• A disinfectant is a chemical substance or compound used to inactivate or destroy microorganisms on inert surfaces. (wikipedia.org)
  • Low level disinfectant means a disinfectant that rapidly kills most vegetative bacteria as well as medium-sized lipid containing viruses, when used according to labelling. (wikipedia.org)
  • Enveloped viruses are relatively easy to kill compared to non-enveloped viruses, as the outer layer is easily damaged by most environmental disinfectants, provided the disinfectant is used in accordance with label directions. (tga.gov.au)
  • The MIC analyses revealed that 118 isolates (50%) were resistant to quaternary ammonium compound-based disinfectant benzalkonium chloride (BC). (nofima.no)
  • Quaternary ammonium salt disinfectant is a cationic surfactant, which can be combined with anionic surfactant to reduce the effective concentration of quaternary ammonium salt disinfectant. (labinsights.nl)
  • Disinfectant - A chemical used to destroy many microorganisms and viruses. (easynotecards.com)
  • End-users in Europe are likely to exhibit traction for 50% benzalkonium chloride due to its prevalence as a disinfectant, preservative and antiseptic in various personal care products and drugs. (gcimagazine.com)
  • Finally, a notable use of ammonium quaternary salt as a disinfectant solubilizing agent and antiseptic in products including soaps, drugs, tablets and floor cleaners will solidify the position of North America in the pharmaceutical sector. (gcimagazine.com)
  • citation needed] Bacterial endospores are most resistant to disinfectants, but some fungi, viruses and bacteria also possess some resistance. (wikipedia.org)
  • treated samples of the novel coronavirus with benzalkonium chloride, which is commonly used in alcohol-free hand sanitizers, and several other quaternary ammonium compounds regularly found in disinfectants. (fda.gov)
  • Disinfectants containing ≥ 70% alcohol, quaternary ammonium compounds (such as benzalkonium chloride) or diluted household bleach (including products containing sodium hypochlorite) are suitable for use. (tga.gov.au)
  • Disinfectants are liquids, sprays and wipes that are designed for use on surfaces to kill germs (microorganisms such as bacteria and viruses). (tga.gov.au)
  • keep in mind that hospital grade disinfectants with claims against viruses, and products intended to be used to clean or disinfect medical devices, should be listed on the Australian Register of Therapeutic Goods (ARTG). (tga.gov.au)
  • The American Veterinary Medical Association (AVMA) notes that "In veterinary, boarding, and shelter facilities, the canine influenza virus appears to be easily killed by disinfectants commonly used in those facilities, such as quaternary ammonium compounds (eg, benzalkonium chloride), aldehydes, potassium peroxymonosulfate, phenols and bleach (1:30 dilution) solutions. (benzarid.com)
  • Because disinfectants have been essential during the COVID-19 pandemic, the global demand for benzalkonium chlorides (BACs) has significantly increased. (eeer.org)
  • Quaternary ammonium compounds (QACs) have been widely used as cationic surfactants for fabricating industrial products, such as antimicrobial soap, disinfectants, detergents, fabric softeners, preservatives, and pest control products since 1935 [ 1 ]. (eeer.org)
  • Quaternary ammonium compounds (QACs) are commonly used in a variety of consumer and commercial products, typically as a component of disinfectants. (bvsalud.org)
  • The quaternary ammonium compounds are widely used as disinfectants. (rrsmed.ir)
  • Disadvantages: Quaternary ammonium salt disinfectants are low-efficiency disinfectants. (labinsights.nl)
  • Since organic substances, such as serum, can reduce the bactericidal concentration of quaternary ammonium salts, organic substances on the surface of the object must be removed before disinfection with quaternary ammonium salt disinfectants. (labinsights.nl)
  • In the process of using quaternary ammonium salt disinfectants, such substances should be avoided. (labinsights.nl)
  • Quaternary ammonium salt disinfectants are easily affected by factors such as pH, water quality, temperature, etc., and can exhibit better antibacterial and bactericidal effects in an alkaline environment. (labinsights.nl)
  • Some quaternary ammonium salt disinfectants, such as benzalkonium bromide, can react with metal ions in high-hardness water to reduce the effective concentration of quaternary ammonium salt, thus failing to achieve the corresponding disinfection effect. (labinsights.nl)
  • Therefore, when preparing quaternary ammonium salt disinfectants, distilled water should be used and the pH should be adjusted to alkaline in order to achieve the best disinfection effect. (labinsights.nl)
  • The antiseptics that applied to the body and disinfectants that applied to nonliving surfaces must have the potential of killing living microbes like bacteria and inactivating nonliving microbes like viruses. (utopiaeducators.com)
  • Among the BACs reported to date, benzyl dimethyl dodecyl ammonium chloride (BAC 12 ), benzyl dimethyl tetradecyl ammonium chloride (BAC 14 ), and benzyl dimethyl hexadecyl ammonium chloride (BAC 16 ) have been widely used because of their high bioavailability [ 4 ]. (eeer.org)
  • The newer quaternary ammonium compounds (i.e., fourth generation), referred to as twin-chain or dialkyl quaternaries (e.g. didecyl dimethyl ammonium bromide and dioctyl dimethyl ammonium bromide), purportedly remain active in hard water and are tolerant of anionic residues. (rrsmed.ir)
  • 68424-85-1 / 8001-54-5 is a broad spectrum, fast acting biocide based on the active matter alkyl(C12-16)dimethylbenzyl ammonium chloride. (zxchem.com)
  • Chemically, the quaternaries are organically substituted ammonium compounds in which the nitrogen atom has a valence of 5, four of the substituent radicals (R1-R4) are alkyl or heterocyclic radicals of a given size or chain length, and the fifth (X-) is a halide, sulfate, or similar radical. (rrsmed.ir)
  • These are basically chemicals with extensive applications owing to wide-spectrum antimicrobial properties against viruses, fungi, and bacteria. (asdreports.com)
  • Each compound exhibits its own antimicrobial characteristics, hence the search for one compound with outstanding antimicrobial properties. (rrsmed.ir)
  • It has very good antibacterial, antifungal and antimicrobial properties which make it very useful against a large range of parasites, infections and viruses. (brainreference.com)
  • The antimicrobial properties against viruses, fungi and bacteria have encouraged the market participants to up the uptake of benzalkonium chloride. (gcimagazine.com)
  • Although we have known for well over a century how microorganisms - bacteria, viruses, fungi, protozoans and parasitic worms - can be transmitted via infected hands, the actual practice of hand hygiene has not been optimal, even among medical professionals. (initial.com)
  • They are still unable to kill microorganisms such as fungi, tuberculosis, hydrophilic viruses, and bacterial spores. (labinsights.nl)
  • Germicide - KIlls microorganisms and viruses. (easynotecards.com)
  • The antibacterial effect of 0.13% benzalkonium chloride against the biological indicators was observed after five minutes in direct exposure, while cetylpyridinium chloride and chlorhexidine gluconate had an antibacterial effect against all the microorganisms after 10 minutes. (bvsalud.org)
  • Considering the product reduces the growth of microorganisms on skin , the demand for benzalkonium chloride in India and China has become noticeable in cosmetics and personal care products as well, including skin cleansers, shampoos, personal cleansing products and eye makeup. (gcimagazine.com)
  • 12 It is also susceptible to other lipid solvents including hydrogen peroxide, alcohol (ethanol or isopropyl alcohol), sodium hypochlorite (bleach), benzalkonium chloride (found in most Lysol products) and peroxyacetic acid (found in surface cleaners and sanitizers) among others. (ncceh.ca)
  • Halogen compounds are broad spectrum compounds that are considered low toxicity, low cost and easy to use. (brainkart.com)
  • In addition, QACs have been recently recognized as capable of inactivating corona viruses. (eeer.org)
  • Benzalkonium chlorides (BACs) are well-known QACs. (eeer.org)
  • During the COVID-19 pandemic, QACs became one of the primary agents utilized to inactivate the SARS-CoV-2 virus on surfaces. (bvsalud.org)
  • Quaternary ammonium compounds (QACs) are a kind of widely used cationic surfactants. (labinsights.nl)
  • The properties of QACs are determined by the structure and properties of their substituted R groups, which can be divided into four categories, namely, alkyltrimethylammonium compounds (ATMACs) and dialkyldimethlammonium compounds (DADMACs), benzylalkyldimethylammonium compounds (BACs) and heterocyclic ammonium compounds (HACs). (labinsights.nl)
  • QACs can kill most bacterial propagules and fungal viruses. (labinsights.nl)
  • If classified by anion, QACs can be grouped into: halide quaternary ammonium salts, acid radical quaternary ammonium salts, polyquaternium, quaternary ammonium hydroxide, and quaternary phosphonium compounds. (labinsights.nl)
  • Recent reports have indicated that the demand for BACs will increase during the severe acute respiratory syndrome-Coronavirus-2 (SARS-CoV-2) pandemic [ 2 ] because BACs effectively inactivate the SARS-CoV-2 virus [ 7 ]. (eeer.org)
  • Such synthetic compounds like benzalkonium chloride and benzethonium chloride are used in the cosmetics industry and are very toxic antimicrobial preservatives. (brainreference.com)
  • Benzalkonium chloride is a quaternary ammonium compound used in pharmaceutical formulations as an antimicrobial preservative in applications similar to other cationic surfactants. (atamankimya.com)
  • Iodine compound are broad spectrum and considered effective for a variety of bacteria, mycobacteria, fungi and viruses. (brainkart.com)
  • Low concentrations (2-500ppm) are active against vegetative bacteria, fungi and most viruses. (brainkart.com)
  • It has antioxidant properties and is used for cleaning the body of harmful bacteria, viruses, infection, parasites and fungi, and for promoting and protecting the immune system. (brainreference.com)
  • Although many EOs have been studied with respect to their effects on bacteria and fungi, most scientific research on viruses has been done on Herpes viruses. (thegreentimes.co.za)
  • Sodium lauryl sulfate (SLS) and sodium laureth sulfate (SLES) or commonly labeled as Sodium lauryl sulfate, sodium laureth sulfate, sodium salt, ammonium laureth sulfate, sodium n-dodecyl sulfate, dodecyl sulfate, and sodium dodecyl sulfate. (healthyplanetproducts.net)
  • The global benzalkonium chloride market is expected to pick up significant momentum in terms of growth over 2021-2027. (asdreports.com)
  • The global benzalkonium chloride market is bifurcated into various segments in terms of type, applications, end-use, and regional landscape. (asdreports.com)
  • From a regional frame of reference, LATAM benzalkonium chloride market size is expected to grow over by $90 million by the end of 2027. (asdreports.com)
  • Graphical Research predicts the benzalkonium chloride market is likely to grow with pressing demand for the compound in the pharmaceutical, cosmetics, health care and other industries. (gcimagazine.com)
  • The cosmetic industry in Europe is also expected to drive growth in the benzalkonium chloride market as it has gained ground as a preservative in products including shampoos, sunscreen lotions, lipsticks and eye makeup products. (gcimagazine.com)
  • Quaternary ammonium compounds or benzalkonium chloride is widely used as anti-static, preservative and emulsifier in the coatings industry such as electronics, wood treatment, and paints among others. (asdreports.com)
  • Benzalkonium chloride is widely used as a general microbicide for slime control as well as odor management in pulp mills. (asdreports.com)
  • In this study, we examined the effects of a widely used QAC (benzalkonium chloride-C14, BAC-14) on two toxigenic Microcystis strains and one non-toxigenic freshwater Microcystis strain and carried out an analysis focused on primary, adaptive and compensatory stress responses at apical (growth and photosynthesis) and metabolic levels. (bvsalud.org)
  • NC/Nga mice were subcutaneously injected with mite allergen (Dp) to induce AD-like skin lesions (ADSLs), and an application of 0.2% (w/v) benzalkonium chloride (BZK), 10% (w/v) povidone-iodine (PVP-I), 80% (v/v) ethanol (Et-OH), or 0.5% (v/v) chlorhexidine gluconate (CHG) was applied to the ear envelope. (medsci.org)
  • Purpose: To evaluate the antibacterial effect of four oral antiseptics (two solutions of cetylpyridinium chloride, chlorhexidine gluconate and benzalkonium chloride) on facultative bacteria using two methods. (bvsalud.org)
  • As a cationic detergent in the family of quaternary ammonium compounds, benzalkonium chloride (BZK) shows strong antiseptic activity against both gram-positive and -negative bacteria. (medsci.org)
  • The trend for the compound in other regions will primarily be attributed to its use as a preservative, emulsifier and antiseptic in the manufacturing of chemical catalysts for industrial use. (gcimagazine.com)
  • The firm notes the benzalkonium chloride industry outlook is likely to remain, with the demand from pharmaceutical and chemical industries poised to surge in the next few years. (gcimagazine.com)
  • The invention relates to a novel combined disinfection and decontamination agent comprising at least one vitamin, at least one metal ion, at least one active-surface compound, and at least one further antimicrobial active substance. (justia.com)
  • The invention has as subject matter a disinfection and decontamination agent containing at least one vitamin, at least one metal ion, at least one surface-active compound and at least one antimicrobial active substance. (justia.com)
  • The World Health Organization (WHO) showed the importance of hand hygiene and disinfection practices to fight the virus and reduce its potential. (utopiaeducators.com)
  • Also, high-touched surfaces disinfection in non-healthcare settings is recommended by the WHO to reduce the potential of COVID-19 virus, such as door and window handles in homes, markets, and schools. (utopiaeducators.com)
  • SARS-CoV-2 genetic materials are enveloped by a fatty layer that is susceptible to soaps and detergents that can deactivate the virus by tearing apart its outer layer. (ncceh.ca)
  • The compound acts as a cationic surfactant , biocide and phase transfer agent in applications such as preservatives for the foods industry, emulsifying agents and detergents. (gcimagazine.com)
  • As well as being a powerful biocide, killing virus and infectious bacteria, ozone has been proven to have a positive de-scaling effect. (mellifiq.com)
  • Health-care-associated infections have been reported from contaminated quaternary ammonium compounds used to disinfect patient-care supplies or equipment, such as cystoscopes or cardiac catheters. (rrsmed.ir)
  • With the exception of some spore-forming bacteria and envelope-lacking viruses, ethanol shows a broad antibacterial and antiviral spectrum. (medsci.org)
  • Water treatment facilities - Drinking water is free of gastrointestinal pathogens including bacteria, protozoa, and viruses. (easynotecards.com)
  • GSE liquid concentrate is very effective against pathogens due to its natural quaternary compounds which are molecularly similar to the ones that belong to a family of synthetic quaternary ammonium. (brainreference.com)
  • GSE features the best of both worlds: the quaternary compounds derived from grapefruit exhibit broad-spectrum antimicrobial activity, while evidencing none of the toxic side effects of chemically derived quaternaries. (naturalhealthgarden.ca)
  • Grapefruit seed extract is being used successfully in humans and animals alike to eliminate many types of internal and external infections caused by many types of parasites (single- and multicelled), viruses, bacteria, and fungus. (naturalhealthgarden.ca)
  • Nutribiotic's Maximum GSE Liquid Concentrate contains Citricidal, which is a natural quaternary compound synthesized from the seed and pulp of grapefruit that has been proven highly effective in numerous applications. (brainreference.com)
  • While Grapefruit Seed Extract is molecularly similar to these compounds, there are some profound differences in structure and function. (brainreference.com)
  • Selected compounds were formulated as solutions for nebulization and, after being characterized in terms of aerosolization performance and droplet size distribution, their efficacy was assessed in vivo using the K18 human (h)ACE2 transgenic mouse model of SARS-CoV-2 infection. (bvsalud.org)
  • However, given that viruses are constantly changing, it is possible that canine influenza strains could change and infect humans. (benzarid.com)
  • Humans are the main source of the virus transmission. (utopiaeducators.com)
  • Our environmentally friendly cleaner removes bacteria and viruses all while maintaining its natural soap formula. (healthyplanetproducts.net)
  • This chemical interaction is thought to enable soaps to break apart the virus envelope and neutralise these types of virus . (initial.com)
  • They are formed by the substitution of hydrogen atoms of ammonium groups by alkanes or aromatic hydrocarbon groups. (labinsights.nl)
  • The disease caused by the virus has been named "Coronavirus Disease 2019" (COVID-19). (fda.gov)
  • The primary mode of human-to-human transmission for SARS-CoV-2, the virus responsible for coronavirus disease (COVID-19), is via direct contact with an infected person and their respiratory droplets, expelled during coughing, sneezing, speaking, or breathing. (ncceh.ca)
  • Our extra-strength formula is Quaternary Ammonium Compound based, and kills 99.9% of germs. (zehnxwipes.com)
  • Soap molecules have a hydrophilic (water loving) end that is attracted to water and a hydrophobic (water hating) end that is attracted to lipids - such as those in the virus envelope. (initial.com)
  • they are not sporicidal and generally not tuberculocidal or virucidal against hydrophilic (nonenveloped) viruses. (rrsmed.ir)
  • The active ingredient used in these wipes is Benzalkonium Chloride. (zehnxwipes.com)
  • Cleaning with products containing soap or detergent reduces germs on surfaces by removing contaminants and may also weaken or damage some of the virus particles, decreasing infection risk from surfaces. (ucanr.edu)
  • Alcohols can destroy the lipid component of enveloped viruses. (brainkart.com)
  • Enveloped viruses such as influenza ( Orthomyxoviridae ) and coronaviruses ( Coronaviridae ) have a capsule-like outer envelope composed of a lipid bilayer and a large number of proteins. (initial.com)
  • 7 , 8 Other studies of coronaviruses have found that viruses can remain viable for up to nine days on non-porous surfaces such as metal, glass, or plastic. (ncceh.ca)
  • A total of 61 strains of Staphylococcus aureus and 177 coagulase-negative staphylococcal strains were isolated from the blood of patients with bloodstream infections and from the skin of both children under cancer treatment and human immunodeficiency virus-positive patients. (nofima.no)
  • Attempts to reproduce the manufacturers' bactericidal and tuberculocidal claims using the AOAC tests with a limited number of quaternary ammonium compounds occasionally have failed. (rrsmed.ir)
  • Canine influenza virus can survive on hands for 12 hours, on clothing for 24 hours, and on hard surfaces for up to 48 hours. (benzarid.com)
  • But viruses can be picked up by touching the nose or mouth, respiratory droplets launched into the air or from contaminated surfaces. (initial.com)
  • 9 Interventions to reduce the transmission of SARS-CoV-2 via contact routes must include frequent cleaning and disinfecting to reduce viability of the virus on potentially contaminated surfaces. (ncceh.ca)
  • While the SARS-CoV-2 virus is primarily airborne, it is possible for people to be infected by contacting contaminated surfaces. (ucanr.edu)
  • When no people with confirmed or suspected COVID-19 infections are known to have been in a space, cleaning once a day is usually enough to sufficiently remove virus particles that may be on surfaces and help maintain a healthy facility. (ucanr.edu)
  • This decontamination solution consisting of a vitamin, a metal ion and a surface-active compound displays a good nucleic acid degradation while simultaneously gently treating the surfaces. (justia.com)
  • Hands are more likely to host bacteria, which can live on and in the skin, than viruses, which cannot remain viable for long outside a living cell. (initial.com)