The mechanism of proteolysis by the β subunits of the 20S core particle is through a threonine-dependent nucleophilic attack. ... Which of these processes is the rate-limiting step in the overall proteolysis reaction depends on the specific substrate; for ... The proteasomal activation of NF-κB by processing p105 into p50 via internal proteolysis is one major example. Some proteins ... Each catalytic β subunit also possesses a conserved lysine residue required for proteolysis. Although the proteasome normally ...
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Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations, Cell, 2010;141: ...
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A yeast Ubc9 mutant protein with temperature-sensitive in vivo function is subject to conditional proteolysis by a ubiquitin- ...
Conjugation of proteins with multiple chains of the polypeptide of ATP-dependent proteolysis ». Proc. Natl. Acad. Sci. USA 77, ...
Proteolysis in Blue-Veined Cheese: An Intervarietal Study », Irish Journal of Agricultural and Food Research, vol. 36, no 2,‎ ...