• In the current era of mitral valvuloplasty for acquired mitral stenosis, however, residual iatrogenic ASD secondary to transseptal puncture is more common than congenital ASD, as is the combination of ASD and mitral stenosis. (medscape.com)
  • Most severe congenital heart defects have a poor prognosis if intervention is not received. (biomedcentral.com)
  • The most commonly associated clinically significant defects include patent ductus arteriosus , VSD, and aortic stenosis. (medscape.com)
  • Over the next few decades the number of patients diagnosed with aortic stenosis is expected to rise as the population ages and the use of several diagnostic tools expands. (radcliffecardiology.com)
  • This article briefly describes the prevalence, pathogenesis and clinical presentation of patients with aortic stenosis and focuses on developments in diagnostic tools, treatment strategies and treatment modalities: the use of echocardiography, tissue Doppler imaging, stress testing and biomarkers is discussed, as well as timing of surgery and the role microsimulation can play in prosthesis selection. (radcliffecardiology.com)
  • Degenerative aortic stenosis is the most common valvular heart disease in developed countries. (radcliffecardiology.com)
  • 3 As aortic valve calcification increases with age, the prevalence of aortic stenosis increases concomitantly. (radcliffecardiology.com)
  • 3,4 As the developed world population continues to age and the more widespread use of Doppler techniques results in detection of more (asymptomatic) patients, aortic stenosis constitutes a growing health burden. (radcliffecardiology.com)
  • Symptom variability is large: patients with only moderate stenosis may report symptoms, while others with a more severe stenosis may not. (radcliffecardiology.com)
  • Although approximately half of elderly patients undergoing AVR for aortic stenosis have significant concomitant coronary artery disease, angina can also occur in patients with a healthy coronary system. (radcliffecardiology.com)
  • Coarctation of the aorta may occur as an isolated defect or in association with various other lesions, most commonly bicuspid aortic valve and ventricular septal defect (VSD). (medscape.com)
  • Bicuspid aortic valve may be seen in nearly two thirds of infants with coarctation of the aorta, whereas only 30% of those who present in childhood have such an anomaly. (medscape.com)
  • Mitral valve anomalies, although less common than those of the aortic valve, are also associated with coarctation of the aorta. (medscape.com)
  • The global annual need for aortic valve replacement (AVR) is expected to triple to approximately 850,000 by 2050. (radcliffecardiology.com)
  • Some patients with coarctation of the aorta may have cerebral aneurysms, predisposing them to cerebrovascular accidents with severe hypertension later in life. (medscape.com)
  • Aortic coarctation is extremely rare in patients with severe right ventricular outflow tract obstructions such as tetralogy of Fallot and pulmonary atresia with intact ventricular septum . (medscape.com)