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  • Drug
  • Fifteen women had been taking lamivudine 150 mg twice daily for 53 to 182 days as part of a drug combination that included either abacavir and zidovudine or lopinavir, ritonavir, and zidovudine. (cnil.info)
  • infection
  • Zidovudine can weaken your immune system and cause signs of infection (fever, mouth sores, skin sores, flu symptoms, pale skin). (peacehealth.org)
  • In vitro sensitivity results vary greatly depending upon the time between virus infection and zidovudine treatment of cell cultures, the particular assay used, the cell type employed, and the laboratory performing the test. (sidasante.com)
  • Partial inhibition of viral activity in cells with chronic HIV infection (presumed to carry integrated HIV DNA) required concentrations of zidovudine (8.8 µg/ml in one laboratory to 13.3 µg/ml in another) which are approximately 100 times as high as those necessary to block HIV replication in acutely infected cells. (sidasante.com)
  • Hepatic
  • More serious and potentially life-threatening adverse effects reported include lactic acidosis with hepatic steatosis, but this rare adverse event is mostly associated with Zidovudine. (wikipedia.org)
  • hepatitis
  • HIV-positive patients with chronic hepatitis B virus (HBV) infections are at risk for potential flares of hepatitis that can occur with abrupt discontinuation of Lamividine/zidovudine because Lamivudine is also used in low doses for treatment against active HBV. (wikipedia.org)
  • neutropenia
  • The most common adverse effects of Lamividine/zidovudine are similar to other NRTI's and includes headache, neutropenia, anemia, nausea, vomiting, myopathy and nail pigmentation. (wikipedia.org)
  • The combination of zidovudine with paracetamol can increase the risk of neutropenia. (wikipedia.org)
  • incorporation
  • The incorporation of zidovudine-triphosphate into the proviral DNA chain blocks further chain formation and results in chain termination. (intekom.com)
  • Studies in cell culture suggest that zidovudine incorporation by cellular alpha-DNA polymerase may occur, but only to a very small extent and not in all test systems. (sidasante.com)
  • CAPSULE
  • Each capsule contains 100 mg of zidovudine and the inactive ingredients corn starch, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate. (sidasante.com)
  • Pregnancy
  • Zidovudine is also given during pregnancy to prevent an HIV-infected woman from passing the virus to her baby. (peacehealth.org)
  • The safety of ASPEN ZIDOVUDINE 100 MG and ASPEN ZIDOVUDINE 250 MG for the mother and foetus during the first trimester of pregnancy has not been established. (intekom.com)
  • Pregnant women considering the use of ASPEN ZIDOVUDINE 100 MG and ASPEN ZIDOVUDINE 250 MG during pregnancy for prevention of HIV transmission to their infants should be advised that transmission might still occur despite therapy. (intekom.com)
  • Lamividine/zidovudine is pregnancy category C in the United States, meaning there are potential risks to the baby during pregnancy, but potential benefits may outweigh the risks. (wikipedia.org)