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  • transmission
  • Vector competence is assessed by detecting fluorescence outside the midgut or by monitoring virus transmission 7 . (jove.com)
  • Extensive field and laboratory studies done since 1945 in the Central Valley of California have more clearly defined the specific invertebrate and vertebrate hosts involved in the basic virus transmission cycle, but the overall concept remains unchanged. (ajtmh.org)
  • fevers
  • Healthy adults who become infected by the virus may experience flu-like symptoms, such as high fevers and headaches. (wikipedia.org)
  • SINV
  • We have shown that infectious virus can be cleared by the combined effects of antibody (Ab) to the SINV E2 glycoprotein and interferon (IFN)-g, through processes that do not damage the infected neurons. (grantome.com)
  • populations
  • The speed with which the disease spreads depends on the subtype of the VEE virus and the density of mosquito populations. (wikipedia.org)
  • Semliki Forest
  • The structure of the Semliki Forest virus revealed a structure that is similar to that of flaviviral glycoprotein E, with three structural domains in the same primary sequence arrangement. (wikipedia.org)
  • infectious virus
  • PKR increased levels of serum IFN and the rate of clearance of infectious virus from the brain. (pubmedcentralcanada.ca)
  • In summary, in response to SFV, PKR exerts an early antiviral effect that delays virus protein production and release of infectious virus and, whilst PKR is not required for induction of apoptosis or activation of the type I IFN response, it strongly augments the type I IFN response and contributes to clearance of infectious virus from the mouse brain. (pubmedcentralcanada.ca)
  • Transfected cells generate infectious virus particles expressing the GOI. (jove.com)
  • Detailed study of virus clearance from the CNS of immunologically normal 4-6 week-old C57BL/6 mice over 6 months has revealed 3 phases of the clearance process: 1) clearance of infectious virus, but continued high levels of viral RNA;2) gradual decrease in the amounts of viral RNA without production of infectious virus;and 3) maintenance of viral RNA at low levels with prevention of virus reactivation. (grantome.com)
  • 2) Determine the components of the immune response that decrease viral RNA in the CNS after infectious virus is cleared;and (3) Determine the role and maintenance of resident antibody-secreting cells in inhibition of virus reactivation. (grantome.com)
  • This research will determine the mechanisms required for immune-mediated non-cytolytic clearance of infectious virus and viral RNA from neurons and for prevention of virus reactivation and late neurologic disease. (grantome.com)
  • dengue virus
  • Serologic data indicated that this was the first occurrence of any dengue virus on the island for at least 25 years. (ajtmh.org)