Complete ophthalmic examination including a Schirmer tear test, fluorescein staining of the cornea, tonometry, examination of the eyelids and surface of the eye with magnification (such as slit-lamp biomicroscopy), and detailed examination of the front and back portions of the eye. (petplace.com)
As fungal infections of the cornea are particularly prone to develop coincidentally with long-term local corticosteroid applications, fungal invasion should be suspected in any persistent corneal ulceration where a corticosteroid has been used or is in use. (nih.gov)
PURPOSE: Lumican is a major extracellular matrix (ECM) component in the cornea that is upregulated after injury and promotes corneal wound healing. (bvsalud.org)
Although he does have some residual neovascularization in the lower cornea, the lens provides an adequate vault over the surface and has succeeded in maintaining the corneal integrity. (sclerallens.com)
Ectatic corneal disease (ECD) comprises a group of disorders characterized by progressive thinning and protrusion of the cornea, leading to visual impairment. (contactlensupdate.com)
Systemic mepacrine can stain eyelids, conjunctiva, cornea and sclera yellow, and the basal layers of the conjunctival epithelium blue-gray. (entokey.com)
Epithelial cells2
HMWHA promotes the viability of human corneal epithelial cells (hTCEpi), while low MWHA (LMWHA), ultra-LMWHA (ULMWHA), and most forms of oxHA do not. (bvsalud.org)
The efficacy of the stapled peptides at promoting corneal wound healing was tested using a proliferation assay, an in vitro scratch assay using human corneal epithelial cells and an in vivo murine corneal debridement wound healing model. (bvsalud.org)
Epithelium1
Turner KPflugfelder SCJi ZFeuer WJStern M Interleukin-6 levels in the conjunctival epithelium of patients with dry eye disease treated with cyclosporine ophthalmic emulsion. (jamanetwork.com)
Irregular1
This lens modality may be considered for any other case involving irregular corneal curvature following surgery and reduced visual acuity. (sclerallens.com)
Conjunctiva1
This conjunctivoplasty surgery to correct Conjunctivochalasis typically involves resection of an ellipse-shaped segment of conjunctiva just inferior to the lower lid margin, and is usually followed either by suturing or amniotic membrane graft transplantation to close the wound. (wikipedia.org)
Ocular3
Ophthalmic Plastic and Reconstructive Surgery 1986;2:25-28 Fodor E, Barabino S, Montaldo E, Mingari MC, Rolando M. Qualitative evaluation of ocular surface inflammation in patients with conjunctivochalasisCurr Eye Res. (wikipedia.org)
Various ocular diseases and long-term use of topical corticosteroids have been known to cause corneal and scleral thinning. (nih.gov)
Therapeutic contact lenses for the treatment of corneal and ocular surface diseases: advances in extended and targeted drug delivery. (stanford.edu)
Exposure3
In pure aqueous tear deficiency dry eye patients, fluorescein stains in the interpalpebral exposure zone. (wikipedia.org)
In mechanical dry eye patients, fluorescein staining can be seen by pulling down the lower lid spread to the non-exposure zone. (wikipedia.org)
Emetine hydrochloride is somewhat unique in that somewhere between 4-10 hours after exposure in humans, the drug is probably secreted in the tears to give significant bilateral foreign-body sensation, epiphoria, photophobia, lid edema, blepharospasm and conjunctival hyperemia. (entokey.com)
Topical4
PRED FORTE ® (prednisolone acetate ophthalmic suspension, USP) 1% is a sterile, topical anti-inflammatory agent for ophthalmic use. (nih.gov)
Use of topical corticosteroids in the presence of thin corneal or scleral tissue may lead to perforation. (nih.gov)
Kunert KSTisdale ASStern MESmith JAGipson IK Analysis of topical cyclosporine treatment of patients with dry eye syndrome: effect on conjunctival lymphocytes. (jamanetwork.com)
Vitro1
In vitro studies using infra-/red light have not shown any useful impact on wound healing by activating cells located in deeper skin layers such as fibroblasts or stem cells [2] . (researchgate.net)
Proliferation1
Transcriptional coactivator Yes-associated protein (YAP) can promote the proliferation of multiple cancer cells, corneal endothelial cells, and vascular smooth muscle cells, which participate in angiogenesis. (molvis.org)
Vivo1
Finally, all native forms of HA and oxHA produced by HOCl promote in vivo corneal wound healing, while oxHA produced by H2O2 does not. (bvsalud.org)
Promotes1
Clinical use of photobiomodulation (PBM) therapy, promotes surgical wound closure [4]. (researchgate.net)
Surgical1
For administration by the physician at the end of the ophthalmic surgical procedure. (pdr.net)
Therapeutic1
The identification of HA/HC complexes in the LSCN could serve as a new therapeutic avenue for treating corneal pathology. (bvsalud.org)
Acute1
In this paper, we review and present our new data of LED treatment on cells grown in culture, on ischemic and diabetic wounds in rat models, and on acute and chronic wounds in humans. (researchgate.net)
Scratch1
A corneal ulcer or scratch can also cause reflex pain and spasm of the iris inside of the eye. (petplace.com)
Glaucoma3
Elliot's first book, Sclero-corneal Trephining in the Operative Treatment of Glaucoma, appeared in 1913 after he completed 900 cases, and the procedure received worldwide publicity. (medscape.com)
Elliot followed up his first book with annual progress summaries on glaucoma in the Ophthalmic Yearbooks of 1913-1916 and a short book, Glaucoma: A Handbook for the General Practitioner, in 1917. (medscape.com)
This rarely causes significant scarring with permanent corneal opacities with or without iritis and secondary glaucoma. (entokey.com)
Diseases1
Many corneal diseases can lead to vision loss affecting the lives of people around the world. (stanford.edu)
Efficacy2
Sall KStevenson ODMundorf TKReis BL Two multicenter, randomized studies of the efficacy and safety of cyclosporine ophthalmic emulsion in moderate to severe dry eye disease. (jamanetwork.com)
Stevenson DTauber JReis BL Efficacy and safety of cyclosporine A ophthalmic emulsion in the treatment of moderate to severe dry eye disease: a dose-ranging, randomized trial, The Cyclosporine A Group. (jamanetwork.com)
Inferior2
The test can be done as follows: Apply 5 μl of fluorescein to the base of the inferior fornix, maximally deplete the lower tear meniscus by a capillary tube or Weckcel sponge, and then monitor the recovery of the tear meniscus height with or without blinking. (wikipedia.org)
On the left eye, however, an adequate fit could not be obtained because there was progressive fibrovascular growth over the inferior temporal ICRS with lens touch and resulting fluorescein staining at every visit despite consequent steepening of the lens. (sclerallens.com)
Patients2
Diagram and scale used to measure intensity of corneal staining in patients with dry eye disease. (jamanetwork.com)
A study by Williamson et al have reported that the overall incidence of fungi was 2.9% in patients with healthy conjunctival flora. (eophtha.com)
Tears1
Most commonly used in this category is carboxymethylcellulose, which increases the viscosity of tears and has mucoadhesive properties that allow for longer corneal coverage, explains Cecilia Koetting, OD, of Norfolk, VA. (reviewofoptometry.com)
Secondary ectasias, on the other hand, refer to corneal shape changes caused by external factors, such as corneal surgery or trauma, with no underlying ectatic propensity existing, and would be considered "thinning disorders" as opposed to a primary ECD. (contactlensupdate.com)
Suspension2
The initial prescription and renewal of the medication order beyond 20 milliliters of PRED FORTE suspension should be made by a physician only after examination of the patient with the aid of magnification, such as slit lamp biomicroscopy, and, where appropriate, fluorescein staining. (nih.gov)
Apply ophthalmic solution or suspension topically to the eye. (pdr.net)
Surgery2
If discomfort persists after standard dry eye treatment and anti-inflammatory therapy, surgery may be undertaken to remove the conjunctival folds and restore a smooth tear film. (wikipedia.org)
Like many other ophthalmic procedures, strabismus surgery is very safe and effective, but complications can occur and need to be diagnosed and treated early to optimize post-operative outcome. (eyewiki.org)
Treatments1
Several reviews have published evidence on the effectiveness of PBM treatments in mitigating inflammation and promoting wound healing [2] . (researchgate.net)
Treatment1
New devices have demonstrated significant results for the treatment of medical conditions, including mild-to-moderate acne vulgaris, wound healing, psoriasis, squamous cell carcinoma in situ (Bowen's disease), basal cell carcinoma, actinic keratosis, and cosmetic applications. (researchgate.net)
Promote1
Light-emitting diodes (LED), originally developed for NASA plant growth experiments in space show promise for delivering light deep into tissues of the body to promote wound healing and human tissue growth. (researchgate.net)
Drug1
Ophthalmic drug delivery has always been a major challenge in the medical sciences. (stanford.edu)
Shown2
We have recently shown that peptides designed based on the 13 C-terminal amino acids of lumican (LumC13 and LumC13C-A) are able to recapitulate the effects of lumican on promoting corneal wound healing. (bvsalud.org)
It has even been shown to accelerate wound healing post-op. 2 The unique multi-dose pump does not allow air to penetrate the interior, keeping it safe for its six-month lifespan (once opened). (reviewofcontactlenses.com)
Pain1
A specific ophthalmic medication, called atropine , is used to treat this type of pain. (petplace.com)
Effects1
The purpose of this study was to assess the effects of hyperbaric oxygen (HBO) and near-infrared light therapy on wound healing. (researchgate.net)
Size1
Wound size decreased up to 36% in conjunction with HBO in ischemic rat models. (researchgate.net)
Expression2
Proliferating cell nuclear antigen (PCNA) expression in CNV mice without or with YAP siRNA intravitreal injection and the colocalization of PCNA and CD31 were measured with western blotting and immunofluorescent double staining, respectively. (molvis.org)
Furthermore, the differential expression of key compounds in different corneal cell types were determined with single-cell RNA sequencing. (bvsalud.org)
We believe that the use of NASA LED for light therapy alone, and in conjunction with hyperbaric oxygen, will greatly enhance the natural wound healing process, and more quickly return the patient to a preinjury/illness level of activity. (researchgate.net)
Visual1
Ophthalmic diagnosis is established firstly by listening to the details of the patient's complaint, both in terms of visual symptoms and visual function, before examination and investigation. (southsudanmedicaljournal.com)