• clinical
  • AD patients (n = 421) were recruited from a clinical multi-centre study program in Sweden. (springer.com)
  • Methods Clinical and radiographic 5-year outcome was compared between initial strategies. (bmj.com)
  • At 5 years there was no longer any significant difference for clinical and radiographic outcomes between treatment strategies applied during the first 2 years. (bmj.com)
  • Good-response to treatment independently predicts significantly better 5-year clinical and radiographic outcome. (bmj.com)
  • Objective: The objective of this 6 year prospective randomized equivalence trial was to evaluate the long-term clinical performance of a new nano-hybrid resin composite (RC) in Class II restorations in an intraindividual comparison with its well-established conventional hybrid RC predecessor. (diva-portal.org)
  • No statistical significant difference was found in the overall survival rate between the two investigated RC.Significance: The nano-hybrid RC showed good clinical performance during the 6 year evaluation, comparable to the well-established conventional hybrid RC. (diva-portal.org)
  • Two years after Zyprexa was approved, a series titled "Doing Harm: Research on the mentally ill," by Bob Whitaker, was published on the front page of the Boston Globe, on Nov 15-18, 1998, and reported that in pre-marketing clinical trials, Zyprexa was linked to life-threatening adverse effects in 22% of the adult patients tested. (blogspot.com)
  • Patients were interviewed one week before, six months after, and two years after surgery using a standardized questionnaire including the SF-36, the Oxford Knee Score (OKS), and the Knee Society Clinical Rating Scale (KSS). (biomedsearch.com)
  • Clinical trials are also underway to reduce treatment duration of drug resistant TB from two years to six months," Swaminathan said. (indianexpress.com)
  • In accordance, all other clinical parameters showed sustained improvement during year 2. (wiley.com)
  • The clinical efficacy and safety of etanercept in patients with active AS without simultaneous administration of DMARDs or steroids over 2 years of continuous treatment is confirmed. (wiley.com)
  • At the same time patients had a full clinical examination and blood was sampled for glucose, HbA1c, IGF-1, creatinine, full blood count, thyroid hormones and liver function tests. (ac.be)
  • Agencies of drugs, committee of ethics and organizations of patients' safety should consider: Requiring that clinical trials run long enough to pick up evidence of side effects and record all adverse reactions, including in subjects who drop out. (wikipedia.org)
  • In most countries, psychotherapy trainings are all at a post-graduate level, often at Master's degree (or doctoral) level, over a 4-year period, with significant supervised practice and clinical placements. (wikipedia.org)
  • Outcome Measures
  • Main outcome measures The primary outcome measure was the score on the Oswestry disability index after two years. (bmj.com)
  • Secondary outcome measures were low back pain, satisfaction with life (SF-36 and EuroQol EQ-5D), Hopkins symptom check list (HSCL-25), fear avoidance beliefs (FABQ), self efficacy beliefs for pain, work status, and patients' satisfaction and drug use. (bmj.com)
  • initially
  • As an aid we constructed three algorithms corresponding to the cognitive domains, which can be used to characterize patients initially, identify rapid decliners and follow the course of the disease. (springer.com)
  • Patients receiving low-intensity ICBT showed a significant reduction in distress, even when they had low levels of distress initially. (diva-portal.org)
  • baseline
  • The restorations were evaluated with slightly modified USPHS criteria at baseline and then annually during 6 years. (diva-portal.org)
  • The primary outcome was a Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) improvement ≥50% after 2 years of etanercept therapy compared with the baseline value of the study. (wiley.com)
  • Mean ± SD BASDAI scores, which were elevated at baseline (6.3 ± 1.6), remained low: 2.7 ± 2.4 after 2 years compared with 2.6 ± 2.2 at week 54. (wiley.com)
  • asymptomatic
  • not in citation given] perhaps because people do not feel immediately threatened or, in the case of symptomless conditions such as raised cholesterol levels (hypercholesterolaemia) and raised blood pressure (systemic hypertension), feel no obvious benefits at the time of taking the medicines As patients are asymptomatic, they may not see a need to take medication. (wikipedia.org)
  • high
  • A prediction of the caries risk showed that 16 of the evaluated 52 patients were considered as high risk patients. (diva-portal.org)
  • The finding of suboptimal high or low IGF-1 levels in many patients reinforces guidelines not to give rhGH in a weight-dependent dose but to titrate it individually for each patient. (ac.be)
  • Madison High School is a four-year public high school serving students in ninth to twelfth grades in Morris County, New Jersey, United States, operating as part of the Madison Public Schools. (wikipedia.org)
  • Madison High School offers four world languages (Spanish, French, and Italian, and new in the 2009-10 school year, Mandarin), in addition to a full array of academic majors in English, History, Mathematics and Science. (wikipedia.org)
  • Due to their high reactivity to environmental stimuli, patients with BPD often experience dramatic and short-lived shifts in their mood, alternating between experiences of euphoria, depression, anxiety, and nervousness. (wikipedia.org)
  • This procedure is mostly carried out on patients with so-called drop attacks that come with a very high risk of injury and in which the epileptic focus is not clearly delimitable. (wikipedia.org)
  • A comparison between the sales of modafinil to the number of patients revealed a disproportionate ratio, indicating high abuse. (wikipedia.org)
  • Modafinil has a market share of more than $700 million a year, indicating a high degree of off-label use. (wikipedia.org)
  • chronic
  • 2003 estimates from the World Health Organization indicated that only about 50% of patients with chronic diseases living in developed countries follow treatment recommendations with particularly low rates of adherence to therapies for asthma, diabetes, and hypertension. (wikipedia.org)
  • A WHO study estimates that only 50% of patients suffering from chronic diseases in developed countries follow treatment recommendations. (wikipedia.org)
  • citation needed] This may affect patient health, and affect the wider society when it causes complications from chronic diseases, formation of resistant infections, or untreated psychiatric illness. (wikipedia.org)
  • Objective To compare the efficacy of surgery with disc prosthesis versus non-surgical treatment for patients with chronic low back pain. (bmj.com)
  • Schema therapy was developed by Jeffrey E. Young for use in treatment of personality disorders and chronic DSM Axis I disorders, such as when patients fail to respond or relapse after having been through other therapies (for example, traditional cognitive behavioral therapy). (wikipedia.org)
  • MHNs act to bridge the gap between mental health services and general practice for patients suffering from acute to chronic mental illnesses. (wikipedia.org)
  • rates
  • Cumulative dropout rates were 29% after 1 year and 38% after two years. (ac.be)
  • Advances in the treatment of pediatric cancers has resulted in significant gains in 5 year survival rates, increasing from 58.6% (1974-1976) to 78.9% (1995-2001) However, even after successfully completing treatment, concerns remain about the quality of life of youth diagnosed with cancer. (wikipedia.org)
  • Phase IIb data presented at the 20th Conference on Retroviruses and Opportunistic Infections (CROI) in March 2013 showed similar viral suppression rates of 76% for patients taking 100 mg cenicriviroc, 73% with 200 mg cenicriviroc, and 71% with efavirenz. (wikipedia.org)
  • Non-response rates were higher with cenicriviroc, however, largely due to greater drop-out of patients. (wikipedia.org)
  • duration
  • Short term dropouts tended to be less likely than long term terminators to report a disturbance with their child, more likely to report a sleep disturbance or sexual dysfunction and more likely to have a complaint longer in duration. (ed.gov)
  • therapist
  • Moreover, it has not been evaluated if a low-intensity version of ICBT without therapist contact could be an alternative for patients who do not need or are able to manage the full ICBT-program. (diva-portal.org)
  • Adult
  • OBJECTIVES: Although several studies have shown beneficial short-term effects of recombinant human growth hormone (rhGH) therapy in adult GH deficient (GHD) patients, few data are available on large groups of patients treated for more than one year. (ac.be)
  • often
  • Approximately half of all patients develop metastases, often to the liver or lung. (clinicaltrials.gov)
  • About one third of patients on rhGH experienced fluid-related adverse events, most often within the first 3 months. (ac.be)
  • Patients with BPD are often characterized by intense affects, stormy relationships, and impulsive behaviors. (wikipedia.org)
  • Patients with BPD often experience intolerable feelings of emptiness that they attempt to fill with impulsive and self-damaging behaviors, such as substance abuse, risky sexual behavior, uncontrolled spending, or binge eating. (wikipedia.org)
  • The Patient Protection and Affordable Care Act, often shortened to the Affordable Care Act (ACA) or nicknamed Obamacare, is a United States federal statute enacted by the 111th United States Congress and signed into law by President Barack Obama on March 23, 2010. (wikipedia.org)
  • The functional hemispherectomy can achieve long-term seizure freedom in over 80% of patients however often at the price of hemiplegia and hemianopsy. (wikipedia.org)
  • study
  • All patients received donepezil starting directly after study entry. (springer.com)
  • Data for the other patients were analysed until they dropped out (4 groups based on length in study). (springer.com)
  • What distinguishes patients that actually complete a three-year study from those who drop out, for example in pattern of cognitive reduction, needs to be further investigated. (springer.com)
  • Study end-points: The major end-point: hepatitis B reactivation in NHL patients---defined by higher than 10-fold increase of serum HBV DNA level and/or reappearance of HBeAg in the serum during and within 6 months after chemotherapy. (clinicaltrials.gov)
  • While the FDA allowed Lilly to subject patients to the risks associated with the drug, a recent study published in the September 2005 New England Journal of Medicine, found that although Zyprexa was the most expensive and most prescribed antipsychotic, it was only slightly more effective than the cheaper 40-year-old generic drug, Perphenazine. (blogspot.com)
  • Results The study was powered to detect a difference of 10 points on the Oswestry disability index between the groups at two years. (bmj.com)
  • This study will offer live donor liver transplantation (LDLT) to select patients with unresectable metastases that are 1) limited to the liver and 2) stable (non-progressing) on standard chemotherapy. (clinicaltrials.gov)
  • Registration must be renewed every three years, for which 450 hours of registered practice and 35 hours of study must have been completed in the past three years. (wikipedia.org)
  • Enrollment
  • As of the 2014-15 school year, the school had an enrollment of 837 students and 65.8 classroom teachers (on an full-time equivalent [FTE] basis), for a student-teacher ratio of 12.7:1. (wikipedia.org)
  • With 634 students in grades 10-12, the school was classified by the NJSIAA for the 2015-16 school year as North II, Group II for most athletic competition purposes, which included schools with an enrollment of 508 to 770 students in that grade range. (wikipedia.org)
  • versus
  • Surgery offers a distinct survival advantage: the 5-year survival after liver resection for LM is around 40-50% in most studies versus 10-20% 5-year survival for chemotherapy alone. (clinicaltrials.gov)
  • Criteria
  • Patients were classified according to the EULAR response criteria. (bmj.com)
  • In the intent-to-treat analysis, 54% of the patients showed a 50% improvement according to the BASDAI and a 40% improvement according to the Assessment in Ankylosing Spondylitis (ASAS) criteria. (wiley.com)
  • In the completer analysis, 9 (43%) of 21 patients were in partial remission according to ASAS criteria. (wiley.com)
  • significantly
  • Spinal inflammation as depicted by MRI decreased significantly, but a few patients still had some spinal inflammation even after long-term anti-TNF therapy. (wiley.com)
  • adverse events
  • In July 2002 issue of Pharmacotherapy, P Murali Doraiswamy, the chief of biological psychiatry at Duke University, published a review of adverse events reported to the FDA by Zyprexa patients that found 289 cases of diabetes, 100 patients with ketosis (a serious complication of diabetes), and 22 cases of pancreatitis, a life-threatening condition. (blogspot.com)
  • group
  • Of the 1405 consecutive TMD patients examined in a recent 10-year period, 367 (26.1%) drop-out pati ents or patients identified with a control group were sampled. (quintpub.com)
  • A group of patients who were judged by the examiner not to need treatment were included as a control group. (quintpub.com)
  • The change in weight over 3 years was -1.1 in the NP group and -0.5 in the GP group (p = 0.34). (acc.org)
  • 50 patients), according to a parallel group design in one centre. (quintessenz.de)
  • This procedure is only performed on a small group of patients under the age of 13 that have severe damage or malformation of one hemisphere, patients with Sturge Weber syndrome or patients with Rasmussen's encephalitis. (wikipedia.org)
  • severe
  • Around 30 to 40 per cent of patients who begin TB medication experience severe side effects, including hyperacidity, jaundice, loss of vision, vertigo and numbness in the limbs. (hindustantimes.com)
  • It is very rare that a corpus callosotomy causes seizure freedom however in half of the patients the dangerous drop attacks are less severe. (wikipedia.org)
  • Objective
  • The objective was to identify separate cognitive domains in the standard assessment tools (MMSE, ADAS-Cog) and analyze the process of decline within domains during three years in Alzheimer's disease (AD) patients with donepezil treatment. (springer.com)
  • prosthesis
  • Purpose: To compare prosthesis and implant failure, patient satisfaction, prosthetic complications and peri-implant marginal bone loss of mandibular overdentures (IOD) supported by a single or two implants. (quintessenz.de)
  • disorders
  • Although patient attrition might be a serious threat to the validity of treatment-outcome studies on temporomandibular disorders (TMD), studies on TMD patient attrition are scarce. (quintpub.com)
  • There has traditionally been skepticism about the psychological treatment of personality disorders, but several specific types of psychotherapy for BPD have developed in recent years. (wikipedia.org)
  • Specific psychotherapies may involve sessions over several months or, as is particularly common for personality disorders, several years. (wikipedia.org)
  • Pharmalogical neuroenhancement agents include the well-validated nootropics, such as racetam, vinpocetine, and phosphatidylserine, as well as other drugs used for treating patients suffering from neurological disorders. (wikipedia.org)
  • Modafinil is currently licensed for treating patients with disorders such as narcolepsy, sleep apnea, and shift work sleep disorder. (wikipedia.org)
  • needs
  • The findings suggest that the dropouts meet their treatment needs in a short term manner. (ed.gov)
  • Psychosocial interventions: A holistic approach to patient care is required, by which the MHN should build rapport with patients to encourage trust, while listening to and interpreting their needs and concerns. (wikipedia.org)
  • outcomes
  • In the analysis of prespecified secondary outcomes, there were significant differences in favour of surgery for low back pain (mean difference −12.2, −21.3 to −3.1), patients' satisfaction (63% (n=46) v 39% (n=26)), SF-36 physical component score (mean difference 5.8, 2.5 to 9.1), self efficacy for pain (mean difference 1.0, 0.2 to 1.9), and the Prolo scale (mean difference 0.9, 0.1 to 1.6). (bmj.com)
  • Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up. (biomedsearch.com)
  • OBJECTIVES: To quantify the improvement in health outcomes in patients after total knee replacement (TKR). (biomedsearch.com)
  • interventions
  • Such data may provide hints as to the causal mechanisms and will have consequences for planning interventions for the individual patient, and for developing support systems for AD patients on the societal level. (springer.com)
  • If a patient is having social/financial problems, the MHN may offer advice and interventions e.g. by arranging social events in the community, in order to develop patients' socials skills and combat feelings of isolation. (wikipedia.org)
  • groups
  • 4 ] described six groups of attributes of QoL of dementia patients: global impression of QoL, physical well-being, social/family well-being, emotional well-being, functional well-being, and cognition, whereas Rabins et al. (hindawi.com)
  • counsel
  • Doctors should counsel the patients properly about side effects before starting treatment so that the patients do not press the panic button," said Dr Jaising Phadtare, honorary professor, GT Hospital. (hindustantimes.com)
  • However, the majority of physicians do not routinely counsel patients regarding lifestyle modification. (acc.org)
  • emotional
  • The patient and family are the unit to be treated: emotional support and communication with the patient, family and treatment team must be through a frank and honest. (wikipedia.org)
  • Promoting autonomy and dignity of the patient with the sense of preserving and restoring all abilities, both practical and emotional and relational patients. (wikipedia.org)
  • DBT can be based on a biosocial theory of personality functioning in which BPD is seen as a biological disorder of emotional regulation in a social environment experienced as invalidating by the borderline patient. (wikipedia.org)
  • Pharmaceutical
  • Disease mongering Health policy Inverse care law Medicalization Patient safety Pharmaceutical company Pharmaceutical marketing Public health Quaternary prevention Medical science liaison Brody H, Light DW. (wikipedia.org)
  • Patrick Girondi is an Italian/American singer, composer and pharmaceutical executive/patient advocate. (wikipedia.org)
  • disease
  • Overall, 26 patients with active AS were treated with etanercept 25 mg twice daily subcutaneously, twice weekly with no concomitant disease-modifying antirheumatic drugs (DMARDs) or steroids. (wiley.com)
  • The majority of patients had no disease activity flares. (wiley.com)
  • House concludes Ian has ataxia and begins to assume Ian has the same disease as a former patient from 12 years ago, 73-year old Esther Doyle, who died under House's care and was never correctly diagnosed. (wikipedia.org)
  • dissociative
  • Under intense stress patients with BPD may exhibit transient dissociative or paranoid symptoms. (wikipedia.org)
  • As work begins inside the asylum, Mike finds a box containing nine taped sessions with a patient named Mary Hobbes, who suffered from dissociative identity disorder. (wikipedia.org)
  • Mumbai
  • In Mumbai, Hinduja Hospital has already procured Delamanid on a case-by-case basis to treat patients that have stopped responding to most of first and second line drugs. (indianexpress.com)
  • care
  • Both patient and health-care provider affect compliance, and a positive physician-patient relationship is the most important factor in improving compliance, The cost of prescription medication also plays a major role. (wikipedia.org)
  • Major barriers to compliance are thought to include the complexity of modern medication regimens, poor "health literacy" and not understanding treatment benefits, occurrence of undiscussed side effects, poor treatment satisfaction, cost of prescription medicine, and poor communication or lack of trust between a patient and his or her health-care provider. (wikipedia.org)
  • A Mental Health Nurse (MHN) refers to a psychiatric nurse in the UK, who specialises in the care of patients with mental health issues. (wikipedia.org)
  • The role of an MHN has gradually transitioned over the years, to encompass a greater level of involvement in patient care e.g. nurses now have authority to prescribe medication. (wikipedia.org)
  • The MHN will prepare and maintain comprehensive patient records, whilst also producing care plans and risk assessments. (wikipedia.org)
  • Working with dual diagnosis patients, and promoting a 'recovery' based approach to care. (wikipedia.org)
  • candidates
  • For those patients who are not surgical candidates, those who decline brain surgery or those in which brain surgery fails to produce long term seizure freedom, vagus nerve stimulation and/or a diet can be recommended. (wikipedia.org)
  • medication
  • Efforts to improve compliance have been aimed at simplifying medication packaging, providing effective medication reminders, improving patient education, and limiting the number of medications prescribed simultaneously. (wikipedia.org)
  • Patients, especially those from economically disadvantaged families, do not eat a balanced diet while on medication. (hindustantimes.com)
  • personality
  • Extrovert personality measured by Eysenck's Personality Inventory and active coping strategy predicted improved ADL functions among former stroke patients at the three years follow-up stage [ 10 ]. (hindawi.com)