8. Melchers, F.: Biosynthesis, transport and secretion of immunoglobulin in plasma cells. (uni-mainz.de)
I am a plant cell biologist and protein biochemist at Oxford Brookes University with expertise in the structure and function of the plant endoplasmic reticulum (ER), membrane proteins and auxin biosynthesis using biochemical techniques as well as high-resolution live cell imaging. (brookes.ac.uk)
For instance, the transformation of plants with a yeast-derived invertase targeted to different subcellular compartments has led to the elucidation of several key aspects of sugar metabolism, including phloem loading mechanisms, the regulation of photosynthesis by sugars, the importance of sugar-metabolism compartmentation with regards to sucrose biosynthesis, storage and distribution, as well as the role of cell-wall invertase in phloem unloading and sink strength. (sun.ac.za)
Lipids2
Life functions through the specialized chemistry of carbon and water, and builds largely upon four key families of chemicals: lipids for cell membranes, carbohydrates such as sugars, amino acids for protein metabolism, and nucleic acid DNA and RNA for the mechanisms of heredity. (wikipedia.org)
Grape berries are extremely rich in K, which is involved in several physiological processes: enzyme activation, cellular membrane transport processes and translocation of assimilates, anion neutralisation, which is essential to the maintenance of membrane potential, and osmotic potential regulation, which controls the plant water relations, turgor maintenance and growth. (benthambooks.com)
Molecular6
The prevailing scientific hypothesis is that the transition from non-living to living entities on Earth was not a single event, but a process of increasing complexity involving the formation of a habitable planet, the prebiotic synthesis of organic molecules, molecular self-replication, self-assembly, autocatalysis, and the emergence of cell membranes. (wikipedia.org)
The evolutionary process could have involved molecular self-replication, self-assembly such as of cell membranes, and autocatalysis. (wikipedia.org)
The paradigm of water transport across the biological membrane has recently changed, when the molecular basis (aquaporins) was first identified by the team of Peter Agre. (benthambooks.com)
In: 'Molecular Aspects of Membrane Phenomena,' eds. (uni-mainz.de)
A molecular understanding of membrane traffic has broad implications for our understanding of growth control in cancer, receptor trafficking errors in heart disease, regulation of insulin secretion in diabetes and synaptic vesicle biogenesis and transport in neurological disorders. (stanford.edu)
Cell) books are molecular residing phrases and are useful from divide highlights under house. (cutechabeads.com)
Processes2
In this essay I would like to talk about the compartmentalisation of the cell and some important processes happen within the cell that requires the corporation of different organelles. (markedbyteachers.com)
Mammalian cells are one of the two types of eukaryotic cells, in which contains many internal membrane bounded structures called organelles, they are separated into different groups in order to increase their efficiency at bringing out particular function, and this is called compartmentalization, however there is processes that requires different organelles working together in order to take place, such as respiration (involves the cytoplasm and mitochondria) and Protein Synthesis (Nucleus, Ribosomes). (markedbyteachers.com)
Protein-Protein Inte1
9. Melchers, F., Köhler, G., Messer, W.: Stabilization of conformations of Escherichia coli beta-galactosidase by specific antibodies.In: 23rd Mossbach Colloquium of the Germany Society for Biological Chemistry on Protein-Protein Interactions, pp. 409-425, Springer, Berlin, 1972. (uni-mainz.de)
Cellular3
Cellular uptake of extracellular materials within membrane-limited vacuoles or microvesicles. (lookformedical.com)
Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. (lookformedical.com)
Cytoplasm2
Ribosomes exist within the cell as free ribosomes that free floats within the cytoplasm or fixed ribosomes that are attached to the rough endoplasmic reticulum. (markedbyteachers.com)
The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells. (lookformedical.com)
Eukaryotic3
Eukaryotic cells (from the Greek meaning truly nuclear) can be easily distinguished through a membrane-bound nucleus. (markedbyteachers.com)
Mammalian cells are different to Plant cells (which are also eukaryotic), they do not have a cellulose cell wall, and they are bounded by only plasma membrane, so they are sensitive to Osmotic lysis (the bursting or rupturing of the plasma membrane due to osmotic movement of water into the cell when the cell is in a hypotonic environment. (markedbyteachers.com)
20. Melchers, F.: Biochemical characterization of immunoglobulin-producing B-lymphocytes at different stages of their differentiation.In: 'Regulation of Growth and Differentiated Function in Eukaryotic Cells,' eds. (uni-mainz.de)
In: 'Regulation of the Immune System: Genes and the Cells in which They Function,' Vol. VI, eds. (uni-mainz.de)
The transcriptome response of A. caldus to elevated NaCl concentrations included changes in carbon flux, elevated glutathione synthesis, alterations in cell wall and membrane composition, the down-regulation in genes involved in flagellar synthesis and rotation, the reduced energy generation through sulfur oxidation, and the up-regulation in genes involved in DNA and protein repair. (bvsalud.org)
Genes1
Aging, the cruel fate from which no one can escape, is associated with drastic physiological changes amplified by the increased expression of genes related to cell damage. (thesciencebreaker.org)
Biology1
In: 'Perspectives in Membrane Biology,' eds. (uni-mainz.de)
20171
Program access grant to the STFC Harwell Laser Facility 'The Plant Cell Initiative: Protein interactions in the higher plant secretory pathway' 2017-2021 (approximate value of £200K). (brookes.ac.uk)
Pathway3
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. (lookformedical.com)
Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. (lookformedical.com)
A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation. (stanford.edu)
Proteins2
Golgi apparatus is the site where proteins produced by the ribosomes on rough endoplasmic reticulum further packaged and modified before releasing out of the cell through exocytosis. (markedbyteachers.com)
Ronan is a lecturer in the section Sustainable world of the School of Biological and Chemical Sciences at NUI Galway and has been working at the University of Galway since 2012. (universityofgalway.ie)
12. Melchers, F.: Possible roles of the carbohydrate groups in biological functions of the glycoproteins, immunoglobulin M and G. In: 'Int. Symp. (uni-mainz.de)
Transporters2
A membrane assay that indirectly measures the activity of efflux transporters. (atpasepathway.com)
Transgenic lines overproducing the yeast-derived invertase in either the vacuole (Vac-Inv) or apoplast (Apo-Inv) were utilised to analyse the effect of the altered sugar levels in sink and source organs on the expression of sugar transporters, as well as the endogenous cell wall invertase and inhibitors in these plants. (sun.ac.za)
Proliferation1
In: 'Control of Proliferation in Animal Cells', Cold Spring Harbor Laboratory, pp. 393-410, 1974. (uni-mainz.de)
Plant1
I am committed to interdisciplinary research, and an example of the successes gained from this approach is the project with Prof A Nabok (Engineering Sheffield Hallam University) using total internal reflection ellipsometry to quantify protein-membrane interactions on native plant membranes and human cell lines. (brookes.ac.uk)
Transport2
11. Melchers, F.: Synthesis, transport and secretion of immunoglobulin in lymphoid cells. (uni-mainz.de)
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components. (lookformedical.com)
Distinct2
the double membranes divide the mitochondrion into two distinct parts: the intermembrane space and the mitochondrial matrix. (markedbyteachers.com)
Moreover, we identify a distinct, N-terminal, higher affinity interaction interface between LRRK2 phosphorylated Rab8 and Rab10 termed 'Site #2', that can retain LRRK2 on membranes in cells to catalyze multiple, subsequent phosphorylation events. (stanford.edu)
Role1
Despite this abundance, Al is not considered an essential element and so far no experimental evidence has been put forward for a biological role. (frontiersin.org)
During stage I, starting at fruit set, berries grow through cell division.Stage II, called the Lag Phase, starts with a pause in berry growth while seed embryos start to form and grow. (campaignspace.se)
Cells propagated in vitro in special media conducive to their growth. (lookformedical.com)
Water1
The precursors to the development of a living cell like the LUCA are clear enough, if disputed in their details: a habitable world is formed with a supply of minerals and liquid water. (wikipedia.org)
Double1
the nuclear envelope is formed by a double membrane with nuclear pores. (markedbyteachers.com)
Plants1
Application of Si to plants promotes cell walls strength and provides additional support through increased mechanical and biochemical support. (researchsquare.com)
Production1
17. Melchers, F., Andersson, J.: Immunoglobulin production in B-lymphocytes: synthesis of the membrane-bound receptor and the secreted serum glycoprotein immunoglobulin M. Biochem. (uni-mainz.de)
Include2
Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. (lookformedical.com)
However, potential pathogens were also previously detected on seaweed thalli and include microorganisms capable of degrading cell wall polysaccharides ( 5 - 7 ). (asm.org)
Groups1
In the roots of Steen, White French, Jacquez and 1202 C the formation of multinucleate syncytia by the destruction of the walls of groups of cells often occurred. (sun.ac.za)
Life1
NASA defines life as "a self-sustaining chemical system capable of Darwinian [i.e., biological] evolution. (wikipedia.org)
Parts1
A partitioning within cells due to the selectively permeable membranes which enclose each of the separate parts, e.g., mitochondria, lysosomes, etc. (lookformedical.com)
Site1
it contains the DNA information (chromosomes) of the cell and is the site where DNA replication and RNA transcription take place, while the nucleolus is located in the centre of the nucleus containing ribosomes in various stages of synthesis, the nucleolus is also responsible for the manufacture of the ribosomes. (markedbyteachers.com)
Surface2
it is called 'Rough' because the attached ribosomes showed in electron microscopes a 'rough' surface on the membranes. (markedbyteachers.com)