPOSE: A previous study of 86 thalidomide-affected subjects with ophthalmic manifestations revealed the unexpected finding of autism in 4 of the 5 severely retarded individuals. The subjects had anomalies associated with an early gestational effect of thalidomide, including facial nerve palsy and incomitant strabismus. Because autism has been observed in a few cases of Mobius sequence (Mobius syndrome), a condition characterized by involvement of the sixth and seventh cranial nerves, the similarity to early thalidomide embryopathy suggested a relation between cranial nerve involvement and autism. The present study was undertaken to further evaluate the association of autism with patients manifesting findings of Mobius syndrome. METHODS: A prospective study of 25 Swedish patients with Mobius sequence was conducted. The patients had a complete multidisciplinary evaluation, including ophthalmologic and psychiatric examinations and standard testing for autism. Findings associated with autism were compared with the ocular and systemic anomalies of the 4 thalidomide-affected subjects. RESULTS: In the Mobius group 6 patients had autism, achieving the criteria for autism according to all the diagnostic manuals that were used. One patient showed autistic-like conditions meeting fewer numbers of the criteria. A few were too young to be meeting evaluated. Incomitant strabismus ranging from primary abduction defects alone to a horizontal gaze paresis pattern was noted in these patients, in addition to characteristic findings of seventh nerve paresis. Aberrant lacrimation was observed in many cases, especially often associated with autism. CONCLUSION: The common group of anomalies noted in both cases of thalidomide embryopathy and Mobius sequence suggests that brain-stem damage probably early in embryogenesis can sometimes be associated with autism.  (+info)

(8/2366) Spatial attention deficits in patients with acquired or developmental cerebellar abnormality.

Recent imaging and clinical studies have challenged the concept that the functional role of the cerebellum is exclusively in the motor domain. We present evidence of slowed covert orienting of visuospatial attention in patients with developmental cerebellar abnormality (patients with autism, a disorder in which at least 90% of all postmortem cases reported to date have Purkinje neuron loss), and in patients with cerebellar damage acquired from tumor or stroke. In spatial cuing tasks, normal control subjects across a wide age range were able to orient attention within 100 msec of an attention-directing cue. Patients with cerebellar damage showed little evidence of having oriented attention after 100 msec but did show the effects of attention orienting after 800-1200 msec. These effects were demonstrated in a task in which results were independent of the motor response. In this task, smaller cerebellar vermal lobules VI-VII (from magnetic resonance imaging) were associated with greater attention-orienting deficits. Although eye movements may also be disrupted in patients with cerebellar damage, abnormal gaze shifting cannot explain the timing and nature of the attention-orienting deficits reported here. These data may be consistent with evidence from animal models that suggest damage to the cerebellum disrupts both the spatial encoding of a location for an attentional shift and the subsequent gaze shift. These data are also consistent with a model of cerebellar function in which the cerebellum supports a broad spectrum of brain systems involved in both nonmotor and motor function.  (+info)



spectrum disorders

  • In particular one of the greatest increases in student numbers attending university are those individuals with Autistic Spectrum Disorders (ASD). (tcd.ie)
  • This webpage provides information and advice for students with Autistic Spectrum Disorders who are thinking about coming to university and shares the experiences of TCD Students with ASD talking about their student life. (tcd.ie)
  • Children with autistic spectrum disorders. (bmj.com)
  • A utistic spectrum disorders (ASD) are heterogeneous, complex disorders with deficits in core symptoms of social interaction, communication, and behaviour. (bmj.com)
  • However, few realise just how complex Autism, Aspergers & autistic spectrum disorders can be. (moduscare.com)
  • In 2012, a researcher from the University of Nebraska at Kearney published a study reviewing research that had been done using the songbird as a model for autism spectrum disorders, noting that the neurobiology of vocalization is similar between humans and songbirds, and that, in both species, social learning plays a central role in the development of the ability to vocalize. (wikipedia.org)
  • Many causes of autism have been proposed, but understanding of the theory of causation of autism and the other autism spectrum disorders (ASD) is incomplete. (wikipedia.org)
  • Genetic factors may be the most significant cause for autism spectrum disorders. (wikipedia.org)
  • Autism spectrum disorders (ASD), including Asperger syndrome, are developmental disorders that begin in early childhood, persist throughout adulthood, and affect three crucial areas of development: communication, social interaction and restricted patterns of behavior. (wikipedia.org)
  • There are many conditions comorbid to autism spectrum disorders such as fragile X syndrome and epilepsy. (wikipedia.org)
  • Research in Autism Spectrum Disorders - Gluten-free and casein free diets in the treatment of autism spectrum disorders: A systematic review (2009) It concluded that the results "reveal that the current corpus of research does not support the use of GFCF diets in the treatment of ASD. (wikipedia.org)
  • Darold A. Treffert is a psychiatrist who specializes in the epidemiology of autism spectrum disorders and savant syndrome. (wikipedia.org)

symptoms

  • Interest in the gastrointestinal (GI) factors of autistic disorder (autism) has developed from descriptions of symptoms such as constipation and diarrhea in autistic children and advanced towards more detailed studies of GI histopathology and treatment modalities. (springer.com)
  • This defect by itself would not generally cause autistic symptoms to develop were it not for an added environmental insult that disabled the metallothionein proteins. (springboard4health.com)
  • 1 Because of qualitative and quantitative variations in symptoms, autism is often referred to as autistic spectrum disorder (ASD). (aappublications.org)
  • Among these factors, vaccines have attracted much attention, as parents may first become aware of autistic symptoms in their child around the time of a routine vaccination, and parental concern about vaccines has led to a decreasing uptake of childhood immunizations and an increasing likelihood of measles outbreaks. (wikipedia.org)
  • After she did so, Horvath injected Parker with an intravenous dose of secretin as part of his diagnostic tests, and according to his mother, Parker's autistic symptoms improved rapidly shortly thereafter. (wikipedia.org)
  • Distinguishing between ASDs and other diagnoses can be challenging because the traits of ASDs often overlap with symptoms of other disorders and the characteristics of ASDs make traditional diagnostic procedures difficult. (wikipedia.org)
  • Many anxiety disorders, such as social anxiety disorder, are not commonly diagnosed in people with ASD because such symptoms are better explained by ASD itself, and it is often difficult to tell whether symptoms such as compulsive checking are part of ASD or a co-occurring anxiety problem. (wikipedia.org)
  • Autism includes some symptoms commonly found in mood and anxiety disorders. (wikipedia.org)
  • In 1979, Jaak Panksepp proposed a connection between autism and opiates, noting that injections of minute quantities of opiates in young laboratory animals induce symptoms similar to those observed among autistic children. (wikipedia.org)

genetic

  • What are some of the other enzymatic (genetic) defects seen in autism and in what way do they cause the abnormalities seen in autistic children? (springboard4health.com)
  • Dr. Walsh hypothesizes that autistic children probably have a genetic or acquired defect in the function or activity of the metallothionein proteins. (springboard4health.com)
  • Genetic screening may be performed to identify disorders such as Fragile X which may underlie the neurological deficit in certain persons with autism and learning disability. (epilepsy.ie)
  • Autism is not a specific disease but rather a disorder of brain development with a strong genetic basis. (aappublications.org)
  • Most cases have no known cause, but the tendency for disorders of the autism spectrum to run in families suggests a genetic component. (wikipedia.org)
  • Selective mutism (the child just doesn't want to talk) Cerebral palsy (a movement disorder caused by brain damage) Genetic abnormalities - In 2005, researchers found a connection between expressive language delay and a genetic abnormality: a duplicate set of the same genes that are missing in sufferers of Williams-Beuren syndrome. (wikipedia.org)
  • The model advocates a variety of goals including increased awareness of autism prevalence, earlier and more accessible diagnosis, elimination of autistic behaviors through therapies such as applied behavior analysis, identification of environmental factors that may cause autism in infancy, and identification of a genetic marker to allow testing for autism in utero. (wikipedia.org)
  • Advocates for the medical model believe that autism is a disorder caused by genetic defects or environmental harm, that the value of talents attributed to autism does not outweigh the deficits, and that most autistic people would be better off if they were not autistic. (wikipedia.org)
  • About 10-15% of autism cases have an identifiable Mendelian (single-gene) condition, chromosome abnormality, or other genetic syndrome, and ASD is associated with several genetic disorders, perhaps due to an overlap in genetic causes. (wikipedia.org)
  • Autism has a strong genetic basis, although the genetics of autism is complex and it is unclear whether autism spectrum disorder (ASD) is explained more by multigene interactions or by rare mutations with major effects. (wikipedia.org)
  • The large number of autistic individuals with unaffected family members may result from copy number variations (CNVs)-spontaneous alterations in the genetic material during meiosis that delete or duplicate genetic material. (wikipedia.org)
  • Tourette syndrome is the more severe expression of a spectrum of tic disorders, which are thought to be due to the same genetic vulnerability. (wikipedia.org)

Facing Autism in New Brunswick

  • Facing Autism in New Brunswick: Do Study Results Involving High Functioning Autism Subjects Automatically Apply to Persons with Autistic Disorder and Intellectual Disabilities? (blogspot.com)

pervasive developmental disorder-not other

  • This statement focuses on autistic disorder and its milder variants, including Asperger syndrome and pervasive developmental disorder-not otherwise specified (PDD-NOS). (aappublications.org)

diagnosis

  • Understanding Autism: aims to provide a foundation in the history, concept and diagnosis of autistic spectrum disorder, causes and prevalence will also be considered. (gradireland.com)
  • Recent evidence that the prevalence of diagnosed ASD may be increasing and that early diagnosis and intervention are likely associated with better long-term outcomes 6-15 has made it imperative that pediatricians increase their fund of knowledge regarding the disorder. (aappublications.org)
  • ASD is a phenomenologic rather than an etiologic disorder (eg, trisomy 21 in Down syndrome), making the diagnosis more challenging. (aappublications.org)
  • Previously, the diagnosis manual DSM-IV did not allow the co-diagnosis of ASD and attention-deficit hyperactivity disorder (ADHD). (wikipedia.org)
  • Thus, individuals with autism spectrum disorder may also have a diagnosis of ADHD, with the modifiers of inattentive, hyperactive, combined-type, or not otherwise specified. (wikipedia.org)
  • Bipolar disorder, or manic-depression, is a highly controversial diagnosis and is itself often claimed to be comorbid with a number of conditions, including autism. (wikipedia.org)
  • Late talkers can often be misdiagnosed early on as having severe ("low-functioning") autism spectrum disorder (a category known simply as "autism", prior to the DSM-5), and careful professional evaluation is necessary for differential diagnosis, according to Darold Treffert and other experts. (wikipedia.org)

Asperger

  • Asperger syndrome, which is on the autistic spectrum, however, is not associated with language delay. (wikipedia.org)
  • The initial accounts of Asperger syndrome and other diagnostic schemes include descriptions of developmental coordination disorder. (wikipedia.org)
  • However, late language emergence can also be an early or secondary sign of high-functioning autism spectrum disorder / Asperger syndrome, or other developmental disorders, such as attention deficit hyperactivity disorder, intellectual disability, learning disability, social communication disorder, or specific language impairment. (wikipedia.org)

Behaviors

  • An expansion of the CGG trinucleotide repeat in the promoter of the gene FMR1 in boys causes fragile X syndrome, and at least 20% of boys with this mutation have behaviors consistent with autism spectrum disorder. (wikipedia.org)

ADHD

  • Several of these differences have been identified in enough people in the same kinds of ways to be labeled as a specific disorder such as Autistic Spectrum Disorder (ASD), Attention Deficit/Hyperactivity Disorder (ADHD) and Dyslexia. (symbaloo.com)

Hyperlexia

  • These are: Type 1: Hyperlexia marked by an accompanying language disorder. (wikipedia.org)
  • Type 2: Hyperlexia marked by an accompanying visual-spatial learning disorder. (wikipedia.org)

abnormalities

  • The brains of autistic individuals have abnormalities in both serotonin transporter and dopamine transporter binding. (blogspot.com)
  • Does it not seem reasonable that there might be different abnormalities involved in the neurological systems that result in some having High Functioning Autism as opposed to those with Autisic Disorder and cognitive impairment? (blogspot.com)
  • The theory that best accounts for most of the abnormalities in autism is that of metallothionein dysfunction, however many other biochemical abnormalities have been found in increased frequency in autistic individuals, and a number of these will be discussed in this chapter. (springboard4health.com)
  • Although autism spectrum disorder (ASD) is diagnosed on the basis of behavioral parameters, several studies have reported immune system abnormalities and suggest the possible role of autoimmunity in the pathogenesis of ASD. (nih.gov)
  • In an accompanying editorial, Pasquale Accardo and Howard Bostwick of New York Medical College wrote that Horvath's study "demonstrates consistent physiologic abnormalities (increased density of Paneth's cells along with diminished pancreatic secretin secretion) in autism that are not known to occur in any other specific gastrointestinal disorder. (wikipedia.org)

impairments

  • The pro-cure perspective is a view of autism as a disorder characterized by various impairments, mostly in communication and social interaction. (wikipedia.org)

traits

  • Type 3: Very early readers who are not on the autism spectrum, though they exhibit some "autistic-like" traits and behaviours which gradually fade as the child gets older. (wikipedia.org)
  • These innate personality traits can play a significant role not only in an individuals' predisposition to certain disorders, but also in their maintenance of those disorders. (wikipedia.org)
  • By understanding the specific temperamental traits that are common among individuals with specific disorders, clinicians can form a more targeted, informed approach to treatment and look to newer psychotherapies for guidance. (wikipedia.org)
  • Twin studies are a helpful tool in determining the heritability of disorders and human traits in general. (wikipedia.org)

prevalence

  • 17,18 The majority of studies of autistic disorder conducted through 1998 showed a prevalence of less than 1 per 1000. (aappublications.org)
  • The apparent increase may represent a combination of several factors, including changing criteria with inclusion of milder forms in the spectrum of autism, a higher public and professional recognition of the disorder, and a true rise in prevalence. (aappublications.org)

children with autism

  • To examine the effect of a single dose of human synthetic secretin (HSS) on behaviour and communication in children with autism spectrum disorder (ASD) using an objective measure of communication and social reciprocity and standardised rating scales. (bmj.com)
  • American Academy of Pediatrics - Clinical Report (2007) In their report, the AAP did not recommend the use of special diets for children with autism spectrum disorder because of inadequate evidence. (wikipedia.org)
  • Cochrane Library - Gluten and Casein-free diets in autism spectrum disorder (2008) The Cochrane review found that while relatively commonly used the evidence to support the diets use in children with autism was poor. (wikipedia.org)
  • Vanderbilt Evidence-based Practice Center - Therapies for Children with Autism Spectrum Disorder (2011) The review, commissioned by the Agency for Healthcare Research and Quality, concluded that, "the evidence supporting GFCF diets in ASD is limited and weak. (wikipedia.org)

brain

  • Brain-specific autoantibodies in the plasma of subjects with autistic spectrum disorder. (nih.gov)

syndrome

  • Therapeutic Dialogues in Music: Nurturing Musicality of Communication in Children with Autistic Spectrum Disorder and Rett Syndrome. (nordoff-robbins.org.uk)
  • The disturbance must not be better accounted for by Rett syndrome or childhood disintegrative disorder. (wikipedia.org)
  • There is evidence that shows valproic acid may increase the chance of polycystic ovary syndrome (PCOS) in women with epilepsy or bipolar disorder. (wikipedia.org)
  • The treatment for the spectrum of tic disorders is similar to the treatment of Tourette syndrome. (wikipedia.org)

Causes

  • However, there is increasing suspicion among researchers that autism does not have a single cause, but is instead a complex disorder with a set of core aspects that have distinct causes. (wikipedia.org)
  • His study, which included a total of 12 children, implied that the MMR vaccine causes autism and autistic enterocolitis. (wikipedia.org)

neurodevelopmental

  • The current scientific consensus is that no convincing scientific evidence supports these claims, and major scientific and medical bodies such as the Institute of Medicine and World Health Organization (WHO) as well as governmental agencies such as the U.S. Food and Drug Administration (FDA) and Centers for Disease Control and Prevention (CDC) reject any role for thiomersal in autism or other neurodevelopmental disorders. (wikipedia.org)
  • The fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), published in May 2013, reclassified Tourette's and tic disorders as motor disorders listed in the neurodevelopmental disorder category, removed the word "stereotyped" from the definition of tic to better distinguish between stereotypies and tics, and replaced transient tic disorder with provisional tic disorder, but made few significant other changes. (wikipedia.org)

developmental

  • a severe form of pervasive developmental disorder. (drugs.com)
  • A pervasive developmental disorder defined by the presence of abnormal and/or impaired development that is manifest before the age of 3 years, and by the characteristic type of abnormal functioning in all three areas of social interaction, communication, and restricted, repetitive behaviour. (blogspot.com)
  • 2-5 This term encompasses the classic autistic disorder and other pervasive developmental disorders. (aappublications.org)
  • 1 The disorders included in the spectrum (autism, Rett's disorder, childhood disintegrative disorder, Asperger's disorder, and pervasive developmental disorder (PDD), not otherwise specified) 2 represent a range of severity and underlying aetiologies. (bmj.com)
  • Being a twin Attention deficit hyperactivity disorder[citation needed] Autism (a developmental disorder) - There is strong evidence that autism is commonly associated with language delay. (wikipedia.org)
  • Constipation, often with overflow, or encopresis, is often associated with developmental disorders in children, and is often difficult to resolve, especially among those with behavioral and communication problems. (wikipedia.org)
  • They may show problems with proprioception (sensation of body position) on measures of developmental coordination disorder, balance, tandem gait, and finger-thumb apposition. (wikipedia.org)

behavior

  • Center for Autism and Related Disorders (CARD) is a therapy service that primarily provides families with applied behavior analysis. (wikipedia.org)

Asperger's

  • Persons diagnosed with Asperger's Disorder have average to above average intellectual functioning. (blogspot.com)

movement disorder

  • movements exhibited in stereotypic movement disorder or some autistic people, and the compulsions of obsessive-compulsive disorder (OCD) and seizure activity. (wikipedia.org)

High Functi

  • Can the results of studies involving subjects with High Functioning Autism automatically be applied to persons with Low Functioning Autism, to the 75-80% of persons with Autistic Disorder who are cognitively impaired? (blogspot.com)
  • If it is important to identify the subjects of a study as having High Functioning Autism, as having average or greater IQ's, is it valid to generalize those results to other persons with Autism Disorder and intellectual disabilities? (blogspot.com)

clinical

  • Music therapy in the assessment and treatment of autistic spectrum, disorder: Clinical application and research evidence. (nordoff-robbins.org.uk)

gastrointestinal

  • He is best known for proposing a link between secretin, gastrointestinal disorders and autism and for, as a result, proposing that secretin might be an effective treatment for autism. (wikipedia.org)
  • In 1999, Horvath published another study of 36 children, which concluded that "Unrecognized gastrointestinal disorders, especially reflux esophagitis and disaccharide malabsorption, may contribute to the behavioral problems of the non-verbal autistic patients. (wikipedia.org)

exhibit

  • In February 2000 William Walsh, Ph.D. of the Pfeiffer Treatment Center discovered that "most autistic patients exhibit evidence of diminished metallothionein (MT) activity and (that)…many of the classic features of autism can be explained by a compromised metallothionein system. (springboard4health.com)

heritability

  • Early studies of twins estimated the heritability of autism to be more than 90%--meaning that 90% of the differences between autistic and non-autistic individuals was due to genetics. (wikipedia.org)

seizure

  • For instance, then-president Liz Feld of Autism Speaks stated that one-third of people with autism also have a seizure disorder, half suffer serious digestive complications, 49 percent wander, and more than 30 percent are nonverbal. (wikipedia.org)

heterogeneous

  • It is now known to be a very heterogeneous disorder, with milder forms being more common than the classic form. (aappublications.org)

1943

  • Autism is an increasingly well known disorder, first identified in 1943. (moduscare.com)
  • In 1943, Kanner published his landmark paper, "Autistic Disturbances of Affective Contact," describing 11 children who were highly intelligent but displayed "a powerful desire for aloneness" and "an obsessive insistence on persistent sameness. (wikipedia.org)

secretin

  • Horvath originally became interested in the possible link between secretin and autism after being contacted by Victoria Beck, who brought in her autistic son, Parker, to see Horvath in April 1996. (wikipedia.org)

individuals

  • The RD temperament interacts with other temperaments and characters inherent in us enabling us to adapt to life experiences and influence susceptibility to emotional and behavioral disorders Two questionnaires were devised by Cloninger to measure the temperaments and characters of individuals. (wikipedia.org)
  • Individuals with autism spectrum disorder may benefit from additional types of medications. (wikipedia.org)
  • Mutations in different sets of genes may be involved in different autistic individuals. (wikipedia.org)

bipolar

  • Valproate (VPA), and its valproic acid, sodium valproate, and valproate semisodium forms, are medications primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches. (wikipedia.org)
  • It is used primarily to treat epilepsy and bipolar disorder. (wikipedia.org)
  • Valproate products are also used to treat manic or mixed episodes of bipolar disorder. (wikipedia.org)
  • Studies have shown this risk of PCOS is higher in women with epilepsy compared to those with bipolar disorder. (wikipedia.org)

Diagnostic

  • Diagnostic and statistical manual of mental disorders (3rd ed., revised). (springer.com)

disabilities

  • Many of the non-autistic co-twins had learning or social disabilities. (wikipedia.org)
  • When only one identical twin is autistic, the other often has learning or social disabilities. (wikipedia.org)

studies

  • Lindsay Oberman did this in her studies on Mu wave suppression in some high functioning autistics. (blogspot.com)
  • As I have told you before, the reasons that higher functioning autistics are used as research subjects in most studies, is that they involve compliance issues, such as the ability to sit still in an MRI scanner so as not to confound the results, or cooperate and learn a neurofeedback task such as mu supression, etc. (blogspot.com)
  • 16 Most of the more recent studies have revealed that a conservative estimate is approximately 1 in 1000 children for autistic disorder and 2 or more in 1000 children for ASD. (aappublications.org)

often

  • But Janet Maslin writes in today's New York Times that this "improbably lovely memoir" shows in "fascinatingly precise detail and often to pricelessly funny effect" what it's like to have his autistic disorder and not know it. (wordpress.com)
  • The relationship between temperament and individual clusters of DSM personality disorders is often investigated. (wikipedia.org)
  • One in four autistic children develops seizures, often starting either in early childhood or adolescence. (wikipedia.org)
  • Sowell claimed late talkers are often inaccurately categorized as having an autism spectrum disorder (ASD), and that a small subset of late talkers are highly intelligent children with common characteristics concentrated in music, memory, math or the sciences. (wikipedia.org)

intellectual

  • I have now provided 3 credible sources to support the 75-80% range of persons with Autistic Disorder as also being Intellectually disabled - the ICD, the CPA and the CDC and Mr. Griswold can only repeat his opposition to an association between Autistic Disorder and Intellectual Disability. (blogspot.com)
  • These figures and sources are my authorities for the upper end of the 75-80% range of persons with Autistic Disorder having an Intellectual Disability. (blogspot.com)

behaviour

  • The reason they aren't going to do testing on Low Function autistics is b/c they have to deal with behaviour, they have to do with non-verbal issues, and why should they bother. (blogspot.com)

cognitive

  • ASD is also associated with epilepsy, with variations in risk of epilepsy due to age, cognitive level, and type of language disorder. (wikipedia.org)

difficulties

  • I understand the difficulties of working with a severely autistic child. (blogspot.com)

Cite

  • I don't know as much about the study you are citing in this post, but in a well-done study, the authors in a discussion section will cite the limitations of the study, stating that the autistics were higher functioning than usual had average or close to average IQ's and admit they are not necessarily applicable to lower functioning autistics. (blogspot.com)

research

  • Low functioning autistics are not able to do these things, so they make for more difficult research subjects. (blogspot.com)
  • Music Therapy in the Education Service: Research with Autistic Children and their Mothers. (nordoff-robbins.org.uk)

individual

  • For each autistic individual, mutations in more than one gene may be implicated. (wikipedia.org)

among

  • Anxiety disorders are common among children and adults with ASD. (wikipedia.org)