Yeast genes mating type fungal. Medical search. Frequent questions

We already know that a much more famous type of yeast, Saccharomyces cerevisiae (this is the yeast used in baking, winemaking, and brewing) will very occasionally mate with each other - particularly when undergoing stressful conditions. (sciencealert.com)
Saccharomyces cerevisiae and its closely related yeasts undergo mating type switching by replacing DNA sequences at the active mating type locus (MAT) with one of two silent mating type cassettes. (elsevierpure.com)
Throughout history, the yeast Saccharomyces cerevisiae has played a central role in human society due to its use in food production and more recently as a major industrial and model microorganism, because of the many genetic and genomic tools available to probe its biology. (asm.org)
However, major genetic engineering limitations have kept this yeast from replacing the commonly used yeast Saccharomyces cerevisiae in industrial applications. (asm.org)
The yeast Saccharomyces cerevisiae has served as the major eukaryotic organism for synthetic biology, but lacks the metabolic potential that could be exploited in many of the more than one thousand yeast species that have been identified to date. (asm.org)
A Genetic Screen To Identify Genes Influencing the Secondary Redox Couple NADPH/NADP+ in the Yeast Saccharomyces cerevisiae. (harvard.edu)
A Candida albicans gene (CPH1) was cloned that encodes a protein homologous to Saccharomyces cerevisiae Ste12p, a transcription factor that is the target of the pheromone response mitogen-activated protein kinase cascade. (embl-heidelberg.de)
BLAST search for sequence similarity within fungal genomes, provided by the Saccharomyces Genome Database. (candidagenome.org)

The team didn't catch C. auris in the act, but they were able to analyze the fungal and mitochondrial genes in 1,285 strains of fungus. (sciencealert.com)
Through the sexual reproduction of P. chrysogenum, the researchers have produced fungal strains with new properties that are quite relevant biotechnologically- an example of this being high penicillin production that lacks the contaminant chrysogenin. (xantana.com)
In the experiment, Dyer and his colleagues paired strains with compatible mating genes and grew them with different light and food conditions. (xantana.com)
The SWI5 gene product was overproduced in yeast from the GAL1-10 promoter, since the SWI5 protein is made at very low levels in wild-type strains, and protein extracts were used to demonstrate that the SWI5 protein binds in vitro to a segment of the HO promoter required for transcriptional activation in vivo. (ox.ac.uk)
By breeding two of these mating-type engineered K. marxianus strains, we combined three complex traits-thermotolerance, lipid production, and facile transformation with exogenous DNA-into a single host. (asm.org)
A comparative genomic analysis supported the high quality of the F. equiseti assembly, exhibiting good collinearity with the reference strains, 3,483 species-specific genes, and 1,805 core genes. (researchsquare.com)
Our being identified by conventional methods data show that some of the fluconazole-resistant strains have all the strains were frozen and maintained in the diverse mechanisms of resistance, including the presence of yeast stock collection of the Laboratorio Especial de Mico- point mutations in the ERG11 gene and overexpression of logia-UNIFESP for different periods of time. (pdftreatment.com)
By sequencing the targeted genome area or the complete genome, these two methods help scientists exploring the fungal community, discovering strains of industrial interest, curing diseases, developing biotechnological tools, and more. (cd-genomics.com)
Procedures for identifying types and strains of fungi. (lookformedical.com)
Candida albicans strains without a functional CPH1 gene (cph1/cph1) show suppressed hyphal formation on solid medium. (embl-heidelberg.de)

Critical interpretations of fossil fungi combined with phylogenies of living species have the potential to reveal patterns of character evolution and to inform estimates of the geological timing of fungal radiations. (ubc.ca)
Some of the best fungal fossils are of thyriothecia, formed by fly-speck fungi. (ubc.ca)
However, because it reflects a common pattern seen in the best sampled fungi and in narrower studies of genera and families, I hypothesize that regional endemism is the general pattern in well-studied genera and more generally fungal biogeography. (ubc.ca)
These analyses have also helped identify genes that were differentially expressed in DED fungi grown under defined experimental conditions. (sisef.it)
Until recently, however, functional analysis of the DED fungi was hampered by the lack of protocols for efficient gene knockout and by the unavailability of a full genome sequence. (sisef.it)
Fungi ITS sequencing and fungal whole-genome sequencing are two of the main technologies used in modern mycology studies. (cd-genomics.com)
By systematically analyzing 304 genomes from all major fungal groups, together with a broad range of eukaryotic outgroups, we have identified 188 novel orthogroups associated with major changes during the evolution of fungi. (biomedcentral.com)
The overall picture is one of a relatively small number of novel genes appearing at major evolutionary transitions in the phylogeny of fungi, with most arising de novo and horizontal gene transfer providing only a small additional source of evolutionary novelty. (biomedcentral.com)
Our findings contribute to an increasingly detailed portrait of the gene families that define fungal phyla and underpin core features of extant fungi. (biomedcentral.com)
A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. (lookformedical.com)
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in fungi. (lookformedical.com)
The MAT (MAting Type) locus and other sex-related genes were recognized in all 23 black fungi. (nau.edu)
The genomic synteny of the MAT-locus flanking genes (SLA2-APN2-COX13) is not conserved in black fungi as is commonly observed in Eurotiomycetes, indicating a unique genomic context for MAT in those species. (nau.edu)
The heterokaryon (het) genes expansion associated with the low selective pressure at the MAT-locus suggests that a parasexual cycle may play an important role in generating diversity among those fungi. (nau.edu)
A new paper from Duke molecular genetics and microbiology shows how pathogenic Cryptococcus fungi evolved from having many sexes to just two through 50 million years of gene swapping. (phys.org)
Although there are various species of bacteria, filamentous fungi and other yeast species that are naturally capable of efficiently metabolizing D-xylose, they lack the other crucial advantages of the yeast S. cerevisiae , which have made it the most prominent industrial microorganism. (biomedcentral.com)
Weather and climate changes may be affecting these types of fungi. (cdc.gov)
Generate new information about fungal diseases and disease-causing fungi. (cdc.gov)

The discovery through the genome sequence of C. albicans mating type locus and the delineation of the unique pathway of a parasexual cycle are discussed. (cdc.gov)
The mating type of yeast is determined by the allele, either a or alpha, at the MAT locus. (ox.ac.uk)
We found that co-presence of mating type a1 and α2 genes was sufficient to prevent mating type switching, suggesting that ploidy information resides solely in the mating type locus. (elsevierpure.com)
Its mating type locus (MAT) contains more than 20 genes. (doe.gov)
Click "Gene Ontology Details" to view all GO information and evidence for this locus as well as biological processes it shares with other genes. (yeastgenome.org)
At one location or locus known as P/R, genes encode pheromones and pheromone receptors that help the fungus recognize compatible mating types. (phys.org)
At the other locus, called HD, genes govern the development of sexual structures and reproductive spores. (phys.org)
Multi Locus Sequence Typing (MLST) schemes and isolate databases for C. albicans , C. glabrata , C. krusei , and C. tropicalis are available from PubMLST.org The website offers tools for strain typing and epidemiology, as well as extensive, manually curated isolate databases. (candidagenome.org)

The yeast pheromone pathway has been extensively characterized, and is an ideal system for studying transcriptional regulation. (nih.gov)
To dissect the epigenetic regulation of GLS pathogenesis, we characterized a histone deacetylase gene Cfhos2 in Colletotrichum fructicola , the causing agent of GLS. (biomedcentral.com)
Fungal pathogenesis is a sophisticated process including infectious development of the pathogen and fungus-host interactions, which requires a fine-tuned regulation of gene expression dynamics. (biomedcentral.com)

The evolution of fungal species, shown by multilocus sequence typing, enabled construction of a phylogenetic tree of all known fungal pathogens with assignments to well-described families and orders. (cdc.gov)
In the fungal world, the number of sexes depends on the species. (xantana.com)
Cryptococcal disease is acquired via inhalation of haploid yeast or basidiospores from the environment.Genus Filobasidiella contains approximately 38 Cryptococcus species. (doe.gov)
One species, B. vulgaris, includes two 'types', G-type and P-type that differ in trichome density, and their glucosinolate and saponin profiles. (pacb.com)
CGMCC 1.7012(T)) is the type strain of the species Kosakonia oryzae and was isolated from surface-sterilized roots of the wild rice species Oryza latifolia grown in Guangdong, China. (pacb.com)
Between the two phyla, Basidiomycetes species may have thousands of (tetrapolar) mating types as well as a pheromone system. (tripod.com)
I delimited species in the mushroom genus Russula based on the fungal nuclear internal transcribed spacer 2 (ITS2) DNA barcode region. (ubc.ca)
In the case of DED, three fungal species are known to induce the disease. (sisef.it)
Candida albicans is an opportunistic pathogenic yeast It is one of the few species of the genus Candida that causes the human infection candidiasis, which results from an overgrowth of the fungus. (ensembl.org)
C. albicans is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. (ensembl.org)
A special type of medium is CHROMagar™ Candida which can be used to identify different species of candida. (ensembl.org)
Homologues, gene trees, and whole genome alignments across multiple species. (ensembl.org)
The species in this genus can be categorized into three groups depending on their type of trunk ( Olson and Rosell, 2006 ). (frontiersin.org)
General characteristics, phylogenomic relationships, transposable elements, sex-related genes, protein family evolution, genes related to protein degradation (MEROPS), carbohydrate-active enzymes (CAZymes), melanin synthesis and secondary metabolism were investigated and compared between species. (nau.edu)
All Capronia species are homothallic as both MAT1-1 and MAT1-2 genes were found in each single genome. (nau.edu)
Macrophomina phaseolina is one of the most destructive necrotrophic fungal pathogens that infect more than 500 plant species throughout the world. (biomedcentral.com)
To overcome the host plant defense response, M. phaseolina encodes a significant number of P450s, MFS type membrane transporters, glycosidases, transposases, and secondary metabolites in comparison to all sequenced ascomycete species. (biomedcentral.com)
The result was an organism with a bipolar mating system, much like the male and female sexes that embody most species. (phys.org)
PathoYeastract (Pathogenic Yeast Search for Transcriptional Regulators And Consensus Tracking) is a curated repository of all known regulatory associations between transcription factors (TF) and target genes in pathogenic Candida species, based on hundreds of bibliographic references. (candidagenome.org)

Genetic manipulations allowed analysis of changes in gene expression underlying pheromone signaling, cell cycle control, and polarized morphogenesis. (nih.gov)
Genetic analysis confirmed that genes had been sexually recombined. (xantana.com)
Genetic and molecular analyses have led to the identification, cloning and characterization of a few genes that contribute to parasitic fitness in the pathogens. (sisef.it)
Molecular genetics focuses on the structure and function of the genetic units, ie, the chemical composition of genes and their expression in determining the structure of proteins, the most important functional components of cells. (thecanadianencyclopedia.ca)
Population genetics analyses the pattern of distribution of genes in populations of organisms, and changes in the genetic structure of populations. (thecanadianencyclopedia.ca)
The effective use of family genes need a genetic markers: a-strain distinctive line of the fresh new types which includes numerous auxotrophic and you will opposition marker genes usually fulfill these standards. (bflybook.com)
An industrial yeast strain for bioethanol production with lignocellulose hydrolysates has been developed in the genetic background of a strain widely used for commercial bioethanol production. (biomedcentral.com)

Mating factor receptors STE2 and STE3 are integral membrane proteins that may be involved in the response to mating factors on the cell membrane. (wikipedia.org)
Deletion of the SOWgp gene by using a targeted gene replacement strategy resulted in partial loss of the ability of intact spherules to bind to ECM proteins and a significant reduction in virulence of the mutant strain. (kenyon.edu)
The FH1 domain is also a binding site for diverse SH3-domain containing proteins like Src-like non-receptor tyrosine kinases, WISH (WASP-interacting SH3 protein) and IRSp53 (insulin receptor substrate) in mammals, and Hof1p in yeast [ 6 ]. (biomedcentral.com)
Innovation of mitochondria-localized proteins occurred widely during fungal transitions, indicating their previously unrecognized importance. (biomedcentral.com)
Coupling of cell identity to signal response in yeast: interaction between the alpha 1 and STE12 proteins. (embl-heidelberg.de)

Unfortunately, this yeast - known as Candida auris - is a health menace, having now spread around the world and become resistant to multiple drugs. (sciencealert.com)
that causes oral, vaginal, and systemic infections Triazole drugs such as fluconazole and The frequency of life-threatening fungal infections is itraconazole are commonly used to treat Candida infections. (pdftreatment.com)
Accessibility and Contribution to Glucan Masking of Natural and Genetically Tagged Versions of Yeast Wall Protein 1 of Candida albicans. (montana.edu)

Transcriptional profiling using microarrays is a powerful tool for identifying genes expressed during mold-to-yeast morphogenesis and host-fungus interactions in infected tissue cultures and biofilms. (cdc.gov)
A complete sequence of its genome displayed that the fungus still carried the genes necessary for sexual reproduction. (xantana.com)
This is the first report of LPS-induced NO to regulate fungal secondary metabolite production, which provides new insights on the role of bacterial LPS in bacterium-fungus interactions and an effective strategy to enhance hypocrellin production. (bvsalud.org)
When haploid fungal spores germinate, their nuclei divide mitotically to produce hyphae (the structural unit of a fungus in its vegetative phase or mycelium). (tripod.com)
It is the only mushroom-forming fungus for which genes have been inactivated by homologous recombination. (nature.com)
It is generally referred to as a dimorphic fungus since it grows both as yeast and filamentous cells. (ensembl.org)
The correct taxonomic status of C. immitis as an ascomycete fungus was demonstrated by Ophuls and Moffit in 1900 (4) by culture on artificial of the fungal mycelia. (kenyon.edu)
Some members of Cryptococcus , a family of fungus linked to human disease, can have tens of thousands of different mating types. (phys.org)

Interest in a potential attenuated live vaccine has been stimulated by the finding that targeted disruption of the Blastomyces dermatitidis gene, which encodes the surface adhesin BAD-1, renders the mutant avirulent. (cdc.gov)
The yeast HO gene, which encodes an endonuclease involved in initiating mating type interconversion, is expressed in mother cells but not in daughters. (ox.ac.uk)
Comparative analyses of its 38.5-megabase genome, which encodes 13,210 predicted genes, reveal the species's unique wood-degrading machinery. (nature.com)

The assembly was characterized, including analyses of the genomic structure, with the aim of providing data to support the discovery of beneficial or harmful genes and to improve our understanding of the molecular pathogenesis. (researchsquare.com)
To our knowledge, yeast extract, 2% Bacto peptone, and 2% D-glucose, 2% this is the first assessment at molecular level of fluconazole resistance mechanisms in C. albicans isolates from SouthAmerica. (pdftreatment.com)
Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast. (harvard.edu)
GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies ( Molecular Function , Biological Process , and Cellular Component ), a reference, and an evidence code. (yeastgenome.org)
Today the molecular structure and function of genes is quite well understood. (thecanadianencyclopedia.ca)
Track the emergence and spread of fungal diseases by conducting molecular surveillance and genomic epidemiology. (cdc.gov)

Advance the use of genomics and metagenomics for detecting fungal pathogens and antifungal drug resistance. (cdc.gov)

Two other loci, HML and HMR, contain complete copies of the alpha and a genes, respectively, which are not expressed. (ox.ac.uk)
The four SIR gene products are required in trans for repression of the silent loci, as are cis-acting sites on either side of HML and HMR, about 1000 bp from the mating-type promoters. (ox.ac.uk)
Recently, a novel mode of mating type switching was reported in methylotrophic yeast, including Ogataea polymorpha, which utilizes chromosomal recombination between inverted-repeat sequences flanking two MAT loci. (elsevierpure.com)
Monokaryons that encounter each other fuse, and a fertile dikaryon forms when the alleles of the mating-type loci matA and matB of the partners differ. (nature.com)
Interestingly, all Brazilian fluconazole-resistant isolates showed homozygosity at mating-type loci ( MTL ) associated withfluconazole resistance. (pdftreatment.com)
MAT1-1 and MAT1-2 contain four or five genes more than are present in the MAT loci of most ascomycetes. (kenyon.edu)
Along with their cDNA structures, all genes in the MAT loci are transcribed (6) . (kenyon.edu)

The genes were selected on thorough literature review and on the basis of presence of more than one G-box (Binding motif of PTF1) in their promoter regions. (als-journal.com)

One-third of the 471 genes predicted to encode transcription factors are differentially expressed during sexual development of S. commune . (nature.com)
The genomic organization of the human genes that encode protein prenyltransferases is shown in Figure 1 . (biomedcentral.com)

The diploid genome size is approximately 29 Mb, and up to 70% of the protein coding genes have not yet been characterized. (ensembl.org)

Opportunistic fungal sepsis is seen most often in immunosuppressed patients with severe neutropenia or in postoperative patients with intravenous catheters and usually follows prolonged antibiotic therapy. (lookformedical.com)

In order to facilitate comparative fungal genomics a copy of this database was incorporated into MycoCosm. (doe.gov)

The ongoing annotation of these genomes should spark a new wave of interest in the DED pathosystem, as it should lead to the formal identification of genes modulating parasitic fitness. (sisef.it)
The bantiana-clade contained the highest number of predicted genes (12 817 on average) as well as larger genomes. (nau.edu)

Histone-modifying enzymes, which regulate eukaryotic chromatin conformation and gene expression, are key epigenetic factors controlling fungal development, virulence, and secondary metabolism. (biomedcentral.com)
Stress-induced changes of gene expression are crucial for survival of eukaryotic cells. (prolekarniky.cz)
The chromosomal locations and number of exons from protein prenyltransferase genes in the major eukaryotic model organisms are shown in Table 2 . (biomedcentral.com)

Taken together, we demonstrate that Cfhos2 is a key epigenetic factor regulating appressorium development, virulence gene expression, and GLS pathogenesis in C. fructicola . (biomedcentral.com)

Characterization of a transcription factor involved in mother cell specific transcription of the yeast HO gene. (ox.ac.uk)
The predicted amino acid sequence derived from the cloned SWI5 gene shows homology with the repeated DNA-binding domains ('zinc fingers') of Xenopus transcription factor TFIIIA. (ox.ac.uk)
Here we investigated the roles of transcription factors involved in yeast sexual development, such as mating type genes and the conserved zinc finger protein Rme1. (elsevierpure.com)
This entry include a group of fungal transcription factors, including Ste12, Cph1 and SteA. (embl-heidelberg.de)
STE12 is also required for transcription of alpha-specific genes, but there is no evidence that it binds directly to these genes. (embl-heidelberg.de)
The K. lactis STE12 protein did not cooperate with the S. cerevisiae alpha 1 protein to promote the overall mating process or the induction of transcription of an alpha-specific gene. (embl-heidelberg.de)
PTF1(Inorganic Phosphorus Starvation Induced Transcription Factor 1) is overexpressed during phosphorus stress and regulates number of genes to combat this abiotic stress. (als-journal.com)
PTF1 (Inorganic Phosphorus Starvation Induced Transcription Factor 1) is a member of bHLH (basic Helix Loop Helix) family of wheat regulating several genes during phosphorus starvation. (als-journal.com)
The primary function of the TFs (Transcription Factors) is to regulate gene expression by binding to cis -element. (als-journal.com)

Some bacteria carry tRNA genes encoding CCA termini, thus the CCA-adding enzyme is primarily involved in repairing damaged CCA ends in these organisms [9] . (prolekarniky.cz)

The mycelium which is made up of hyphae, the fruiting body, and the spores are the main characteristics of a fungal body. (cd-genomics.com)
Fungal replication requires spores. (cd-genomics.com)
Fungal spores produced by the fruiting body are haploid, indicating they only bear one chromosome for each gene (like human gametes). (cd-genomics.com)
Fungal spores are thinner than plant seeds and are lighter. (cd-genomics.com)

This genus typically reproduces asexually as haploid, encapsulated budding yeast, but may also be dispersed by means of sexually produced basidiospores. (doe.gov)

This enables us to identify candidate genes underlying glucosinolate diversity, trichome density, and study the genetics of biochemical variation for glucosinolate and saponins. (pacb.com)
www.thecanadianencyclopedia.ca/en/article/genetics. (thecanadianencyclopedia.ca)
Transmission genetics is concerned with identifying the genes that affect a particular characteristic, and also the patterns by which these genes are transmitted from generation to generation, or from cell to cell. (thecanadianencyclopedia.ca)

Curated mutant alleles for the specified gene, listed alphabetically. (yeastgenome.org)
Discontinuous variation often can be explained genetically by different forms of a gene called alleles: in an example from peas, Y is the allele for the yellow phenotype, and y for green. (thecanadianencyclopedia.ca)

Characterization of a "silencer" in yeast: a DNA sequence with properties opposite to those of a transcriptional enhancer. (ox.ac.uk)

These innovations include components for cell wall formation, functioning of the spindle pole body, polarisome formation, hyphal growth, and mating group signaling. (biomedcentral.com)

Analysis of the profiles specified by two different MAPKs-Fus3p and Kss1p-revealed functional overlap of the filamentous growth and mating responses. (nih.gov)
Unique features of these groups are that Basidiomycetes have more complex mating type systems consisting of much more polymorphic mating types and a pheromone/pheromone receptor system, and (filamentous) Ascomycetes have a somatic (heterokaryon) incompatibility system in addition to the sexual mating types. (tripod.com)
CPH1 complements both the mating defect of ste12 haploids and the filamentous growth defect of ste12/ste12 diploids. (embl-heidelberg.de)

All of these systems are primarily involved in prevention of matings between genetically similar individuals to avoid the harmful effects of inbreeding. (tripod.com)
Other yeasts that could solve many of these problems remain difficult to manipulate genetically. (asm.org)

They found that during evolution, a reshuffling of DNA known as translocation brought together separate chunks of sex-determining genes onto a single chromosome, essentially mimicking the human X or Y chromosome. (phys.org)
The chromosome diagrams and the locations of the genes on the cytogenetic map are according to the NCBI MapViewer [ 67 ]. (biomedcentral.com)

Genome-wide transcript profiling was used to monitor signal transduction during yeast pheromone response. (nih.gov)
As a broad host range pathogen, M. phaseolina possesses a large number of pathogen-host interaction genes including those for adhesion, signal transduction, cell wall breakdown, purine biosynthesis, and potent mycotoxin patulin. (biomedcentral.com)

In total, 13,134 functional genes were annotated, accounting for 94.97% of the total gene number. (researchsquare.com)
Our comprehensive analysis of the whole genome of F. equiseti provides basic data for studies of gene expression, regulatory and functional mechanisms, evolutionary processes, as well as disease prevention and control. (researchsquare.com)
However, there are few in-depth studies on the functional genes. (researchsquare.com)
Moreover, the traditional methods for functional gene discovery are insufficient to meet the modern-day research demands due to the high error rates and low efficiencies. (researchsquare.com)

Protein-coding and non-coding genes, splice variants, cDNA and protein sequences, non-coding RNAs. (ensembl.org)
Automatic comparisons of data from expressed sequence tags (ESTs) with genes (for example using the program Acembly, for which the results are available from the NCBI AceView server [ 2 ]) shows that all the human protein prenyltransferase genes have multiple alternative splice variants. (biomedcentral.com)

Ustilago maydis , a biotrophic fungal pathogen that infects maize plants, produces effectors that target hubs in the immune network of the host cell. (frontiersin.org)

In C. amylolentus , dozens of genes at two different locations on the chromosomes control what's called a tetrapolar, or four-part, mating system. (phys.org)

We demonstrate that one of these cis-acting sequences, HMRE, is able to switch off at least two nonmating-type promoters. (ox.ac.uk)
have analyzed the tef-1α sequences of F. equiseti , as well as the toxin-related genes PKS13 , PKS4, and TRI5 [26], and Kari has successfully cloned a protease gene [27]. (researchsquare.com)

Here, we engineered the thermotolerant yeast Kluyveromyces marxianus to create a new synthetic biology platform. (asm.org)
IMPORTANCE The yeast Kluyveromyces marxianus grows at high temperatures and on a wide range of carbon sources, making it a promising host for industrial biotechnology to produce renewable chemicals from plant biomass feedstocks. (asm.org)
To explore the role of STE12 in the pheromone induction of alpha-specific genes, we cloned STE12 and MAT alpha 1 homologs from the related yeast Kluyveromyces lactis. (embl-heidelberg.de)

Isolates were ERG11, and several genes encoding efflux pumps, as mea- maintained in solid yeast-peptone-glucose (YEPD: 1% sured by quantitative real-time RT-PCR. (pdftreatment.com)

Quantitative PCR and high-throughput methods, such as expressed sequence tag analysis, have been used for measuring gene expression and identifying subsets of elm genes that are differentially expressed in the presence of O. novo-ulmi . (sisef.it)

Genes, Fungal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)

The fungal incompatibility system regulates both sexual reproduction and somatic compatibility. (tripod.com)
RNA-seq based transcriptome analysis highlighted that Cfhos2 regulates secondary metabolism-related virulence genes during infection. (biomedcentral.com)

Transcriptome analysis revealed that NO mediated LPS-induced HA production via upregulating the expressions of critical genes associated with central carbon metabolism and downstream HA biosynthesis genes. (bvsalud.org)

Diagnostic subsets of coexpressed genes reflected signaling activity, cross talk, and overlap of multiple mitogen-activated protein kinase (MAPK) pathways. (nih.gov)

The latter is formed when diploid C. albicans cells mate when they are in the opaque form. (ensembl.org)
The genome of C. albicans strain WO-1, sequenced at the Broad Institute as part of the Fungal Genome Initiative (FGI). (candidagenome.org)

All cells must detect and respond to changes in their environment, often through changes in gene expression. (nih.gov)

These areas of the world often lack the laboratory infrastructure needed to diagnose fungal diseases, and limited availability of antifungal medications means that some patients may not have access to lifesaving treatments. (cdc.gov)
CDC is working with partners to improve access to fungal diagnostics and antifungal medications around the globe. (cdc.gov)

These mechanisms include the presence of point mutations in the ERG11 gene and overexpression of ERG11, andseveral genes encoding efflux pumps, as measured by quantitative real-time reverse transcriptase polymerase chain reaction. (pdftreatment.com)

We also describe the newly developed pipeline MycoSNP, a portable workflow for performing whole-genome sequencing analysis of fungal organisms including C. auris. (cdc.gov)

This resistance may be acquired through gene mutation. (lookformedical.com)

In this paper we describe the cloning and sequencing of the SWI5 gene. (ox.ac.uk)

While fungal sexual reproduction has several variants, all of them have the following three stages. (cd-genomics.com)

Here we report a draft genome sequence of the G-type, and re-sequencing of the P-type for comparison. (pacb.com)
Complete genome sequence of Kosakonia oryzae type strain Ola 51(T). (pacb.com)

So far, PTF1 from maize, soybean and rice [9-11] has been characterized regulating almost 450 genes involved in secondary root development and enhanced root hair surface area for improved phosphorus absorption [11,12]. (als-journal.com)

Some navigate a mating scene populated by thousands of sexes, while others clone themselves asexually. (xantana.com)
A schematic figure from the paper illustrates how recombination occurred at the centromere and then genes migrated and fused to leave Cryptococcus with just two sexes, when before it had many. (phys.org)

RNA polymerase II plays an active role in the formation of gene loops through the Rpb4 subunit. (harvard.edu)
the α subunit of FT and GGT1 is encoded by the same gene, FNTA (see Table 1 ). (biomedcentral.com)
Gene structures and chromosomal locations of human protein prenyltransferase subunit genes. (biomedcentral.com)

C. auris isn't your helpful bakers or brewer's yeast. (sciencealert.com)
Although we haven't seen the yeast in action, the idea that C. auris occasionally sexually reproduces is actually not as crazy as it sounds. (sciencealert.com)
Although there are lots more we need to know about C. auris , looking deep at its genes to discover a sex life is a good place to start. (sciencealert.com)

Fungal biologist Paul Dyer from the University of Nottingham had his suspicions about the mold's reproductive habits. (xantana.com)
In the 1960's, Japanese-American geneticist and evolutionary biologist Susumu Ohno proposed a theory in which the genes determining sex first arose at various spots scattered across the entire genome , but over time were "captured" on the sex chromosomes. (phys.org)

Furthermore, ecological preferences of Chaetothyriales were analysed, in conjuncture with the order-level phylogeny based on conserved ribosomal genes. (nau.edu)

Normally, yeast undergoes asexual reproduction through budding and splitting into daughter cells. (sciencealert.com)
Usually MAT-a and MAT-alpha cells are involved in mating. (doe.gov)
However same-sex mating between two MAT-alpha cells has also been observed. (doe.gov)
One common use is to avoid inbreeding by identifying individuals, cells or gametes as different from self (self-incompatibility as in mate choice, selective fertilization). (tripod.com)
Somatic cells form buds in yeast. (cd-genomics.com)
Cells maintain their internal homeostasis by adequate reprogramming of metabolic activities at all levels of gene expression, including chromatin remodeling, mRNA expression and degradation, translation and protein degradation. (prolekarniky.cz)

Gene coding regions of the tomato scaffold were predicted by FGENESH+ (http://linux1.softberry. (molquest.com)
The gene coding regions were predicted with FGENESH (http://linux1.softberry.com) and BLASTX (https://blast. (molquest.com)

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. (yeastgenome.org)
Individual genes can be identified through phenotypic inheritance patterns, but only if some variation is present in the phenotype. (thecanadianencyclopedia.ca)

In addition, the researchers discovered that the sex genes control the activities of biologically relevant genes-in this case the ones responsible for penicillin production. (xantana.com)

The team found some recombination, but most of it occurred before the yeast split into the five clades. (sciencealert.com)
Some clades have seemingly lost the ability to mate, while others have had limited recombination since the split. (sciencealert.com)
niger we have repeatedly located high proportions of recombination between your b i d and you can rysA marker genes into linkage class 111. (bflybook.com)

2022 ). Among all types of histone modifications, the reversible N-terminal lysine acetylation, regulated by histone acetyltransferase (HAT) and histone deacetylase (HDAC), is one of the best-characterized machineries (Kurdistani and Grunstein 2003 ). (biomedcentral.com)

Anatomy22

Organisms21

Diseases3

Chemicals and Drugs92

Analytical, Diagnostic and Therapeutic Techniques and Equipment27

Phenomena and Processes94

Disciplines and Occupations4

Technology, Industry, Agriculture2

Information Science7

Health Care4

Saccharomyces8

Strains10

Fungi18

Locus8

Regulation3

Species19

Genetic7

Proteins5

Candida3

Fungus8

Encodes3

Molecular6

Pathogens1

Loci7

Promoter Regions1

Encode2

Protein-codin1

Opportunistic1

Genomics1

Genomes2

Eukaryotic3

Pathogenesis1

Transcription9

TRNA genes1

Spores4

Haploid1

Genetics3

Alleles2

Characterization1

Hyphal1

Filamentous3

Genetically2

Chromosome2

Signal transduction2

Functional4

Splice variants2

Infects1

Tetrapolar1

Sequences2

Kluyveromyces3

Several genes1

Differentially expressed1

MeSH1

Regulates2

Biosynthesis1

Subsets1

Albicans2

Changes in gene expression1

Antifungal2

Mechanisms1

Organisms1

Resistance1

Cloning1

Variants1

Sequence2

Secondary1

Sexes2

Subunit3

Auris3

Biologist2

Phylogeny1

Cells6

Regions2

Phenotype2

Biologically1

Recombination3

20221