Wakefulness-Promoting AgentsReceptors, Adrenergic, alpha-2VasodilationInterleukin 1 Receptor Antagonist ProteinNeurokinin-1 Receptor AntagonistsDose-Response Relationship, DrugPurinergic P1 Receptor AntagonistsRats, Sprague-DawleyPiperidinesHistamine H2 AntagonistsSerotonin 5-HT3 Receptor AntagonistsExcitatory Amino Acid AntagonistsAngiotensin Receptor AntagonistsDopamine AntagonistsAdenosine A2 Receptor AntagonistsSerotonin 5-HT2 Receptor AntagonistsHormone AntagonistsRats, WistarAdenosine A1 Receptor AntagonistsPurinergic P2 Receptor AntagonistsReceptors, EndothelinNarcotic AntagonistsHistamine H1 AntagonistsMuscarinic AntagonistsGABA-A Receptor AntagonistsAdrenergic alpha-1 Receptor AntagonistsSerotonin AntagonistsHistamine AntagonistsReceptors, Adrenergic, alphaGABA AntagonistsSialoglycoproteinsReceptor, Endothelin AVasodilator Agentsalpha 1-AntitrypsinReceptors, SerotoninLeukotriene AntagonistsAdrenergic alpha-AntagonistsNicotinic AntagonistsReceptors, N-Methyl-D-AspartateSerotonin 5-HT1 Receptor AntagonistsNitric OxideDizocilpine MaleateAcetylcholineReceptors, Interleukin-1Biphenyl CompoundsAdrenergic alpha-2 Receptor AntagonistsTetrazolesAdenosineEndothelium, VascularPyridinesBenzazepinesRadioligand AssayBlood PressureBradykininXanthinesDrug InteractionsEndothelin-1Peptides, CyclicGuinea PigsTime FactorsVasoconstrictionPyrazolesIndolesSulfonamidesQuinoxalinesCells, CulturedSerotonin Receptor AgonistsReceptors, BradykininSubstance PHistamine H3 AntagonistsEnzyme InhibitorsBinding, CompetitiveRegional Blood FlowAzepinesLosartanSignal TransductionAdrenergic AntagonistsSerotoninHypoxia-Inducible Factor 1, alpha SubunitReceptor, Endothelin Balpha7 Nicotinic Acetylcholine ReceptorPiperazinesForearmReceptors, ThromboxaneElectric StimulationGABA-B Receptor AntagonistsNeuronsArteriolesDisease Models, AnimalCimetidineReceptors, Neurokinin-1Adenosine A3 Receptor AntagonistsPurinergic P2X Receptor AntagonistsMice, Inbred C57BLPrazosinBehavior, AnimalReceptors, VasopressinPyrrolidinesReceptors, Adrenergic, alpha-1Interleukin-1