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  • gastric
  • With respect to the digestive system , VIP seems to induce smooth muscle relaxation ( lower esophageal sphincter , stomach, gallbladder), stimulate secretion of water into pancreatic juice and bile , and cause inhibition of gastric acid secretion and absorption from the intestinal lumen. (wikipedia.org)
  • Gastric sodium loading results in an increase in the portal venous concentration of vasoactive intestinal peptide (VIP) and down-regulation of both the intrahepatic and circulating renin-angiotensin systems. (clinsci.org)
  • K cells secrete gastric inhibitory peptide, an incretin, which also promotes triglyceride storage. (wikipedia.org)
  • porcine
  • Galanin was first identified from porcine intestinal extracts in 1978 by Professor Viktor Mutt and colleagues at the Karolinska Institute, Sweden using a chemical assay technique that detects peptides according to its C-terminal alanine amide structure. (wikipedia.org)
  • gastrin releasi
  • The vagus nerve (CN X) also releases gastrin releasing peptide onto G cells. (wikipedia.org)
  • The G cells secrete gastrin, post-ganglionic fibers of the vagus nerve can release gastrin-releasing peptide during parasympathetic stimulation to stimulate secretion. (wikipedia.org)
  • 2002
  • Comparison of an 18 F labeled deravative of vasoactive intestinal peptide and 2-deoxy-2-[ 18 F)fluoro-D-glucose in nude mice bearing breast cancer xenografts," Molecular Imaging and Biology , vol. 4, no. 5, pp. 369-379, 2002. (hindawi.com)
  • vitro
  • Vasoactive intestinal peptide (VIP) has been shown to enhance steroid production in vivo in rabbits (1) and humans (2) and in vitro in prepubertal rat ovaries (3), isolated rat granulosa cells (4), as well as cultured baboon granulosa cells (5). (springer.com)
  • stomach
  • Irrespective of the cause, achlorhydria can result as known complications of bacterial overgrowth and intestinal metaplasia and symptoms are often consistent with those diseases: gastroesophageal reflux disease (source needed) abdominal discomfort early satiety weight loss diarrhea constipation abdominal bloating anemia stomach infection malabsorption of food. (wikipedia.org)
  • Acidic environment of stomach helps conversion of pepsinogen into pepsin which is most important to digest the protein into smaller component like complex protein into simple peptides and amino acids inside stomach which is later absorbs by gastro intestinal tract. (wikipedia.org)
  • regulatory
  • This demonstrates that it is essential to study the effects of galanin and other regulatory peptides in their autologous species. (wikipedia.org)
  • role
  • The discrete pattern of hybridization for VIP/PHI mRNA indicates that these two peptides are synthetized in rat retina and SCN and suggests that they may play a key role in the photic entrainment to the SCN regulating various circadian rhythms. (springer.com)
  • receptor
  • Vasoactive intestinal polypeptide receptor 1 also known as VPAC1, is a protein, that in humans is encoded by the VIPR1 gene. (wikipedia.org)
  • Immunohistochemically, prostatic small cell carcinoma are positive for thyroid transcription factor 1 (TTF-1), CD56, chromogranin A, synaptophysin, neuron-specific enolase, calcitonin and bombesin/gastrin-releasing peptide, while lacking, or rarely and weakly expressing, androgen receptor and prostate-specific antigen. (wikipedia.org)
  • Octreotide can also be labelled with a variety of radionuclides, such as yttrium-90 or lutetium-177, to enable peptide receptor radionuclide therapy (PRRT) for the treatment of unresectable neuroendocrine tumours. (wikipedia.org)
  • amyloid
  • Several factors, including glutamate itself, biogenic amines, arachidonic acid, and amyloid β-peptide, were found to rapidly affect glutamate uptake by post-translational modification of glial glutamate transporters (for review, see Gegelashvili and Schousboe, 1998 ). (jneurosci.org)
  • This 42-amino acid peptide is the predominant form of amyloid beta-protein in the brains of Alzheimer patients. (severnbiotech.com)
  • form
  • The binding characteristics of a monoiodinated form of vasoactive intestinal peptide (M-[125I]VIP) to the membranes of astrocytes, intraparenchymal microvessels and synaptosomes were analyzed in mouse cerebral cortex. (epfl.ch)