• macrophages
  • The white pulp of the spleen contains germinal centers, with lymphocytes, plasma cells, and macrophages that help coordinate the immune response and play roles in both innate and adaptive immunity. (medscape.com)
  • important
  • Recognition of this variant is important to avoid spearing the spleen during interventional procedures such as nephrostomy . (radiopaedia.org)
  • The spleen plays an important role in granulocyte homeostasis also by influencing the elimination of senescent cells and regulatory effects on granulocyte renewal in the bone marrow. (medscape.com)
  • cell
  • The spleen may be removed in other conditions (eg, hemoglobinopathies) to improve the red cell life expectancy. (medscape.com)
  • mass
  • Occasionally, the spleen may be removed to address the sheer mass effect of a massive enlargement (such as in storage disorders), which can cause mass effects. (medscape.com)