• Malignant pleural mesothelioma is characterized by numerous molecular alterations at the chromosomal, genetic and epigenetic levels. (inserm.fr)
  • Just like the sequence may vary through a mutation, the gene activity level may change through an « epimutation » (an epigenetic modification) which is heritable and does not entail any concomitant genetic alteration. (medecinesciences.org)
  • Tradition opposes the genetic and epigenetic visions, the latter being often adequated to the DNA methylation phenomenon. (medecinesciences.org)
  • A group of rare diseases is produced by a genetic defect of vitamin B12 cellular metabolism. (academie-medecine.fr)