Vitro anti bacterial agents. Medical search. Frequent questions

It can also facilitate the conjugative transfer of multidrug resistance (MDR) plasmids between commensal and pathogenic bacteria which is a significant public and animal health concern as it may affect our ability to treat bacterial infections. (nih.gov)
IMPORTANCE The spread of antimicrobial resistance presents a grave threat to public health and animal health and is affecting our ability to respond to bacterial infections. (nih.gov)
Garlic ( Allium sativum ), a popular food spice and flavoring agent, has also been used traditionally to treat various ailments especially bacterial infections for centuries in various cultures around the world. (frontiersin.org)
In alternative medicine, the roots have been used to cleanse the blood and liver, reduce inflammation and control bacterial infections. (yeastinfectionadvisor.com)
Subjects with wound infections could have received aztreonam and/or metronidazole as adjunctive therapy for gram-negative bacterial coverage, if needed. (centerwatch.com)
Biofilm-mediated Antibiotic-resistant Oral Bacterial Infections: Mechanism and Combat Strategies. (ac.ir)
President & CEO: Isao Teshirogi, Ph.D.) (hereafter "Shionogi") today announces the back to back publication of two studies in The Lancet Infectious Diseases journal highlighting the efficacy and safety of cefiderocol against some of the most difficult-to-treat Gram-negative bacterial infections, including nosocomial pneumonia (NP), bloodstream infections (BSI), sepsis, and complicated urinary tract infections (cUTI). (dutchnews.nl)
Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. (mdpi.com)
A Novel Fosfomycin-Trimethoprim-Sulfamethoxazole Combination Exhibits Marked In Vitro Antibacterial Synergy Against Bacteria Causative of Urinary Tract Infections. (asm.org)
Repurposing of Drugs to Fight Persistent Infections-Antibacterial Compounds Against Non-growing Bacteria. (asm.org)
Levofloxacin is a fluoroquinolone antibacterial indicated in adults (18 years of age and older) with infections caused by designated, susceptible bacteria and in pediatric patients where indicated (1, 12.4). (nih.gov)
To reduce the development of drug-resistant bacteria and maintain the effectiveness of levofloxacin and other antibacterial drugs, levofloxacin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria (1.15). (nih.gov)
2) The direct bactericidal activity of HAMLET, a human milk protein-lipid complex, against various bacterial species as well as its adjuvant activity in sensitizing bacteria to a broad range of common antibiotics to provide novel therapeutic strategies against respiratory and other infections with antibiotic-resistant bacteria. (lu.se)
Des infections microbiennes ont été observées chez 30% (155/519) de l'ensemble des malades admis au service de soins intensifs pour adultes de l'Hôpital universitaire de Jordanie à Amman en 1993. (who.int)
Antibacterial drugs have no benefit in treating viral infections and can cause harm. (cdc.gov)
An important concept in the evaluation of data regarding transfusion-transmitted bacterial infections (TTBIs) is the definition of a case. (medscape.com)

Water, acetone-water and ethanol-water based extracts were tested against selected gram-positive (Staphylococcus aureus) and gram-negative (Aeromonas hydrophila, Pseudomonas fluorescens) fish bacterial pathogens. (ijcmas.com)
The present investigation established 1,5-bis(2-hydroxyphenyl)pent-1,4-diene-3-one (lc)asalead compound with potential against a panel of pathogenic bacterial strains, Staphylococcus (coagulase negative), Escherichia coli, Pseudomonas aeruginosa, Acenetobacter sp. (scielo.org.za)
In 2006, research Gentil and associates from the University of Ribeirão Preto in Brazil, implanted 27 teeth with a bacterial mix of Pseudomonas aeruginosa, Escherichia coli, Lactobacillus acidophilus , Streptococcus mutans and Candida albicans . (yeastinfectionadvisor.com)
Antimicrobial activity was screened in vitro against Pseudomonas sp. (ijpsonline.com)

The organosulfur compounds of garlic exhibit a range of antibacterial properties such as bactericidal, antibiofilm, antitoxin, and anti-quorum sensing activity against a wide range of bacteria including multi-drug resistant (MDR) strains. (frontiersin.org)
This recommendation was retired and replaced with a statement mentioning in vitro resistance of casirivimab/imdevimab to circulating strains of COVID-19 in the US. (idsociety.org)
Mupirocin has been shown to be active against most strains of Staphylococcus aureus and Streptococcus pyogenes, both in vitro and in clinical studies. (nih.gov)
A mixture of equal proportions of petroleum ether extract from avocado kernels and methanolic extract from mango kernels was effective on the majority of 36 bacterial strains and presented excellent results against S. aureus. (univ-lille.fr)

Mupirocin inhibits bacterial protein synthesis by reversibly and specifically binding to bacterial isoleucyl transfer-RNA synthetase. (nih.gov)

In-vitro Antibacterial Activity of a Fosfomycin-Trimethoprim-Sulfamethoxazole Combination Against a Bacterial Collection of Multidrug-Resistant Clinical Isolates. (asm.org)
Antibacterial susceptibility testing was first performed for all isolates by a disk diffusion method on Mueller-Hinton agar [10]. (who.int)
Multiple bacterial isolates from a single patient with the same resistance patterns were considered as one isolate for studying minimum inhibitory concentration (MIC) using Micro Scan, Type TN dried panel (Baxter Health Care Corporation, West Sacramento, California, USA). (who.int)
These recommendations include the need for a) in vitro drug susceptibility testing of Mycobacterium tuberculosis isolates from all patients and reporting of these results to the health department, b) initial four-drug regimens for the treatment of TB, and c) initial directly observed therapy for persons with TB. (cdc.gov)
From Dusk to Dawn: Understanding the Impact of Ertapenem Resistance Mechanisms on the In Vitro Potency of Other Drugs Among Enterobacter cloacae Complex Isolates. (medscape.com)

We report here for the first time the in vitro assembly of peptidoglycan using recombinant penicillin-binding proteins from pneumococcus and the precursor lipid II. (nih.gov)
Penicillins inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins. (medscape.com)

Our chemostat system provides a good representation of bacterial interactions, including antibiotic resistance transfer in vivo It can be used as an ethical and relatively inexpensive approach to model dissemination of antibiotic resistance within the gut of any animal or human and refine interventions that mitigate its spread before employing in vivo studies. (nih.gov)

Here we use the chicken gut microbiota as an exemplar to model the effects of bacterial infection, antibiotic administration, and plasmid transfer. (nih.gov)
This study reports the in vitro efficacy of a mixture of plant extracts used as antibacterial agents loaded in a dressing to prevent infection in a wound. (univ-lille.fr)
Our laboratory is focused on understanding host-pathogen interactions, with emphasis on respiratory pathogens, and to use this knowledge to develop novel preventive and therapeutic strategies to protect against bacterial infection, especially in this era of increasing antibiotic resistance. (lu.se)
1) Biofilm formation during bacterial colonization and how the composition of the respiratory microbiota as well as environmental factors (host inflammation, virus infection) modulate or trigger transition from colonization to infection, such as otitis media, pneumonia and sepsis. (lu.se)

The in vitro spectrum of activity of daptomycin encompasses most clinically relevant Gram-positive pathogenic bacteria. (globalrph.com)
The antibacterial activity against various pathogenic and drug-resistant bacteria was tested using crude garlic extracts, garlic powder (GP), garlic extracts using various solvents, GO, and phytochemicals isolated from garlic. (frontiersin.org)
The in vitro effect of manuka honeys on growth and adherence of oral bacteria. (microbiologyresearch.org)
A myriad of agents can potentially be transmitted through blood transfusions, including bacteria, viruses, and parasites. (medscape.com)
Bacteria or, for that matter, any infective agent that potentially evades the sterility of the transfusion loop can come from the donor's blood or skin or from a contaminated environment. (medscape.com)

Our work demonstrates that the in vitro gut model provides a powerful screening tool that can be used to assess and refine interventions that mitigate the spread of antibiotic resistance in the gut before undertaking animal studies. (nih.gov)
Understanding the molecular basis of bacterial cell wall assembly is of paramount importance in addressing the threat of increasing antibiotic resistance worldwide. (nih.gov)

Antibacterial efficacy of manuka honey, ocimum sanctum, curcuma longa and 0.2% chlorhexidine mouthwash on the level of streptococcus mutans. (greenmedinfo.com)

Antibacterial agents may decrease efficacy if coadministered. (medscape.com)
Oral Pharmacokinetics and Efficacy of BWC0977, a Novel Bacterial Topoisomerase Inhibitor. (asm.org)
A Randomized, Double-Blind, Placebo Controlled Multicenter Study to Evaluate the Efficacy and Safety of CAL02 Administered Intravenously in Addition to Standard of Care in Subjects With Severe Community Acquired Bacterial Pneumonia (SCABP). (asm.org)
e Bebtelovimab is active in vitro against all circulating Omicron subvariants, but there are no clinical efficacy data from placebo-controlled trials that evaluated the use of bebtelovimab in patients who are at high risk of progressing to severe COVID-19. (cdc.gov)

Aim: The present article aims to study and compare the antioxidant activity of aqueous solutions of leaves and flowers of Sambucus nigra L obtained at different exposure times and assess the antibacterial activity of these solutions against Escherichia coli ATCC 8739, Salmonella NCTC 6017, Listeria monocytogenes NCTC 11994, and Staphylococcus aureus ATCC 25093. (researchgate.net)

therefore, cross-resistance between tedizolid and other classes of antibacterial drugs is unlikely. (centerwatch.com)
Due to this unique mode of action, mupirocin demonstrates no in vitro cross-resistance with other classes of antimicrobial agents. (nih.gov)
The unusual antibacterial activity of medical-grade Leptospermum honey: antibacterial spectrum, resistance and transcriptome analysis. (microbiologyresearch.org)
Exploring the Effect of Sub-MIC Antibiotic Exposure on Bacterial Hetero-resistance at Single Cell Level. (asm.org)
Bacterial resistance to antibiotics: active efflux and reduced uptake. (ijmedrev.com)

The antibacterial activity of tedizolid is mediated by binding to the 50S subunit of the bacterial ribosome resulting in inhibition of protein synthesis. (centerwatch.com)

Daptomycin exhibits rapid, concentration-dependent bactericidal activity against Gram-positive organisms in vitro. (globalrph.com)
Daptomycin maintained bactericidal activity in vitro against stationary phase S. aureus in simulated endocardial vegetations. (globalrph.com)

Until now, the crucial transpeptidase activity that is inhibited by β-lactams was not amenable to in vitro investigation with enzymes from Gram-positive organisms, including streptococci, staphylococci, or enterococci pathogens. (nih.gov)
The mode of antibacterial action of 1c was also studied by scanning electron microscopy, which showed membrane disruption and cell lysis of the organisms during the exposure of the tested compound. (scielo.org.za)
As with other antibacterial products, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. (nih.gov)

We used an in vitro chemostat system to approximate the chicken cecal microbiota, simulate colonization by an MDR Salmonella pathogen, and examine the dynamics of transfer of its MDR plasmid harboring several genes, including the extended-spectrum beta-lactamase bla CTX-M1 We also evaluated the impact of cefotaxime administration on plasmid transfer and microbial diversity. (nih.gov)
Microbiota oral contains bacterial spores. (medscape.com)

The final dressing containing the mixture of avocado and mango extracts presented excellent antibacterial activity against S. aureus. (univ-lille.fr)
Microbiological tests demonstrated that a wound dressing loaded with avocado/mango seed extract induced additional bacterial reduction of 3 Log10 and 2 Log10 against S. aureus and P. aeruginosa respectively but no additional bacterial reduction of C. albicans compared to the control. (univ-lille.fr)

Bacterial community profiles obtained by culture-independent methods showed that Salmonella inoculation resulted in no significant changes to bacterial community alpha diversity and beta diversity, whereas administration of cefotaxime caused significant alterations to both measures of diversity, which largely recovered. (nih.gov)

The principal phytochemicals that exhibit antibacterial activity are oil-soluble organosulfur compounds that include allicin, ajoenes, and allyl sulfides. (frontiersin.org)
Health benefits that are associated with the use of garlic are attributed to its anticancer, anti-inflammatory, antifungal, antiviral, and antibacterial activity. (frontiersin.org)
However, there is a limited production of new antibiotic lines, so using new materials like nanoparticles (NPs) which have high antibacterial activity, is a promising solution to this problem. (springeropen.com)
This recommendation was retired and replaced with a statement mentioning that the US FDA withdrew Emergency Use Authorization for bebtelovimab , the one anti-SARS CoV-2 neutralizing antibody product that had retained in vitro activity against most previously circulating SARS-CoV-2 variants, leaving no available neutralizing antibody product in the United Sates for treatment of COVID-19. (idsociety.org)
In vitro antibacterial and non-stick activity of extracts from leaves of Psidium guineense Sw. (bvsalud.org)
The principal metabolite, monic acid, is eliminated by renal excretion, and demonstrates no antibacterial activity. (nih.gov)
The diameters (in millimeters) of the growth inhibition zones of four pathogens were measured, and a comparative assessment of their antibacterial activity was made. (researchgate.net)
Exploring Potential MCR-1 Inhibitors: Restoring In Vitro Polymyxin Activity in MCR-1-Producing Enterobacteriales. (asm.org)
Indoles exhibited better antibacterial activity compared to benzimidazoles. (ijpsonline.com)

LPO is a highly effective antimicrobial agent. (phcoker.com)
The water samples were di- of inhibition of each antimicrobial agent bacterium survives in water systems as rectly placed in ice, for transportation was measured and recorded as resistant, a parasite of protozoa [4], which are and examination within the same day. (who.int)
Penicillin is the antimicrobial agent of choice for treatment of group A streptococcal pharyngitis. (medscape.com)

Bacterial factors that contribute toward colonization of respiratory tract or prosthetic devices such as intravascular, surgical catheters and endotracheal tubes include cationic surface charge, flagella and fimbriae, which assist adhesion, and biofilm formation. (medscape.com)

Stavri M, Piddock LJ, Gibbons S. Bacterial efflux pump inhibitors from natural sources. (ijmedrev.com)

Probing the breadth of macrolide glycosyltransferases: in vitro remodeling of a polyketide antibiotic creates active bacterial uptake and enhances potency. (ox.ac.uk)

Manuka honey appears to be an effective antibacterial wound healing agent against MRSA-colonized leg ulcers. (greenmedinfo.com)
In this study, the effect of manuka honey on S. pyogenes (M28) was investigated in vitro with planktonic and biofilm cultures using MIC, MBC, microscopy and aggregation efficiency. (microbiologyresearch.org)

further studies are needed to confirm these extracts to be natural antibacterial agents for use in controlling dental caries. (bvsalud.org)
The findings of the recent study suggest the use of EOs as natural antibacterial agents for food preservation. (scielo.br)

These agents are indicated for topical application to hold closed easily approximated skin edges of wounds. (medscape.com)

The reactive organosulfur compounds form disulfide bonds with free sulfhydryl groups of enzymes and compromise the integrity of the bacterial membrane. (frontiersin.org)

Considering the properties of licorice in traditional medicine, this study aimed to investigate the antibacterial properties of licorice root extract with different concentrations compared with Chlorhexidine mouthwash and Doxycycline antibiotic on Fusobacterium nucleatum in vitro. (ac.ir)
The antibacterial effect of Chlorhexidine mouthwash 0.2% and Doxycycline 100 mg antibiotic were also determined to be compared with licorice extract. (ac.ir)

A systematic and comparative study has been made starting from a naturally-occurring chalcone nucleus to design effective antibacterial agents. (scielo.org.za)

This report updates the 2004 recommendations by the Advisory Committee on Immunization Practices (ACIP) regarding the use of influenza vaccine and antiviral agents (CDC. (cdc.gov)

A meta-analysis of 22 studies of bacterial contamination rate estimates for apheresis (AP), platelet-rich plasma (PRP), and buffy coat (BC) collection methods found an overall mean contamination rate of 0.51 per 1000 components (95% confidence index [CI], 0.38-0.67). (medscape.com)

β-Glycyrrhetinic acid inhibits the bacterial growth and biofilm formation by supragingival plaque commensals. (ac.ir)

To date, 11 different efflux pumps of the RND family in P. aeruginosa that enable the efflux of antibiotics/anti-microbial production have been detected. (ijmedrev.com)

Tickborne rickettsial diseases continue to cause severe illness and death in otherwise healthy adults and children, despite the availability of low-cost, effective antibacterial therapy. (cdc.gov)
Recognizing viral and bacterial diseases for which specific therapy is available is important. (medscape.com)
In 2009, the American Association of Blood Banks (AABB) published a detailed description of 68 infectious agents capable of being transmitted by blood transfusion and prioritizing emerging infectious diseases for which there was not yet an implemented intervention. (medscape.com)

Clostridium difficile is well recognized as the etiologic agent of pseudomembranous colitis and has been implicated as the cause of 10%-25% of cases of antimicrobial drug-associated diarrhea ( 1 ). (cdc.gov)
Treatment with anti-infectives alters normal colon flora and may permit overgrowth of Clostridium difficile . (drugs.com)

Tanabe S, Desjardins J, Bergeron C, Gafner S, Villinski JR, Grenier D. Reduction of bacterial volatile sulfur compound production by licoricidin and licorisoflavan A from licorice. (ac.ir)
The LPO enzyme functions as a natural compound of the non-immune biological defense system of mammals and it catalyzes the oxidation of the thiocyanate ion into the antibacterial hypothiocyanate. (phcoker.com)

Our study demonstrated the scope for interest in plant species extracts provided by agricultural co-products in developing a new antibacterial wound dressing. (univ-lille.fr)

Assessing the Ability of Hospital Diagnosis Codes to Detect Inpatient Exposure to Antibacterial Agents. (medscape.com)

Avoid coadministration of cholera vaccine with systemic antibiotics since these agents may be active against the vaccine strain. (medscape.com)

also known as antibiotic-associated diarrhea and colitis or pseudomembranous colitis) reported with nearly all anti-infectives, including fosfomycin, and may range in severity from mild diarrhea to fatal colitis. (drugs.com)

The aim of this study was to determine the antioxidant and antibacterial property of Nelumbo nucifers (lotus) leaf extract. (ijcmas.com)
Materials and Methods: After the preparation of 0.5 McFarland bacterial suspension, the plant and its ethanolic extract, and six extract dilutions were also prepared. (ac.ir)

Organisms7

Diseases1

Chemicals and Drugs1

Phenomena and Processes1

Infections16

Pseudomonas4

Strains4

Inhibits bacterial protein synthesis1

Isolates5

Penicillin-Binding2

Vivo1

Infection4

Bacteria5

Antibiotic resistance2

Streptococcus1

Efficacy4

Escherichia1

Resistance5

Synthesis1

Bactericidal2

Organisms3

Microbiota2

Aureus2

Cefotaxime1

Activity9

Antimicrobial agent3

Colonization1

Inhibitors1

Potency1

Manuka2

Natural antibacterial agents2

Topical Application1

Enzymes1

Mouthwash2

Effective antibacterial agents1

Antiviral Agents1

Meta Analysis1

Formation1

Aeruginosa1

Diseases3

Clostridium2

Compound2

Species1

Exposure1

Systemic1

Pseudomembranous colitis1

Extract2