Viruses glycoproteins. Medical search. Frequent questions

Using Schmallenberg virus, a recently emerged OBV, we also show that the projecting spike is the major target of the neutralizing antibody response, and provide X-ray structures in complex with two protecting antibodies. (rcsb.org)
Development of a fluorescent antibody virus neutralisation test (FAVN test) for the quantitation of rabies-neutralising antibody. (microbiologyresearch.org)
Collaboration of antibody and inflammation in clearance of rabies virus from the central nervous system. (microbiologyresearch.org)
Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses. (pasteur.fr)
Human IgG antibody Laboratories manufactures the virus glycoprotein spikes reagents distributed by Genprice. (mytaq.com)
After immunization, there was a robust induction of glycoprotein-specific antibody responses and the establishment of cytokine-producing, antigen-specific memory T-cell responses. (infectiousdiseaseadvisor.com)
Among these, the glycoprotein is the most important as it is the major contributor to pathogenicity and virus neutralizing antibody response. (ijsr.net)
Mouse anti Respiratory syncitial virus, major surface glycoprotein G antibody, clone 8C5 recognizes the major glycoprotein G of Respiratory Syncytial virus (RSV). (bio-rad-antibodies.com)

Once the virus gets to the surface of the lipid droplets it recruits the virus no-structural proteins and replication complex. (wikipedia.org)
Several cell membrane proteins have been identified as herpes simplex virus (HSV) entry mediators (Hve). (nih.gov)
This study was undertaken to identify antigenic epitopes on two of the surface glycoproteins of BRSV, the fusion (F) and attachment (G) proteins, the major surface viral antigens, for inclusion into a novel subunit peptide vaccine. (alliedacademies.org)
Expression of the G genes using recombinant vaccinia virus expressing the T7 RNA polymerase showed that the G proteins of both strains of PVM were expressed on the surface of cells transfected in vitro. (warwick.ac.uk)
The genome of rabies virus encodes five proteins, the nucleoprotein, the phosphoprotein, the matrix protein, the glycoprotein, and the RNA-dependent RNA polymerase. (ijsr.net)
The efficiency of viruses in cancer therapy is enhanced by proteins that mediate the fusion of infected cells with their neighbors. (elsevierpure.com)
The RNA contains information to specify the amino acids that make up the proteins, which are the actual building blocks for the virus particle. (medlineplus.gov)
The production of the antiphospholipid antibodies may coincide with exposure to foreign invaders, such as viruses and bacteria, that are similar to normal human proteins. (medlineplus.gov)

BN-Filo Ebola vaccine regimen (ClinicalTrials.gov, no. bola virus (EBOV) antibodies have been found NCT02509494) ( 2 , 3 ). (cdc.gov)
Flow chart of participants screened for the Ebola virus vaccine trial and seroprevalence study in a community affected by the 2014-2016 Ebola outbreak, Sierra Leone. (cdc.gov)
The filoviruses, Marburg virus and Ebola virus, cause severe hemorrhagic fever with high mortality in humans and nonhuman primates. (nih.gov)
Although there have been significant breakthroughs in the Ebola virus disease vaccine development field, there remains an important need for prophylactic anti-Ebola virus vaccine candidates that elicit long-lasting immune responses. (infectiousdiseaseadvisor.com)
Therefore, this study designed a novel synthetic anti-Ebola virus glycoprotein DNA vaccine as a strategy to expand protective breadth against diverse Ebola virus strains and evaluated the impact of vaccine dosing and route of administration on protection against lethal Ebola virus-Makona challenge in nonhuman primates. (infectiousdiseaseadvisor.com)
The anti-Ebola virus glycoprotein DNA vaccination was delivered in a multiple-injection regimen by intramuscular administration and in a 2-injection regimen by intradermal administration, followed by electroporation. (infectiousdiseaseadvisor.com)
Nonhuman primates were challenged on day 20 postimmunization with 1000 50% tissue culture infective dose of Ebola virus/H.sapiens-tc/GIN/2014/Makona-C07. (infectiousdiseaseadvisor.com)
Results showed that multiple-injection regimens of the anti-Ebola virus glycoprotein DNA vaccine delivered by intramuscular administration followed by electroporation were 100% protective against the lethal Ebola virus-Makona challenge. (infectiousdiseaseadvisor.com)
Of note, when the anti-Ebola virus glycoprotein DNA vaccine was by 2 injections delivered intradermally followed by electroporation, a strong immunogenicity was generated and was also 100% protective against the lethal Ebola virus-Makona challenge. (infectiousdiseaseadvisor.com)
Further, although reports of long-term immunogenicity following DNA or other experimental vaccine administration are lacking, results showed that the anti-Ebola virus glycoprotein DNA vaccine induced long-term immune responses in the nonhuman primates. (infectiousdiseaseadvisor.com)
Ebola virus glycoprotein stimulates IL-18-dependent natural killer cell responses. (ox.ac.uk)
In human Ebola virus infection, clinical outcome is strongly associated with the initial innate cytokine response, but the role of NK cells has not been thoroughly examined.METHODSThe novel 2-dose heterologous Adenovirus type 26.ZEBOV (Ad26.ZEBOV) and modified vaccinia Ankara-BN-Filo (MVA-BN-Filo) vaccine regimen is safe and provides specific immunity against Ebola glycoprotein, and is currently in phase 2 and 3 studies. (ox.ac.uk)
Here, we analyzed NK cell phenotype and function in response to Ad26.ZEBOV, MVA-BN-Filo vaccination regimen and in response to in vitro Ebola glycoprotein stimulation of PBMCs isolated before and after vaccination.RESULTSWe show enhanced NK cell proliferation and activation after vaccination compared with baseline. (ox.ac.uk)
Ebola glycoprotein-induced activation of NK cells was dependent on accessory cells and TLR-4-dependent innate cytokine secretion (predominantly from CD14+ monocytes) and enriched within less differentiated NK cell subsets. (ox.ac.uk)
We demonstrate that NiV-G is largely devoid of the oligomannose-type glycans that in viruses such as human immunodeficiency virus type 1 and Ebola virus influence viral tropism and the host immune response. (ox.ac.uk)

Among the most promising filovirus vaccines under development is a system based on recombinant vesicular stomatitis virus (rVSV) that expresses an individual filovirus glycoprotein (GP) in place of the VSV glycoprotein (G). The main concern with all replication-competent vaccines, including the rVSV filovirus GP vectors, is their safety. (nih.gov)
Glycoprotein fragment associated with vesicular stomatitis virus after proteolytic digestion. (wikidata.org)

The nine E-glycoprotein-reactive monoclonal antibodies also neutralized dengue 2 virus in a plaque reduction assay. (ajtmh.org)
The protective monoclonal antibodies were directed against viral determinants that fell into at least three spatially separate families of epitopes on E-glycoprotein, the antigenicities of which were preserved after heat/detergent denaturation. (ajtmh.org)
Development of a qualitative indirect ELISA for the measurement of rabies virus-specific antibodies from vaccinated dogs and cats. (microbiologyresearch.org)
We describe here the isolation of human neutralizing antibodies (nAbs) against tetrameric Gn/Gc glycoprotein spikes from PUUV-experienced donors. (pasteur.fr)
Two monoclonal antibodies raised against Sindbis virus were shown to be specific for the envelope glycoprotein E1 by radioimmunoprecipitation (RIP). (microbiologyresearch.org)
Both monoclonal antibodies could enhance virus infectivity of Fc receptor-bearing macrophage-like cells when present at suitable dilutions. (microbiologyresearch.org)
These functions are enhanced during secondary immune responses and after vaccination by synergy with effector T cells and virus-specific antibodies. (ox.ac.uk)
Naturally Acquired Rift Valley Fever Virus Neutralizing Antibodies Predominantly Target the Gn Glycoprotein. (ox.ac.uk)
Numerous animal studies have demonstrated that protective immunity is acquired following RVF virus (RVFV) infection and that this correlates with acquisition of virus-neutralizing antibodies (nAbs) that target the viral envelope glycoproteins. (ox.ac.uk)
We further demonstrate the existence in serum of protective neutralizing antibodies targeting co-dominant fusion (F) glycoprotein epitopes. (elsevierpure.com)
These data suggest a cooperative mechanism for MARV neutralization by antibodies that target different GP Palmitic acid epitopes and an important role of non-neutralizing mAbs in virus clearance during infection. (nuche.org)
Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits. (bvsalud.org)
Here we have cloned 113 human monoclonal antibodies (mAbs) specific for LASV glycoproteins from memory B cells of Lassa fever survivors from West Africa . (bvsalud.org)
Although each is a distinct virus, they share some antigenic components, such that antibodies that react to one type may "neutralize" the other. (medscape.com)
The onset of clinical symptoms is correlated with the development of specific antibodies to the virus. (medscape.com)
The antibodies that cause antiphospholipid syndrome are called lupus anticoagulant, anticardiolipin, and anti-B2 glycoprotein I. These antibodies are referred to as antiphospholipid antibodies. (medlineplus.gov)
Laboratory testing with a rapid conducted at that time showed that 6.1% of the residents assay suggested that a dengue virus (DENV) was the caus- in nearby regions of Uganda had specifi c antibodies to ative agent. (folkhalsomyndigheten.se)
The solution has identified and patented B cell epitopes of filovirus glycoprotein and has validated the ability of synthetic epitopes and their antibodies to capture host specific IgG responses in survivor serum and recombinant GP, respectively. (who.int)

Antigenic characterisation of two Sindbis envelope glycoproteins separated by isoelectric focusing. (microbiologyresearch.org)
Its genome consists of single stranded, negative sense RNA that encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein. (bio-rad-antibodies.com)
Here, we characterized the immune response to the viral envelope glycoproteins, Gn and Gc, in RVFV-exposed Kenyan adults. (ox.ac.uk)

Identification of amino acids controlling the low-pH-induced conformational change of rabies virus glycoprotein. (microbiologyresearch.org)

The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes. (antikoerper-online.de)
The epitopes of the Lassa virus (LASV) surface glycoproteins recognized by naturally infected human hosts have not been identified or characterized. (bvsalud.org)
The Pan-Filovirus Rapid Diagnostic Test is premised on the identity of conserved epitopes of filovirus glycoprotein (GP) with potential for intra-genera differentiation. (who.int)

and spike glycoprotein or spike protein (red, tall spike). (medlineplus.gov)
The spike glycoprotein helps the virus latch onto and gain entry into the host cell, so that the virus can infect the cell. (medlineplus.gov)

Similar to influenza C virus (ICV), IDV also has seven segments in its genome and has only one major surface glycoprotein, called the hemagglutinin-esterase-fusion (HEF) protein, for receptor-binding, receptor-destroying, and membrane fusion. (flu.org.cn)

The molecular characterisation of the major glycoproteins of pneumonia virus of mice (PVM) was undertaken to identify the molecular basis for different pathogenicities for two strains of PVM. (warwick.ac.uk)
The lipid envelope contains 2 major glycoproteins. (medscape.com)

Here we report X-ray crystallography studies of four different OBVs showing that the spikes are formed by an N-terminal extension of the fusion glycoprotein Gc. (rcsb.org)
The Virus Glycoprotein Spikes reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (mytaq.com)
Coronaviruses are RNA viruses with glycoprotein spikes that give them a crown like appearance [1,2]. (bvsalud.org)

Interaction between gp120 and ITGA4/ITGB7 would allow the virus to enter GALT early in the infection, infecting and killing most of GALT's resting CD4+ T-cells. (antikoerper-online.de)
Virus transmission to permissive T-cells occurs either in trans (without DCs infection, through viral capture and transmission), or in cis (following DCs productive infection, through the usual CD4-gp120 interaction), thereby inducing a robust infection. (antikoerper-online.de)
Enhancement of dengue virus infection in monocytes by flavivirus antisera. (microbiologyresearch.org)
During infection both glycoproteins are found in the Golgi complex and co-expression is considered as a prerequisite for localization to the Golgi complex (2). (mytaq.com)
Objective: The recent availability of novel antiviral drugs has raised new hope for a more effective treatment of hepatitis C virus (HCV) infection and its severe sequelae. (uninsubria.it)
In view of reported high frequency of laboratory aerosol infection that occurred in workers manipulating high concentrations of Pichinde virus, it is strongly recommended that work with high concentrations of Level 2 arenaviruses be done at Level 3. (cdc.gov)
In 2017, rapid human immunodeficiency virus (HIV) testing services enabled the HIV diagnosis and treatment of approximately 15.3 million persons with HIV infection in sub-Saharan Africa with life-saving antiretroviral therapy (ART) ( 1 ). (cdc.gov)
Infection with genital herpes simplex virus (HSV) remains a common viral sexually transmitted disease, often subclinical, and a major worldwide problem in women of reproductive age. (medscape.com)
Most individuals who are infected with HSV are unaware that they have contracted the virus, with only approximately 10-15% of infected individuals reporting recognition of their infection. (medscape.com)
Virus that contacts mucosa or disrupted skin initiates the infection. (medscape.com)
A DNA vaccine expressing consensus hemagglutinin-esterase fusion protein protected guinea pigs from infection by two lineages of influenza D virus. (cdc.gov)
Egypt reported more laboratory-confirmed cases of human infection with avian influenza virus H5N1 to the World Health Organization (WHO) between 2003 and 2015 than any other country (346 cases), with 116 deaths, giving a case fatality rate of 33.5 % (10). (who.int)
Dengue virus infection has emerged as marker in clinical practice ( 11 ). (who.int)
Human immunodeficiency virus (HIV) infection results from 1 of 2 similar retroviruses (HIV-1 and HIV-2) that destroy CD4+ lymphocytes and impair cell-mediated immunity, increasing risk of certain infections and cancers. (msdmanuals.com)
Human Immunodeficiency Virus (HIV) Infection in Infants and Children Human immunodeficiency virus (HIV) infection is caused by the retrovirus HIV-1 (and less commonly by the related retrovirus HIV-2). (msdmanuals.com)
Z ported human infections indicated that clinical characteris- ika virus (ZIKV) is a mosquito-transmitted virus in the tics of infection with ZIKV included fever, headache, mal- family Flaviviridae and genus Flavivirus . (folkhalsomyndigheten.se)
Previous outbreaks of CHIKV infection have been associated with the mosquito vector Aedes aegypti , which is also the vector of yellow fever and dengue viruses. (who.int)

Characterization of an antigenic determinant of the glycoprotein that correlates with pathogenicity of rabies virus. (microbiologyresearch.org)
Here, by systematically building mutations into the hemagglutinin (H) glycoprotein of an attenuated measles virus strain and assaying for serum neutralization, we show that virus evolution is severely constrained by the existence of numerous co-dominant H glycoprotein antigenic sites, some critical for binding to the pathogenicity receptors SLAMF1 and nectin-4. (elsevierpure.com)

citation needed] The E1 protein helps the virus attach to the membrane of the targeted cell. (wikipedia.org)
In other envelope virus the E1 protein has a similar role in helping the virus get into the cell. (wikipedia.org)
If the virus cannot make the envelope protein then it will be unable to get into the host cells. (wikipedia.org)
The herpes simplex virus type 1 (HSV-1) glycoprotein N (gN/UL49.5) is a type I transmembrane protein conserved throughout the herpesvirus family. (mdpi.com)
The surface protein gp120 (SU) attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. (antikoerper-online.de)
Surface protein gp120 (SU) may target the virus to gut- associated lymphoid tissue (GALT) by binding host ITGA4/ITGB7 (alpha-4/beta-7 integrins), a complex that mediates T-cell migration to the GALT. (antikoerper-online.de)
These glycoproteins interact with the PUUV nucleocapsid (NP) protein through their cytoplasmic tail, and this association has been suggested to be crucial to the binding of the ribonucleoprotein of the PUUV and the assembly of the virus particle (2). (mytaq.com)
Nucleotide sequence analysis of the attachment (G) glycoproteins of these two strains of PVM showed only two amino acids changes within the extracellular domain of the protein. (warwick.ac.uk)
Keeping in mind that glycoprotein is the only protein exposed on the surface of virus and is thought to be responsible for the interaction with the cell membrane, it was attempted to target glycoprotein by a ligand salviifoside A of Alangium salviifolium which blocks its active site, so that it may be possible to prevent the spread of virus into the host. (ijsr.net)
Gaoxin Li , Ling Ding , Xiaojing Ma , Qiliang Cai , Tianlei Ying , Fang Wei , 2019: Establishment of Novel Monoclonal Fabs Specific for Epstein-Barr Virus Encoded Latent Membrane Protein 1, Virologica Sinica, 34, 467-470. (virosin.org)
Here we present the structural analysis of the protein and carbohydrate components of the unbound viral attachment glycoprotein of NiV glycoprotein (NiV-G) at a 2.2-A resolution. (ox.ac.uk)
Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. (lu.se)
Expression of TAP1 is down-regulated by human Epstein-Barr virus vil-10 protein, thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules. (lu.se)

The hemagglutinin, esterase, and fusion (HEF) glycoprotein of influenza C virus possesses receptor binding, receptor destroying, and membrane fusion activities. (northwestern.edu)
The HEF-AA and HEF-Tay HEF glycoproteins bound human erythrocytes, promoted membrane fusion in a low-pH and trypsin-dependent manner, and displayed esterase activity, indicating that the HEF glycoprotein alone mediates all three known functions at the cell surface. (northwestern.edu)
Most notably, the virus genomes did not spread through fusion-generated multinuclear cells. (elsevierpure.com)
Shu-ling Zhao , Xue-juan Dai , Jian-sheng Liang , Chang-yong Liang , 2012: Surface Display of Rice Stripe Virus NSvc2 and Analysis of Its Membrane Fusion Activity, Virologica Sinica, 27, 100-108. (virosin.org)
李暐东 , 梁布锋 , 祁自柏 , 2000: Fusion Expression of Hepatitis C Virus Core Region and NS3 Region in E ．coli, Virologica Sinica, 15, 204-207. (virosin.org)
EBV, like other herpesviruses, has three glycoproteins, glycoprotein B (gB), gH, and gL, that form the core membrane fusion machinery mediating viral penetration into the cell. (cornell.edu)
One-half bind the GP2 fusion subunit, one-fourth recognize the GP1 receptor-binding subunit and the remaining fourth are specific for the assembled glycoprotein complex, requiring both GP1 and GP2 subunits for recognition. (bvsalud.org)
Identification of ephrin-B2 and ephrin-B3 as cellular receptors for these viruses has enabled the development of immunotherapeutic reagents which prevent virus attachment and subsequent fusion. (ox.ac.uk)

Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding. (lu.se)

Antigenic structure of rabies virus glycoprotein: ordering and immunological characterization of the large CNBr cleavage fragments. (microbiologyresearch.org)
The HEF cDNAs from influenza C/Ann Arbor/1/50 (HEF-AA) and influenza C/Taylor/1223/47 (HEF-Tay) viruses were cloned and expressed, and transport of HEF to the cell surface was monitored by susceptibility to cleavage by exogenous trypsin, indirect immunofluorescence microscopy, and flow cytometry. (northwestern.edu)

A novel, linear B-cell epitope has been identified at the N terminus of the rabies virus (RABV) glycoprotein. (microbiologyresearch.org)
Screening of truncated glycoprotein fragments with both mAbs confirmed the location of the epitope in the N-terminal region. (microbiologyresearch.org)
Structural and immunological characterization of a linear virus-neutralizing epitope of the rabies virus glycoprotein and its possible use in a synthetic vaccine. (microbiologyresearch.org)
Next, we show that interaction of MR235 mAb with GP exposes neutralizing epitope(s) and dramatically increases binding of RBS-specific mAbs to membrane-anchored GP, which results in enhanced virus neutralization. (nuche.org)

Lack of a substantial reduction in serum neutralization of mutant measles viruses that retain even one of the co-dominant antigenic sites makes evolution of pathogenic measles viruses capable of escaping serum neutralization in vaccinated individuals extremely unlikely. (elsevierpure.com)

This helps the virus relocate to the surface of lipid droplets. (wikipedia.org)
The two types are differentiated by glycoproteins on the lipid bilayer envelope. (medscape.com)

Rabies virus antigenicity: an overview. (microbiologyresearch.org)
Rabies virus glycoprotein. (microbiologyresearch.org)
Rabies virus glycoprotein is a trimer. (microbiologyresearch.org)
Rabies Virus Glycoprotein (RABV Gl. (gentaur.co.uk)
The ligand salviifoside A of Alangium salviifolium was retrieved from Pubchem and docked with modelled Rabies Virus Glycoprotein (RVG). (ijsr.net)
Rabies is caused by a neurotropic virus of the family Rhabdoviridae, genus Lyssavirus, subgroup rabies virus. (medscape.com)
Human-to-human rabies virus transmission via saliva is theoretically possible. (medscape.com)

To assess this conjecture, we generated fusogenic adenoviruses that express a balanced ratio of the F and H glycoproteins of measles virus. (elsevierpure.com)
After centuries of pestilence and decades of global vaccination, measles virus (MeV) genotypes capable of evading vaccine-induced immunity have not emerged. (elsevierpure.com)

Crystal structure and carbohydrate analysis of Nipah virus attachment glycoprotein: a template for antiviral and vaccine design. (ox.ac.uk)

ABSTRACT Surveillance for avian influenza viruses in Egyptian poultry has been conducted since 2009. (who.int)

Influenza D virus (IDV) is a new member of influenza virus that uses cattle as the primary reservoir and infects multiple agricultural animals. (flu.org.cn)
Two lineages of influenza D virus (IDV) have been found to infect cattle and promote bovine respiratory disease complex, one of the most commonly diagnosed causes of morbidity and mortality within the cattle industry. (cdc.gov)

The expression of the major glycoprotein, gp71, of murine leukemia virus was studied on the surfaces of a variety of normal murine cell lines with a monospecific rabbit antiserum raised against purified Friend murine leukemia virus gp71. (duke.edu)

Molecular interactions of hepatitis B virus nucleocapsid and envelope peptides with HLA-DR1,-DR3,-DR7 and-DR13 glycoproteins. (ox.ac.uk)

We determined the frequency of different serotypes of dengue virus to highlight its hyperendemicity in Rawalpindi, Pakistan. (who.int)
Dengue virus is transmitted to was approved by the Ethics Committee borne viral diseases worldwide ( 1 ). (who.int)
50-100 million cases of dengue fever brate hosts of dengue virus in nature cessed by multiplex polymerase chain and 500 000 of dengue haemorrhagic are humans and several species of Asian reaction (PCR) in which the presence fever (DHF) reported annually ( 4 ). (who.int)

Other hantaviruses, including Andes virus (ANDV) and Sin Nombre virus, cause a distinct zoonotic disease, hantavirus cardiopulmonary syndrome (HCPS). (pasteur.fr)
Like other hantaviruses, the PUUV glycoprotein is synthesized as a precursor that is posttranslationally processed into two glycoproteins G1 (Gn) and G2 (Gc). (mytaq.com)
Hantaviruses are RNA zoonotic viruses that are transmitted to humans from rodent hosts. (medscape.com)

However, closely related strains (Bayou and Black Creek Canal viruses), found in the southeastern United States, may produce a variant of the syndrome that is characterized by a greater degree of renal failure. (medscape.com)
In this article we discuss the threat to this region that is posed by the recent evolution of the E1:A226V mutant strains of chikungunya virus (CHIKV). (who.int)

In the wild, many small rodents (eg, voles, white-footed deer mice) also transmit the virus. (medscape.com)

These results suggest possible pathways of virus-host interaction and strategies for the optimization of recombinant vaccines. (ox.ac.uk)
The subclades of H5N1 viruses in Egypt are antigenically distinct and most vaccines used are no longer antigenically matched (2,9). (who.int)

Recombinant Glycoprotein E (gE) of Pseudorabies Virus produced in E. coli. (creativebiomart.net)
Nairobi Sheep Disease Virus Glycoprotein Gc, Human Fc-Tag (HEK293) (100µg) (Special Terms Apply*) (QTXAG-698-100) is a recombinant Nairobi Sheep Disease Virus (NSDV) glycoprotein Gc, expressed in HEK293 cells and purified by affinity chromatography. (quadratech.co.uk)
A recombinant Nairobi Sheep Disease Virus (NSDV) glycoprotein Gc, expressed in HEK293 cells and purified by affinity chromatography. (quadratech.co.uk)

It was isolated from an infected Oligoryzomys longicaudatus rodent in Chile, and is highly similar to the Sin Nombre virus (SNV). (mytaq.com)
hivernale 2014-2015, le virus H5N1 a considérablement circulé dans les élevages de volailles, entraînant un nombre d'infections sans précédent chez l'homme. (who.int)
The Sin Nombre virus (SNV) is the Hantavirus species primarily responsible for HPS. (medscape.com)

Here we show that a truncated form of HveC directly binds to HSV glycoprotein D (gD) in solution and at the surface of virions. (nih.gov)
Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) binds to its cellular receptor, herpesvirus entry mediator (HVEM), to enter into activated T cells. (molcells.org)
Inhibited by human adenovirus e3-19k glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association. (lu.se)

Oral, nasal, and rectal swabs were collected from nonhuman primates and virus was quantitated. (infectiousdiseaseadvisor.com)

Comparison with its ephrin-B2-bound form reveals that conformational changes within the envelope glycoprotein are required to achieve viral attachment. (ox.ac.uk)

Screening of a phage-display library demonstrated that two glycoprotein-specific mAbs recognized a conserved sequence, WxxxDI, which aligned between aa 14 and 19 of the mature glycoprotein. (microbiologyresearch.org)
Notably, of the 16 mAbs that neutralize LASV, 13 require the assembled glycoprotein complex for binding, while the remaining 3 require GP1 only. (bvsalud.org)

Pseudorabies virus glycoprotein E (PRV gE) has been recognized as a suitable diagnostic antigen for pseudorabies. (creativebiomart.net)
Comparisons with homologous HSV-2 gH/gL and partial pseudorabies virus gH structures support the domain boundaries determined for the EBV gH/gL structure and illustrate significant differences in interdomain packing angles. (cornell.edu)

Description: Andes virus (ANDV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). (mytaq.com)
Description: Puumala virus (PUUV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) and is highly homologous to the protype hantavirus Hantaan virus (1). (mytaq.com)
CMV shares many attributes with other herpes viruses, including genome, virion structure, and the ability to cause latent and persistent infections. (medscape.com)
CMV has the largest genome of the herpes viruses. (medscape.com)
Retroviruses are enveloped RNA viruses defined by their mechanism of replication via reverse transcription to produce DNA copies that integrate into the host cell's genome. (msdmanuals.com)

Glycoprotein B (gB) is the most conserved component of the complex cell-entry machinery of herpes viruses. (cornell.edu)

One of them was capable of neutralizing virus infectivity and inhibiting haemagglutination, while the other had no significant neutralizing or haemagglutination-inhibiting capability, but did inhibit virus-mediated haemolysis. (microbiologyresearch.org)

Surveillance for avian influenza viruses must continue in Egypt to monitor further developments in H5N1 circulation in poultry. (who.int)

The role of individual oligosaccharide chains in the activities of the HN glycoprotein of Newcastle disease virus. (umassmed.edu)

Bovine Respiratory Syncytial Virus (BRSV) was first discovered in the 1970s and is now considered a principal pathogen implicated in the disease complex. (alliedacademies.org)
RSV is a 100-350 nm enveloped virus belonging to the Paramyxoviridae ,genus Pneumovirus, that causes minor respiratory infections in adults and bronchitis and bronchopneumonia in children. (bio-rad-antibodies.com)
The disease spreads by droplets generated by infected respiratory disease (the SARS virus in 2002-2003 and the people during sneezing and coughing. (bvsalud.org)

Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex. (cornell.edu)

Two members of the paramyxovirus family, Nipah virus (NiV) and Hendra virus (HeV), are recent additions to a growing number of agents of emergent diseases which use bats as a natural host. (ox.ac.uk)

On arrival at lymphoid tissues, intact virions recycle back to DCs' cell surface allowing virus transmission to CD4+ T-cells. (antikoerper-online.de)
The gp120-gp41 heterodimer allows rapid transcytosis of the virus through CD4 negative cells such as simple epithelial monolayers of the intestinal, rectal and endocervical epithelial barriers. (antikoerper-online.de)
Binding to these alternative receptors allows the rapid transcytosis of the virus through the epithelial cells. (antikoerper-online.de)
On the entry of Semliki virus into BHK-21 cells. (microbiologyresearch.org)
Scholars@Duke publication: Immunofluorescent analysis of expression of the RNA tumor virus major glycoprotein, gp71, on the surfaces of normal murine cells. (duke.edu)
Moreover, CAR-grafted T cells were capable of lysing target cells of both hepatic and non-hepatic origin expressing on their surface the HCV/E2 glycoproteins of the most clinically relevant genotypes, including 1a, 1b, 2a, 3a, 4 and 5. (uninsubria.it)
BACKGROUNDNK cells are activated by innate cytokines and viral ligands to kill virus-infected cells. (ox.ac.uk)
The Epstein-Barr virus (EBV) is a γ-herpesvirus that infects B cells and epithelial cells and that has been linked to malignancies in both cell types in vivo. (cornell.edu)

A systematic review of studies conducted in sub-Saharan Africa suggests higher than expected rates of false positive human immunodeficiency virus (HIV) diagnosis (false diagnosis) using rapid tests. (cdc.gov)
The other family members include herpes simplex virus type 1 (HSV-1 or HHV-1) and herpes simplex virus type 2 (HSV-2 or HHV-2), varicella zoster virus (VZV), human herpes virus (HHV)-6, HHV-7, and HHV-8. (medscape.com)
Panel on Sexually Transmitted Infections including those due to Human Immunodeficiency Virus, was posted on the WHO web site in February 2006 for a discussion and submission of comments by Member States. (who.int)
Human immunodeficiency virus (HIV) is a retrovirus. (msdmanuals.com)

E1 is one of two subunits of the envelope glycoprotein found in the hepatitis C virus. (wikipedia.org)

Anatomy14

Organisms96

Diseases12

Chemicals and Drugs72

Analytical, Diagnostic and Therapeutic Techniques and Equipment18

Phenomena and Processes47

Disciplines and Occupations1

Information Science4

Health Care1

Antibody8

Proteins8

Ebola15

Vesicular stoma2

Antibodies18

Envelope glycoproteins3

Controlling the low-pH-ind1

Epitopes3

Spike Glycoprotein2

Surface Glycoprotein1

Major glycoproteins2

Spikes3

Infection17

Pathogenicity2

Protein13

Fusion8

Peptide1

Cleavage2

Epitope4

Antigenic1

Lipid2

Rabies7

Measles virus2

Vaccine1

Abstract1

Influenza D Virus2

Murine leuke1

Nucleocapsid1

Dengue virus3

Hantaviruses3

Strains2

Mice1

Vaccines2

Recombinant3

Nombre3

Binds3

Nonhuman primates1

Attachment1

MAbs2

Pseudorabies2

Genome5

Herpes viruses1

Infectivity1

Avian influenza viruses1

Newcastle1

Respiratory3

Complex1

Nipah Virus1

Cells8

Human4

Subunits1