• ExoTEST is a patented double sandwich ELISA assay for quantitative and qualitative analysis of exosomes. (immpact-international.org)
  • ExoTEST consists of ELISA plates pre-coated with patented panexosome antibodies that allow specific capture of exosomes from a variety of biological samples, including cell culture supernatants and human biological fluids. (immpact-international.org)
  • In concept, Luminex assays are numerous ELISA assays on a bead. (magazinexu.com)
  • Thus, through 96-well or 364-well plates, Luminex ELISA multiplex assays provide higher throughput and density. (magazinexu.com)
  • Luminex ELISA assays produce accurate results similar to traditional ELISA assays. (magazinexu.com)
  • Besides, these results are as accurate and reliable as conventional ELISA assays. (magazinexu.com)
  • Until now the standard procedure to validate antibodies for IP couples the IP assay to immunoblotting (IP/IB), a procedure that is challenging to scale to high-throughput analysis [ 10 ]. (biomedcentral.com)
  • Luminex assays can be conjugated with receptors, antibodies, and peptides, and thus their applications can be extended to protein expression and gene expression profiling, HLA testing, and much more. (magazinexu.com)
  • You already know about our antibodies, but did you know we use those same antibodies in our assay kits? (abcam.com)
  • We offer high quality native and recombinant antigens, enzymes, and other proteins to be used in a wide range of life science research and diagnostics applications, such as calibrator and control products, serological immunoassays, and biological activity assays. (medixbiochemica.com)
  • Compared to conventional immunoassays, Luminex assays provide a wide dynamic range. (magazinexu.com)
  • Studies in this area led to the identification of multiple bioluminescent proteins and enzyme systems, some of which have found direct applications in biological research (2). (neb.com)
  • The mystery and the potential biological significance of these unknown genes is enhanced by many of them being well conserved, and many of them being completely unrelated to known proteins and thus lacking clues to their function. (biorxiv.org)
  • Myosin motor proteins orchestrate a wide range of kinetic events within a cell. (cytoskeleton.com)
  • Naturally secreted from the deep sea copepod Gaussia princeps (3) (Figure 1), Gaussia Luciferase (GLuc) was first used in a sensitive analytical assay in 2002 (4) and later commercialized by NEB for expression in mammalian cells. (neb.com)
  • Since the introduction of the first bioluminescent dual-luciferase assay in 1995, this approach has been used in countless studies to advance our scientific understanding of cellular gene regulation. (promegaconnections.com)
  • Luciferase assays are useful tools for studying a wide range of biological questions. (promegaconnections.com)
  • By combining allele-specific amplification and hydrolysis probe detection, qBiomarker Somatic Mutation real-time PCR assays have been developed which can detect as few as 1% somatic mutations in the background of wild-type genomic DNA. (qiagen.com)
  • Linear detection range 0.12 µM (0.78 µg/dL) to 10 µM (65 µg/dL) zinc in 96-well assay format. (immpact-international.org)
  • By contrast, the QIAseq Library Quant Array was able to quantify both libraries (see figure The QIAseq Library Quant System enables quantification of libraries with concentrations below the detection limit of conventional methods The QIAseq Library Quant Array's high sensitivity and broad dynamic range enable the quantification of both the NGS-L1 and NGS-L2 libraries [A]. By contrast, Agilent's High Sensitivity DNA Kit (for use with the Agilent 2100 BioAnalyzer) quantified only the NGS-L1 library; with this kit, the NGS-L2 concentration was too low for quantification [B]. "> QIAseq Library Quant System enables quantification of libraries with concentrations below the detection limit of conventional methods ). (qiagen.com)
  • The array format provides this standard in five predispensed, sequential 10-fold dilutions mixed with a PCR primer assay in triplicate, ensuring that your sample library will fall within the detection range of the array (see figure Principle of the QIAseq Library Quant System The serial dilutions of the DNA standard (5 sequential 10-fold dilutions) generate a standard curve. The sample library should fall within the standard curve. "> Principle of QIAseq Library Quant System ). (qiagen.com)
  • Sensitivity of an assay dictates the detection of the target within the dynamic range of the assay with the caveat that the lower limit of detection could vary marginally from batch to batch. (genengnews.com)
  • Both assay format and detection technology play major roles in sensitivity. (genengnews.com)
  • The dynamic range of an assay defines both the lower and upper limits of detection. (genengnews.com)
  • With dye-based detection such as SYBR Green I, primer dimers also affect assay specificity because the nonspecific DNA-binding dye will bind to the primers and be detected along with the desired product. (sigmaaldrich.com)
  • Researchers leverage PerkinElmer's chemagen offerings to simplify their workflows for a wide range of next generation sequencing and PCR applications in the field of human genetics/biobanking, HLA typing, pathogen detection, and viral identification. (technologynetworks.com)
  • Taking advantage of the good conductivity and large electrode area of the MWCNT arrays, this electrochemical DNA sensor achieved a dynamic range from 1.0 × 10-12 M to 1.0 × 10-8 M with a minimal detection limit of 6.4 × 10-13 M. In addition, this proposed DNA biosensor exhibited high sensitivity, selectivity, and stability, which may be useful for the trace analysis of the MDR1 gene in complex samples. (bvsalud.org)
  • Thus, we successfully achieved an ultrahigh sensitivity, extremely wide dynamic range, great simplicity, and strong anti-interference detection of ATP. (bvsalud.org)
  • In particular ExoTEST is a successful platform for exosomes quantification and characterization from small amount of human biological fluids or cell media and it may be exploited to identify exosomes released by cancer cells in the plasma and urine of tumor patients in various disease conditions. (immpact-international.org)
  • To facilitate the accurate quantification of total bile acids in serum and plasma, the 5th Generation Total Bile Acids Assay has emerged as a reliable and advanced diagnostic tool. (randox.com)
  • The QIAseq Library Quant System is available in both a tube and an array format, and is optimized with QIAseq qPCR SYBR ® Green Mastermixes to provide superior sensitivity and a wide dynamic range. (qiagen.com)
  • The array format workflow (see figure QIAseq Library Quant Array workflow Each sample DNA library is combined with QIAseq qPCR SYBR ® Green Mastermix, aliquoted in technical triplicate across the QIAseq Library Quant Array, and analyzed with qPCR. Raw C T values are copied into the data analysis Excel template, and the software automatically calculates the library concentration or dilution factor. "> QIAseq Library Quant Array workflow ) begins with two tenfold dilutions of the sample library, to ensure that its concentration falls within the range of the serially diluted standards. (qiagen.com)
  • An assay that has been designed such that all desirable design criteria were met ( PCR/qPCR/dPCR Assay Design ) is likely to perform well under a wide range of conditions. (sigmaaldrich.com)
  • The primer design can be reviewed with respect to the assay design guidance provided in PCR/qPCR/dPCR Assay Design . (sigmaaldrich.com)
  • BioAssay Systems' QuantiChromTM Alkaline Phosphatase Assay Kit is designed to measure ALP activity directly in biological samples without pretreatment. (gentaur.be)
  • A new study, "The validity, stability, and utility of measuring uric acid in saliva," published in Biomarkers in Medicine, used the Salimetrics Salivary Uric Acid Assay Kit as part of a longitudinal study to better understand the biological value of measuring uric acid in saliva samples. (salimetrics.com)
  • Develop, optimize, establish and conduct a wide range of biological, molecular and biochemical assays. (nature.com)
  • The factors that need to be considered include: selection of the most appropriate assay technologies, reading modalities, and experimental models (biochemical, cellular, or animal). (genengnews.com)
  • Biochemical assays are simpler to execute than their cellular counterparts and offer better consistency. (genengnews.com)
  • Hence, it is desirable to start with a biochemical assay followed by a cell-based assay to corroborate results in a physiological context (that is, to provide orthogonal validation). (genengnews.com)
  • SAGIAN Automated Assay Optimization (AAO) software is now allowing scientists to import designed experiments that are translated into corresponding Biomek FX methods. (qualitydigest.com)
  • Optimization of experimental assay design is crucial for the overall success of any drug discovery initiative. (genengnews.com)
  • Assay optimization and validation are essential, even when using assays that have been predesigned and commercially obtained. (sigmaaldrich.com)
  • Optimization is required to ensure that the assay is as sensitive as is required and that it is specific to the target of interest. (sigmaaldrich.com)
  • Assays requiring high specificity are particularly vulnerable when performed without optimization and adequate controls. (sigmaaldrich.com)
  • Since it is usual to run the assay on a selected instrument and under standard buffer conditions, most optimization procedures are focussed on modification of primer binding kinetics using primer concentration or annealing temperature (T a )/melting temperature (T m ). (sigmaaldrich.com)
  • The immunoprecipitation (IP) assay is a valuable molecular biology tool applied across a breadth of fields. (biomedcentral.com)
  • Consequently, small-molecule drug discovery usually involves an iterative process of molecular design, chemical synthesis, biological assay and data analysis feeding directly into the next cycle, but this process always needs a chemical starting point. (ddw-online.com)
  • There are a number of factors that can be altered to obtain optimum assay performance and thereby lead to higher molecular sensitivity, specificity and precision. (sigmaaldrich.com)
  • The information lost in OFAT designs may significantly reduce assay quality and robustness. (qualitydigest.com)
  • This process has already been undertaken we have examined critically the relevance to several years ago for the local lymph node assay humans, the robustness and the reliability of (LLNA) (2). (cdc.gov)
  • For the last ten years the NBA team were responsible for providing and reporting on blood and urine biomarker data for the UK National Diet and Nutrition Survey, and also in support of a wide range of nutrition studies and surveys in UK and worldwide. (kcl.ac.uk)
  • Biological Assays and Biomarker Discovery - Researchers employ a wide range of assays to measure the biological effects of potential drugs. (afroclub.net)
  • The finding suggests that salivary uric acid could serve as a biomarker for a wide range of potential conditions and disease states," writes principal investigator, Jenna Riis, Ph.D., a researcher at the Institute for Interdisciplinary Salivary Bioscience Research, University of California at Irvine. (salimetrics.com)
  • The Toolkit was revised to allow researchers to select self-or interviewer administration when creating the data collection worksheets and ranges of specimens necessary to run biological assays has been added to the Toolkit. (rti.org)
  • These technologies allow researchers to automate and improve the efficiency of their workflows across liquid handling, assays, big data and informatics processing, high content imaging and nucleic acid extraction. (technologynetworks.com)
  • LANCE® Ultra TR-FRET Assay Kits: With over 60 new, easy-to-use kits for oncology, immunology, metabolic, neuro and biotherapeutic targets, these innovative assays enable researchers performing drug discovery to achieve highly sensitive and reliable results in an extremely short amount of time. (technologynetworks.com)
  • Using the LANCE Ultra kits' unique combination of ULight Acceptor and Europium Eu chelate donor pairs, researchers can perform a wider variety of highly sensitive, automation friendly assays to speed and simplify the screening process. (technologynetworks.com)
  • Researchers employ several techniques for evaluating cytokines in biological samples. (magazinexu.com)
  • Researchers can customize study probes on assay panels and develop custom Luminex assays for individual research needs. (magazinexu.com)
  • To navigate this intricate landscape successfully, pharmaceutical companies and researchers rely on a wide range of drug discovery services. (afroclub.net)
  • Salimetrics assays have been successfully supporting researchers for over 20 years, and the Salivary Uric Acid Assay maintains the high-quality performance characteristics that are a staple of Salimetrics' premium salivary assays. (salimetrics.com)
  • Claims relating to the performance of assays should be verified under the conditions of the study, including test samples, specific reagents and the instrument of choice. (sigmaaldrich.com)
  • However, all assays have a set of optimal conditions and these are dependent on the instrument, selected reagents (buffer conditions), primer concentration and/or annealing temperature (T a ), magnesium concentration and even ramp rate. (sigmaaldrich.com)
  • Assay technologies may not always be compatible with particular matrices, which can cause interference. (genengnews.com)
  • Additionally, for complex biological matrices, antibody selection can be challenging since protein targets secreted from cells into cell culture media or serum may be cleaved or modified, altering epitope recognition-hence the benefit of using protease cocktail inhibitors. (genengnews.com)
  • Thus, the Luminex assay expands the reach of customers in evaluating cytokines in complex biological matrices. (magazinexu.com)
  • The DR-CALUX assay uses genetically modified animal cells to detect, specifically and quantitatively, toxicity caused by exposure to dioxin and dioxin-like PCBs in a wide range of matrices, including food. (safefood.net)
  • For example, hemoglobin found in serum, plasma, or blood exhibits wide absorbance across the visible light spectrum, namely between 350 and 600 nm. (genengnews.com)
  • They can analyze a wide range of biological samples such as saliva, sputum, urine, cell and tissue lysate, plasma, and serum, making them a crucial screening modality. (magazinexu.com)
  • Direct Assays: ALP activity in serum, plasma and other sources. (gentaur.be)
  • Serum, plasma (no EDTA/citrate, ideally unhemolyzed) and cell culture media can be assayed directly. (gentaur.be)
  • Wash-based assays can be used to circumvent interference caused by highly complex sample types, as molecules within the matrix that contribute to interference are washed away. (genengnews.com)
  • The goal is to identify molecules that exhibit the desired biological activity, which can serve as a starting point for drug development. (afroclub.net)
  • Contains chemical molecules and their activities against biological assays. (mtu.edu)
  • In the biological sciences the suffix -omics is used to refer to the study of large sets of biological molecules. (who.int)
  • Through various omic technologies it is now possible to interrogate large sets of biological molecules. (who.int)
  • ATCC also serves to set standards for biological reagent and assay quality. (wikipedia.org)
  • Similarly, when multiple targets are to be detected simultaneously in multiplex reactions, assay conditions must be optimized to detect all targets equally. (sigmaaldrich.com)
  • Hence, Luminex ELISAs can multiplex upto 100 analytes in a single assay well. (magazinexu.com)
  • The assay can multiplex upto 100 tests in a single run and run upto 1000 study samples every day. (magazinexu.com)
  • Find or custom design the right target-specific assays and panels to research your biological targets of interest. (qiagen.com)
  • These methods may also incorporate simple calculated properties, for example the so-called 'Rule of 5' (5) to ensure libraries stay within sufficiently druglike areas of chemical space as well as existing structure activity relationship data describing the interaction of the chemical matter with the principle biological target, as well as related targets. (ddw-online.com)
  • l (light path, cm) is 1 cm for cuvette, and calculated for 96-well assay from the Calibrator, l = (ODCALIBRATOR - ODH2O)/(ε ⋅ c). (gentaur.be)
  • These stringently quality controlled filaments provide highly reliable and reproducible results in assays that require actin filament substrates. (cytoskeleton.com)
  • Using these PAFs in assays depending on filaments gives very reproducible results. (cytoskeleton.com)
  • Using mathematical models, they're evaluating experimental parameters in order to optimize assay conditions. (qualitydigest.com)
  • ATCC, along with the Centers for Disease Control, sold or sent biological samples of anthrax, West Nile virus and botulism to Iraq up until 1989, which Iraq claimed it needed for medical research. (wikipedia.org)
  • All NIH Institutes and Centers participate in NIH-wide initiatives. (nih.gov)
  • National laboratories used WHO reference assays developed by the United States Centers for Disease Control and Prevention, an RSV subtyping assay developed by the Victorian Infectious Diseases Reference Laboratory (Australia), or other in-house or commercial assays already in use at their laboratories. (cdc.gov)
  • Phenotypic cellular assay models more accurately reflect the complex biology of disease, allows for multiparametric measurement of ex vivo or in vivo events, and enables the characterization of intractable target(s). (genengnews.com)
  • Several enzymes with higher catalytic efficiencies on a wider range of model substrates than previously characterized fungal GEs were identified. (proteopedia.org)
  • Contains extensive information from a wide range of chemistry journals. (mtu.edu)
  • After working as a Lateral Flow Assay R&D manager in Madrid (Spain), she joined Springer in 2016 in the Heidelberg office (Germany), managing a portfolio of chemistry book and journal titles. (springer.com)
  • Since 2019, she is a member of the global chemistry book team, and she has been publishing a wide range of book types including monographs, edited volumes, review series, textbooks and major reference in the fields of Biochemistry, Biotechnology, Medicinal Chemistry, Environmental Chemistry & Food Chemistry. (springer.com)
  • Floor-to-floor heights should permit space for routing future utilities for a range of scientific tasks , from wet chemistry and bioprocess experiments to physical/electrical and computational science. (ecotec-me.com)
  • Procedure: Assay takes 30 min. (immpact-international.org)
  • The standard assay couples IP to immunoblotting (IP/IB), a procedure severely limited as it is not easily scaled for high-throughput analysis. (biomedcentral.com)
  • ATCC's collections include a wide range of biological materials for research, including cell lines, microorganisms and bioproducts. (wikipedia.org)
  • qBiomarker Somatic Mutation PCR Arrays are translational research tools that allow rapid and accurate profiling of the somatic mutation status for important genes related to a biological pathway or disease. (qiagen.com)
  • The immunoprecipitation assay (IP) is an important tool used in academic and industrial research labs for applications such as targeted protein purification, protein concentration, analysis of protein-protein interactions, identification/analysis of protein complexes and analysis of protein/DNA interactions using chromatin IP (ChIP). (biomedcentral.com)
  • October 13, 2006 - See Notice NOT-OD-07-006, This notice is to inform potential applicants that investigators from the NIH Intramural Research Program (IRP) will be eligible to participate in the NIH-wide Genes and Environment Initiative (GEI). (nih.gov)
  • Validation provides the data required to justify the continued use of the assay in further research projects 1 . (sigmaaldrich.com)
  • This bias in biological research toward the previously studied appears to reflect several linked factors. (biorxiv.org)
  • When you pair the robust performance characteristics of Salimetrics' Salivary Uric Acid Assay with the stability of uric acid in saliva enabling the potential for at home collections, the research applications are near limitless. (salimetrics.com)
  • Emerging research is also beginning to link salivary uric acid's role as part of the biological response to stress. (salimetrics.com)
  • Based on this research, Dr. Riis notes, "Salivary uric acid has widespread potential in biobehavioral and health research, and there is a critical need to further understand the complex biological relationships that connect uric acid with health and well-being. (salimetrics.com)
  • Accordingly, our research program is focused on genomic tumor biology and the subsequent functional elucidation of biological mechanisms. (lu.se)
  • To evaluate the use of salivary ChE as a biological monitor for OP insecticide exposure, a modified Ellman assay in conjunction with a pharmacodynamic model was used to characterize salivary ChE in adult male Sprague-Dawley rats. (cdc.gov)
  • Luminex assays can effortlessly evaluate and measure critical biological elements in study samples. (magazinexu.com)
  • Whenever primer dimer products are produced and amplified, they divert reaction components away from synthesis of the desired product, thereby reducing assay efficiency and sensitivity. (sigmaaldrich.com)
  • The variations in transfection efficiency will equally affect both the experimental and control reporters so the ratio of activity in dual-reporter assays will normalize the data. (promegaconnections.com)
  • The focus of her work has been developing and optimizing assay and specimen collection methods suitable for large-scale biological data collection in non-clinical settings. (kcl.ac.uk)
  • The technique is suitable for a wide array of assembly of micro- and nanoscale objects, and useful for electronic devices, and biological applications. (umich.edu)
  • To do this, we will perform genome-wide siRNA screens on MITF-high and -low melanoma cells in combination with genomic analysis and suitable functional assays. (lu.se)
  • Operetta® CLS™ High-Content Analysis System & Columbus™ Software: The Operetta CLS system enables scientists to gain deep biological insight into disease from common assays and complex applications using advanced cellular models, and to identify even subtle phenotypic changes through sensitive imaging and intuitive data analysis. (technologynetworks.com)
  • Promega dual-reporter assays are designed for same-well multiplexing so there is no chance of variations creeping into your data due to unequal splitting of the cellular lysate to measure two separate reporter activities. (promegaconnections.com)
  • A recent study using Salimetrics Salivary Uric Acid Assay found strong support for the validity, stability, and utility of measuring uric acid in saliva. (salimetrics.com)
  • ATCC-produced standards are used in a wide range of applications including the development of therapeutic and diagnostic medical products, food safety, water and environmental testing, and to obtain actionable forensic information. (wikipedia.org)
  • LUMIER was successfully applied to a range of applications but, to our knowledge, is still the only high-throughput option to classical IP/WB. (biomedcentral.com)
  • These features make these luciferases ideal for repeated assays, sensitive measurements in miniaturized assays and single cell applications. (neb.com)
  • With straightforward protocols for a wide range of biological assays, 歫观皈罗单轧仳有哥亚 's applications are utilized across life science industries all over the world. (cedii.net)
  • A network-wide data use agreement was developed to facilitate data sharing and collaboration. (rti.org)
  • The objective of this article is to inform about efforts to design and implement a data model that can parametrically describe and store information about a wide range of ecotoxicological tests and bioindication methods used in Ecological Risk Assessment (EcoRA). (muni.cz)
  • Collectively, these factors are known to influence data quality, biological relevance, and therapeutic predictability, which will ultimately impact the success of entire preclinical drug development efforts. (genengnews.com)
  • The purpose of this funding opportunity is to provide support for investigative groups to conduct genome-wide association (GWA) genotyping and/or replication studies using data and samples from human subjects on whom information is available for conditions/traits of public health importance and relevant environmental exposures. (nih.gov)
  • It includes support for sharing the samples and data and analyzing the resulting data as part of the NIH-wide Genes and Environment Initiative (GEI). (nih.gov)
  • Chemoinformatics and Computational Modeling - Computational tools and algorithms are used to analyze data, predict compound properties, and model biological processes. (afroclub.net)
  • 1974. Biological handbooks: Biology data book. (cdc.gov)
  • There are good arguments it has become apparent that in addition to hazard that the standard against which new methods are identification, the dose-response data available being judged is much higher than those in place from the LLNA also permit further characteriza- when existing assays were adopted. (cdc.gov)
  • The Working Solution is prepared by mixing for each 96-well assay, 200 µL Assay Buffer, 5 µL Mg Acetate (final 5 mM) and 2 µL pNPP liquid substrate (10 mM). (gentaur.be)
  • Melanoma is a disease that demonstrates a wide range of clinical behavior from relatively indolent to aggressive metastatic disease. (lu.se)
  • We believe that increased biological understanding of the two main melanoma states will help us to identify novel therapeutic options. (lu.se)
  • Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation. (lu.se)
  • We propose that integrated testing strategies should comprise complementary assays, providing measurements of a wide range of mechanistic events, to perform well-educated risk assessments based on weight of evidence. (lu.se)
  • Can be readily automated as a high-throughput assay for thousands of samples per day. (immpact-international.org)
  • Low interference in biological samples. (immpact-international.org)
  • Since you cannot be 100% sure that your solvent of choice is inert, you can go for DMSO, which is widely used to dissolve extracts/samples in most biological assays (mainly because it is considered inert). (bitesizebio.com)
  • Biological samples are always limited. (magazinexu.com)
  • Luminex assays are indeed crucial in identifying and quantifying cytokines from study samples. (magazinexu.com)
  • The overall conclusion demonstrated salivary uric acid's potential as a strong indicator of systemic uric acid activity and carried a high measurement validity and relative stability as a biological sample within the samples collected. (salimetrics.com)
  • Note: (1) if sample ALP activity exceeds 800 IU/L, dilute samples in saline and repeat the assay, multiply the result by the dilution factor. (gentaur.be)
  • A trial on the quantitative risk assessment of man-made mineral fibers by the rat intraperitoneal administration assay using the JFM standard fibrous samples. (cdc.gov)
  • In the previous article in this series, we have discussed the details of the CAM assay as a method of studying anti-angiogenic activity . (bitesizebio.com)
  • This involves screening of wide range of drug libraries of chemicals for a particular biological activity in throughput screening assays. (acumenresearchandconsulting.com)
  • This assay detects dioxins based on their specific biological activity towards genetically modified living cells through light generation from the recombinant cells. (safefood.net)
  • BK051 and BK054 ) can therefore be used as a test for the biological activity of AKF99 (Fig. 1). (cytoskeleton.com)
  • Reactions were performed using the Cytophos Endpoint Assay Kit (Ca t. (cytoskeleton.com)
  • Assay technologies relying on excitation or emission at these wavelengths will be prone to interference. (genengnews.com)
  • Ideally, a plate should be equilibrated to ambient room temperature before proceeding to the reporter assay. (promegaconnections.com)
  • Assays can be executed at room temperature or 37°C. (gentaur.be)
  • In addition, B. dendrobatidis strains isolated from across the world have low levels of genetic diversity, consistent with a pathogen that has recently undergone rapid range expansion ( 4 , 5 ). (cdc.gov)
  • Validation of primer design is particularly important when adopting primers from a previous publication or using a commercially supplied assay. (sigmaaldrich.com)
  • This assay is based on a kinetic reaction. (gentaur.be)
  • Supplement to documentation of the threshold limit values and biological exposure indices. (cdc.gov)
  • The aim of this work is to complement existing EcoRA decision-support tools with a web-based engine for storing and searching biological tests and methods used in EcoRA as there is currently no similar informational source available on the Internet. (muni.cz)
  • This RFA is developed as part of the NIH-wide Genes and Environment Initiative. (nih.gov)
  • This light emission can be easily detected and measured, making luciferases ideal for the development of biological reporter systems. (neb.com)
  • Transient transfection is often used to perform reporter assays. (promegaconnections.com)
  • Here are seven ways in which dual-reporter assays help you avoid misinterpreting results. (promegaconnections.com)
  • Often, reporter assays look at the dose response curve of a particular compound with regard to gene expression. (promegaconnections.com)
  • With this ability, engineers would be able to more efficiently manufacture and assemble photonic crystals, filtration devices and biological assays, create more sensitive sensing devices, and much more. (umich.edu)
  • The requirement is to develop high-quality, robust assays that work across a wide range of biological conditions. (qualitydigest.com)
  • The sensitivity and dynamic range of the QIAseq Library Quant System were compared against Agilent's High Sensitivity DNA Kit, using two NGS libraries of differing concentrations. (qiagen.com)
  • In this article, we discuss the dos and don'ts of the CAM assay, shedding light on how to avoid the high chances of contamination that the assay presents, tricks on how to handle the eggs and the embryos without causing damage, and how to avoid confusion when handling the huge sample size. (bitesizebio.com)
  • Combined with the high catalytic oxidation ability of DNAzyme, this ECL sensor can realize ATP assay as low as 1.4 fmol without other complicated exonuclease amplification strategies. (bvsalud.org)
  • Because the ECL intensity of Ru(bpy)32+ is sensitively affected by the antibody-antigen insulator, a preferable linear dependence was obtained in the concentration range of CEA from 1 pg·mL-1 to 350 ng·mL-1 with high selectivity (LOD of 0.3 pg·mL-1, S/N = 3). (bvsalud.org)
  • The advantages of luminescence, over fluorescence, include the absence of background, the amplification of signal and a high dynamic range that spans many orders of magnitude. (neb.com)
  • The Luminex assay offers both high-throughput and high-density sample analysis. (magazinexu.com)
  • In addition, there was a wide range of adaptive ability levels in children with autism in our study, including in those with low, average, or high cognitive scores. (cdc.gov)
  • For example, as shown in Figure 1A , the dynamic range for quantitating tumor necrosis factor-α (TNFα) varies by at least a log across different technologies. (genengnews.com)
  • Extended dynamic range at both the lower and upper ends. (abcam.com)
  • No matter how carefully you perform the CAM assay, contamination, and/or mortality of embryos is inevitable. (bitesizebio.com)
  • Serious' effects are those that evoke failure in a biological system and can lead to morbidity or mortality (e.g., acute respiratory distress or death). (cdc.gov)
  • T cruzi infection in humans occurs in a spotty distribution throughout the range of the sylvatic cycle. (medscape.com)