• viral
  • Altogether our results underscore the importance of stratification based on the size and differentiation of the CMV-specific memory T cell pools for the impact on immune senescence, and indicate that reduction of the latent/lytic viral load can be beneficial to diminish CMV-associated immune senescence. (frontiersin.org)
  • Moreover, the major difficulty in developing vaccines and anti-viral drugs is due to viral variation. (wikipedia.org)
  • They then introduced into the cultures chemicals which they thought might inhibit viral activity, and observed whether the level of virus in the cultures rose or fell. (wikipedia.org)
  • Viral life cycles vary in their precise details depending on the type of virus, but they all share a general pattern: Attachment to a host cell. (wikipedia.org)
  • Release of viral genes and possibly enzymes into the host cell. (wikipedia.org)
  • Replication of viral components using host-cell machinery. (wikipedia.org)
  • Release of viral particles to infect new host cells. (wikipedia.org)
  • The RNCs are transported through the cytosol for packaging into virions through association with viral matrix proteins at cell membranes. (frontiersin.org)
  • The idea of turning the humoral immune system inside out ( 1 ) as a means of intracellular immunization ( 2 ) was first demonstrated by Antman and Livingston in 1980 ( 3 ) where IgG specific for SV40 T antigens were capable of inhibiting viral DNA synthesis following microinjection into cells permissive for replication. (frontiersin.org)
  • ACIP
  • This report updates the 1993 recommendations by CDC's Advisory Committee on Immunization Practices (ACIP) regarding the prevention of Japanese encephalitis (JE) among travelers (CDC. (cdc.gov)
  • In February 2006, a live, oral, human-bovine reassortant rotavirus vaccine (RotaTeq® [RV was licensed as a 3-dose series for use among U.S. infants for the prevention of rotavirus gastroenteritis, and the Advisory Committee on Immunization Practices (ACIP) recommended routine use of RV5 among U.S. infants (CDC. (cdc.gov)
  • In April 2008, a live, oral, human attenuated rotavirus vaccine (Rotarix® [RV was licensed as a 2-dose series for use among U.S. infants, and in June 2008, ACIP updated its rotavirus vaccine recommendations to include use of RV1. (cdc.gov)
  • ACIP recommends routine vaccination of U.S. infants with rotavirus vaccine. (cdc.gov)
  • This report presents the recommendations of the Advisory Committee on Immunization Practices (ACIP) for use of two rotavirus vaccines among U.S. infants: RotaTeq® (RV5) (Merck and Company, Whitehouse Station, New Jersey), which was licensed by the Food and Drug Administration (FDA) in February 2006 ( 10 ) and Rotarix® (RV1) (GlaxoSmithKline [GSK] Biologicals, Rixensart, Belgium), which was licensed by FDA in April 2008 ( 11 ). (cdc.gov)
  • immunity
  • Upon recognition of a pathogen via TLRs, the immature DCs at the site of pathogen entry undergo a maturation process during which they exit the site and migrate to the T cell-rich areas of the neighboring lymph nodes, where the mature DCs present their acquired antigens and stimulate antigen-specific T cells, thus initiating adaptive immunity and immune memory. (rupress.org)
  • antibody
  • In addition, in vivo models, particularly those engineered to knock in or knock out effector cells or effector molecules, are excellent tools for understanding antibody functions. (asmscience.org)
  • infections
  • Compared to other infections, extraordinary high memory T cell frequencies, on average ~10% of the total memory T cell compartment, are noticed in peripheral blood of healthy individuals ( 3 ). (frontiersin.org)
  • dose
  • Sera from 12-18 month-old children who received a single dose of JE-CV in a phase III study in Thailand and the Philippines (ClinicalTrials.gov NCT00735644) were randomly selected and pooled according to neutralization titer against JE-CV into eight samples. (biomedcentral.com)
  • lines
  • The cDNA-derived ZIKV replicated efficiently in a variety of cell lines, including those of both neuronal and placental origin. (asm.org)
  • serum
  • Serologic tests in which a known quantity of antigen is added to the serum prior to the addition of a red cell suspension. (labome.ru)
  • recommendations
  • This report summarizes the epidemiology of JE, describes the two JE vaccines that are licensed in the United States, and provides recommendations for their use among travelers and laboratory workers. (cdc.gov)
  • The recommendations in this report also address the maximum ages for doses, contraindications, precautions, and special situations for the administration of rotavirus vaccine. (cdc.gov)
  • among
  • However, travel-associated JE, although rare, can occur among persons of any age ( 6 --9 ). (cdc.gov)
  • basis
  • For most travelers to Asia, the risk for JE is very low but varies on the basis of destination, duration, season, and activities. (cdc.gov)
  • phase
  • Pooled specimens are homogenized in buffered saline using a mixer-mill and the aqueous phase is inoculated onto confluent Vero cell cultures (Clone E6). (jove.com)
  • areas
  • JE vaccine is not recommended for short-term travelers whose visit will be restricted to urban areas or times outside of a well-defined JEV transmission season. (cdc.gov)
  • In this download probabilistic models for nonlinear partial differential equations, we are extended evidence climate of Nel, by providing a plasma of cell effects for collaborative areas of the Nel study. (pd19.org)
  • report
  • We therefore report preliminary safety and immunogenicity results after one injection of a licensed monovalent pandemic H1N1 vaccine in the USA. (labome.ru)
  • Asia
  • JE occurs throughout most of Asia and parts of the western Pacific. (cdc.gov)