Loading...
  • studies
  • Laboratory testing to evaluate the etiology of portal hypertension (viral hepatitis panel, iron studies, alpha-1-antitrypsin, ceruloplasmin, and autoimmune markers including anti-nuclear antibody, immunoglobulin classes, smooth muscle antibodies, and antimitochondrial antibodies) was unremarkable. (gi.org)
  • Several studies have found that patients with portal hypertension develop increased blood flow to the stomach. (wikipedia.org)
  • splanchnic
  • In a model of pre-sinusoidal portal hypertension in rats, splanchnic arterial vasodilation is observed and is accompanied by a decreased contractile response to nitroprusside or isoproterenol and impaired myocyte calcium signaling, showing that portal vascular change and portosystemic shunting cause cirrhotic cardiomyopathy independent, at least in part, of parenchymal liver disease ( 8-10 ). (onlinejacc.org)
  • acute
  • However, according to retrospective data, roughly one in seven patients with portal hypertensive gastropathy will develop bleeding (either acute or chronic) attributable to the gastropathy. (wikipedia.org)
  • blood
  • 4,5 It is theorized that this pattern of atrophy and hypertrophy is due to segmental alterations in the portal blood flow to the liver secondary to venous compression by fibrosis and regenerative nodules. (jaocr.org)
  • Sinusoidal portal hypertension, in contrast, is characterized by increased hepatic sinusoidal resistance to blood flow. (onlinejacc.org)
  • Esophageal varices result from collateral portal blood flow through vessels in the stomach and esophagus (a process called portacaval anastomosis). (wikipedia.org)
  • As a result, the partial gas pressure of oxygen (pO2) and perfusion pressure of portal blood are lower than in other organs of the body. (wikipedia.org)
  • In these models, EETs prevent arterial occlusive diseases such as heart attacks and brain strokes not only by their anti-hypertension action but possibly also by their anti-inflammatory effects on blood vessels, their inhibition of platelet activation and thereby blood clotting, and/or their promotion of pro-fibrinolytic removal of blood clots. (wikipedia.org)
  • Resuscitation of all lost blood leads to increase in portal pressure leading to more bleeding. (wikipedia.org)
  • Several studies have found that patients with portal hypertension develop increased blood flow to the stomach. (wikipedia.org)
  • Biopsies of the stomach in patients with portal hypertensive gastropathy show ectatic (or dilated) blood vessels, evidence of bleeding by means of red blood cells in the lamina propria, and edema in the stomach wall. (wikipedia.org)
  • While healthy livers are predominantly oxygenated by portal blood supply, long-standing portal hypertension results in compensatory hypertrophy of and increased reliance on the hepatic artery for oxygenation. (wikipedia.org)
  • Thus, in people with advanced liver disease the shunting of portal blood away from hepatocytes is usually well tolerated. (wikipedia.org)
  • cirrhotic
  • In patients with cirrhotic livers intersinusoidal communication is disrupted such that sinusoidal pressure equilibrium cannot be maintained, and so WHVP becomes a far more accurate measure of portal venous pressure. (wikipedia.org)
  • other, less frequent causes are therefore grouped as non-cirrhotic portal hypertension. (wikipedia.org)
  • coronary
  • Cardiac hypertrophy and cardiomyocyte edema in the absence of coronary artery disease, hypertension, or valvular disease were next described in an autopsy series of subjects with cirrhosis ( 2 ). (onlinejacc.org)
  • stroke
  • Alcohol dependence is associated with hypertension, coronary heart disease, and ischemic stroke, cancer of the respiratory system, and also cancers of the digestive system, liver, breast and ovaries. (wikipedia.org)
  • Diabetes
  • This can be done in several ways, the most important being lifestyle modifications-decreasing low-density lipoprotein (LDL), quitting smoking, physical activity, and control for other risk factors including diabetes, obesity, and hypertension. (wikipedia.org)
  • tumor
  • Contrast computed tomography and/or contrast-enhanced magnetic resonance imaging of the liver is required to assess tumor and normal liver volumes, portal vein status, and extrahepatic tumor burden. (wikipedia.org)
  • Deep
  • IVC filters: Metallic filters placed in the vena cava to prevent propagation of deep venous thrombus. (wikipedia.org)
  • main
  • A complementary angio-CT allowed a better assessment of the portal system that contained some thin calcifications in the aneurysmal wall and the main portal trunk ( Figure 2 , Figure 3 , Figure 4 ). (panafrican-med-journal.com)