AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth CareGeographicals
MacrolidesPrevalenceSteroidsErythromycinAnti-Bacterial AgentsAzithromycinKetolidesRoxithromycinJosamycinLeucomycinsTylosinMicrobial Sensitivity TestsChild WelfareClarithromycinDisabled ChildrenChild BehaviorSpiramycinLincosamidesDrug Resistance, BacterialCross-Sectional StudiesVirginiamycinRisk FactorsGonadal Steroid HormonesStreptococcus pneumoniaeReceptors, SteroidMiocamycinRNA, Ribosomal, 23SClindamycinDrug Resistance, MicrobialAge FactorsChild Health ServicesStreptograminsChild RearingLincomycinQuestionnairesChild, InstitutionalizedPolyenesUnited StatesChild Behavior DisordersRetrospective StudiesFluoroquinolonesMycoplasma pneumoniaeStreptococcus pyogenesChild PsychologyInfant, NewbornAge DistributionAnti-Infective AgentsSex FactorsProspective StudiesChild of Impaired ParentsTime FactorsStreptogramin BDrug Resistance, Multiple, BacterialChild, OrphanedPneumococcal InfectionsDental Care for ChildrenParentsBrazilPregnancySex DistributionSocioeconomic FactorsChild Nutrition DisordersSteroid 21-HydroxylaseRespiratory Tract InfectionsTreatment OutcomeIncidenceStreptomycesRural PopulationBronchiolitisHealth SurveysMoraxella (Branhamella) catarrhalisCommunity-Acquired InfectionsChild Nutritional Physiological PhenomenaAsthmaUrban PopulationOleandomycinLactamsIndiaHaemophilus influenzaeTetracyclinesStreptococcal InfectionsLogistic ModelsFollow-Up Studies4-QuinolonesPneumonia, MycoplasmaChild LanguageSpainMycoplasma hominisProgesteroneDrug UtilizationAnabolic AgentsPolymerase Chain ReactionChild MortalityGlucocorticoidsEstradiolAnti-Inflammatory AgentsObesityCase-Control StudiesMothersSeverity of Illness Index
European Respiratory SocietyAntibioticsInfections such as pneumoniaAcutePneumoniaeClinicalPathogensAnti-inflammatory propertiesPneumoniaPenicillinAirwayAntibioticTract infectionsResistanceClinicallyInfantsChronic2019PrevalentRhinosinusitisDiseaseSevereAlleviateSignificantly2018PediatricOutcomesVariesNasalWidelyDiffuseChildren'sEstimatesImmuneClinicSymptomsHighEpisodesMETHODSCommonlyInfluenzaPreventionAdults and childrenLowerPatientsTherapyRatePatientOnsetResearchProperties
European Respiratory Society1
  • Comprehensive evidence syntheses, including meta-analyses, were performed to summarise all available evidence relevant to the European Respiratory Society/American Thoracic Society Task Force's questions. (ersjournals.com)
Antibiotics3
  • Of note, some experts question the use of antibiotics for the treatment of GAS infection in the Western world because of the low prevalence of rheumatic fever. (medscape.com)
  • Macrolide antibiotics are used as first-line agents in the treatment of acute bacterial infections, such as community-acquired pneumonia 1 . (ersjournals.com)
  • Azithromycin is one of the commonly used antibiotics from the macrolide group. (ijtpr.com)
Infections such as pneumonia2
  • The best way to prevent serious respiratory infections such as pneumonia is to avoid sick people (if possible) and to practice good hygiene. (adam.com)
  • All of the serotypes, particularly type b, are common etiological agents in lower respiratory tract infections such as pneumonia. (statpearls.com)
Acute10
  • However, life-threatening pneumonia or even acute respiratory distress syndrome requiring extracorporeal membrane oxygen has been reported ( 3 ). (cdc.gov)
  • Recurrent acute sinusitis[2] is diagnosed when 2-4 episodes of infection occur per year with at least 8 weeks between episodes, and, as in acute sinusitis, the sinus mucosa completely normalizes between attacks. (medscape.com)
  • Computed tomography (CT) scanning has poor specificity for the diagnosis of acute sinusitis, demonstrating sinus air-fluid levels in 87% of individuals with simple upper respiratory tract infections (URTIs) and 40% of asymptomatic individuals. (medscape.com)
  • If a macrolide is used to treat GAS, patients should be followed closely for treatment failure, as very rare case reports describe acute rheumatic fever after GAS treatment with macrolides. (medscape.com)
  • Dermatosis is defined as a disorder involving lesions or eruptions of the skin that are acute (lasting days to weeks) or chronic (lasting months to years). (uspharmacist.com)
  • Children infected with respiratory syncytial virus (RSV) had a low serum concentration of vitamin A during acute illness, and these low values were associated with more severe illness. (indexarticles.com)
  • 2021) Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Infection on Pregnancy Outcomes: A Population-based Study. (vircell.com)
  • COVID-19 (coronavirus disease 2019) is the disease resulting from infection by the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus. (bvsalud.org)
  • The case fatality rate of COVID-19 is debated but appears to be lower than Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS), with an estimated 5% of those experiencing symptoms requiring hospitalisation. (bvsalud.org)
  • A primary form is an acute, benign, self-limited respiratory infection. (lookformedical.com)
Pneumoniae11
  • A high prevalence rate of macrolide-resistant Mycoplasma pneumoniae (MRMP) has been reported in Asia. (cdc.gov)
  • We performed a systematic review and meta-analysis to investigate the effect of macrolide resistance on the manifestations and clinical judgment during M. pneumoniae infections. (cdc.gov)
  • We found no difference in clinical severity between MRMP and macrolide-sensitive Mycoplasma pneumoniae (MSMP) infections. (cdc.gov)
  • Macrolides are the first-line therapy for M. pneumoniae . (cdc.gov)
  • During the past 10 years, however, macrolide-resistant Mycoplasma pneumoniae (MRMP) has emerged worldwide. (cdc.gov)
  • We conducted a systematic literature search in PubMed, Embase, and the Cochrane Library database using the keywords Mycoplasma pneumoniae , macrolide, antibiotic resistance, and drug resistance. (cdc.gov)
  • and a direct comparator was used in the same cohorts (macrolide-sensitive M. pneumoniae [MSMP] group). (cdc.gov)
  • For instance, if the patient has been diagnosed with M pneumoniae -associated EM, a macrolide or tetracycline should be administered. (uspharmacist.com)
  • We developed and assessed the performance of a new multiplex real-time PCR assay for the detection of all Chlamydia species and simultaneous differentiation of Chlamydia psittaci and Chlamydia pneumoniae-two important human respiratory pathogens-in human clinical specimens. (cdc.gov)
  • Therefore, we evaluated whether sufficient metabolic differences are present, which distinguish the volatile metabolome of Group A streptococci from other streptococcal species that also colonize the respiratory mucosa, such as Streptococcus pneumoniae and Streptococcus intermedius. (bvsalud.org)
  • Tetracyclines are highly effective in the treatment of most chlamydial infections, including urogenital infections caused by Chlamydia trachomatis, respiratory tract infections caused by C. pneumoniae, respiratory tract infections caused by C. psittaci (psittacosis), and lymphogranuloma venereum caused by invasive serovars of C. trachomatis. (antiinfectivemeds.com)
Clinical9
  • Although the dominant clinical features of CF are lower respiratory tract infections and pancreatic insufficiency, the vast majority of CF patients will also develop chronic rhinosinusitis due to sinonasal mucus accumulation [ 2 - 5 ]. (hindawi.com)
  • In addition to direct antibacterial actions, 14- and 15-member-ring macrolides have immune modulating effects that appear to be the reason for clinical benefit in diffuse panbronchiolitis. (ersjournals.com)
  • A literature search was conducted for studies of the clinical effectiveness of macrolides in other chronic lung conditions. (ersjournals.com)
  • The potential clinical benefit of these properties was first investigated in steroid-dependent asthma 4 . (ersjournals.com)
  • 7 , in a 2-yr double-blind placebo-controlled study, showed that the combination of macrolide and methylprednisolone produced no significant clinical benefit in steroid-dependent asthma but, instead, resulted in an increase in steroid-induced side-effects, e.g. accelerated loss of bone density and increased sugar levels. (ersjournals.com)
  • The chance finding that erythromycin treatment radically improved the clinical outcome of a patient with diffuse panbronchiolitis rekindled interest in the use of macrolides as a potential treatment in other inflammatory airway disorders, e.g. cystic fibrosis 8 . (ersjournals.com)
  • The American Journal of Respiratory and Critical Care Medicine started the new year with a review article [ 2 ] summarizing what we know about the different clinical, cellular, and molecular types of asthma. (medscape.com)
  • While the clinical translation and implementation of in vitro results to the bedside remains challenging, advances in comprehending the mechanisms of respiratory medication are expected to assist clinicians and scientists in identifying meaningful read-outs and designing clinical studies. (ersjournals.com)
  • Der Datenschutzbeauftragte des Landes Bremen forderte die Effective in controlling the clinical and growth-limiting effects of respiratory disease as continuous http://abadiepaper.com/__media__/js...r/g5/bbs/board.php?bo_table=free&wr_id=606093 Franklin won by Wiradjuri author Tara June Winch for novel of family, history and language. (noichuyenhay.com)
Pathogens3
  • Obstruction of the ostia leads to ciliary injury, mucosal edema, and general inflammation, which is further exacerbated by chronic colonization, in most cases with pathogens of the upper and lower respiratory tract such as Pseudomonas species, Staphylococcus aureus , and nontypable Haemophilus influenzae [ 7 ]. (hindawi.com)
  • However, with the advent of novel diagnostic technologies, viral respiratory pathogens are increasingly being identified as frequent etiologies of CAP. (medscape.com)
  • Over many years, OM-85, a lysate of 21 common bacterial respiratory pathogens, has been demonstrated to prevent respiratory recurrences in children. (biomedcentral.com)
Anti-inflammatory properties1
Pneumonia1
  • Small children who develop pneumonia and survive are at risk for developing lung problems in adulthood. (adam.com)
Penicillin1
  • Patients should only be treated with a macrolide if a penicillin or cephalosporin type drug is not an option. (medscape.com)
Airway5
  • Steroids may be used for airway compromise and symptomatic relief. (medscape.com)
  • Macrolides are postulated to reduce airway inflammation via several mechanisms. (ersjournals.com)
  • What is less clear is the evidence for a role of macrolides in the treatment of other chronic inflammatory airway diseases, e.g. cystic fibrosis, bronchiectasis, asthma, obliterative bronchiolitis, chronic obstructive pulmonary disease (COPD) and chronic rhinosinusitis. (ersjournals.com)
  • 5) The asthmatic rats have early airway responses and late airway response in high prevalence, (6) showing high levels of specific IgE on active immunization (6) and airway eosinophilia. (indexarticles.com)
  • The panel makes a conditional recommendation for interleukin (IL)-6 receptor antagonist monoclonal antibody treatment and high-flow nasal oxygen or continuous positive airway pressure in patients with hypoxaemic respiratory failure. (bvsalud.org)
Antibiotic3
  • However, in the pooled data, patients infected with MRMP had a longer febrile period (1.71 days), length of hospital stay (1.61 day), antibiotic drug courses (2.93 days), and defervescence time after macrolide treatment (2.04 days) compared with patients infected with MSMP. (cdc.gov)
  • [ 42 ] One study suggested that observation alone was most cost-effective strategy for GAS pharyngitis in children, and this strategy also had lower morbidity and mortality than antibiotic treatment groups. (medscape.com)
  • Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela. (lookformedical.com)
Tract infections2
Resistance1
  • In addition to many of the usual risks from antimicrobial therapy, macrolides also have clinically significant effects on cardiac conduction 21 and may be important promoters of antimicrobial resistance 22 . (ersjournals.com)
Clinically1
  • The investigators concluded that the measured milk concentrations of the steroid didn't pose a clinically vital risk to a nursing infant allergy symptoms red throat [url=https://energy.gov.bz/order/Marsone/]20 mg marsone purchase with mastercard[/url]. (ehd.org)
Infants2
  • Young infants aged 0-59days with signs of possible serious bacterial infection (pSBI) and age-matched controls provided blood and respiratory specimens that were analysed by blood culture and real-time PCR. (cdc.gov)
  • After the introduction of the Hib conjugate vaccine in the United States (US) in 1987 for children, and three years later in 1990 for infants, the annual incidence of invasive Hib disease in the pediatric population of age less than 5 years old has markedly decreased. (statpearls.com)
Chronic1
  • Patients with underlying diseases had much higher fatality rates than patients with no underlying diseases (10.5% for cardiovascular disease, 7.3% for diabetes, 6.3% for chronic respiratory disease, 6.0% for hypertension, 5.6% for cancer, and 0.9% for none) [ 4 ]. (springeropen.com)
20191
  • Introduction: Hospitalised patients with coronavirus disease 2019 (COVID-19) as a result of SARS-CoV-2 infection have a high mortality rate and frequently require noninvasive respiratory support or invasive ventilation. (bvsalud.org)
Prevalent1
  • The most prevalent area is Asia, where prevalence rates are 13.6%-100% ( 5 ). (cdc.gov)
Rhinosinusitis1
  • The prevalence of rhinosinusitis in the CF population borders on 100%, according to a combination of symptoms, physical and radiologic findings [ 3 - 5 ]. (hindawi.com)
Disease1
  • Gastroesophageal refl ux disease in children: How much we know? (aai.org.tr)
Severe1
  • On one hand, molecular studies have successfully identified effective, steroid-sparing agents for severe asthmatics. (medscape.com)
Alleviate2
  • In addition, pain medications such as NSAIDs or acetaminophen and steroids can alleviate the symptoms associated with GAS pharyngitis. (medscape.com)
  • Also,following extubation, a spell of cheerful exigencies nasal ventilation is often484 Cerebral Palsy Managementneeded to alleviate the children gain extensive independent respiratory function. (fosite.ru)
Significantly3
  • 48 hours after macrolide treatment was also significantly increased (OR 21.24), and an increased proportion of patients was changed to second-line treatment (OR 4.42). (cdc.gov)
  • In one study, patients concurrently treated with the macrolide troleandomycin were able to significantly reduce their total steroid dose without a significant decrease in asthma control 5 . (ersjournals.com)
  • Days of absence from day-care for children and working days lost by parents were significantly lower in the group with children treated with OM-85 for 3 months than in the placebo group (p = 0.007 and p = 0.004, respectively). (biomedcentral.com)
20181
  • 2018) Valoración de un nuevo ensayo quimioluminiscente en comparación con ELISA en la detección de IgG contra el virus de la hepatitis E. Revista de la Sociedad Andaluza de Microbiología y Parasitología Clínica. (vircell.com)
Pediatric1
  • This chapter provides an overview of babe fitness, an introduction to pediatric nursing, and a chin-wag of honest and permissible issues reciprocal to caring on account of children. (rmht-taximoto.fr)
Outcomes1
  • Macrolides, statins, glitazones, and phosphodiesterase-4 inhibitors have shown improvements in specific outcomes in small studies. (medscape.com)
Varies2
  • Nasal polyps may be identified on anterior rhinoscopy or nasal endoscopy in up to 86% of children with CF, but the frequency varies in different populations and study groups [ 10 - 16 ]. (hindawi.com)
  • The prevalence of myasthenia gravis i varies with location and ranges from 1.5-36.7 cases per 100,000 population. (patient.info)
Nasal1
  • In experts' opinion, the patients should also be considered as critical cases if they are suffering from high respiratory frequency (RR ≥ 30 bpm) and low oxygen index (arterial partial pressure of oxygen (PaO 2 )/fraction of inspired oxygen (FiO 2 ) ≤ 200 mmHg) under high-flow nasal cannula oxygen therapy (HFNC). (springeropen.com)
Widely1
  • Because of high oral bioavailability and once-daily formulation, macrolides have been widely used in outpatient settings. (cdc.gov)
Diffuse3
  • Untreated, the prognosis of diffuse panbronchiolitis is poor, with progressive deterioration of lung function, the development of diffuse bronchiectasis and death caused by respiratory failure. (ersjournals.com)
  • The role of macrolides in the treatment of diffuse panbronchiolitis is well established. (ersjournals.com)
  • A 43-year-old, human immunodeficiency syndrome-positive male presented with diffuse swelling in the right deltoid area. (symptoma.com)
Children's2
  • METHODS: This retrospective descriptive study was conducted on the recorded information of children with PFAPA syndrome referred to the children's specialty clinic of Imam Khomeini Hospital in Ilam city from March 2021 to February 2022. (bvsalud.org)
  • Professor Sly is a NHMRC Senior Principal Research Fellow and a paediatric respiratory physician with extensive research experience in respiratory physiology, developmental immunology and children's environmental health. (edu.au)
Estimates1
Immune1
Clinic1
  • In addition, there are new therapies under development for asthma that have good potential to reach the clinic in the next five years. (biomedcentral.com)
Symptoms1
  • Symptoms vary among children, adults, and older people. (adam.com)
High3
  • Officially, the rate of Autism amongst children has risen to as high as 1 in 50 , based on the glaring testimony of 100,000 parents in the US . (vaccineresistancemovement.org)
  • In the section on aspergillosis, the revised recommendations include the use of a room with high-efficiency particulate air filters rather than laminar airflow as the protective environment for allogeneic HSCT recipients and the use of high-efficiency respiratory-protection devices (e.g. (cdc.gov)
  • The greater effect observed in children prone to several respiratory episodes than in non-prone children seems to indicate that this lysate should be administered especially to children with a proven high susceptibility to RTIs. (biomedcentral.com)
Episodes1
  • Meyrin 2/Geneva, Switzerland) in reducing the number of new RTI episodes in 288 children aged 1 to 6 years with a history of recurrent RTIs and to compare the efficacy of the standard 3-month regimen with that of administration of OM-85 for 6 months during a 6-month study period. (biomedcentral.com)
METHODS1
  • METHODS: Five sites in Bangladesh, India and Pakistan enrolled mother-child pairs via population-based pregnancy surveillance by community health workers. (cdc.gov)
Commonly1
  • EM commonly occurs in young adults (between 20 and 40 years of age) and affects men more than women. (uspharmacist.com)
Influenza2
  • OM-85 was well tolerated and safe, even in children who received an influenza vaccination. (biomedcentral.com)
  • Finally, influenza vaccines are effective in no more than 80% of vaccinated children, with significant reduction of efficacy when mismatch between circulating vital strains and strains included in the vaccine occurs [ 7 ]. (biomedcentral.com)
Prevention2
  • This study was planned to further contribute to the evaluation of the role played by OM-85 in prevention of recurrent RTIs in children. (biomedcentral.com)
  • These guidelines update previous CDC recommendations for the diagnosis, treatment, and prevention of tuberculosis (TB) among adults and children coinfected with human immunodeficiency virus (HIV) in the United States. (cdc.gov)
Adults and children1
  • These guidelines update previous CDC recommendations for treating and preventing active tuberculosis (TB) among adults and children coinfected with human immunodeficiency virus (HIV) (1-3). (cdc.gov)
Lower1
  • Human beings are the sole natural host for this bacteria, and some NTHi strains are considered to be part of the normal flora of the upper and lower respiratory tract, the conjunctivae, and the genital tract. (statpearls.com)
Patients1
  • The majority of patients were male and in the age range of 3 - 4 years. (bvsalud.org)
Therapy2
  • The introduction of long-term macrolide therapy has resulted in dramatic improvements in survival, with 5-yr survival rates increasing from 63 to 92% 9 , 10 . (ersjournals.com)
  • Steroid therapy for TEN is 151559 272235 Systemic corticosteroids (Table 1). (noichuyenhay.com)
Rate2
Patient2
  • It is a report of disseminated bacillary angiomatosis (BA) in a 23-year-old female patient, who is HIV-positive and with fever, weight loss, hepatomegaly , ascites, and papular-nodular skin lesions. (symptoma.com)
  • This drug has triggered this rare condition called HLH in this patient who was treated for an upper respiratory tract infection. (ijtpr.com)
Onset1
  • Age at onset: child, or aged less than or more than 50 years. (patient.info)
Research1
  • 4th year University of Otago BMLSc Semester 2, 2020 research abstracts. (vircell.com)
Properties1
  • In mammals, the charm of L-arginine occurs through a one's own flesh of cationic amino acid transporters known as CATs (cationic amino acid transporters), the properties of which earmarks of that of the y + amino acid transport system. (fosite.ru)