In vivo development and in vitro characterization of a subclone of murine P388 leukemia resistant to bis(diphenylphosphine)ethane. (aspetjournals.org)
Индукция дифференцировки в клетках опухолевых линий in vivo и in vitro. (dissercat.com)
The compound has been found to show promising in vitro and in vivo activities against certain B-cell malignancies [ 12 ], and has been under preclinical toxicogical development in the National Cancer Institute Experimental Therapeutics (NExT) program. (biomedcentral.com)
The evidence for these anticancer effects, in vitro , in vivo , and clinical are summarised, and the putative mechanisms of their action outlined. (ecancer.org)
Toxoplasma gondii parasites were isolated in vitro and in vivo from a hare that had died of disseminated toxoplasmosis. (ox.ac.uk)
These findings suggest that host-parasite interaction plays a major role in determining the degree of pathogenicity, and that in vitro and in vivo isolation, if not followed by subsequent passages, may fail to reveal major differences in virulence between isolates. (ox.ac.uk)
Lymphocytic leukemia3
Additionally, nardosinone has demonstrated cytotoxic activity against cultured P-388 lymphocytic leukemia cells. (wikipedia.org)
Compound 4 exhibited cytotoxicity against P-388 (mouse lymphocytic leukemia) cell line with an ED 50 of 3.8 μg/mL. (mdpi.com)
T]he strong cytotoxic effect of Thujaplicin on murine P388 lymphocytic leukemia cell line [CLL, chronic lymphocytic leukemia] should be emphasized. (oil-testimonials.com)
Anti-Inflammatory Activity1
Tea tree oil has broad-spectrum antimicrobial and anti-inflammatory activity in vitro. (oil-testimonials.com)
Murine leukemia2
The compound 1 was further characterized with different techniques to gain more complete data and then tested for anticancer activity test against P-388 murine leukemia cells. (ijournalse.org)
Anticancer activity tests against P-388 murine leukemia cells revealed that compound 1 has an IC 50 of 2.35 µg/mL, confirming that the compound is categorized as an active anticancer agent and suggesting that the compound has promising potential that deserves further investigations. (ijournalse.org)
Antimicrobial1
In vitro studies [were] conducted by the author on antimicrobial and anthelmintic [destructive to parasitic worms] properties of some essential oils. (oil-testimonials.com)
Compound1
In in vitro studies, the compound has demonstrated concentration-dependent enhancement of bucladesine and staurosporine-induced neurite outgrowth. (wikipedia.org)
Cells2
In vitro cell viability, flow cytometry, fluorescence microscopy, qPCR and immunoblot was used to study the mechanism of action of silvestrol in MDA-MB-435 melanoma cells. (biomedcentral.com)
The results of our research indicate that Inotodiol isolated from Inonotus obliquus inhibited the proliferation of HeLa cells and induced apoptosis in vitro. (chemfaces.com)
Activity1
Study of the antioxidant and antidiabetic activity in vitro of free and encapsulated phenolic compounds of olive pomace. (ijournalse.org)
Study1
OBJECTIVE: To study the effects of early sequential enteral nutrition (ESEN) therapy and early non-sequential enteral nutrition (EN) therapy on the nutritional status, recovery, and quality of life of patients who undergo postoperative chemotherapy for esophageal cancer. (bvsalud.org)
Human1
Intracellular metabolism of 5,10-dideazatetrahydrofolic acid in human leukemia cell lines. (aspetjournals.org)
Murine6
6. In vitro multidrug resistance of P388 murine leukemia selected for resistance to diaziquone. (nih.gov)
8. Resistance to purine and pyrimidine nucleoside and nucleobase analogs by the human MDR1 transfected murine leukemia cell line L1210/VMDRC.06. (nih.gov)
11. Multidrug resistance of murine leukemia cells characterization and correlation with cytochrome P-450 dependent activities, cytosolic calcium and cell cycle state. (nih.gov)
19. In vivo development and in vitro characterization of a subclone of murine P388 leukemia resistant to bis(diphenylphosphine)ethane. (nih.gov)
Purification Of Active Compounds From Kecapi Leaves That Have Potential As Anticancer Fon IN Vitro On Murine Cells Leukemia A P-388. (uisu.ac.id)
The cell inhibition activities of several Annonaceous acetogenins, covering the three major structural classes of bis-adjacent, bis-non-adjacent, and single tetrahydrofuran (THF) ring compounds and their respective ketolactone rearrangement products, were tested in an in vitro disk diffusion assay against three murine (P388, PO3, and M17/Adr) and two human (H8 and H125) cancerous cell lines as well as a non-cancerous immortalized rat GI epithelial cell line (I18). (cancer.org)
Cytotoxicity3
In vitro studies of human melanocytes exposed to arbutin at concentrations below 300 µg/mL reported decreased tyrosinase activity and melanin content with little evidence of cytotoxicity. (nih.gov)
Moreover, the in vitro cytotoxicity, anti-inflammatory, and antibacterial activity of 1-17 and 1a were evaluated. (bvsalud.org)
We studied the effects of cyclosporin A and PSC-833 on in vitro drug retention and cytotoxicity in resistant cell lines overexpressing Pgp, MRP-1, and BCRP and on nuclear-cytoplasmic drug distribution and cytotoxicity in cells overexpressing LRP. (aacrjournals.org)
Antitumor3
18. Antitumor activity of idarubicin, a derivative of daunorubicin, against drug sensitive and resistant P388 leukemia. (nih.gov)
Shows significant antitumor properties in vitro (IC 50 = 480 nM against mouse B16 melanoma cells and IC 50 = 500 nM against P388 leukemia cells). (adipogen.com)
When the compounds were injected i.p., alpha- and gamma-tocotrienols were effective against sarcoma 180, Ehrlich carcinoma, and IMC carcinoma, and gamma-tocotrienol showed a slight life-prolonging effect in mice with Meth A fibrosarcoma, but thetocotrienols had no antitumor activity against P388 leukemia at doses of 5-40 mg/kg/d. (tocotrienolresearch.org)
Inhibition2
Tocotrienols showed growth inhibition of human and mouse tumor cells when the cells were exposed to these agents for 72 h in vitro, whereas tocopherol did not show any marked cytotoxic activity. (tocotrienolresearch.org)
Tumor cell growth inhibition by several Annonaceous acetogenins in an in vitro disk diffusion assay. (cancer.org)
Characterization3
2. Characterization of four drug-resistant P388 sublines: resistance/sensitivity in vivo, resistance-and proliferation-markers, immunogenicity. (nih.gov)
15. Cytogenetic and molecular characterization of tumors in nude mice derived from a multidrug-resistant human leukemia cell line. (nih.gov)
Our results indicate that NBPQD is able to alleviate leukemia and it is worthy of further characterization as a potential anti-leukemic drug. (japsonline.com)
Doxorubicin1
14. Non-P-glycoprotein mediated mechanism for multidrug resistance precedes P-glycoprotein expression during in vitro selection for doxorubicin resistance in a human lung cancer cell line. (nih.gov)
Multidrug resistance1
Overexpression of the multidrug resistance proteins P-glycoprotein (Pgp), multidrug resistance protein (MRP-1), breast cancer resistance protein (BCRP), and lung resistance protein (LRP) is associated with treatment failure in acute myeloid leukemia (AML) and other malignancies. (aacrjournals.org)
Inhibit1
[10] Unidentified endophytic fungi associated with C. mollisimum produces 5-hidroxyamulocyn that inhibit the growth of Aspergillus niger and P388 cells (leukemia) with IC 50 1.56 ug / ml and 2.10 ug / ml respectively. (genderi.org)
Cytotoxic activity1
Additionally, nardosinone has demonstrated cytotoxic activity against cultured P-388 lymphocytic leukemia cells. (wikipedia.org)
Resistant1
3. Multifactorial resistance to adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of adriamycin-sensitive and -resistant P388 leukemia. (nih.gov)
Drug1
Because the efflux transporter P-glycoprotein (P-gp) is involved in the absorption, distribution, and excretion of many drugs and often participates in drug-drug interactions, we studied the effect of a crude kava extract and the main kavalactones kavain, dihydrokavain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin on the P-gp-mediated efflux of calcein-acetoxymethylester in the P-gp-overexpressing cell line P388/dx and the corresponding cell line P388. (nih.gov)
Expression1
The results strongly suggest that the regression phenomenon is an in vitro expression of long-term T-cell-mediated immunity to EB virus which the large majority, if not all, infected individuals possess. (nih.gov)
Development1
Obesity, smoking, and exposure to electromagnetic fields and ionizing radiation have been reported to be risk factors for the development of leukemia. (japsonline.com)
Diverse1
Causes of leukemia are diverse and they could be familial, infectious, physical, or chemical depending on the cell type and the individual variations from one patient to another ( Pui, 1995 ). (japsonline.com)