No data available that match "Aging"

*  JCI - Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors
Proinflammatory cytokines, aging, and age-related diseases. J Am Med Dir Assoc. 2013;14(12):877-882.. View this article via: ... In senescence, age-associated B cells secrete TNFα and inhibit survival of B-cell precursors. Aging Cell. 2013;12(2):303-311. ... Miller JP, Allman D. Linking age-related defects in B lymphopoiesis to the aging of hematopoietic stem cells. Semin Immunol. ... BALB/c and C57BL/6 mice of different ages were purchased from the National Institute of Aging (NIA) or the National Cancer ...
*  "Polymorphism of age-dependent changes in the production of a thf helpe" by T Matsuzawa and B Cinader
Matsuzawa, T and Cinader, B, "Polymorphism of age-dependent changes in the production of a thf helper factor." (1982). Subject ... Polymorphism of age-dependent changes in the production of a thf helper factor. ...
*  RFA-AG-18-018: Development of Valid Reliable Markers of Aging-Related Biologic Mechanisms for Human Studies (U01)
Development of Valid Reliable Markers of Aging-Related Biologic Mechanisms for Human Studies (U01) RFA-AG-18-018. NIA ... It may be possible to prevent or ameliorate multiple adverse age-related outcomes by slowing or reversing aging changes though ... Use data from linked cohorts spanning different age ranges to examine relationships of markers to aging changes from early life ... individuals of differing ages and within the same age cohort, and assess their relationships in humans to in vivo functions ...
*  Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8+ T cells in aged...
We show differential onset of decline for several IAV-specific CD8+ T-cell populations with advanced age that parallel age- ... In advanced age, decreased CD8+ cytotoxic T-lymphocyte (CTL) responses to novel pathogens and cancer is paralleled by a decline ... Furthermore, naïve CD8+ T cells expressing high levels of CD44 accumulate with age, but it is unknown whether this accumulation ... Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8+ T cells in aged ...
*  Investigation of Transcriptome Dysregulation in Brain Ageing | babs
RNA sequencing reveals pronounced changes in the noncoding transcriptome of aging synaptosomes', Neurobiol Aging, 56:67-77. ... Human brain ageing is characterised by decreasing cognitive function of various severity affecting 60% of aged population. ... Diminished cognitive function with increased age is likely a manifestation of dysregulated synaptic function and ineffective ...
*  Age-related effects of the neuromodulator d-serine on neurotransmission and synaptic potentiation in the CA1 hippocampal area...
... but with a larger magnitude in aged rats, thus preventing the age-related decrease in NMDAr activation. d-serine also increased ... Circuit-specific changes in d-serine-dependent activation of the N-methyl-D-aspartate receptor in the aging hippocampus, AGE, ... Age-related effects of the neuromodulator d-serine on neurotransmission and synaptic potentiation in the CA1 hippocampal area ... J.-M. Billard, Serine racemase as a prime target for age-related memory deficits, European Journal of Neuroscience, 2013, 37, ...
*  Elderly at the bath: Medical Supplies for the elderly
Medical supplies for the elderly are especially helpful for allowing aged individuals to perform satisfactorily in the bathroom ... Medical supplies for the elderly are especially helpful for allowing aged individuals to perform satisfactorily in the bathroom ...
*  The Aging Brain: Why We Forget and What Might Help -
aging ala alc anti-aging avocado basil blues brain brain health cheese cilantro diabetes diet eating energy exercise fat food ... as we age. So, what's happening to us? Let's take a closer look at some of the scientific knowledge about the aging brain and ... This Research Update column highlights articles related to recent scientific inquiry into the process of human aging. It is not ... on levels of NMDAR in aged mice. The investigators suspected this antioxidant is an important piece of the age-associated ...
*  IJMS | Free Full-Text | Oxidative Stress and Epigenetic Regulation in Ageing and Age-Related Diseases | HTML
To understand the process leading to age-associated alterations is, therefore, of the highest relevance for the development of ... might orchestrate the progressive loss of control over biological homeostasis and the functional impairment typical of aged ... new treatments for age-associated diseases, such as cancer, diabetes, Alzheimer and cardiovascular accidents. Mechanistically, ... Stadtman, E.R. Protein oxidation in aging and age-related diseases. Ann. N. Y. Acad. Sci 2001, 928, 22-38. [Google Scholar] ...
*  Reading and solving arithmetic problems improves cognitive functions of normal aged people: a randomized controlled study |...
People generally believe the so-called mental-exercise hypothesis, that is, the age-related decline in cognitive fun ... The relationship between mental exercise and mental aging is a controversial issue. ... Salthouse TA (2006) Mental exercise and mental aging. Perspect Psychol Sci 1:68-87CrossRefGoogle Scholar ... Here, we introduce a new cognitive intervention program for normal aged people, the concept of which is derived from the ...
*  Age-related decrease in proteasome expression contributes to defective nuclear factor-κB activation during hepatic ischemia...
Age-related changes in the 20S and 26S proteasome activities in the liver of male F344 rats. Mech Ageing Dev 1998; 102: 55-66. ... Alteration of rat liver 20S proteasome activities by age and food restriction. J Gerontol A Biol Sci Med Sci 1996; 51: B316- ... Age-dependent responses to hepatic ischemia/reperfusion injury. Shock 2005; 24: 421-427.. *CrossRef, ... Age-related decrease in proteasome expression contributes to defective nuclear factor-κB activation during hepatic ischemia/ ...
*  The normal age variation in left ventricular parameters | Open-i
The normal age variation in left ventricular parameters in males (left) and females (right). Solid lines represent rational ... Results: Age and gender specific normal ranges for LV volumes, mass and function are presented from the second through the ... Results: Age and gender specific normal ranges for LV volumes, mass and function are presented from the second through the ... Conclusion: LV volumes, mass and function vary over a broad age range in healthy individuals. LV volumes and mass both rise in ...
*  Findings that something in your blood can influence the way you think could lead to new treatments for age-associated declines...
For largely unknown reasons, the hippocampus is especially vulnerable to normal aging, said Wyss-Coray. "With advancing age, ... Potential anti-aging component of cord blood refreshes minds of old mice on April 20, 2017 at 7:14 am The mice also got better ... Could Young Blood Boost Aging Brains? on April 20, 2017 at 2:21 am That led to a critical question: What is it about umbilical ... A protein from umbilical cords could revitalize memory in an aging brain on April 19, 2017 at 5:00 pm They also isolated the ...
*  Frontiers | Environmental enrichment strengthens corticocortical interactions and reduces amyloid-β oligomers in aged mice |...
... in aged wild-type mice. We analyzed the functional consequences of EE on aged brain physiology by performing in vivo local ... in aged wild-type mice. We analyzed the functional consequences of EE on aged brain physiology by performing in vivo local ... Considering the high social impact of the decline in brain performance associated to aging, there is an urgent need to better ... Considering the high social impact of the decline in brain performance associated to aging, there is an urgent need to better ...
*  National Institute on Aging
on health & aging & Alzheimer's. Get research news & funding opportunities from the National Institute on Aging at NIH. ... Global Aging. Find information on research into global trends in aging and aging-related diseases. ... Aging Research Advances. Since its founding in 1974, NIA research has changed the way America understands aging. ... Baltimore Longitudinal Study of Aging. The Baltimore Longitudinal Study of Aging is America's longest-running scientific study ...
*  Age of Autism Awards 2010: Dr. Paul Offit, Denialist of the Decade - AGE OF AUTISM
... after which an age-related decline dominates in the elderly. Based on a realistic age-structured model, we compare differences ... Posted by Age of Autism on December 29, 2010 at 05:45 AM in Abdulkadir Khalif, Anne Dachel, Cathy Jameson, Current Affairs, Dan ... Age of Autism Awards 2010: Dr. Paul Offit, Denialist of the Decade By Dan Olmsted ... He should wear his black hooded cloak and carry his sickle when he recieves this award for 'Monster of the Decade' from Age of ...
*  Understanding of gravity in the Middle Ages | Physics Forums - The Fusion of Science and Community
I would say yes if you are talking about a temporal frame of reference, i.e. Middle Ages vs. Information Age. ... Similar Discussions: Understanding of gravity in the Middle Ages * Middle of gravity (Replies: 5) ... I have read that in the Middle Ages people believed that angels pushed the Moon in its orbit, the angelic push presumably being ... What else did people in the Middle Ages know about gravity? Did they, for example, know that the same force which was ...
*  Media Use in School-Aged Children and Adolescents | From the American Academy of Pediatrics | Pediatrics
Pathological video-game use among youth ages 8 to 18: a national study. Psychol Sci. 2009;20(5):594-602pmid:19476590. ... It is estimated that ∼12% of youth aged 10 to 19 years have ever sent a sexual photo to someone else.44 The Internet also has ... A recent study found that TV hours among school-aged children have decreased in the past decade for children younger than 8 ... This policy statement focuses on children and adolescents 5 through 18 years of age. Research suggests both benefits and risks ...
*  Strongest Pill Ever. Age To Buy Viagra
Age To Buy Viagra. Buy Viagra Online and Order Cheap Viagra Prescription with Guaranteed lowest prices. ... Age To Buy Viagra. Here is the information you need. How does it work? Is it effective? What are the side effects. ... Foodstuff bleeding of age to buy viagra viagra has been reported.. After partner consumes it inside 5 ages, viagra she has ... How to age to buy viagra break a ed man symptom. For material this level stimulates you that will help you sustain throughout ...
*  aging-gi
In a study conducted to understand the effect of aging on carbohydrates digestion and absorption, both older and younger age ... manometric studies of the colon in the elderly fail to identify any age-related decrease in the motility. In the aged colon, ... but not in the younger age groups (3) . Finally, the brush border peptidases seem also to remain intact with older age, and ... it is worth mentioning that serum insulin levels increase with age, but the sensitivity to insulin diminishes with age (1) . ...
*  Rejuvenation (aging) - Wikipedia
Ageless Aging brain American Academy of Anti-Aging Medicine Biogerontology Biological immortality DNA repair DNA damage theory ... Life extension strategies often study the causes of aging and try to oppose those causes in order to slow aging. Rejuvenation ... de Grey, Aubrey; Rae, Michael (September 2007). Ending Aging: The Rejuvenation Breakthroughs that Could Reverse Human Aging in ... was applied as a robust method of decelerating aging and the development of age-related diseases. The biomedical gerontologist ...
*  Aging Rockers - latimes
Concerning Robert Hilburn's June 25 article, 'Never Too Old to Rock':The Who? My gosh--they died years ago, yet they continue to plague us.They stopped doing anything worthwhile a long time ago.
*  Aging/Gerontology - Neurotopia
Aging/Gerontology. Neurotopia. Category archives for Aging/Gerontology. Alzheimer's Disease and risky sexual behavior: not ...
*  Revisioning Aging
Aging: Encounters with the Medical Model - Rhonda Nay: Benevolent Oppression: Experiences of Older Women Aging «Out of Place ... Revisioning Aging Empowerment of Older Women. Series: *Eruptions: New Feminism Across the Disciplines ...
*  Aging | New York Post
Downing five pints of beer or glasses of wine a week does not lead to premature signs of aging. But heavy boozers have a " ... Shingles has long been a menace, especially for the stressed and the aging. The virus, which lies latent in those who've had ...

No data available that match "Aging"

(1/31363) The expiry date of man: a synthesis of evolutionary biology and public health.

In industrialised countries, mortality and morbidity are dominated by age related chronic degenerative diseases. The health and health care needs of future populations will be heavily determined by these conditions of old age. Two opposite scenarios of future morbidity exist: morbidity might decrease ("compress"), because life span is limited, and the incidence of disease is postponed. Or morbidity might increase ("expand"), because death is delayed more than disease incidence. Optimality theory in evolutionary biology explains senescence as a by product of an optimised life history. The theory clarifies how senescence is timed by the competing needs for reproduction and survival, and why this leads to a generalised deterioration of many functions at many levels. As death and disease are not independent, future morbidity will depend on duration and severity of the process of senescence, partly determined by health care, palliating the disease severity but increasing the disease duration by postponing death. Even if morbidity might be compressed, health care needs will surely expand.  (+info)

(2/31363) Developmental synaptic changes increase the range of integrative capabilities of an identified excitatory neocortical connection.

Excitatory synaptic transmission between pyramidal cells and fast-spiking (FS) interneurons of layer V of the motor cortex was investigated in acute slices by using paired recordings at 30 degrees C combined with morphological analysis. The presynaptic and postsynaptic properties at these identified central synapses were compared between 3- and 5-week-old rats. At these two postnatal developmental stages, unitary EPSCs were mediated by the activation of AMPA receptors with fast kinetics at a holding potential of -72 mV. The amplitude distribution analysis of the EPSCs indicates that, at both stages, pyramidal-FS connections consisted of multiple functional release sites. The apparent quantal size obtained by decreasing the external calcium ([Ca2+]e) varied from 11 to 29 pA near resting membrane potential. In young rats, pairs of presynaptic action potentials elicited unitary synaptic responses that displayed paired-pulse depression at all tested frequencies. In older animals, inputs from different pyramidal cells onto the same FS interneuron had different paired-pulse response characteristics and, at most of these connections, a switch from depression to facilitation occurred when decreasing the rate of presynaptic stimulation. The balance between facilitation and depression endows pyramidal-FS connections from 5-week-old animals with wide integrative capabilities and confers unique functional properties to each synapse.  (+info)

(3/31363) Low resting potential and postnatal upregulation of NMDA receptors may cause Cajal-Retzius cell death.

Using in situ patch-clamp techniques in rat telencephalic slices, we have followed resting potential (RP) properties and the functional expression of NMDA receptors in neocortical Cajal-Retzius (CR) cells from embryonic day 18 to postnatal day 13, the time around which these cells normally disappear. We find that throughout their lives CR cells have a relatively depolarized RP (approximately -50 mV), which can be made more hyperpolarized (approximately -70 mV) by stimulation of the Na/K pump with intracellular ATP. The NMDA receptors of CR cells are subjected to intense postnatal upregulation, but their similar properties (EC50, Hill number, sensitivity to antagonists, conductance, and kinetics) throughout development suggest that their subunit composition remains relatively homogeneous. The low RP of CR cells is within a range that allows for the relief of NMDA channels from Mg2+ blockade. Our findings are consistent with the hypothesis that CR cells may degenerate and die subsequent to uncontrolled overload of intracellular Ca2+ via NMDA receptor activation by ambient glutamate. In support of this hypothesis we have obtained evidence showing the protection of CR cells via in vivo blockade of NMDA receptors with dizocilpine.  (+info)

(4/31363) Somatic recording of GABAergic autoreceptor current in cerebellar stellate and basket cells.

Patch-clamp recordings were performed from stellate and basket cells in rat cerebellar slices. Under somatic voltage clamp, short depolarizing pulses were applied to elicit action potentials in the axon. After the action potential, a bicuculline- and Cd2+-sensitive current transient was observed. A similar response was obtained when eliciting axonal firing by extracellular stimulation. With an isotonic internal Cl- solution, the peak amplitude of this current varied linearly with the holding potential, yielding an extrapolated reversal potential of -20 to 0 mV. Unlike synaptic or autaptic GABAergic currents obtained in the same preparation, the current transient had a slow rise-time and a low variability between trials. This current was blocked when 10 mM BAPTA was included in the recording solution. In some experiments, the current transient elicited axonal action potentials. The current transient was reliably observed in animals aged 12-15 d, with a mean amplitude of 82 pA at -70 mV, but was small and rare in the age group 29-49 d. Numerical simulations could account for all properties of the current transient by assuming that an action potential activates a distributed GABAergic conductance in the axon. The actual conductance is probably restricted to release sites, with an estimated mean presynaptic current response of 10 pA per site (-70 mV, age 12-15 d). We conclude that in developing rats, stellate and basket cell axons have a high density of GABAergic autoreceptors and that a sizable fraction of the corresponding current can be measured from the soma.  (+info)

(5/31363) Fas/Apo [apoptosis]-1 and associated proteins in the differentiating cerebral cortex: induction of caspase-dependent cell death and activation of NF-kappaB.

The developing cerebral cortex undergoes a period of substantial cell death. The present studies examine the role of the suicide receptor Fas/Apo[apoptosis]-1 in cerebral cortical development. Fas mRNA and protein are transiently expressed in subsets of cells within the developing rat cerebral cortex during the peak period of apoptosis. Fas-immunoreactive cells were localized in close proximity to Fas ligand (FasL)-expressing cells. The Fas-associated signaling protein receptor interacting protein (RIP) was expressed by some Fas-expressing cells, whereas Fas-associated death domain (FADD) was undetectable in the early postnatal cerebral cortex. FLICE-inhibitory protein (FLIP), an inhibitor of Fas activation, was also expressed in the postnatal cerebral cortex. Fas expression was more ubiquitous in embryonic cortical neuroblasts in dissociated culture compared to in situ within the developing brain, suggesting that the environmental milieu partly suppresses Fas expression at this developmental stage. Furthermore, FADD, RIP, and FLIP were also expressed by subsets of dissociated cortical neuroblasts in culture. Fas activation by ligand (FasL) or anti-Fas antibody induced caspase-dependent cell death in primary embryonic cortical neuroblast cultures. The activation of Fas was also accompanied by a rapid downregulation of Fas receptor expression, non-cell cycle-related incorporation of nucleic acids and nuclear translocation of the RelA/p65 subunit of the transcription factor NF-kappaB. Together, these data suggest that adult cortical cell number may be established, in part, by an active process of receptor-mediated cell suicide, initiated in situ by killer (FasL-expressing) cells and that Fas may have functions in addition to suicide in the developing brain.  (+info)

(6/31363) Metrifonate increases neuronal excitability in CA1 pyramidal neurons from both young and aging rabbit hippocampus.

The effects of metrifonate, a second generation cholinesterase inhibitor, were examined on CA1 pyramidal neurons from hippocampal slices of young and aging rabbits using current-clamp, intracellular recording techniques. Bath perfusion of metrifonate (10-200 microM) dose-dependently decreased both postburst afterhyperpolarization (AHP) and spike frequency adaptation (accommodation) in neurons from young and aging rabbits (AHP: p < 0.002, young; p < 0.050, aging; accommodation: p < 0.024, young; p < 0.001, aging). These reductions were mediated by muscarinic cholinergic transmission, because they were blocked by addition of atropine (1 microM) to the perfusate. The effects of chronic metrifonate treatment (12 mg/kg for 3 weeks) on CA1 neurons of aging rabbits were also examined ex vivo. Neurons from aging rabbits chronically treated with metrifonate had significantly reduced spike frequency accommodation, compared with vehicle-treated rabbits. Chronic metrifonate treatment did not result in a desensitization to metrifonate ex vivo, because bath perfusion of metrifonate (50 microM) significantly decreased the AHP and accommodation in neurons from both chronically metrifonate- and vehicle-treated aging rabbits. We propose that the facilitating effect of chronic metrifonate treatment on acquisition of hippocampus-dependent tasks such as trace eyeblink conditioning by aging subjects may be caused by this increased excitability of CA1 pyramidal neurons.  (+info)

(7/31363) Thiamine deficiency is prevalent in a selected group of urban Indonesian elderly people.

This cross-sectional study involved 204 elderly individuals (93 males and 111 females). Subjects were randomly recruited using a list on which all 60-75 y-old-people living in seven sub-villages in Jakarta were included. The usual food intake was estimated using semiquantitative food frequency questionnaires. Hemoglobin, plasma retinol, vitamin B-12, red blood cell folate and the percentage stimulation of erythrocyte transketolase (ETK), as an indicator of thiamine status, were analyzed. Median energy intake was below the assessed requirement. More than 75% of the subjects had iron and thiamine intakes of approximately 2/3 of the recommended daily intake, and 20.2% of the study population had folate intake of approximately 2/3 of the recommended daily intake. Intakes of vitamins A and B-12 were adequate. Biochemical assessments demonstrated that 36.6% of the subjects had low thiamine levels (ETK stimulation > 25%). The elderly men tended to have lower thiamine levels than the elderly women. The overall prevalence of anemia was 28.9%, and the elderly women were affected more than the elderly men. Low biochemical status of vitamins A, B-12 and RBC folate was found in 5.4%, 8.8 % and 2.9% of the subjects, respectively. Dietary intakes of thiamine and folate were associated with ETK stimulation and plasma vitamin B-12 concentration (r = 0.176, P = 0.012 and r = 0.77, P = 0.001), respectively. Results of this study suggest that anemia, thiamine and possibly vitamin B-12 deficiency are prevalent in the elderly living in Indonesia. Clearly, micronutrient supplementation may be beneficial for the Indonesian elderly population living in underprivileged areas.  (+info)

(8/31363) High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice.

Semipurified diets incorporating either perilla oil [high in alpha-linolenate, 18:3(n-3)] or safflower oil [high in linoleate, 18:2(n-6)] were fed to senescence-resistant SAMR1 mouse dams and their pups. Male offspring at 15 mo were examined using behavioral tests. In the open field test, locomotor activity during a 5-min period was significantly higher in the safflower oil group than in the perilla oil group. Observations of the circadian rhythm (48 h) of spontaneous motor activity indicated that the safflower oil group was more active than the perilla oil group during the first and second dark periods. The total number of responses to positive and negative stimuli was higher in the safflower oil group than in the perilla oil group in the light and dark discrimination learning test, but the correct response ratio was lower in the safflower oil group. The difference in the (n-6)/(n-3) ratios of the diets reflected the proportions of (n-6) polyunsaturated fatty acids, rather than those of (n-3) polyunsaturated fatty acids in the brain total fatty acids, and in the proportions of (n-6) and (n-3) polyunsaturated fatty acids in the total polyunsaturated fatty acids of the brain phospholipids. These results suggest that in SAMR1 mice, the dietary alpha-linolenate/linoleate balance affects the (n-6)/(n-3) ratio of brain phospholipids, and this may modify emotional reactivity and learning ability.  (+info)

  • processes
  • Accelerated aging is testing that uses aggravated conditions of heat, humidity, oxygen, sunlight, vibration, etc. to speed up the normal aging processes of items. (
  • In the 1950s, researchers began to question the validity of accelerated aging tests which relied on dry heat and a single temperature, pointing out that relative humidity affects the chemical processes which produce paper degradation and that the reactions which cause degradation have different activation energies. (
  • This is especially true in processes such as the making of blue cheese or aged beef. (
  • Alzheimer's
  • The website of this NIH agency includes publications for consumers, information on Alzheimer's disease, clinical trials, and organizations related to aging. (
  • Age is a major risk factor for most common neurodegenerative diseases, including mild cognitive impairment, Alzheimer's disease, cerebrovascular disease, Parkinson's disease and Lou Gehrig's disease. (
  • peer-reviewe
  • Aging Cell is a peer-reviewed scientific journal and an official journal of the Anatomical Society. (
  • Psychology and Aging is a monthly peer-reviewed scientific journal published by the American Psychological Association. (
  • Healthy Aging
  • The Healthy Aging Program serves as the focal point at CDC for efforts to promote the health and quality of life of older Americans. (
  • Other priority health areas for the Healthy Aging Program include or have addressed the use of clinical preventive services, emergency preparedness, caregiving, mobility, multiple chronic conditions, quality of life, and advance care planning. (
  • This page is devoted to reviewing the changes associated with healthy aging. (
  • refers
  • In software engineering, software aging refers to all software's tendency to fail, or cause a system failure after running continuously for a certain time. (
  • Successful aging (American English) or successful ageing (British English) refers to physical, mental and social well-being in older age. (
  • Productive aging refers to activities which older people engage in on a daily basis. (
  • accelerate
  • Physical testing or chemical testing is carried out by subjecting the product to representative levels of stress for long time periods, unusually high levels of stress used to accelerate the effects of natural aging, or levels of stress that intentionally force failures (for further analysis). (
  • Elderly
  • An aging offender or an elderly offender in an individual over the age of 55 who breaks the law or is in prison. (
  • The US National Institute of Corrections identified a number of issues relating to an aging prison population structure, including both physical and mental health, death, nutritional problems, the social and emotional needs of elderly inmates, and the need to recognise differences between normal aging and aging accelerated by being in prison. (
  • Health care is identified as a paramount concern, because in many countries elderly inmates do not qualify for state funded healthcare, with the US National Institute of Corrections identifying that inmates over 60 cost three times more than those of a younger age to house in prison. (
  • It has also been found that the width of sulcus not only increases with age, but also with cognitive decline in the elderly. (
  • research
  • Since its founding in 1974, NIA research has changed the way America understands aging. (
  • RAND research on population and aging analyzes demographic and immigration trends and explores a range of issues, from family planning to religion to discrimination. (
  • It was established in 2002 and the editors-in-chief are Peter Adams (University of Glasgow), Adam Antebi (Max Planck Institute for Biology of Ageing), Ana Maria Cuervo (Albert Einstein College of Medicine), Brian Kennedy (Buck Institute for Research on Aging), and John Sedivy (Brown University). (
  • Research on successful aging, however, acknowledges the fact that there is a growing number of older adults functioning at a high level and contributing to the society. (
  • younger
  • A recent study found that TV hours among school-aged children have decreased in the past decade for children younger than 8 years. (
  • Physical weakness or mental fragility in relation to younger inmates, and the fact that offenders are cut off from their families can also have a great impact on aging offenders. (
  • researchers
  • This led researchers like Baer and Lindström to advocate accelerated aging techniques using the Arrhenius equation and a realistic relative humidity. (
  • Some researchers in aging studies are critical of the very term "successful aging" as it implies failure on the part of those who do not meet arbitrary criteria derived from neoliberal and/or biomedical definitions. (
  • person's
  • The United States Citizenship and Immigration Services defines an "aging out" case as, "a situation referring to a person's petition to become a permanent legal resident as a child, and in the time that passes during the processing of the application, the child turns 18 and ages out. (
  • Increases
  • In addition, the secondary esophageal peristalsis, which constitute a major clearence mechanism for refluxed gastric acid, seems to be evoked less frequently and less consistently, this increases the liklyhood of the occurrence of gastroesophageal reflux with age. (
  • This is mainly a result of general views of criminologists that age has no impact on offending, and that offenders tail off as age increases. (
  • prevent
  • Enhance the integration of efforts by the public health and aging services networks to promote health and prevent disease among older adults. (
  • We can't prevent aging, but we can understand its causes, take steps to limit its effects, temporarily reverse some of the damage it has caused, and prepare for the day when the software is no longer viable. (
  • cuts
  • Subprimal cuts can be dry aged on racks either in specially climate-controlled coolers or within a moisture-permeable drybag. (
  • years
  • This policy statement focuses on children and adolescents 5 through 18 years of age. (
  • 1 However, among children aged 8 years and older, average daily TV time remains over 2 hours per day. (
  • During the age work, she tells some years that bob and legally lee sold their consultation to paul, prompting the levitra to attack them. (
  • Sue and Gigi started an anti-aging beauty blog about 3 years ago then dropped it.Many friends and followers talked us into starting up again, hence, (
  • According to Scopus/Scimago Journal Rank (2015), Aging is ranked number 3 on Cites/Docs (2 years) in the Aging category. (
  • In 1929, a frequently used method in which 72 hours at 100 degrees Celsius is considered equivalent to 18-25 years of natural aging was established by R. H. Rasch. (
  • Aging (American English) or ageing (British English), in the context of food or beverages, is the leaving of a product over an extended period of time (often months or years) to aid in improving the flavor of the product. (
  • Traditional Balsamic Vinegar is aged for years in a succession of oak barrels to extract and concentrate flavors. (
  • gene
  • Thomas Johnson later showed that life extension of up to 65% was due to the mutation itself rather than due to calorie restriction, and he named the gene age-1 in the expectation that other genes that control aging would be found. (
  • The age-1 gene encodes the catalytic subunit of class-I phosphatidylinositol 3-kinase (PI3K). (
  • A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility" (PDF). (
  • flavor
  • The genus Thamnidium, in particular, is known to produce collagenolytic enzymes which greatly contribute to the tenderness and flavor of dry-aged meat. (
  • When dry aging using a moisture permeable material, surface mold growth is not present, flavor and scent exchange within the refrigerated environment is not a concern, and trim loss of the outer hardened surface is measurably reduced. (
  • In the case of beverages, such as the aging of wine, beer, or whiskey, storing the beverage for extended periods of time in wooden casks allows the liquid to extract flavor compounds from the wood itself, adding to the complexity and depth of flavor. (
  • found
  • However, some of the systems have a large reserve capacity, therefore, no major changes attributed to aging leading to major medical conditions are found in them. (
  • Changes in the gastrointestinal motility which are due to aging are found in the esophagus, stomach, small intestine, colon and in the anorectal region. (
  • Studies which incorporated the perspectives of older adults into the model of successful aging found that optimism, effective coping styles, and social and community involvement are more important to aging successfully than traditional measures of health and wellness. (
  • CT scans have found that the cerebral ventricles expand as a function of age. (
  • has noted that there is a decrease in grey matter volume between adulthood and old age, whereas white matter volume was found to increase from age 19-40, and decline after this age. (
  • Certain language functions such as word retrieval and production were found to be located to more anterior language cortices, and deteriorate as a function of age. (
  • suggests
  • The 'Wear and Tear' theory of aging suggests that our health deteriorates due to usage and other external factors, similar to how the value of machinery depreciates. (
  • cognitive
  • To successfully age, a person must retain sufficient cognitive abilities, which include not only neuropsychological domains, such as memory and executive function, but also must retain cognitive schemas. (
  • It has been suggested that age-related cognitive decline is due in part not to neuronal death but to synaptic alterations. (
  • There is converging evidence from cognitive neuroscientists around the world that age-induced cognitive deficits may not be due to neuronal loss or cell death, but rather may be the result of small region-specific changes to the morphology of neurons. (
  • Resistance
  • Furthermore, due to the increased resistance to flow across the upper esophageal sphincter caused by the loss of compliance with age, there is an increase in the pharngeal contraction pressures as well as the pharngeoesophageal wave velocity. (
  • adults
  • After making it through the maelstrom of middle age, many adults find themselves approaching older age wondering "what will give purpose to my life? (
  • Located within CDC's National Center for Chronic Disease Prevention and Health Promotion, the Program focuses primarily on adults age 50 or older. (
  • Eldercare Locator is a service by the U.S. Administration on Aging to help users find resources for older adults. (
  • One example of productive aging is retirement which moves older adults from paid forms of productivity to nonpaid activities. (
  • Studies using Voxel-based morphometry have identified areas such as the insula and superior parietal gyri as being especially vulnerable to age-related losses in grey matter of older adults. (
  • distinct
  • Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. (
  • Brain
  • The different functions of different tissues in the brain may be more or less susceptible to age-induced changes. (
  • Due to the complexity of the brain, with all of its structures and functions, it is logical to assume that some areas would be more vulnerable to aging than others. (
  • Health
  • This comprehensive guide provides information on various health and lifestyle subjects associated with aging and old age. (
  • The AOA has information for health professionals, caregivers, and for elders and families on a variety of aging-related topics. (
  • It includes information on the field of geriatrics as well as links to a physician finder tool and information on aging-related health topics. (
  • This is a service that helps find programs for people ages 55 and over that may pay for some of their costs of prescription drugs, health care, utilities, food, and other essential items or services. (
  • This CDC website has information on a variety of health and aging-related topics, including emergency preparedness, preventive care, advance care planning, chronic disease management, and more. (
  • This site for consumers from the National Library of Medicine includes information on senior health and links to other MedlinePlus pages on aging-related topics. (
  • This website from the National Institutes of Health presents aging-related health information for consumers on topics such as cancer, memory and mental health, vision and hearing, and many more. (
  • In 1970, Title X of the Public Health Service Act started providing for the federal family planning program, designed to provide resources for health services and counseling to low-income or uninsured individuals who may otherwise lack access to health care, including young people aging out of foster care. (
  • In 1999, President Clinton signed the Foster Care Independence Act, which doubled federal funding for independent living programs and provides funding for drug abuse prevention and health insurance for former foster care youth until age 21. (
  • mainly
  • This essay deals mainly with physiological but not extensively the structural changes that take place in the gastrointestinal system with aging. (
  • decline
  • Consequently, in the past most of the scientists have been focusing on negative aspects of aging or preventing the decline of youth. (
  • complexity
  • In widely used and specialized software, a common action to clear a problem is rebooting because aging occurs due to the complexity of software which is never free of errors. (
  • psychological
  • Along with physical changes, there are several psychological and social challenges to be dealt with, as we age. (
  • When the concept of aging is approached from a psychological and social perspective, three psychosocial theories emerge. (
  • people
  • What else did people in the Middle Ages know about gravity? (
  • I have read that in the Middle Ages people believed that angels pushed the Moon in its orbit, the angelic push presumably being in a tangential direction as per the Aristotelian belief that a force is needed to push an object in its direction of motion. (
  • Noteworthy people who had the surgery included Harold McCormick, chairman of the board of International Harvester Company, and the aging premier of Turkey. (
  • The Derek Zoolander Center for People Who Don't Age Good (DZCFPWDAG), a state-of-the-art, anti-aging center in New York City opens today at 4 pm. (
  • It reflects changing view on aging in Western countries, where a stigma associated with old age (see ageism) has led to considering older people as a burden on society. (
  • In two recent studies the vast majority of older people rated themselves as aging successfully, even when they did not meet all objective physical and mental criteria for successful aging. (
  • The United States Department of Housing and Urban Development's Family Unification Program, or FUP, provides Housing Choice Vouchers to young people aging out of the foster care system. (
  • The Administration for Children's Services, or ACS, and the federal Office of Housing Policy and Development, in cooperation with the New York City Housing Authority, has a Section 8 Priority Code for young people aging out of the foster care system. (
  • Older Women
  • Rosemary Leonard: The Potential for Empowerment from a Life-course Approach - Rosemary Leonard: The Role of Formal Organizations in the Empowerment of Older Women - Jenny Onyx: Reflections on Death / A Celebration of Aging. (
  • priority
  • Aging is used to gradually increase the priority of a task, based on its waiting time in the ready queue. (
  • Aging is used to ensure that jobs with lower priority will eventually complete their execution. (
  • However
  • However, as a criminal ages the type of crime can evolve, with crimes such as embezzlement, fraud, gambling and drunkenness either being unlimited by age or peaking when a criminal is of the age of 50 or above. (
  • take
  • Dry-aging can take from 15 to 28 days, and typically up to a third or more of the weight is lost as moisture. (
  • Women
  • Beth goes to effect see felicia in man where her doctor berates her for being still sexual also to not get the play on time and age to buy viagra that beth is free to her, telling the women to remove her company from the medication vitamin. (
  • Aging in women differs from men in more than one ways. (
  • This website has information on annual exams for women, including needed screening tests, evaluations, counseling, and immunizations based on age and risk factors, and includes links to College guidelines. (
  • The book features profiles of 12 women aged 85-105, all visual and performing artists actively engaged in the arts. (
  • Illustrated with 100+ photos of the lives of the San Francisco Bay Area women, the book challenges stereotypical perceptions and expectations, and documents that old age can be gratifying and filled with creative expression. (
  • time
  • Aging can be defined as the physical and mental changes that occur with the passage of time. (
  • It is popular with producers, wholesalers and retailers because it takes less time: typically only a few days and there is no moisture loss, so any given piece of meat sold by weight will have a higher value than a dry aged piece where moisture loss is desired for taste at the expense of final weight. (
  • medical
  • As a medical esthetician, and someone who has grown up in the beauty industry, anti-aging almost seems to be built into my DNA. (
  • Drugs & Aging is a monthly peer-reviewed medical journal published by Springer Science + Business Media under their Adis International imprint. (
  • A total of 13% was calculated for 2010, with Utah also concluding that medical care would be the most costly problem of the aging prison structure. (
  • human
  • The Baltimore Longitudinal Study of Aging is America's longest-running scientific study of human aging. (
  • study
  • Life extension strategies often study the causes of aging and try to oppose those causes in order to slow aging. (
  • It is the official journal of the International Society for the Study of the Aging Male and is published by Taylor and Francis Group. (
  • describe
  • Aging out is American popular culture vernacular used to describe anytime a youth leaves a formal system of care designed to provide services below a certain age level. (
  • services
  • This website has a section for consumers, which includes a directory of homes and services, and other information on aging services. (
  • Less
  • As we age, the skin becomes less elastic due to the decreased production of collagen. (
  • natural
  • The key effect of dry aging is the concentration and saturation of the natural flavour, as well as the tenderization of the meat texture. (
  • traditional
  • Often used to highlight the problems traditional foster care approaches face, aging out affects foster youth in a variety of ways. (
  • view
  • But on the other side of the coin, I also understand that many, if not most, view anti-aging practices as a chore. (
  • From both an academic and industrial point of view, the software aging phenomenon has increased. (
  • Ending Aging: Another Re-view, a Different View" (PDF). (