Loading...
  • sequence
  • A repetitive sequence in the microdissected Y chromosome, RMY1, was isolated while screening repetitive sequences in the amplified Y chromosome. (oup.com)
  • Part of the nucleotide sequence shared a similarity to that of X-43.1, which was isolated from microdissected X chromosomes. (oup.com)
  • Since fluorescence in situ hybridization analysis with RMY1 demonstrated that RMY1 was localized at the ends of the chromosome, RMY1 may be a subtelomeric repetitive sequence. (oup.com)
  • background
  • The variations may create a genetic background for the susceptibility to Y-related spermatogenic impairment, although few data have been accumulated about the possible correlation between the Y-chromosome haplotype and the predisposition of men to spermatogenic failure. (bmj.com)
  • system
  • In the cichlid genus Tilapia and its close relatives, sex is determined by two pairs of chromosomes, one of which functions as an XY system and the other as ZW . (genetics.org)
  • clear
  • It is also clear that superimposed on the maternal meiotic chromosome segregation errors, there are a large number of mitotic errors taking place post-zygotically during the first few cell divisions in the embryo. (warwick.ac.uk)
  • probably
  • The Y-chromosome is an extreme outlier compared to modern groups, probably because of its heavy G2a domination, whereas the mtDNA from Treilles appears just like a normal and unexceptional Mediterranean-type population. (blogspot.nl)
  • On the contrary, the length of the W chromosome can fluctuate over short time scales, probably involving both shortening and elongation of non-coding regions. (royalsocietypublishing.org)
  • anaphase
  • In animal cells, chromosomes reach their highest compaction level in anaphase during segregation. (wikipedia.org)
  • Radiation increases the probability that dicentric chromosomes form after every mitotic event, creating physical bridges between them in anaphase and telophase. (wikipedia.org)
  • sequences
  • Moreover, lampbrush chromosomes are widely used for high-resolution mapping of DNA sequences and construction of detail cytological maps of individual chromosomes. (wikipedia.org)
  • This re-estimation of the age of the therian XY system is based on the finding that sequences that are on the X chromosomes of marsupials and eutherian mammals are present on the autosomes of platypus and birds. (wikipedia.org)
  • The older estimate was based on erroneous reports that the platypus X chromosomes contained these sequences. (wikipedia.org)
  • Thus, sequences not reachable by chromosome walking can be sequenced. (wikipedia.org)
  • Chromosome walking can be used from the new jump position (in either direction) to look for gene-like sequences, or additional jumps can be used to progress further along the chromosome. (wikipedia.org)
  • Drosophila
  • Scalenghe F, Turco E, Edstrom JE, Pirrotta V, Melli M.: Microdissection and cloning of DNA from a specific region of Drosophila melanogaster polytene chromosomes. (wikipedia.org)
  • organism
  • The X and Y chromosomes are thought to have evolved from a pair of identical chromosomes, termed autosomes , when an ancestral animal developed an allelic variation, a so-called "sex locus" - simply possessing this allele caused the organism to be male. (wikipedia.org)
  • This means that if an organism receives two copies of the balancer chromosome, one from the mother and one from the father, then the organism will not live. (wikipedia.org)
  • So any organism that is homozygous for that chromosome will not live to pass on its genes. (wikipedia.org)
  • This physical marker serves as a double check that you indeed have the heterozygous balancer chromosomes in the organism. (wikipedia.org)
  • In those organism the chromosome instead of remaining at specific position remain dispersed throughout the chromosome. (wikipedia.org)
  • avian
  • Platypus sex chromosomes have strong sequence similarity with the avian Z chromosome , (indicating close homology ), and the SRY gene so central to sex-determination in most other mammals is apparently not involved in platypus sex-determination. (wikipedia.org)
  • Amphibian and avian lampbrush chromosomes can be microsurgically isolated from oocyte nucleus (germinal vesicle) with either forceps or needles. (wikipedia.org)
  • translocation
  • The Philadelphia chromosome or Philadelphia translocation is a specific genetic abnormality in chromosome 22 of leukemia cancer cells (particularly chronic myeloid leukemia (CML) cells). (wikipedia.org)
  • Translocation results in an oncogenic BCR-ABL gene fusion that can be found on the shorter derivative 22 chromosome. (wikipedia.org)
  • This means there is a translocation between chromosome 9 and chromosome 22, with breaks happening in region (3), band (4), sub-band (1) of the long arm (q) of chromosome 9 and region (1), band (1), sub-band (2) of the long arm (q) of chromosome 22. (wikipedia.org)
  • Over time, genes that were beneficial for males and harmful to (or had no effect on) females either developed on the Y chromosome or were acquired through the process of translocation . (wikipedia.org)
  • The formation of dicentric chromosomes has been attributed to genetic processes, such as Robertsonian translocation and paracentric inversion. (wikipedia.org)
  • segregation
  • Normal cells make errors in chromosome segregation in 1% of cell divisions, whereas cells with CIN make these errors approximately 20% of cell divisions. (wikipedia.org)
  • Upon proper segregation, a complete set of chromatids ends up in each of two nuclei, and when cell division is completed, each DNA copy previously referred to as a chromatid is now called a chromosome. (wikipedia.org)
  • Improper chromosome segregation can result in aneuploid gametes having either too few or too many chromosomes. (wikipedia.org)
  • copies
  • Having an extra copy of this chromosome means that individuals have three copies of each of its genes instead of two, making it difficult for cells to properly control how much protein is made. (wikipedia.org)
  • The scientist uses these copies to study the DNA from the unusual region of the chromosome in question. (wikipedia.org)
  • rearrangement
  • Further information: As S. Sozhamannan and others have reported, Vibrio cholerae has a gene acquisition system located on its small chromosome as well as hot spots for DNA rearrangement. (nsf.gov)
  • Clarence Erwin M
  • She realized that the previous idea of Clarence Erwin McClung , that the X chromosome determines sex, was wrong and that sex determination is, in fact, due to the presence or absence of the Y chromosome. (wikipedia.org)
  • It was first suggested that the X chromosome was involved in sex determination by Clarence Erwin McClung in 1901 after comparing his work on locusts with Henking's and others. (wikipedia.org)
  • Inheritance
  • Aided by the rediscovery at the start of the 1900s of Gregor Mendel's earlier work, Boveri was able to point out the connection between the rules of inheritance and the behaviour of the chromosomes. (wikipedia.org)
  • In his famous textbook The Cell in Development and Heredity, Wilson linked together the independent work of Boveri and Sutton (both around 1902) by naming the chromosome theory of inheritance the Boveri-Sutton chromosome theory (the names are sometimes reversed). (wikipedia.org)
  • Luke Hutchison noticed that a number of possible ancestors on the X chromosome inheritance line at a given ancestral generation follows the Fibonacci sequence. (wikipedia.org)
  • protein
  • This gene is the ABL1 gene of chromosome 9 juxtaposed onto the BCR gene of chromosome 22, coding for a hybrid protein: a tyrosine kinase signalling protein that is "always on", causing the cell to divide uncontrollably. (wikipedia.org)
  • Chromosome seven is the home of genes associated with cystic fibrosis, deafness, several cancers and a protein that resists cancer drugs. (wired.com)
  • Dominant markers such as genes for green fluorescent protein or enzymes that make pigments allow researchers to easily recognize flies that carry the balancer chromosome. (wikipedia.org)
  • This marker can be actually associated with the DNA in the chromosome such as the Green Fluorescent Protein that fluoresces in ultraviolet light, or it can be an easily distinguishable physical characteristic. (wikipedia.org)
  • 2002
  • Morgan, G.T. (2002) Lampbrush chromosomes and associated bodies: new insights into principles of nuclear structure and function. (wikipedia.org)
  • vectors
  • The five overview and ten protocol chapters cover the engineering of chromosomes with extrachromosomal vectors and transposon systems, the manipulation of naturally occurred minichromosomes, the generation and engineering of synthetic artificial chromosomes, and the induced de novo platform artificial chromosome system. (springer.com)
  • In a series of experiments beginning in the mid-1880s, Theodor Boveri gave the definitive demonstration that chromosomes are the vectors of heredity. (wikipedia.org)
  • Histones
  • Since the binding of DNA by histones interferes with this access, cells have evolved specific mechanism to destabilize nucleosomes in chromosome regions that must be transcribed. (encyclopedia.com)