• Vincristine and vinblastine are most commonly used, and new drugs such as etoposide, teniposide, and vinorelbine are being used in human medicine but have not yet received widespread use in veterinary oncology. (vin.com)
  • Vincristine, also known as leurocristine and marketed under the brand name Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. (wikipedia.org)
  • Vinblastine and Oncovin - vincristine) have been reported to be highly effective against breast cancer as well as many other types of cancer. (shu.edu)
  • The U.S. Food and Drug Administration today approved Marqibo (vincristine sulfate liposome injection) to treat adults with a rare type of leukemia called Philadelphia chromosome negative (Ph-) acute lymphoblastic leukemia (ALL). (news-medical.net)
  • Marketed formulations contain vincristine sulfate ( PubChem CID 249332 ). (guidetoimmunopharmacology.org)
  • Vincristine is delivered via intravenous infusion for use in various types of chemotherapy regimens. (wikipedia.org)
  • The main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. (wikipedia.org)
  • Chemotherapy-induced peripheral neuropathy can be severe, and may be a reason to reduce or avoid using vincristine. (wikipedia.org)
  • Vincristine lipid complex should be given only under the supervision of a doctor with experience in the use of chemotherapy medications. (medlineplus.gov)
  • It is extremely important that the intravenous needle delivering vincristine be properly positioned in the vein. (medicap.com)
  • Left top) Catharanthus roseus, aka the Madagascan Periwinkle, a member of the Vinca plant family, is the source of the cancer drug vincristine (Right top) Nice structure, huh? (acsh.org)
  • New York, NY -- ( SBWIRE ) -- 02/02/2019 -- Global Vincristine market size will increase to Million US$ by 2025, from Million US$ in 2017, at a CAGR of during the forecast period. (sbwire.com)
  • Vincristine works partly by binding to the tubulin protein, stopping the tubulin dimers from polymerizing to form microtubules, causing the cell to be unable to separate its chromosomes during the metaphase. (wikipedia.org)
  • The toxicity is why you see vinca commonly planted in areas where deer eat other flowers. (acsh.org)
  • Your doctor may tell you to take a stool softener or laxative to help prevent constipation during your treatment with vincristine lipid complex. (medlineplus.gov)
  • A downside, however, to Vincristine is that it does not only affect the division of cancer cells. (wikipedia.org)
  • Vincristine is also being studied in the treatment of other types of cancer. (news-medical.net)
  • Cycling cells are required for vincristine to kill cancer cells efficiently. (uni-muenchen.de)
  • Vincristine treats certain types of cancer. (medicap.com)
  • Vincristine has been use in combination with other medicines to treat certain types of cancer. (medicap.com)
  • Vincristine has been use in combination with other medicines to treat the following cancers: non-Hodgkin's lymphoma, Hodgkin's lymphoma, acute lymphoblastic leukemia (ALL), Wilms' tumor (a form of pediatric kidney cancer), rhabdomyosarcoma, and neuroblastoma. (medicap.com)
  • The purpose of this work was to document the efficacy and side effects of vincristine sulphate treatment on TVTc. (vin.com)
  • One of the first symptoms of peripheral neuropathy is foot drop: A person with a family history of foot drop and/or Charcot-Marie-Tooth disease (CMT) should avoid vincristine. (wikipedia.org)
  • With repeated doses of vincristine, you may feel symptoms of peripheral neuropathy (tingling sensation and numbness in the fingers and toes). (medicap.com)
  • Vincristine-induced neuropathy is the main dose-limiting side effect. (wikipedia.org)
  • The vincristine administrations, at the dose of 0.5 mg/m 2 of body surface (IV), were done considering all the manufacturers' warnings recommendations. (vin.com)
  • Vincristine sulphate, at the dose of 0.5 mg/m 2 of body surface (IV), on 7-14 days intervals, reveal high efficiency (86.6%) for TVTc treatment. (vin.com)
  • Most people experience some side effects from vincristine treatment. (wikipedia.org)
  • Vincristine lipid complex may cause side effects. (medlineplus.gov)
  • Vincristine is safe for most patients, but potential side effects can occur, as gastrointestinal alterations, myelosuppression and extravasation injury. (vin.com)
  • Before the therapy sections it is necessary to execute the clinical evaluation, the cytological exam and the complete blood count for monitoring the side effects related to vincristine. (vin.com)
  • Vincristine is the active ingredient in a drug used to treat acute leukemia. (news-medical.net)
  • There is an attempt to overcome resistance by the addition of derivatives and substituents to the vincristine molecule. (wikipedia.org)
  • It is important for you to tell your doctor how you are feeling during your treatment with vincristine lipid complex. (medlineplus.gov)
  • One tumor (6.6%) was refractory to vincristine, while at the treatment beginning we observed a mass reduction. (vin.com)
  • Vincristine has been proven hazardous and should be avoided by all CMT patients, including those with no symptoms. (asociatiacmt.ro)
  • Vincristine can cause tingling sensation and numbness in the fingers and toes. (medicap.com)
  • Toxicities associated with vincristine are mild, but perivascular reaction can be a problem. (vin.com)
  • Vincristine lipid complex should be administered only into a vein. (medlineplus.gov)
  • Vincristine lipid complex comes as a liquid to be injected intravenously (into a vein) over 1 hour by a doctor or nurse in a medical facility. (medlineplus.gov)
  • [3] If vincristine is used alone, it is given once a week strictly into a vein. (mdwiki.org)
  • Vincristine was an effective chemotherapeutic agent for genital TVTc, showing tumours totally regression in 13 dogs, among them the therapy was also efficient for one case of diffuse cutaneous TVTc. (vin.com)