Filter...

AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care

Select a category...

VasculitisPolyarteritis NodosaSystemic VasculitisChurg-Strauss SyndromeAnti-Neutrophil Cytoplasmic Antibody-Associated VasculitisWegener GranulomatosisCentral Nervous SystemAntibodies, Antineutrophil CytoplasmicVasculitis, Central Nervous SystemVasculitis, Leukocytoclastic, CutaneousMicroscopic PolyangiitisRetinal VasculitisCentral Nervous System DiseasesPurpura, Schoenlein-HenochMyeloblastinCentral Nervous System NeoplasmsErythrovirusUrogenital NeoplasmsNervous SystemTakayasu ArteritisPlasma ExchangeMucocutaneous Lymph Node SyndromeBrainImmunosuppressive AgentsCentral Nervous System InfectionsPeroxidaseSkin Diseases, VascularPeripheral Nervous SystemImmunoglobulins, IntravenousGlomerulonephritisAutoimmune DiseasesAutoantibodiesRheumatoid VasculitisCentral Nervous System Viral DiseasesCyclophosphamideNeuronsAdrenal Cortex HormonesSerine EndopeptidasesNecrosisCentral Nervous System AgentsCryoglobulinemiaSpinal CordNeutrophilsGlucocorticoidsCentral Nervous System Fungal InfectionsEnteric Nervous SystemAutoantigensNervous System DiseasesBiological MarkersRetrospective StudiesNervous System Physiological PhenomenaAutonomic Nervous SystemTreatment OutcomeNeurogliaEnzyme-Linked Immunosorbent AssayKidney DiseasesCentral Nervous System Bacterial InfectionsSympathetic Nervous SystemMyelin SheathArteritisBlood-Brain BarrierAstrocytesBrain DiseasesTuberculosis, Central Nervous SystemNervous System NeoplasmsBehcet SyndromeNerve Tissue ProteinsImmunohistochemistryDemyelinating DiseasesEncephalomyelitis, Autoimmune, ExperimentalAxonsOligodendrogliaMice, Inbred C57BLMolecular Sequence DataCerebrospinal FluidDisease Models, AnimalGene Expression Regulation, DevelopmentalIn Situ HybridizationPeripheral Nervous System DiseasesLupus Vasculitis, Central Nervous SystemCryoglobulinsMultiple SclerosisEncephalitisBrain NeoplasmsMeningoencephalitisGiant Cell ArteritisEncephalomyelitisTime FactorsMicrogliaCells, CulturedPurpuraPeripheral NervesFatal OutcomeEncephalitis, ViralAmino Acid SequenceMeningesRNA, MessengerBrain ChemistryMagnetic Resonance ImagingMice, Knockout

Granulomatosis with polyangiitisLeukocytoclasticLarge vessel vasculitisCNSVInflammation of bloodPrimaryCutaneousSecondaryDiseasesInfectionVessel wallHistologicPolyarteritis nodosaTissuesKawasakiOrgansClassificationVeinsAdultsGranulomatousClinicalFormsImmuneSmallChildrenBloodAffectRareTreatment

Granulomatosis with polyangiitis4

• Churg-Strauss Syndrome (CSS), now also referred to by its medically more accurate term eosinophilic granulomatosis with polyangiitis (EGPA), is a rare systemic vasculitis (inflammation in the wall of blood vessels of the body), predominantly affecting small-sized vessels. (vasculitisfoundation.org)
• Because antineutrophil cytoplasmic auto-antibodies (ANCA) can be detected in the serum (liquid and a cellular part of the blood) in up to 40% of the patients, it is also considered one of the three ANCA-associated vasculitides, along with granulomatosis with polyangiitis (Wegener's) and microscopic polyangiitis. (vasculitisfoundation.org)
• Other possible secondary causes of cerebral vasculitis are infections, systemic auto-immune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis, medications and drugs (amphetamine, cocaine and heroin), some forms of cancer (lymphomas, leukemia and lung cancer) and other forms of systemic vasculitis such as granulomatosis with polyangiitis, polyarteritis nodosa or Behçet's disease. (wikipedia.org)
• Granulomatosis with Polyangiitis (GPA) Granulomatosis with polyangiitis is characterized by necrotizing granulomatous inflammation, small- and medium-sized vessel vasculitis, and focal necrotizing glomerulonephritis, often with crescent. (merckmanuals.com)

Leukocytoclastic2

• Leukocytoclastic vasculitis is a histopathologic term used to describe findings in small-vessel vasculitis. (merckmanuals.com)
• Leukocytoclastic vasculitis. (medscape.com)

Large vessel vasculitis3

• The predominantly large vessel vasculitis is Takayasu arteritis. (medscape.com)
• Note that the main large vessel vasculitis that affects children is Takayasu arteritis , and that temporal arteritis is not seen in the pediatric population. (medscape.com)
• Giant cell arteritis (GCA) is a primary large-vessel vasculitis found commonly in older people aged 50 or more years and mainly affects the extracranial branches of the carotid artery. (surgicalneurologyint.com)

CNSV2

• Central nervous system vasculitis (CNSV) is inflammation of blood vessel walls in the brain or spine. (vasculitisfoundation.org)
• We operationally define central nervous system vasculitis (CNSV) as any inflammatory vasculopathy producing nonatheromatous inflammation of intracranial vessels either directly (eg, primary CNS vasculitis) or indirectly via inflammation of CNS parenchyma with secondary vascular involvement (eg, as seen with infections, tumors, and certain autoimmune conditions). (ajnr.org)

Inflammation of blood1

• Vasculitis is defined as inflammation of blood vessels. (medscape.com)

Primary7

• Primary" angiitis/vasculitis of the central nervous system (PACNS) is said to be present if there is no underlying cause. (wikipedia.org)
• The exact mechanism of the primary disease is unknown, but the fundamental mechanism of all vasculitides is autoimmunity. (wikipedia.org)
• This article focuses on the primary systemic vasculitides of childhood. (medscape.com)
• Other subtypes of primary childhood vasculitis are much rarer. (medscape.com)
• Practitioners may find it helpful to think of primary systemic vasculitides based on the predominant size of the involved vessels, as suggested by the Chapel Hill Classification. (medscape.com)
• Primary vasculitis has no known cause. (merckmanuals.com)
• The clinical spectrum of primary renal vasculitis. (medscape.com)

Cutaneous3

• The image below depicts nodules in cutaneous polyarteritis nodosa (PAN), a systemic vasculitis characterized by necrotizing inflammatory lesions that affect medium-sized and small muscular arteries. (medscape.com)
• Cutaneous Vasculitis Cutaneous vasculitis refers to vasculitis affecting small- or medium-sized vessels in the skin and subcutaneous tissue but not the internal organs. (merckmanuals.com)
• Cutaneous vasculitis may be limited to the. (merckmanuals.com)

Secondary2

• Vasculitis can also occur secondary to another disease, and this should be ruled out. (medscape.com)
• Secondary vasculitis may be triggered by an infection, a drug, or a toxin or may occur as part of another inflammatory disorder or cancer. (merckmanuals.com)

Diseases3

• Vasculitis is a family of rare diseases that can affect people of all ages. (vasculitisfoundation.org)
• However, an overlap of vessel sizes affected within the diseases is noted, and the phenotype and pattern of organ involvement in vasculitis seems to be independent of vessel size. (medscape.com)
• Central nervous system vasculitides are elusive diseases that are challenging to diagnose because brain biopsies have high false-negative rates. (ajnr.org)

Infection1

• 14. Central Nervous System Vasculitis due to Infection. (davidsyounger.com)

Vessel wall2

• Cerebral vasculitis (sometimes the word angiitis is used instead of "vasculitis") is vasculitis (inflammation of the blood vessel wall) involving the brain and occasionally the spinal cord. (wikipedia.org)
• Some forms of vasculitis are characterized by giant cells in the vessel wall. (merckmanuals.com)

Histologic1

• See Vasculitis: Case Presentations , a Critical Images slideshow, for more information on clinical, histologic, and radiographic imaging findings in various forms of vasculitis. (medscape.com)

Polyarteritis nodosa1

• For example, Kawasaki disease is characterized by a mucocutaneous syndrome and coronary artery inflammation, whereas polyarteritis nodosa (PAN), another medium-vessel vasculitis, manifests with nodular skin lesions, neuropathy, and hypertension. (medscape.com)

Tissues1

• A result of vasculitis is that the tissues and organs supplied by affected blood vessels do not get enough blood. (vasculitisfoundation.org)

Kawasaki3

• The most common forms of systemic vasculitis in children are Henoch-Schonlein purpura (HSP) and Kawasaki disease (KD). (medscape.com)
• Kawasaki Disease Kawasaki disease is a vasculitis, sometimes involving the coronary arteries, that tends to occur in infants and children between the ages of 1 year and 8 years. (merckmanuals.com)
• The most common forms of systemic vasculitis in children are Henoch-Schoenlein purpura (HSP) and Kawasaki disease (KD). (medscape.com)

Organs1

• the vessel inflammation (true vasculitis) is only part of the pathophysiology and there is predominant parenchymal inflammation in a characteristic pattern that involves specific organs. (merckmanuals.com)

Classification2

• As such, the classification of childhood vasculitides incorporates both vessel size and organ manifestations. (medscape.com)
• As such, the most recent classification of childhood vasculitides incorporates both vessel size and organ manifestations. (medscape.com)

Veins1

• Vasculitis means inflammation of the blood vessels, arteries, veins or capillaries. (vasculitisfoundation.org)

Adults2

• These criteria represent a modification and adaptation of existing American College of Rheumatology and Chapel Hill criteria for vasculitis in adults. (medscape.com)
• 8. Stroke due to Vasculitis in Children and Adults. (davidsyounger.com)

Granulomatous1

• Predominantly small vessel vasculitis is divided into granulomatous and nongranulomatous. (medscape.com)

Clinical2

• However, the clinical characteristics and outcomes of these three vasculitides differ noticeably. (vasculitisfoundation.org)
• Characteristic clinical features are caused by stenotic large vessels and subsequently decreased blood supply to the organ systems. (medscape.com)

Forms1

• Though some forms of vasculitis improve on their own, most require treatment. (vasculitisfoundation.org)

Immune2

• Cryogloblinemia is a vasculitis of small blood vessels that is caused by deposition of immune complexes: large aggregates of antibodies and the other proteins they are bound to. (vasculitisfoundation.org)
• Some other types of vasculitis are also caused by immune complexes, but cryoglobulinemia is defined by a laboratory test that identifies immune complexes that fall out of solution in the cold. (vasculitisfoundation.org)

Small1

• Small-vessel vasculitis. (medscape.com)

Children1

• Henoch-Schönlein Purpura (HSP) is the most common vasculitis in children and is usually a benign disease that completely resolves in most patients without the need for aggressive treatment. (vasculitisfoundation.org)

Blood2

• The different types of vasculitis are classified according to the size and location of the blood vessels that are affected. (vasculitisfoundation.org)
• If blood flow in a vessel with vasculitis is reduced or stopped, the parts of the body that receive blood from that vessel begins to die. (wikipedia.org)

Affect1

• Vasculitis can involve vessels of any size and can affect any organ system. (medscape.com)

Rare1

• Cerebral vasculitis is a very rare condition that is difficult to diagnose, and as a result there are significant variations in the way it is diagnosed and treated. (wikipedia.org)

Treatment1

• 12. Treatment of Vasculitis of the Nervous System. (davidsyounger.com)