Protéasome
The mechanism of proteolysis by the β subunits of the 20S core particle is through a threonine-dependent nucleophilic attack. ... Which of these processes is the rate-limiting step in the overall proteolysis reaction depends on the specific substrate; for ... The proteasomal activation of NF-κB by processing p105 into p50 via internal proteolysis is one major example. Some proteins ... Each catalytic β subunit also possesses a conserved lysine residue required for proteolysis. Although the proteasome normally ...
Patrick Mehlen
Cancer, 2011 Mehlen et al., « The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis. », Nature ... The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis. », Nature, 1998 Thibert et al., « ...
Cachexie cancéreuse
40, 2002, p. 929-936 (DOI 10.1055/s-2002-35411) (en) B. M. Wieland, « Is there a human homologue to the murine proteolysis- ... 84, 2001, p. 1599-1601 (PMID 11401311) (en) P. T. Todorov et al., « Role of a proteolysis-inducing factor (PIF) in cachexia ... 22, 2004, p. 866-870 (PMID 15641484) (en) R. Cabal-Manzano et al., « Proteolysis-inducing factor is expressed in tumours of ... 80, 1999, p. 1734-1737 (PMID 10468289) (en) S. M. Wyke et M. J. Tisdale, « NF-kappaB mediates proteolysis inducing factor ...
André Sentenac
1985) 18: 31-90 Marzouki, N., CaMier, S., Ruet, A, Moenne, A, and Sentenac, A. Selective proteolysis defines two DNA binding ... Biol., (1998), 63, p. 381-389 Marzouki, N., et al., « Selective proteolysis defines two DNA binding domains in yeast ...
Préséniline 1
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations », Cell, no 7, ...
Manjula Reddy
avec Singh, Santosh Kumar et a., Regulated proteolysis of a cross-link-specific peptidoglycan hydrolase contributes to ... Regulated proteolysis of a cross-link-specific peptidoglycan hydrolase contributes to bacterial morphogenesis », Proceedings of ...
Mucus
Properties of gastric and duodenal mucus: effect of proteolysis, disulfide reduction, bile, acid, ethanol, and hypertonicity on ...
Ubiquitine
Une nouvelle technologie, appelée PROTAC pour PRoteolysis-TArgeting Chimeras, permet de détourner et d'utiliser ce système ...
Ubiquitination
Réparation de l'ADN (PCNA, etc.). Une nouvelle technologie, appelée PROTAC pour PRoteolysis-TArgeting Chimeras, permet de ...
Rétrécissement aortique
H. M. Tsai, I. I. Sussman et R. L. Nagel, « Shear stress enhances the proteolysis of von Willebrand factor in normal plasma », ...
KLK5
387, no 6, juin 2006, p. 635-824 (PMID 16800723, DOI 10.1515/BC.2006.081, S2CID 83910246) « Kallikrein-mediated proteolysis ...
Lactobacillus plantarum
82, no 2, 2003 C.N. Lane, « Contribution of starter and adjunct lactobacilli to proteolysis in Cheddar cheese during ripening ... Proteolysis during ripening of miniature washed-curd cheeses manufactured with different strains of starter bacteria and a ...
JUNQ et IPOD
A yeast Ubc9 mutant protein with temperature-sensitive in vivo function is subject to conditional proteolysis by a ubiquitin- ...
PROTAC
Les PROTACs (proteolysis-targeting chimeras) sont de petites molécules bi-bifonctionnelles, conçues pour induire la dégradation ...
Aaron Ciechanover
Conjugation of proteins with multiple chains of the polypeptide of ATP-dependent proteolysis ». Proc. Natl. Acad. Sci. USA 77, ...
Danablu
Proteolysis in Blue-Veined Cheese: An Intervarietal Study », Irish Journal of Agricultural and Food Research, vol. 36, no 2, ...
Botulisme
Alpha-Latrotoxin Rescues SNAP-25 from BoNT/A-Mediated Proteolysis in Embryonic Stem Cell-Derived Neurons », Toxins, vol. 3, no ...
Maladie de Willebrand
Shear stress enhances the proteolysis of von Willebrand factor in normal plasma », Blood, no 83, 1994, p. 2171-2179 (lire en ...