• In untreated, seropositive, Caucasian, college-educated men, with a mean age of 55, the prevalence of frailty, 3.4%, was similar to that of HIV seronegative males older than 65 from the same cohort [73]. (natap.org)
  • Prospective study over 25 years of a birth cohort initially studied at the age of 7. (bmj.com)
  • Objective: In the present study, we examined cohort differences in key components of psychosocial function, including subjective age, control beliefs, and perceived social integration, as indicated by loneliness and availability of very close others. (hu-berlin.de)
  • Methods: We compared data obtained 20 years apart in the Berlin Aging Study (in 1990-1993) and the Berlin Aging Study II (in 2013-2014) and identified case-matched cohort groups based on age, gender, cohort-normed education, and marital or partner status (n = 153 in each cohort, mean age = 75 years). (hu-berlin.de)
  • We discuss the possible role of sociocultural factors that might have led to the observed set of cohort differences. (hu-berlin.de)
  • The purpose of this analysis is to understand early changes in kidney function among a cohort of first-time sugarcane harvesters and to determine risk factors for kidney function decline. (cdc.gov)
  • Visual impairment as a risk factor of cognitive function impairment A six-year cohort study. (bvsalud.org)
  • We conducted a population -based cohort study , with a six-year follow-up period. (bvsalud.org)
  • Recently, researchers have successfully used machine-learning methods to derive a biomarker that is commonly referred to as predicted brain age (PBA) or brain age based on brain imaging data. (nature.com)
  • METHODS: Data were collected using the Spinal Alignment and Range of Motion Measure (SAROMM), the Gross Motor Function Classification System (GMFCS) and the Activity Scale for Kids (ASK). (uwo.ca)
  • Methods: Joint latent class mixed models were used to model sub-population kidney function trajectory over the course of 4 years (2012-2016). (cdc.gov)
  • We used data from the National Health Interview Survey from 1997 through 2010 to calculate the prevalence of these behaviors among older Americans and rank each state, and we analyzed overall trends in prevalence for each behavior over the 14 years. (cdc.gov)
  • Probability weighted logistic regression was used to determine personal health, community, and individual behavior risk factors associated with sub-population assignment. (cdc.gov)
  • MS can occur at any age but is mostly diagnosed in people aged 20 to 40 years old. (medicinenet.com)
  • Burden due to impaired kidney function was estimated in people aged 15 and over. (aihw.gov.au)
  • In people aged 65 years and over, the most burden due to impaired kidney function was from chronic kidney disease followed by coronary heart disease. (aihw.gov.au)
  • We calculated prevalence, standard errors (SEs), and 95% confidence intervals (CIs) and ranked states according to the prevalence of each risk factor indicator. (cdc.gov)
  • We analyzed trends by using weighted linear regression of prevalence on year. (cdc.gov)
  • The prevalence of smoking among US adults aged 65 years or older was 9.6% ( Table 1 ). (cdc.gov)
  • The prevalence of ED increases with age. (healthline.com)
  • In 2018, the prevalence rate of people with a disability of all ages in the United States was 12.6%, or 40,585,700 people. (medscape.com)
  • OBJECTIVE: To evaluate the prevalence of weight concerns and smoking for body weight reasons as a function of race and gender. (bmj.com)
  • This study was conducted to evaluate the prevalence of disability and its related factors among the elderly population in Kashan city, Islamic Republic of Iran. (who.int)
  • Chronic migraine prevalence, disability, and sociodemographic factors: results from the American Migraine Prevalence and Prevention Study. (nature.com)
  • Primary headache disorders in the Republic of Georgia Prevalence and risk factors. (nature.com)
  • Hence, the primary aim of this study was to estimate the prevalence of clinically relevant SD, in this context: impairments with associated distress, and to identify factors associated with SD among BCSs on AET. (aau.dk)
  • The present study examined a range of possible determinants of memory complaints, covering psychiatric and personality factors, medical history, cognitive test performance, and biological risk factors for dementia (APOE genotype, hippocampus and amygdala volumes, and white-matter hyperintensities). (nih.gov)
  • Increases in fluid cognitive performance over the last century are well documented and researchers have begun examining historical trends in personality and subjective well-being in old age. (hu-berlin.de)
  • To explore whether baseline visual impairment (VI) increases the risk of cognitive function impairment (CFI). (bvsalud.org)
  • The Mini-Mental State Examination (MMSE) was used to assess participants' cognitive function . (bvsalud.org)
  • Averagely, participants with VI experienced a decline in cognitive function 0.1 points faster per year than participants without VI, as measured by MMSE score. (bvsalud.org)
  • Background/objectives Obesity affects more than forty percent of adults over the age of sixty. (researchgate.net)
  • 18 years old) affects health of caregivers with mostly typically developing children versus children with a medical condition as a first step toward developing a screener to identify caregivers who need additional supports. (springer.com)
  • Central serous chorioretinopathy (CSCR) is a condition that affects central visual function. (health.mil)
  • This affects the functioning of the immune system. (medicinenet.com)
  • Over time, memory loss affects the ability to function at work or at home. (mayoclinic.org)
  • Both the obtained maximal level of FEV 1 and the rate of decline of FEV 1 determine the severity of lung function impairment at older age in symptomatic persons. (atsjournals.org)
  • Irrespective of the pathogenesis, it can lead to significant impairment of motor, sensory, or autonomic function. (medscape.com)
  • Older age, Black race, 10 years on ART, history of thymidine analog (TA), greater BMI, high waist circumference, hypertension and physical inactivity were associated with physical function impairment in univariate analyses (figure). (natap.org)
  • Black race, greater BMI and physical inactivity remained associated with physical function impairment in the multivariate model. (natap.org)
  • Modifiable risk factors for frailty including neurocognitive impairment, obesity, smoking, choice of initial cART (with NNRTI [non-nucleoside reverse transcriptase inhibitor]-based cART increasing risk of frailty), and level of education. (natap.org)
  • The purpose of this longitudinal study was to assess the factors in childhood that determine the level of FEV 1 in early adulthood in asthmatic individuals, and to examine factors associated with decline in FEV 1 during adulthood. (atsjournals.org)
  • A smaller decline in FEV 1 after ages 22 to 32 yr occurs in asthmatics who quit smoking and who continue to use inhaled corticosteroids. (atsjournals.org)
  • Many published epidemiologic studies on age-related growth and decline of lung function have as their primary aim the natural history of FEV 1 and FVC throughout childhood and adulthood in healthy subjects ( 1-9 ). (atsjournals.org)
  • These studies generally show that a growth in FEV 1 during childhood is followed by a stable phase from adolescence through early adulthood and a decline in FEV 1 after the age of 32 yr ( 4 , 5 ). (atsjournals.org)
  • Therefore, it is important to know which factors are associated with the level of FEV 1 in early adulthood and which factors are associated with an accelerated decline of FEV 1 throughout adulthood. (atsjournals.org)
  • Studies of risk factors for accelerated decline in FEV 1 have generally focused on the effect of smoking on lung function, and have involved subjects with chronic obstructive pulmonary disease (COPD) or subjects from the general population. (atsjournals.org)
  • Two longitudinal studies, one of middle-aged and older men with no history of asthma, the other of subjects aged 65 yr or older, found that bronchial hyperresponsiveness (BHR) and atopy were both independent predictors of decline of lung function ( 15 , 16 ). (atsjournals.org)
  • They are used to diagnose airways obstruction, assess its severity and prognosis, delineate risk factors ( e.g . pre-operative assessment), detect early lung disease, and monitor for normal lung growth and lung function decline. (ersjournals.com)
  • However, in this study, tests for dementia given to persons older than 30 years showed some performance decline from 40 to 45 years. (medscape.com)
  • AD is responsible for the sharp decline in survival in persons with DS older than 45 years. (medscape.com)
  • greater BMI and physical inactivity are important modifiable factors that may prevent further decline in physical function with aging. (natap.org)
  • BMD changes that occur with increasing age are thought to be related to the decline in osteoblastic (bone formation) function (Mahan & Escott-Stomp, 2004). (unm.edu)
  • Results: Of 181 new workers median age 19 years old (IQR: 4), 39 (22%) were identified as having non-stable kidney function with an annual age-adjusted decline of estimated glomerular filtration rate (eGFR) of -1.0 ml/min per 1.73 m2 (95% CI: -3.4, 1.3). (cdc.gov)
  • A better understanding of preexisting risk factors is needed to determine why individuals are entering the workforce with reduced kidney function and elevated blood pressure and increased risk of renal function decline. (cdc.gov)
  • Based on our findings, the occurrence of cancer is much higher in adults over 75 years of age compared with the proportion of patients in this age group who enroll in clinical trials," said lead study author Bindu Kanapuru, MD, medical officer in the Division of Hematology Products, Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research. (prnewswire.com)
  • With so few patients aged 75 or older enrolled in clinical trials, critical information on the safety and effectiveness of new therapies in this age group is greatly lacking. (prnewswire.com)
  • By contrast, patients aged 75 and older account for approximately 29 percent of CML diagnoses, yet this age group made up less than 4 percent of those enrolled in clinical trials to evaluate new treatments for the disease. (prnewswire.com)
  • We weren't surprised to see that, overall, adults aged 75 years and older were under-represented in clinical trials, as this is common across cancer trials," said Dr. Kanapuru. (prnewswire.com)
  • But Dr. Kanapuru points to multiple barriers to enrolling patients aged 75 and older in clinical trials. (prnewswire.com)
  • Recent clinical trials suggest that improving endothelial function in patients with HF concurrently leads to improvement of heart biomechanics [ 12 ]. (hindawi.com)
  • Hence, the current clinical trial sought to investigate the effect of supplemental lycopene tablets on some CVD risk factors such as lipid profile, blood pressure (BP), and flow-mediated dilation (FMD) as an index of endothelial function in Iranian HFrEF patients. (hindawi.com)
  • Epidemiology, and the findings should be factored into clinical decision making and program design for disease prevention, screening, and treatment. (who.int)
  • [ 3 ] (Jervis 1948) Further research has confirmed premature aging and clinical deterioration, and the presence of neuropathological changes in AD. (medscape.com)
  • Clinical differences have been observed, mainly in the early age of onset of AD in individuals with DS. (medscape.com)
  • Besides age, other studies have also shown some clinical differences that might be unique to persons with DS. (medscape.com)
  • The EU Clinical Trials Register currently displays 43692 clinical trials with a EudraCT protocol, of which 7246 are clinical trials conducted with subjects less than 18 years old. (clinicaltrialsregister.eu)
  • Those with memory complaints did not differ on any of the biological risk factors for dementia. (nih.gov)
  • Alzheimer disease (AD) is the most common progressive degenerative form of dementia, strongly associated with advancing age. (medscape.com)
  • Impaired kidney function was causally linked to 6 diseases-chronic kidney disease, coronary heart disease, dementia, stroke, gout and peripheral vascular disease (see ABDS 2018 Risk factor estimates data table ). (aihw.gov.au)
  • Impaired kidney function was responsible for the entire burden of chronic kidney disease, 12% of gout burden, 10% of peripheral vascular disease burden, 8% of dementia burden, and 6% of coronary heart disease and stroke burden. (aihw.gov.au)
  • The most important modifiable risk factors for chronic migraine include overuse of acute migraine medication, ineffective acute treatment, obesity, depression and stressful life events. (nature.com)
  • This article will review the categories of OP, how OP is measured, non-modifiable risk factors, modifiable risk factors, bone remodeling, exercise and bone health, and the relationship of diet and race to OP. (unm.edu)
  • What are the Non-modifiable Risk Factors Associated with Osteoporosis? (unm.edu)
  • 2001) have classified OP risk factors as non-modifiable and modifiable. (unm.edu)
  • What are the Modifiable Risk Factors Associated with Osteoporosis? (unm.edu)
  • Chronic migraine has a great detrimental influence on a patient's life, with a severe impact on socioeconomic functioning and quality of life. (nature.com)
  • On the basis of these findings, CDC recommends the 4-month regimen as a treatment option for U.S. patients aged ≥12 years with drug-susceptible pulmonary TB and provides implementation considerations for this treatment regimen. (cdc.gov)
  • We present findings from a follow up over 25 years of random samples from a population survey of 7 year old Tasmanian schoolchildren, designed to assess the natural course of asthma. (bmj.com)
  • Conclusion: Taken together, our findings suggest that some aspects of psychosocial function of older adults have improved across the two recent decades. (hu-berlin.de)
  • In a community sample aged 60-64 years, memory complaints were most closely related to psychiatric symptoms, personality characteristics and poor physical health. (nih.gov)
  • Consecutive adult patients aged 18 and above with chronic respiratory symptoms (lasting more than 8 weeks) and no evidence of active tuberculosis were recruited. (who.int)
  • Questionnaires were used to collect data on demographics, symptoms, diagnoses, and potential risk factors. (who.int)
  • Conclusion: This study demonstrated a high burden of abnormal lung function in patients attending clinics due to chronic respiratory symptoms. (who.int)
  • Group of symptoms affecting thinking & social abilities severe enough to interfere with daily functioning. (slideshare.net)
  • 2 3 Impaired lung function in childhood predicts asthmatic symptoms as a teenager, although this association might be confounded by undiagnosed asthma. (bmj.com)
  • These patients are usually younger than stroke patients in the general population and do not have the vascular risk factors. (medscape.com)
  • No study has established a relationship between factor V Leiden and arterial strokes, thus the incidence of this factor in patients with stroke is not known. (medscape.com)
  • Currently, one out of five patients diagnosed with most blood cancers is age 75 and above. (prnewswire.com)
  • Patients under 65 years of age were over-represented in trials for lymphomas, CLL, CML, and multiple myeloma compared with the incidence of those cancers in this age group. (prnewswire.com)
  • For example, researchers found that nearly 80 percent of patients enrolled in trials for CML were under 65, but only half of patients diagnosed with CML are in this age group. (prnewswire.com)
  • The good news, she adds, is that among patients aged 65 to 74, data show the proportion enrolled in lymphoma (excluding CLL) and CML trials essentially mirrored the reported incidence of blood cancers in this age group. (prnewswire.com)
  • This study aimed to explore if supplementary lycopene tablets may help heart failure (HF) patients improve their lipid profile, BP, and the flow-mediated dilation (FMD) index for endothelial function. (hindawi.com)
  • It can be concluded that supplementing with lycopene can enhance endothelial function and reduce the TG levels in ischemic HFrEF patients. (hindawi.com)
  • The 4-month RPT-MOX regimen is a treatment option for patients aged ≥12 years with drug-susceptible pulmonary tuberculosis. (cdc.gov)
  • This interim guidance updates 2016 guidelines by recommending and providing implementation considerations for a novel 4-month daily treatment regimen, based on high-dose daily RPT with MOX, INH, and PZA ( 1 ) as a treatment option for U.S. patients aged ≥12 years with drug-susceptible pulmonary TB. (cdc.gov)
  • CDC recommends the 4-month RPT-MOX regimen for treating patients aged ≥12 years with body weight ≥40 kg with pulmonary TB caused by organisms that are not known or suspected to be drug-resistant and who have no contraindications to this regimen. (cdc.gov)
  • The 5-year survival rate of EC patients is less than 20% ( 1 , 2 , 4 ). (frontiersin.org)
  • This study aimed to characterize the common chronic respiratory diseases, along with their lung function and possible determinants in symptomatic patients attending clinics at Bishoftu General Hospital, Ethiopia. (who.int)
  • Statistics show the cost of the care of patients with C1-4 tetraplegia at approximately $1,149,629 in the first year and approximately $199,637 for each subsequent year. (medscape.com)
  • Total direct costs for patients with SCI in the United States exceed $7 billion per year. (medscape.com)
  • Researchers also reported that hepatitis B patients who switched from the old tenofovir disoproxil fumarate (TDF) to TAF saw improvements in kidney function and bone density. (hivandhepatitis.com)
  • Among these 1298 patients, 239 had at least 1 risk factor that could make TDF inadvisable. (hivandhepatitis.com)
  • Efficacy results were similar in the subset of patients with kidney or bone risk factors. (hivandhepatitis.com)
  • This large-scale, multicenter, non-interventional, cross-sectional study examined the activity status of COPD patients in Japan and explored factors related to PA. (dovepress.com)
  • The age of patients ranged from 23 to 37 years with a mean age of 26.6±5.2 years. (spandidos-publications.com)
  • The chronification is reversible: about 26% of patients with chronic migraine go into remission within 2 years of chronification. (nature.com)
  • Due to the shortage of kidneys, patients on the waiting list for a deceased donor kidney may wait many years. (nih.gov)
  • Breast cancer patients who started taking one of two well-known heart medications at the same time they initiated trastuzumab-a targeted cancer therapy that has been linked to heart damage-received no benefit in terms of preventing declines in heart function, according to research presented at the American College of Cardiology's 67th Annual Scientific Session. (acc.org)
  • However, in patients who had received or were concurrently receiving anthracycline-based chemotherapy in addition to trastuzumab, the occurrence of heart damage was halved among those taking either the angiotensin converting enzyme inhibitor (ACE-inhibitor) lisinopril or beta blocker carvedilol, compared with placebo after two years of follow-up. (acc.org)
  • Patients were randomly assigned to receive once daily lisinopril (10 mg), carvedilol (10 mg Coreg CR) or placebo and were followed for two years (the year of active treatment with trastuzumab and the year that followed). (acc.org)
  • Patients are primarily older than age 60 years. (medscape.com)
  • 65 years), low thyroid hormone levels (hypothyroidism), and poor kidney function. (fda.gov)
  • Maria Buti of Vall d'Hebron University Hospital in Barcelona presented 96-week results from a pair of randomized Phase 3 studies comparing the safety and efficacy of TAF versus TDF, focusing on participants with risk factors for kidney problems or bone loss. (hivandhepatitis.com)
  • A transplant center can place you on the waiting list for a donor kidney if your kidney function is 20 or less -even if you aren't on dialysis. (nih.gov)
  • In 2018, 1.9% of the total disease burden in Australia was due to impaired kidney function (including chronic kidney disease). (aihw.gov.au)
  • These estimates reflect the amount of burden that could have been avoided if all people in Australia did not have impaired kidney function. (aihw.gov.au)
  • How much burden was attributable to impaired kidney function? (aihw.gov.au)
  • This interactive data visualisation shows the burden attributable to impaired kidney function by linked disease. (aihw.gov.au)
  • Each bar represents the attributable burden of the disease linked to impaired kidney function. (aihw.gov.au)
  • How did burden attributable to impaired kidney function vary by age and sex? (aihw.gov.au)
  • The majority of the total burden due to impaired kidney diseases occurred in older Australians- over the age of 65. (aihw.gov.au)
  • In ages 65 and under, the most burden due to impaired kidney function was from chronic kidney disease. (aihw.gov.au)
  • whereas females experience almost twice as much burden from impaired kidney function from age 85 onwards. (aihw.gov.au)
  • Each bar is also split into separate components with each colour representing a disease linked to impaired kidney function. (aihw.gov.au)
  • ABCD follows participants from the age of 9-10 into adulthood, collecting health and brain development information. (sciencedaily.com)
  • PARTICIPANTS: Participants were 6961 seventh-grade students (mean age 13 years). (bmj.com)
  • In both studies a majority of participants were men, most were Asian, and the average age was around 40 years. (hivandhepatitis.com)
  • All study participants had normal heart function measured by ejection fraction and were not already taking an ACE-inhibitor or beta blocker for other medical reasons. (acc.org)
  • In this cross-sectional study of BCSs on adjuvant treatment with endocrine therapy for at least three months, participants completed an online survey comprising standardized measures of sexual and psychosocial function. (aau.dk)
  • The mean age of included participants was 58.5 ± 7.2 years. (bvsalud.org)
  • The MMSE score of participants who had VI at baseline decreased by 1.7 ± 3.3 points on average during the six-year follow-up, and that of participants who had no VI at baseline decreased by 1.1 ± 3.3 points on average. (bvsalud.org)
  • Chronic respiratory diseases (CRDs) are diseases of such as age above 50years, being a smoker, being the respiratory airways and lung parenchyma. (who.int)
  • Moreover, age, female sex and low educational status increase the risk of chronic migraine. (nature.com)
  • This Review provides an up-to-date overview of the classification of chronic migraine, basic mechanisms and risk factors of migraine chronification, and the currently established treatment options. (nature.com)
  • Progressive deterioration in lung function results in increasing dyspnea, chronic cough, and frequent hospitalizations. (medscape.com)
  • There are a number reasons for the medical condition including genetic defects, reproductive system abnormalities, endocrine disorders, immune disorders, infection, thrombosis and environmental factors ( 2 ). (spandidos-publications.com)
  • In advanced stages, severe loss of brain function can cause dehydration, malnutrition or infection. (mayoclinic.org)
  • median age was 51 (Q1, Q3: 46, 55) years. (natap.org)
  • median age 51. (natap.org)
  • The median age of the five poor responders to Wyeth vaccine was 42 years, compared with 21 years for the responders. (cdc.gov)
  • The prognosis is poor and no cure has been found, with a reported median survival of 3-5 years from diagnosis . (medscape.com)
  • The nervous system is known to influence immune system function via neurotransmitters released by nerve terminals and indirectly via secretions from endocrine organs. (psychiatrictimes.com)
  • In turn, the immune system is known to influence nervous system function by cytokines and other peptides secreted by immune cells. (psychiatrictimes.com)
  • Working with a young adult choir (n = 71), we measured changes salivary concentrations of oxytocin, cortisol, and testosterone from before and after four experimental conditions crossing two factors: vocal production mode (singing vs. speaking) and social context (together vs. alone). (researchgate.net)
  • To determine which factors measured in childhood predict asthma in adult life. (bmj.com)
  • The subjects who had more severe asthma (especially if it developed after the age of 2 and was associated with reduced expiratory flow), were female, or had parents who had asthma were at an increased risk of having asthma as an adult. (bmj.com)
  • IPF is the most common interstitial lung disease among middle-aged and older adults . (medscape.com)
  • Relatively less is known about secular changes in other key components of psychosocial function among older adults. (hu-berlin.de)
  • Ganglioneuromas usually occur in people over 10 years of age. (medlineplus.gov)
  • Increases (especially after 65, not a normal part of aging), can occur in younger people. (slideshare.net)
  • 1 Asthma is episodic, and, although remission may occur during teenage years, it is uncommon after the age of 30. (bmj.com)
  • Due to biochemical reactions in your body that occur with every type of food you eat on a daily basis, some foods age you FASTER than your real age, while other foods help to FIGHT aging. (truthaboutabs.com)
  • CONCLUSIONS: The propensity to smoke for weight control reasons, previously described by other researchers among white females of college and high-school age, was also found among this sample of students of junior high school age. (bmj.com)
  • Researchers assessed heart function and any declines with echocardiograms every three months. (acc.org)
  • A recent study analyzed brain imaging data and chronological age (CA) information from twins and suggested that the brain aging process was heritable 14 . (nature.com)
  • Further studies are needed to determine the precise cause for these differences, such as whether lead exposure itself or other factors associated with living in a high lead-risk environment is contributing to this association, but the study unveils a clear correlation between family income and the effects of living in high lead-risk census tracts. (sciencedaily.com)
  • Some states were missing values because they did not meet the criteria for stable estimate analysis in all study years (6). (cdc.gov)
  • One 2013 study found that 1 in 4 men seeking their first treatment for ED was under 40 years old. (healthline.com)
  • In total, 333 BCSs with a mean age of 58.7 years were included in the study, of whom 227 were sexually active. (aau.dk)
  • Australian Institute of Health and Welfare (2021) Australian Burden of Disease Study 2018: Interactive data on risk factor burden , AIHW, Australian Government, accessed 29 September 2023. (aihw.gov.au)
  • The exposure factor of interest in this study was VI. (bvsalud.org)
  • Numerous risk factors have been identified that both predict the incidence of HF and its severity, including hypertension, obesity, smoking, dyslipidemia, and diabetes [ 3 - 5 ]. (hindawi.com)
  • Interpretation of individual testosterone measurements should account particularly for age older than 70 years, obesity, diabetes, and cancer. (lu.se)
  • EFFECTS OF HIV, AGE, AND SEX ON SKELETAL MUSCLE MASS AND DENSITY (04/01/20) "Older age and being a woman was associated with smaller and fattier muscle, while obesity was associated with larger and fattier muscle. (natap.org)
  • Gender and age were factors that modified outcomes. (uwo.ca)
  • Better health for people with disabilities, through improved access to health services, is a crucial enabling factor to participation and positive outcomes in areas such as education, employment, and family, community and public life. (who.int)
  • Pulmonary function tests fulfil a pivotal role in respiratory medicine. (ersjournals.com)
  • Unlike the majority of biological indices in medicine, such as plasma concentrations of chemical analytes or hormones, pulmonary function varies with age, standing height, sex and ethnicity. (ersjournals.com)
  • Also many prediction equations are based on small numbers of subjects, using data collected decades ago so that changes in spirometric methodology and secular trends ( i.e . a trend in pulmonary function in successive birth cohorts) may affect the applicability to present day measurements. (ersjournals.com)
  • Outpatients aged ≥ 40 years with confirmed COPD diagnosis and pulmonary function test data were enrolled. (dovepress.com)
  • The magnitude of the disparity is particularly concerning given that the number of adults aged 75 and older who are diagnosed with blood cancers is only expected to rise as the population ages. (prnewswire.com)
  • 15 studies involving adults (aged 20-80 years) were included. (researchgate.net)
  • While associations between individual human brain regions and environmental or genetic factors have been investigated, how brain age is associated with those factors remains unclear. (nature.com)
  • Our results suggest that both environmental and genetic factors are associated with structural brain aging. (nature.com)
  • Besides lifestyle habits, genetic factors are also thought to be involved in brain aging. (nature.com)
  • Therefore, we also investigated if genetic factors are associated with brain aging in addition to smoking and alcohol consumption. (nature.com)
  • Therefore, it is important to explore if there is genetic and environmental factor interaction in association with brain aging. (nature.com)
  • Scientists believe that MS is triggered by a combination of environmental and genetic factors. (medicinenet.com)
  • Although the cause of IPF is unknown, risk factors include a history of smoking, family history, and genetic predispositions. (medscape.com)
  • ABSTRACT Old-age disability has become a public health concern. (who.int)
  • Dyslipidemia, identified as increased low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), triglyceride (TG) levels, and/or decreased high-density lipoprotein cholesterol (HDL-C), is found to be associated with decreased systolic and diastolic left ventricular function and increased risk of cardiovascular disease (CVD) [ 6 - 9 ]. (hindawi.com)
  • The groups were comparable in terms of age (average of 51 years) and cardiovascular risk factors. (acc.org)
  • [ 2 ] and antithrombin III, sickle cell anemia, hyperhomocystinemia, antiphospholipid syndrome (APS), hereditary disorders of fibrinolysis, and certain acquired conditions leading to abnormal platelet function and hypercoagulable state. (medscape.com)
  • 2004). In addition, age at menarche (first menstrual period), premenopausal ammenorrhea (absence or discontinuation or abnormal stoppage of the menstrual periods), and postmenopausal status may negatively impact OP risk in women. (unm.edu)
  • After discarding 23,572 records, mostly because they could not be combined with other ethnic or geographic groups, reference equations were derived for healthy individuals aged 3-95 yrs for Caucasians (n=57,395), African-Americans (n=3,545), and North (n=4,992) and South East Asians (n=8,255). (ersjournals.com)
  • OP-related fractures added 17 billion dollars to health care costs in the US in 2001 (Notelovitz, 2003) and it is responsible for more than 1.5 million fractures per year (Brynin, 2002). (unm.edu)
  • BMD may be lost at a rate of 5% for every 5 years after the age of 65 (Pachucki-Hyde, 2001). (unm.edu)
  • The EAC met twice during the course of the project, once on a telephone conference in mid-2000 prior to the start of data collection and again in Rochester on June 20, 2001, after about one year of data collection. (cdc.gov)
  • In conclusion, bronchial hyperresponsiveness and a low level of lung function in childhood are independent risk factors for a low level of FEV 1 in early adulthood. (atsjournals.org)
  • This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked. (drugs.com)
  • Although the risk of ED increases with age, ED isn't inevitable. (healthline.com)
  • Eliminating data that could not be used (mostly missing ethnic group, some outliers) left 97,759 records of healthy nonsmokers (55.3% females) aged 2.5-95 yrs. (ersjournals.com)
  • Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were performed to explore the function of splicing factors (SFs) that were associated with AS events. (frontiersin.org)
  • Multiple regression analyses were performed to identify factors significantly associated with SD. (aau.dk)
  • About 6.5 million people in the United States age 65 and older live with Alzheimer's disease. (mayoclinic.org)
  • Between 1966 and 1969, 119 allergic asthmatic subjects aged 5 to 14 yr were studied (Visit 1). (atsjournals.org)
  • Risk factors included older age and non-Hispanic black ethnicity. (natap.org)
  • Our data stress the importance of studying intervention strategies for asthma in young childhood and early adulthood in order to prevent or postpone further lung function deficits. (atsjournals.org)
  • The wealth of data collected through ABCD allows investigators like Dr. Sowell to ask questions about factors that affect adolescent brains. (sciencedaily.com)
  • Over 160,000 data points from 72 centres in 33 countries were shared with the European Respiratory Society Global Lung Function Initiative. (ersjournals.com)
  • Lung function data were collated and prediction equations derived using the LMS method, which allows simultaneous modelling of the mean (mu), the coefficient of variation (sigma) and skewness (lambda) of a distribution family. (ersjournals.com)
  • provides functions which are suitable for different data transformation and modeling tasks such as: imputations, monotonic binning of numeric risk factors, binning of categorical risk factors, weights of evidence (WoE) and information value (IV) calculations, WoE coding (replacement of risk factors' modalities with WoE values), risk factor clustering, area under curve (AUC) calculation and others. (r-project.org)
  • The main section shows a horizontal bar graph which can be customised to report data according to year, sex and measure of attributable burden. (aihw.gov.au)
  • CONCLUSIONS: These data provide benchmarks for evaluating impairments in adolescents with CP and support the role of function in contracture development and possibly prevention. (uwo.ca)
  • The heterozygous state, unlike the homozygous state, has not been shown to be a risk factor for recurrent venous thromboembolism. (medscape.com)
  • Reports indicate that a G-to-A transition at nucleotide position 20210 (G20210A) in the prothrombin gene is considered a risk factor for cerebral venous thrombosis. (medscape.com)
  • Finally, the risk score of prognostic signatures was indicated as an independent risk factor of survival. (frontiersin.org)
  • Most had 1 risk factor, but some had 2 or more. (hivandhepatitis.com)
  • Results of the multivariable Logistic regression model showed that VI was a risk factor for CFI, with an OR of 1.052 (95%CI 1.014 to 1.092, p = 0.017). (bvsalud.org)
  • VI is an independent risk factor for CFI. (bvsalud.org)
  • Ninety-nine cognitively normal men and women (aged 60-80 years) were enrolled from October 2016 to November 2017. (springer.com)
  • Gestational age ranged from 4.5 to 12 weeks, and an average age of 8.3±3.9 weeks. (spandidos-publications.com)
  • 32 weeks gestation (Gestational age as determined by the neonatologist by Ballard exam). (cdc.gov)
  • This suggests that lifestyle choices are an important factor for ED in younger men. (healthline.com)
  • Avoid or minimize these and look 5-10 years YOUNGER than your real age. (truthaboutabs.com)
  • but eat the right foods, and over time, you can start to look 5-10 years YOUNGER than your real age. (truthaboutabs.com)
  • Your body will thank you by aging slower and looking YOUNGER! (truthaboutabs.com)
  • They were also significantly underrepresented in trials of new treatments for lymphoma, CLL, and multiple myeloma compared with the incidence of each of these cancers in that age group. (prnewswire.com)
  • In multiple myeloma and CLL trials, the proportion enrolled in the 65-74-year-old age group was higher than the reported incidence in this group. (prnewswire.com)
  • Traumatic SCI accounts for an estimated annual incidence of approximately 54 cases per million population, or approximately 17,810 new cases each year, in the United States. (medscape.com)
  • Incidence rates increased during the surveillance period by 60.7% and were more common with increasing age. (health.mil)
  • More than 4,400 individuals received incident diagnoses of CSCR during the 18-year surveillance period. (health.mil)
  • OBJECTIVE: To describe distributions of contracture and spinal malalignment in adolescents with cerebral palsy (CP) and determine associations with age, gender and function. (uwo.ca)