• Other segmented viral genomes include those of reoviruses, arenaviruses, and bunyaviruses. (virology.ws)
  • This sequence data will be used to identify conserved regions of the viral genomes which produce MLN , and artificial mircroRNAs will be designed to target these regions and inserted into maize. (cam.ac.uk)
  • Phylogenetic analysis of 14 complete viral genomes determined by sRSA suggested multiple introductions of viruses into the region. (cipotato.org)
  • Considering its epidemiological importance, efforts have been directed towards understanding various aspects of DENV biology, which have been facilitated by the development of different molecular strategies for engineering viral genomes, such as reverse genetics approaches. (bvsalud.org)
  • Sequence analysis of viral genomes presented high similarity with dengue serotype 1 viruses circulating in South-eastern Asia. (who.int)
  • The ongoing annotation of these genomes should spark a new wave of interest in the DED pathosystem, as it should lead to the formal identification of genes modulating parasitic fitness. (sisef.it)
  • Emerging information on vector genomes indicates the presence of genes with similarity to those important for rhabdovirus uptake into cells, and the innate immune system of mammals. (caister.com)
  • By spelling out protein-coding genes in the genome and comparing the house fly sequence to that of the fruit fly, Drosophila melanogaster , the team has endeavored to unravel genetic factors coinciding with house fly features. (genomeweb.com)
  • For example, the M. domestica genome housed almost 150 cytochrome P450 enzyme-coding genes, consistent with a potentially bolstered detoxification system in the house fly. (genomeweb.com)
  • Using these DNA and RNA sequences, the team put together - and annotated - a 691 million base assembly that spans more than three-quarters of the fly's complete genome sequence and contains an estimated 14,810 protein-coding genes. (genomeweb.com)
  • The house fly genome contained sequences for some 771 apparent immune-related genes, for example, including 355 that are not homologous to Drosophila immune genes. (genomeweb.com)
  • Consistent with their role as scent-based waste scavengers, the house flies had higher-than-usual representation by chemoreceptor and odorant-related genes in their genome, authors of the study noted. (genomeweb.com)
  • The deepest branching species in the genus, Y. ruckeri , causative agent of red mouth disease in fish, has the smallest genome (3.7 Mb), although it shares the same core set of approximately 2,500 genes as the other members of the species, whose genomes range in size from 4.3 to 4.8 Mb. (biomedcentral.com)
  • Genome to genome variation in islands with genes encoding functions such as ureases, hydrogeneases and B-12 cofactor metabolite reactions may reflect adaptations to colonizing specific host habitats. (biomedcentral.com)
  • It's a small pilot project and I don't need to map against the whole genome (currently in the form of supercontigs), just my fasta file of 28 genes. (usegalaxy.org)
  • The pan-genome incorporates a large number of genes encoding proteins that may enable P. ananatis to colonize, persist in and potentially cause disease symptoms in a wide range of plant and animal hosts. (biomedcentral.com)
  • Their long-term goal is to use Cas9-expressing mosquitoes together with another technology - called gene drives - to insert and spread genes that suppress the insects while avoiding the resistance that evolution would typically favor. (universityofcalifornia.edu)
  • Previous efforts to use genome editing to prevent mosquitoes from spreading pathogens have been hampered by low mutation rates, poor survival of edited mosquitoes, and inefficient transmission of disrupted genes to offspring. (universityofcalifornia.edu)
  • Gene drives can be used to bias genetic inheritance in favor of rapidly spreading, self-destructive genes - such as those that disrupt fertility - and could be an environmentally friendly and cost-effective way to suppress populations of disease-spreading insects. (universityofcalifornia.edu)
  • PiggyBac is the most promising transposon-based vector system for achieving site-specific targeting of therapeutic genes due to the flexibility of its transposase for being molecularly engineered. (biomedcentral.com)
  • To date, most gene therapy trials have utilized viral vectors for permanent gene transfer due to their high transduction rate and their ability to integrate therapeutic genes into host genomes for stable expression. (biomedcentral.com)
  • Broad Genomics Platform sequences a whole human genome every four minutes. (broadinstitute.org)
  • In 2013, the genome sequences of O. ulmi and O. novo-ulmi were publicly released. (sisef.it)
  • Complete Genome Sequences of Five Foot-and-Mouth Disease Viruses of Serotype A Isolated from Cattle in Nigeria between 2013 and 2015. (sciensano.be)
  • The pan-genome of the eight compared P. ananatis strains consisted of a core genome comprised of 3,876 protein coding sequences (CDSs) and a sizeable accessory genome consisting of 1,690 CDSs. (biomedcentral.com)
  • Next steps should be undertaken to identify the regulatory sequences that can be used to express the guide RNAs from the genome, and once these sequences are identified developing gene drives in the species should be turnkey," Akbari said. (universityofcalifornia.edu)
  • The genome sequences reported here will be used for comparative genomics and to better understand the etiology, relationships and evolution among the spiroplasmas. (biomedcentral.com)
  • Performing genome-wide target profiling on data sets obtained by retrieving chromosomal targeting sequences from individual clones, we have identified several piggyBac and Tol2 hotspots and observed that (4) piggyBac and Tol2 display a clear difference in targeting preferences in the human genome. (biomedcentral.com)
  • DNA transposons are natural genetic elements residing in the genome as repetitive sequences. (biomedcentral.com)
  • We report here genome sequences and comparative analyses of three closely related parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. tongicomis. (lu.se)
  • Scientists in the Broad community are sequencing and analyzing the genomes of a wide range of insects and microorganisms to understand their genetic regulation, population variation, and specialized genomic mechanisms. (broadinstitute.org)
  • The Parasite and Vector Genomics group applies genomic and transcriptomic sequencing data to profile variation among individuals and divergence among species to understand the basic biology underlying vector-borne disease transmission, with a focus on malaria. (broadinstitute.org)
  • Via collaborations with academic and industry partners, we explore the evolutionary basis of drug and insecticide resistance, develop new methods of generating and applying genomic data in parasite and vector systems, and identify the genetic determinants of vaccine efficacy. (broadinstitute.org)
  • Anopheles gambiae s.l. are important malaria vectors, but little is known about their genomic variation in the wild. (kemri-wellcome.org)
  • Whole genome re-sequencing provides powerful data for population genomic studies, allowing robust inferences of population structure, gene flow and evolutionary history. (biomedcentral.com)
  • The small genomes of the DED fungi also facilitate genomic analyses. (sisef.it)
  • After replication, the dsRNA genome is synthesized from genomic ssRNA. (wikimili.com)
  • As they reported online today in Genome Biology , the researchers pooled genomic DNA from half a dozen female house flies, using it as a template to generate sequence reads that were then assembled into a 691 million base M. domestica genome. (genomeweb.com)
  • Over the course of his 30-plus-year career, George Church has pioneered not one, but several transformative fields in medicine, including genomic sequencing, synthetic biology, and, most recently, genome engineering. (medscape.com)
  • Microorganisms (including fungi, bacteria, and viruses) and insect vectors are both key model systems for genomics and important organisms for clinical medicine. (broadinstitute.org)
  • Viruses with segmented RNA genomes can produce at least one protein per segment, sometimes more. (virology.ws)
  • However: why are there perfectly good and successful (-) sense viruses with single-component genomes, like rabies and mumps, then? (virology.ws)
  • In my view, all viruses should have plus strand RNA genomes! (virology.ws)
  • The occurrence and distribution of the economically important viruses and associated insect vectors is however not known for Rwanda and Burundi, where potato is an important food security and income crop. (cipotato.org)
  • We surveyed 194 potato fields for viruses and insect vectors. (cipotato.org)
  • Beyond their reputation as pests, house flies are known to act as a vector for transmitting parasitic bacteria, protozoa, viruses, and worms that cause a range of diseases in humans, livestock, and other animals, the researchers explained. (genomeweb.com)
  • The genome sequence analyses of these viruses revealed that both the eastern and western topotypes as well as their reassortant strains are present in India. (elis.sk)
  • It is not part of the International Committee on Taxonomy of Viruses classification of viruses (ie, it is not a species, genus, or family), which is based on the nature and structure of the viral genome. (msdmanuals.com)
  • Virtually everyone on earth is at risk of becoming ill from bacteria, parasites, and viruses transmitted through the bites of common vectors, such as ticks, mosquitoes, and flies. (cdc.gov)
  • Here, we present inter- and intraspecies analysis of genome-wide RADseq data, in three Anopheles gambiae s.l. species collected from East Africa. (kemri-wellcome.org)
  • We analysed the genomes of two lower and one higher termite species and compared them to the genome of the German cockroach, Blattella germanica , as a closely related non-eusocial outgroup. (nature.com)
  • In this study, we undertook extensive genome-wide comparative analyses of twelve species that conform the Pectobacterium genus. (mdpi.com)
  • Comparing the genome of this fascinating species to other organisms can provide insights into evolutionary biology, for example the development of lactation in mammals. (embl.org)
  • The contribution of so many scientists, especially those from African countries where Glossina is a pest species, was key to unlocking the value of the genome annotations," says Dan Lawson from the Kersey team at EMBL-EBI. (embl.org)
  • Angiosperms are attached to a substrate and unable to move freely, but many of the species that rely on biotic vectors have effectively gained mobility by manipulating the behavior of their pollinator - they "borrow" their wings, legs, or abdomens to transfer pollen. (ubc.ca)
  • Barriers to virus acquisition and infection of specific tissues in the insect host in determining vector competence between and among vector species are beginning to be defined. (caister.com)
  • These data show that high levels of deltamethrin resistance in the main malaria vector species, conferred by enzymatic detoxification, are present in the DRC. (biomedcentral.com)
  • Several species of thrips serve as vectors of TSV, including Microcephalothrips abdominali s and Thrips tabaci . (wikimili.com)
  • He co-authored the landmark paper documenting the first genome sequence of a Daphnia species - as well as the second, new and improved genome sequence of Daphnia pulex ( D. pulex ) published earlier this year. (nd.edu)
  • Currently, genome transplantation is still restricted to few species of ruminant pathogenic mycoplasmas belonging or closely related to the so-called Mycoides cluster including Mycoplasma mycoides subsp. (emynet.eu)
  • Combining comparative genomics and synthetic biology, we also aim at extending genome engineering and transplantation to other bacterial species and use them in applied projects such as construction of new vaccine strains for the control of animal mycoplasma disease and the design of bacterial chassis for biotechnological purposes. (emynet.eu)
  • P. ananatis has an 'open' pan-genome typical of bacterial species that colonize several different environments. (biomedcentral.com)
  • All members are intracellular endosymbionts of invertebrates, and it has been estimated that as many as 15-70% of all insect species on earth are infected by Wolbachia . (uu.se)
  • I am currently involved in several genome sequencing projects of Wolbachia strains infecting different Drosophila species with the aim of determining the evolutionary mechanisms involved inshaping their genomes and determining the genetic factors in phenotypic expression. (uu.se)
  • In order to do so, many insect species have developed very tight symbiotic relationships with microorganisms such as bacteria and fungi that provide them with the nutrients that are lacking in their diet. (uu.se)
  • This method allows us to go out and sample the endosymbiotic diversity from many different insect species and from rare or dissected material. (uu.se)
  • Arbovirus (arthropod-borne virus) is defined as any virus that is transmitted to humans and/or other vertebrates by certain species of blood-feeding arthropods, mostly insects (flies and mosquitoes) and arachnids (ticks). (msdmanuals.com)
  • While the most competent mosquito species for dengue virus transmission is believed to be Aedes aegypti , Aedes albopictus is also a competent vector present in much of Japan during the warmer months. (who.int)
  • In a ten-year collaborative effort, an international team of scientists has published the genome of the tsetse fly Glossina morsitans, a pest native to sub-Saharan Africa that transmits parasitic infections such as sleeping sickness to humans and animals. (embl.org)
  • This research, which also includes targeted CRISPR-Cas9 genome editing, aims to identify the neurobiology behind why the mosquitoes choose their hosts and how to repel them, discoveries that would help protect humans from these often deadly diseases. (nasonline.org)
  • Infected insects take blood meals from humans and their domestic animals and deposit parasite-laden feces. (medscape.com)
  • Akbari and colleagues developed transgenic mosquitoes that stably express a bacterial Cas9 enzyme in the germline, enabling highly efficient genome editing using the CRISPR system. (universityofcalifornia.edu)
  • We know that these ticks as well as other types of insect vectors (such as mosquitoes) can harbor multiple different pathogens. (cdc.gov)
  • Many pathogens rely on their insect vectors for transmission. (elifesciences.org)
  • Such pathogens are under selection to improve vector competence for their transmission by employing various tissue or cellular responses of vectors. (elifesciences.org)
  • However, whether pathogens can actively cause hypoxia in vectors and exploit hypoxia responses to promote their vector competence is still unknown. (elifesciences.org)
  • This valuable work explores how pathogens can cause hypoxia in insect vectors and how responses to hypoxia can be exploited to promote vector competence. (elifesciences.org)
  • Various parasites, bacteria and other disease-causing pathogens are transmitted by insects. (elifesciences.org)
  • Pine wood nematodes, as well as other pathogens, can exploit the biological processes of the insects carrying them to make the insects transmit them more effectively. (elifesciences.org)
  • Dr Kathie Grant is an internationally recognised expert in the field of foodborne pathogens with 30 years experience in clinical and public health microbiology and a research interest in exploiting whole genome sequencing (WGS) of bacterial pathogens to improve the understanding and control of foodborne bacterial illness. (nottingham.ac.uk)
  • NEW YORK (GenomeWeb) - A Cornell University-led team has sequenced and started analyzing the genome of the domestic house fly, Musca domestica , in the hopes of detecting genetic clues for dealing with the pest and pathogens it carries. (genomeweb.com)
  • [ 1 ] T cruzi mostly is found in blood-sucking triatomine insects (kissing bugs) and small mammals in a sylvatic cycle that is enzootic from the southern and southwestern United States to central Argentina and Chile. (medscape.com)
  • These Gateway-adapted ORFs are ideal for easily moving gene content into compatible destination vectors for various proteomics studies. (horizondiscovery.com)
  • These clones are derived from fully-sequenced Mammalian Gene Collection (MGC) full-length cDNAs and subsequently cloned into a Gateway recombinational entry vector. (horizondiscovery.com)
  • Until recently, however, functional analysis of the DED fungi was hampered by the lack of protocols for efficient gene knockout and by the unavailability of a full genome sequence. (sisef.it)
  • Ewan led the analysis of the Human Genome gene set, mouse and chicken genomes and the ENCODE project, focusing on non-coding elements of the human genome. (nottingham.ac.uk)
  • DNA transposons have emerged as indispensible tools for manipulating vertebrate genomes with applications ranging from insertional mutagenesis and transgenesis to gene therapy. (biomedcentral.com)
  • A simple transposon is organized by terminal repeat domains (TRDs) embracing a gene encoding a catalytic protein, transposase, required for its relocation in the genome through a "cut-and-paste" mechanism. (biomedcentral.com)
  • Besides proteins, RNAs can interact with virus genomes to impact replication. (bvsalud.org)
  • Host RNAs tend to bind to single-stranded regions along the virus genomes according to hybridization energetics. (bvsalud.org)
  • The Juicebox Assembly Tools module facilitates de novo assembly of mammalian genomes with chromosome-length scaffolds for under $1000. (dnazoo.org)
  • The non-overlapping targeting preference of piggyBac and Tol2 makes them complementary research tools for manipulating mammalian genomes. (biomedcentral.com)
  • Minute infectious agents whose genomes are composed of DNA or RNA, but not both. (bvsalud.org)
  • I think beside the benefit of genetic reassortment, having a segmented genome in influenza would probably mean all 8 segments can be made into proteins at the same time, shortening replication time. (virology.ws)
  • For the major malaria vector in Africa, Anopheles gambiae , other genetic aspects such as selection and adaptation are also important. (biomedcentral.com)
  • Molecular and omic approaches, however, represent technological advances that should allow rapid developments in the genetic analysis of elms and bark beetle vectors of the disease. (sisef.it)
  • The house fly genome provides a rich resource for enabling work on innovative methods of insect control, for understanding the mechanisms of insecticide resistance, and genetic adaptation to high pathogen loads, and for exploring the basic biology of this important pest," corresponding author Jeffrey Scott, an entomology researcher at Cornell University, and his colleagues wrote. (genomeweb.com)
  • We also adapted several genetic tools for the efficient engineering of mycoplasma genomes cloned in yeast, including a CRISPR/Cas9 system. (emynet.eu)
  • My main interests are in finding out how these tight associations affect genome evolution, determining genetic factors involved in host interactions and exploring the diversity of symbiotic bacteria in nature. (uu.se)
  • Parasitoids are important regulators of arthropod populations, including major agricultural pests and disease vectors, and Nasonia is an emerging genetic model, particularly for evolutionary and developmental genetics. (lu.se)
  • Newly developed genome resources advance Nasonia for genetic. (lu.se)
  • Newly developed genome resources advance Nasonia for genetic research, accelerate mapping and cloning of quantitative trait loci, and will ultimately provide tools and knowledge for further increasing the utility of parasitoids as pest insect-control agents. (lu.se)
  • The recent development of second generation sequencing platforms (reviewed by Mardis [ 7 , 8 ] and Shendure [ 7 , 8 ]) offers an opportunity to change the direction of microbial genomics, enabling the rapid genome sequencing of large numbers of strains of both pathogenic and non-pathogenic strains. (biomedcentral.com)
  • I mostly use genome sequencing and comparative genomics to try to answer these questions. (uu.se)
  • They feed exclusively on the blood of animals, and live comfortably with three different symbiotic bacteria including Wolbachia , which modulates insect reproduction. (embl.org)
  • The overall objective of the team is to generate fundamental knowledge on the genomes and membranes of mollicutes and the molecular mechanisms that govern the interactions of these "minimal" bacteria with their eukaryotic hosts. (emynet.eu)
  • It is one of our main focus to make genome-scale engineering methods available to many mollicutes and other bacteria. (emynet.eu)
  • Comparison of the translated CDSs on the P. ananatis pan-genome with the proteins encoded on all sequenced bacterial genomes currently available revealed that P. ananatis carries a number of CDSs with orthologs restricted to bacteria associated with distinct hosts, namely plant - , animal - and insect - associated bacteria. (biomedcentral.com)
  • Apart from these nutritional interactions, many insects carry additional symbiotic bacteria of which we currently know quite little, but that in some insects have been shown to provide adaptation for specific conditions. (uu.se)
  • Additionally, bidirectional CI can occur if the male and female are infected with different Wolbachia strains and has been implicated as a cause of host speciation and is also being exploited as a method for biocontrol of insect disease vectors. (uu.se)
  • The Medaka fish ( Orizyas latipes ) Tol2 , belonging to the hAT family of transposons, is the first known naturally occurring active DNA transposon discovered in vertebrate genomes [ 10 ]. (biomedcentral.com)
  • Dichlorodiphenyltrichloroethane (DDT) is highly effective against many malaria vector populations and is relatively cost effective, however due to safety concerns, it is allowed for use in IRS programmes only. (biomedcentral.com)
  • She took this chemoreception research in new directions with her lab's studies of the non-model mosquito, Aedes aegypti, a known vector for yellow fever, dengue, and Zika virus. (nasonline.org)
  • De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds. (dnazoo.org)
  • The Center for Cancer Systems Biology of the Dana-Farber Institute created a collection of human open reading frames (ORFs) cloned into a Gateway-entry vector, known as the CCSB Human ORFeome Collection. (horizondiscovery.com)
  • This was possible in the lab because the molecular biology of replication is well characterised and that measles virus is polyploid allowing the engineering of a tri-segmented genome that can replicate and be packaged into virions. (virology.ws)
  • Over 140 insect disease vector biology scientists - half of whom work in African research institutes - examined and manually curated the annotations, bringing to bear their specialist knowledge in all aspects of tsetse fly biology, from sense of smell to reproduction and immunity. (embl.org)
  • Our hope is that this resource will facilitate functional research and be an on-going contribution to the vector biology community. (embl.org)
  • In her early work, Vosshall's molecular biology studies of the model insect Drosophila resulted in several important discoveries. (nasonline.org)
  • This fundamental research is tightly connected with more field-oriented aspects including the integrated epidemiology of grapevine phytoplasmas and mycoplasma genome engineering towards new vaccines, using cutting-edge synthetic biology technologies. (emynet.eu)
  • Using new approaches of synthetic biology, it is now possible to clone a bacterial genome into yeast, to modify it and to transplant it back to a recipient cell. (emynet.eu)
  • Published Nov. 14 in the Proceedings of the National Academy of Sciences (PNAS), the study was led by Omar Akbari , an assistant professor of entomology in UC Riverside's College of Natural and Agricultural Sciences and a member of the university's Institute for Integrative Genome Biology. (universityofcalifornia.edu)
  • You have done so many different things over the course of your career-everything from sequencing the genome and involvement in many companies related to that, to synthetic biology. (medscape.com)
  • Persons with dengue flaviviruses in their blood can transmit the flaviviruses to the mosquito (the vector) 1 day before the onset of the febrile period. (medscape.com)
  • The life span of A aegypti , the primary vector of dengue in the Americas, is usually 21 days. (medscape.com)
  • In the past decade, we have seen not only an increase in the number of dangerous vector-borne diseases, such as dengue and Lyme disease, but also the geographic spread of the vectors. (cdc.gov)
  • Whole genome sequencing by CDC's Dengue Branch later revealed that closely related DENV-3 strains not known to be circulating in the patient's travel region were identified in both patient A and pool A, suggesting local DENV transmission. (medscape.com)
  • I have a workflow where we go from collecting single insects to genome sequencing of their bacterial symbionts, using simple lab methods and whole genome amplification. (uu.se)
  • The whole genome sequence of five strains of S. citri are described herein. (biomedcentral.com)
  • Our study suggests a crucial role of hypoxia-induced developmental responses in shaping vector tolerance to the pathogen and provides clues for potential molecular targets to control pathogen dissemination. (elifesciences.org)
  • However, stable manipulation of DENV genomes is a major molecular challenge, especially when using conventional cloning systems. (bvsalud.org)
  • Widespread drug resistance in Plasmodium parasites and insecticide resistance in the vectors exacerbate the problem [ 3 ]. (biomedcentral.com)
  • Vector control: Agents of selection on malaria parasites? (ed.ac.uk)
  • As with other parasites that infect both mammalian and insect hosts, the life cycle of T cruzi is complex (see image below). (medscape.com)
  • It also recognized that eradication of the tsetse fly vector was the only effective, long-term solution in fighting the disease. (who.int)
  • We show evolutionary signatures of termite eusociality by comparing the genomes and transcriptomes of three termites and the cockroach against the background of 16 other eusocial and non-eusocial insects. (nature.com)
  • What evolutionary advantage is conferred by having a segmented genome? (virology.ws)
  • Why do totiviruses have single-component dsRNA genomes when reoviruses need 10-12 components? (virology.ws)
  • I see +ssRNA, -ssRNA and dsRNA genomes as all part of the same process of RNA replication, just depends which has evolved to be put in the virion. (virology.ws)
  • Having a segmented genome is another way to get around the limitation that eukaryotic mRNAs can only encode one protein. (virology.ws)
  • We discuss our current knowledge of virus acquisition by, replication and movement in, and transmission by their vectors. (caister.com)
  • All these factors are relevant in the Democratic Republic of the Congo (DRC) which is characterized by high transmission (i.e. more than 1 case per 1000 population per year) of Plasmodium falciparum by the highly efficient vectors, Anopheles funestus , Anopheles gambiae and Anopheles coluzzii [ 3 , 4 ]. (biomedcentral.com)
  • Arbovirus is a descriptive term based on transmission by vectors with particular characteristics. (msdmanuals.com)
  • Using AMD, we are monitoring changes in virus genomes, improving our understanding of virus transmission, and increasing our ability to predict future outbreaks. (cdc.gov)
  • This mechanism of transmission contrasts with that of the two subspecies of African trypanosomes that cause human disease, Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense , which are transmitted via the saliva of their vectors, and with the mechanism by which a nonpathogenic trypanosome found in the Americas, Trypanosoma rangeli , is transmitted to its mammalian hosts. (medscape.com)
  • T cruzi can also be transmitted when mammalian hosts ingest infected insects, and this mechanism of transmission may play a major role in maintaining the sylvatic cycle. (medscape.com)
  • Baculoviral expression systems are widely used to produce large quantities of recombinant proteins in insect host cells. (scientifix.com.au)
  • The posttranslational processing and folding of recombinant proteins produced in insect cells more closely resembles that of proteins expressed in mammalian than bacterial cells, so these proteins are more likely to have biological activities and immunological reactivities comparable to proteins that naturally exist in mammalian cells. (scientifix.com.au)
  • Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection. (dnazoo.org)
  • In many crops, genome engineering techniques have enabled researchers and breeders to take advantage of a vast knowledge base of plant physiology, pathology, and genetics. (frontiersin.org)
  • DNA from cultures were sequenced and genome assembled to expand the database to improve detection assays and better understand its genetics and evolution. (biomedcentral.com)
  • By analysing the pan-genome of eight sequenced P. ananatis strains isolated from different sources we identified factors potentially underlying its ability to colonize and interact with hosts in both the plant and animal Kingdoms. (biomedcentral.com)
  • The best management practices are to maintain good sanitation, purchase certified seed, control insects that serve as vectors, and provide barrier crops. (wikimili.com)
  • The virus may be transmitted by thrips vector, mechanical damage, pollen or dodder. (wikimili.com)
  • On the downside, offspring inherit their parent's exact genome, including any mutations that are present. (ubc.ca)
  • She identified the insect odorant receptors and showed that they function as odor-gated ion channels. (nasonline.org)
  • We are involved in several international projects aiming at producing new vaccines against severe animal diseases such as Contagious Bovine Pleuropneumonia and Contagious Caprine Pleuropneumonia ( https://www.idrc.ca/en/article/engineering-wild-fast-growing-mycoplasma-bacterium-generate-novel-vaccine-contagious-caprine ). (emynet.eu)
  • The cereal-infecting cytorhabdoviruses and nucleorhabdoviruses are transmitted to new plant hosts in a persistent, propagative manner by their leafhopper (Cicadellidae and planthopper (Fulgoroidea) vectors. (caister.com)
  • Our study shows that the parasite genome evolves very fast under laboratory conditions. (crg.eu)
  • Epimastigotes are an extracellular and noninfective form of the parasite found in the midgut of insect vectors, where they multiply by binary fission. (medscape.com)
  • The trypomastigote is the infective flagellated form of the parasite found in the blood of the mammalian hosts (blood trypomastigote) and in the hindgut of vectors (metacyclic trypomastigote). (medscape.com)
  • The epimastigote form of Trypanosoma cruzi is the multiplying stage of the parasite that grows in the gut of the insect vector and also in cell-free culture medium as shown here. (medscape.com)
  • A genome-scale library of Gateway-adapted human ORF clones, the CCSB Human ORFeome Library (aka hORFeome V5.1) is ideal for transferring thousands of open reading frames into a variety of protein expression systems. (horizondiscovery.com)
  • In 2015, he joined the National Human Genome Research Institute as a founding member of the Genome Informatics Section. (nottingham.ac.uk)
  • The argasid tick Ornithodoros erraticus is the main vector of tick-borne human relapsing fever (TBRF) and African swine fever (ASF) in the Mediterranean Basin. (biomedcentral.com)
  • Vosshall has made vital contributions to our understanding of insect olfactory systems, with important implications for protecting human health. (nasonline.org)
  • Tol2 is a standard tool for manipulating zebrafish genomes and has been demonstrated to transpose effectively in frog, chicken, mouse and human cells as well [ 11 ]. (biomedcentral.com)
  • Early in infection when symptoms are few yet treatment has the greatest chance of success, patients are usually unaware of their infection, which remains undetected, especially as health services are usually poorly staffed and equipped or non-existent in the remote rural areas where human contact with the vector is greatest. (who.int)
  • Human genome research and society : proceedings of the Second International Bioethics Seminar in Fukui, 20-21 March, 1992 / editors, Norio Fujiki & Darryl R. J. Macer. (who.int)
  • TSV purified from infected plants consists of a ss-RNA genome encapsulated by spheroid particles made up of coat protein subunits. (wikimili.com)
  • [4] Once the virus becomes systemic, it can be transmitted by vectors. (wikimili.com)
  • Upon entry of a virus into a host cell, the environment of that cell promotes the disassembly of the virus leading to the release of its genome RNA. (purdue.edu)
  • In the Mediterranean Basin, this tick is the main vector of the African swine fever (ASF) virus and of several Borrelia spp. (biomedcentral.com)
  • If you use this genome assembly in your research, please check that the conditions of use associated with the draft permit it, and acknowledge the following work. (dnazoo.org)