• Children with hypertension should also be screened for other risk factors for cardiovascular disease, including diabetes mellitus and hyperlipidemia, and should be evaluated for target organ damage with a retinal examination and echocardiography. (aafp.org)
  • 2 High blood pressure in childhood commonly leads to hypertension in adulthood, 3 and adult hypertension is the leading cause of premature death around the world. (aafp.org)
  • 4 Children with hypertension may have evidence of target organ damage, including left ventricular hypertrophy and pathologic vascular changes. (aafp.org)
  • 5 , 6 Primary hypertension in children is also commonly associated with other risk factors for cardiovascular disease (CVD), such as hyperlipidemia and diabetes mellitus. (aafp.org)
  • 7 , 8 Despite the high prevalence and potential risks of hypertension in children, physicians often do not recognize the condition in this population. (aafp.org)
  • In one study, hypertension was diagnosed in only 26 percent of children with documented high blood pressure in an electronic medical record. (aafp.org)
  • All children with confirmed hypertension and overweight children with prehypertension should be evaluated for additional risk factors for cardiovascular disease, including screening for diabetes mellitus and hyperlipidemia. (aafp.org)
  • Many patients on potent agents addressing modifiable cardiovascular risk factors, such as hypertension, hyperlipidemia or diabetes, still suffer from cardiovascular complications, including acute coronary syndromes (ACS). (frontiersin.org)
  • The caricature of the typical patient with hyperuricemia is an obese middle-aged man with hypertension, diabetes mellitus, and hyperlipidemia who is given to excessive drinking. (natap.org)
  • Part of managing heart failure includes preventing or lowering high blood pressure (hypertension) and high cholesterol (hyperlipidemia), as well as taking all your prescribed medications. (sutterhealth.org)
  • Drug classes used to treat cardiovascular indications such as hyperlipidemia, hypertension are likely to fuel expansion of the global cardiovascular drugs market from 2017 to 2025. (ipsnews.net)
  • Most physicians routinely screen for traditional CVD risk factors, such as hypertension, hyperlipidemia and tobacco use. (cdc.gov)
  • It was believed that age, hyperlipidemia, hypertension, diabetes and smoking are common risk factors for cardiovascular disease. (amedi.sk)
  • Besides hyperlipidemia other risk factors for cardiovascular disease include hypertension, smoking, diabetes, kidney disease, increasing age, strong family history of heart diseases and male gender. (medthical.com)
  • Researchers at the Stroke Research and Prevention Group (HKU Stroke), Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) found that the incidence of 'young stroke' (strokes occurring in individuals aged 18 to 55 years) has increased by 30% in Hong Kong from 2001 to 2021, thus called for better control of vascular risk factors, in particular hypertension. (hku.hk)
  • Among them, 53% had hypertension, 44% had hyperlipidemia, 26% had a smoking history, 19% were obese, and 17% had diabetes (Figure 2). (hku.hk)
  • Among those with hypertension, hyperlipidaemia and diabetes, 33%, 64% and 23% were newly diagnosed during the stroke admission respectively. (hku.hk)
  • Hypertension is the leading modifiable risk factor of stroke and previous studies have shown that with every 20mmHg increase in systolic blood pressure or 10mmHg increase in diastolic blood pressure, there is a 30-50% increased risk of stroke 4 . (hku.hk)
  • Hypertension, hyperlipidaemia and diabetes are often the result of poor lifestyle and dietary practices and measures to control for these vascular risk factors through a better diet with significantly lower sodium intake, regular exercise and smoking cessation is strongly recommended for stroke prevention. (hku.hk)
  • His past history includes mild cognitive impairment ( precursor to Alzheimer’s ), hypertension and high cholesterol ( stroke risk factors) . (neuroems.com)
  • This is indicative of narrowed arteries, fitting in with the history of hyperlipidemia & hypertension. (neuroems.com)
  • Hypertension, or high blood pressure, causes a strain on the heart and can thicken the heart muscle over many years causing heart enlargement and heart failure. (ccatlanta.com)
  • The high rate in Japanese population is attributed to the high frequency of hypertension. (karger.com)
  • Hypogonadism that results in suboptimal testosterone levels is very dangerous as it contributes to higher risk of diabetes, hyperlipidemia, hypertension, vascular plaque, Metabolic Syndrome and myocardial infarction. (hippevo.com)
  • The higher risk remained significant even after adjusting for age, gender and [cardiovascular] risk factors including age, gender, hypertension, smoking history and hyperlipidemia. (nso-korpus.info)
  • Determination of UA as an etiological factor responsible for the pathogenesis of vascular diseases including stroke may also bring the treatment of hyperuricemia such as hyperlipidemia or hypertension, which are routinely treated after stroke. (itmedicalteam.pl)
  • Three metabolic abnormalities were also included in the study: diabetes, hypertension (high blood pressure) and hyperlipidaemia (high cholesterol). (inquirer.net)
  • The most common risk factors for stroke in patients with AF are included in the CHA2DS2-VASc score (congestive heart failure, hypertension, age, diabetes mellitus, previous stroke, vascular disease, gender). (termedia.pl)
  • Metabolic Syndrome (MS) is the denomination proposed by the World Health Organization (WHO) 42 , which designates a set of risk factors for cardiovascular diseases (CVDs), such as visceral obesity, dyslipidemia, high hypertension, glucose intolerance and insulin resistance 32 , which frequently are presented together. (bvsalud.org)
  • Hypertension and hyperlipidemia are more common among workers exposed to loud noise in the workplace, suggests new research from the National Institute for Occupational Safety and Health (NIOSH), part of the Centers for Disease Control and Prevention (CDC). (medscape.com)
  • Background & objective: Diabetes mellitus is one of the most common metabolic disorders that causes micro- and macro-vascular complications. (amrita.edu)
  • Subgroup analyses showed that a relationship between gout and the risk of acute MI was present among nonusers of alcohol, diuretics, or aspirin and among those who did not have metabolic syndrome, diabetes mellitus, or obesity. (natap.org)
  • Patients with diabetes mellitus are at high risk of cardiovascular events because of abnormal lipid levels status. (heraldopenaccess.us)
  • High prevalence of dyslipidemia among type 2 diabetes mellitus in Mukalla city were observed and so the common patterns of dyslipidemia is LDL-C followed by cholesterol. (heraldopenaccess.us)
  • Diabetes Mellitus (DM) is a syndrome consisting of metabolic, vascular and neuropathic components that are interrelated. (heraldopenaccess.us)
  • Diabetes mellitus is a common secondary cause of hyperlipidemia, particularly if glycemic control is poor, which in-turn is an important risk factor for atherosclerosis and coronary heart disease [12,13]. (heraldopenaccess.us)
  • Plasma copeptin and the risk of diabetes mellitus. (lu.se)
  • Libby P. The vascular biology of atherosclerosis. (medlineplus.gov)
  • Peripheral arterial occlusive disease results from the vascular aging, atherosclerosis or thrombosis, when vascular stenosis or occlusion occur and in the end patients are suffered from ischemic disease. (envita.site)
  • BACKGROUND: Atherosclerosis is a deadly consequence of cardiovascular disease and has very high mortality rate worldwide. (bvsalud.org)
  • Natural products from traditional Chinese medicine have shown promising therapeutic potential against atherosclerosis by means of regulating the expression of specific genes, stabilizing arterial plaques and protecting vascular endothelial cells. (bvsalud.org)
  • This study will investigate the effect of Agpat2 on hyperlipidemia and atherosclerosis. (bvsalud.org)
  • CONCLUSIONS: Our results show that Agpat2 deficiency led to more severe hyperlipidemia, liver fibrosis and aggravation of atherosclerosis in Ldlr-/- mice. (bvsalud.org)
  • This study provided additional insights into the role of adipose tissue in hyperlipidemia and atherosclerosis. (bvsalud.org)
  • Vascular toxicity caused by cancer treatment can present as vasospasm, arterial thrombosis, and accelerated atherosclerosis. (bvsalud.org)
  • Hyperhomocysteinemia is associated with significant risk of stroke, narrowing of the carotid artery due to atherosclerosis and peripheral vascular disease. (amedi.sk)
  • Hardening of the arteries, or atherosclerosis, that occurs due to hyperlipidemia compromises blood flow to the aorta and puts you at risk. (njheartandvascularcare.com)
  • National Heart Lung and Blood Institute-R01HL137771, National Institute of Aging-R21AG058983, and National Institute of Alcohol Abuse and Alcoholism-R21AA026922) Animal models of atherosclerosis, vascular aging, and chronic binge drinking have been established, and conditional tissue specific transgenic and knockout mice strains are employed to decipher the in vivo role of thiol redox signaling in vascular dysfunction and development of atherosclerosis. (bu.edu)
  • In addition to understanding the molecular mechanism of atherosclerosis, our research interests also lie in developing multidisciplinary approach to measuring vascular function in murine animals, and to targeted delivery of nanomedicine to cardiovascular system. (bu.edu)
  • High levels of serum triglycerides help mark conditions that are associated with increased risk for CHD and peripheral atherosclerosis. (cdc.gov)
  • Substantially Elevated Atherosclerotic Risks in Japanese Severe Familial Hypercholesterolemia Defined by the International Atherosclerosis Society. (cdc.gov)
  • There is evidence that elevated homocysteine is associated with higher risk of coronary artery disease. (amedi.sk)
  • In one study, the association between OCT angiography (OCTA), microvascular parameters, and risk of subclinical coronary artery disease was assessed in 654 patients with type 2 diabetes who were receiving ophthalmic care. (nso-korpus.info)
  • About 35% had obstructive coronary artery disease and 15% had high-risk coronary artery disease. (nso-korpus.info)
  • The risk of obstructive coronary artery disease and high-risk coronary artery disease was significantly higher among the low vascular density SCP and DCP quartile groups," Yoon said. (nso-korpus.info)
  • ACCELERATE studied evacetrapib in participants with high-risk vascular disease (previous myocardial infarction, stroke or peripheral vascular disease, or several cardiovascular risk factors). (wikipedia.org)
  • In addition, patients are at risk for many other neurologic complications of HIV infection, including vacuolar myelopathy, peripheral neuropathies, and polymyositis, which can contribute to further disability. (medscape.com)
  • To reduce the risk of total mortality by reducing risk of coronary heart disease death, non-fatal myocardial infarction and stroke, and the need for coronary and non-coronary revascularization procedures in adults with established coronary heart disease, cerebrovascular disease, peripheral vascular disease, and/or diabetes, who are at high risk of coronary heart disease events. (nih.gov)
  • Having high levels of cholesterol will narrow the blood vessels with plaque (clot formation ) and increase risk of cardiovascular disease like heart diseases, stroke and peripheral vascular disease. (medthical.com)
  • But when cardiovascular complications come in , he may experience chest pain (heart diseases), leg pain and gangrene ( peripheral vascular disease ), numbness and weakness ( stroke). (medthical.com)
  • They then looked at the patient's records at an average of 5 years and four months later to see who had gone on to develop each of four kinds of CVD events: coronary heart disease (CHD), cerebrovascular disease (in particular strokes), heart failure, or peripheral vascular disease (PVD). (inquirer.net)
  • The heart disease (CHD) and cerbrovascular or term diabetic dyslipidaemia comprises a peripheral vascular disease [ 2,3 ]. (who.int)
  • Causal Association of Cardiovascular Risk Factors and Lifestyle Behaviors With Peripheral Artery Disease: A Mendelian Randomization Approach. (cdc.gov)
  • Development of a polygenic risk score to improve detection of peripheral artery disease. (cdc.gov)
  • State 3 teaching strategies to prevent vascular complications. (slideserve.com)
  • To date, correlations with the presence of this mutation and significantly longer duration of disease, a higher rate of complications (fibrosis, hemorrhage, and thrombosis), and treatment with cytoreductive therapy have only been identified by one group. (ashpublications.org)
  • Glycemic control remains the major clinical objective in management of diabetes whereas long-term management targets in prevention of micro vascular and macro vascular complications. (heraldopenaccess.us)
  • A study of 21,848 non-emergent, high-risk patients who underwent percutaneous coronary intervention (PCI) with percutaneous ventricular assist devices (PVADs), including Impella® heart pumps, demonstrates the PVAD patients had a lower rate of mortality and complications than patients who underwent PCI with intra-aortic balloon pumps (IABPs). (heartrecovery.com)
  • A bulge in the wall of an artery is known as an aneurysm and it puts you at risk of serious complications, including stroke. (njheartandvascularcare.com)
  • Large thoracic aneurysms are at risk of rupture, but small ones may never cause complications. (njheartandvascularcare.com)
  • Discontinue if the following develop jaundice, visual problems associated with retinal vascular lesions (may cause contact lens intolerance), any signs of VTE, migraine with unusual severity, significang blood pressure increase, severe depression, increased risk of thromboembolic complications after surgery. (medscape.com)
  • Patients with severe malaria are at risk for life-threatening complications including: renal failure, acute respiratory distress syndrome (ARDS), severe hemolytic anemia, and cerebral malaria. (cdc.gov)
  • Hyperlipidemia, characterized by the abnormal blood lipid profiles, is one of the dominant factors of many chronic diseases such as diabetes, obesity, and cardiovascular diseases (CVD). (hindawi.com)
  • Apart from CVD, hyperlipidemia is also closely associated with diabetes, insulin resistance, and obesity [ 10 ]. (hindawi.com)
  • 2 Obesity is one of the highest risk factors for the development of T2DM. (nursekey.com)
  • Causes of hyperlipidemia can be due to familial genetic inherited condition, high fat diet, sedentary lifestyle , obesity, diabetes , alcoholism and physiological state like in pregnancy. (medthical.com)
  • 3. Losing weight : Obesity increases bad cholesterol and risk of cardiovascular diseases. (medthical.com)
  • Obesity and a high fat diet poisons the Leydig cells, reducing testosterone levels. (hippevo.com)
  • PD has been suggested as a possible risk factor for some of the components of MS, such as diabetes, obesity and dyslipidemia. (bvsalud.org)
  • The relatively high prevalence of the metabolic syndrome is a worldwide phenomenon that seems to be increasing in parallel with the obesity prevalence 16 . (bvsalud.org)
  • In an elderly population with cognitive impairment, we investigated the association between serum uric acid (sUA) and serum homocysteine (sHcy), known risk factors for cerebrovascular disease. (mdpi.com)
  • The team found that those who were MHO had a 49 percent higher risk of coronary heart disease, seven percent higher risk of cerebrovascular disease and a 96 percent higher risk of heart failure than normal-weight metabolically healthy individuals. (inquirer.net)
  • Importantly, and perhaps surprisingly, the results also showed that those who are of "normal" weight but with one or more metabolic abnormalities also had an increased risk of CHD, cerebrovascular disease, heart failure and PVD compared to normal-weight individuals without metabolic abnormalities. (inquirer.net)
  • The secondary endpoint is the assessment of endothelial (dys) function by looking at ex vivo vascular reactivity and mRNA expression of endothelial cells from the wall of discarded segments of internal mammary artery. (frontiersin.org)
  • In an exploratory way, quercetin supplementation could also improve endothelial function by eliminating senescent vascular endothelial cells. (frontiersin.org)
  • High levels of inflammatory markers, such as C-reactive protein, were associated with left ventricular dysfunction ( 2 ), higher cardiovascular event rates ( 3 ) and worse clinical prognosis ( 4 ) following an acute myocardial infarction, independent of traditional risk factors. (frontiersin.org)
  • To determine if hyperuricemia and gouty arthritis are independent risk factors for acute myocardial infarction (MI) and, if so, whether they are independent of renal function, diuretic use, metabolic syndrome, and other established risk factors. (natap.org)
  • Thus, in theory, gout can be expected to increase the risk of acute myocardial infarction (MI). (natap.org)
  • Reduce the risk of non-fatal myocardial infarction and stroke. (globalrph.com)
  • 40-55%) are higher than the mortality rates due to ICU-related myocardial infarction (20%), sepsis without AKI (15-25%), or acute respiratory distress syndrome requiring mechanical ventilation (30-40%) [ 1 ]. (beds.ac.uk)
  • Although the overall incidence of stroke has declined in high-income countries 2 , the incidence of stroke among the younger populations has been rising globally 3 . (hku.hk)
  • To identify the risk factors of young stroke, the study also followed up with a cohort of 431 stroke patients aged from 18 to 55 years who were admitted to Queen Mary Hospital and Ruttonjee Hospital of Hong Kong between September 2019 and August 2022. (hku.hk)
  • Moreover, it was noted that sodium intake strongly correlated with systolic and diastolic blood pressure as well as 10-year projected stroke risk. (hku.hk)
  • These alarming findings call for stronger awareness and control of vascular risk factors leading to stroke, especially among the younger generations,' commented Dr Gary Lau Kui-kai, Director of HKU Stroke who leads the study. (hku.hk)
  • Consistent with other studies, our findings show that Chinese people tend to have a very high sodium intake, which is directly correlated with blood pressure and also projected stroke risk. (hku.hk)
  • Age-specific stroke rates are higher in men, but women experience more frequent stroke events because of their long life expectancy, and high stroke incidence at older ages [ 1 ]. (karger.com)
  • ICAS can have a large influence in China because its frequency is high [ 4 ] and it is associated with a high risk of recurrent stroke. (karger.com)
  • The Warfarin-Aspirin Symptomatic Intracranial Disease study, which was performed at 59 medical centers in North America and included 569 patients with symptomatic ICAS, showed that women had a significantly higher risk for IS and for the combined endpoint of stroke and vascular death [ 6 ]. (karger.com)
  • However, studies conducted in recent years indicate that elevated serum UA levels are an independent risk factor for stroke. (itmedicalteam.pl)
  • In Multiple Logistic Regression Analysis, serum UA levels higher than 5,6 mg/dL were identified as independent risk factors for ischemic stroke. (itmedicalteam.pl)
  • In our study, high UA levels were seen as an independent risk factor for stroke. (itmedicalteam.pl)
  • Tracz J, Gorczyca-Głowacka I, Wałek P, Rosołowska A, Wożakowska-Kapłon B. Risk factors of ischaemic stroke in patients with atrial fibrillation. (termedia.pl)
  • AF is associated with a nearly fivefold increased risk of stroke [3, 4]. (termedia.pl)
  • However, this risk may depend on the coexistence of several modifiable and non-modifiable factors that predispose to stroke and AF, such as age and vascular disease [5-7]. (termedia.pl)
  • This suggests that although AF itself is independently associated with stroke, when other risk factors are present the cause of stroke cannot be explained by arrhythmia alone [5, 9]. (termedia.pl)
  • This scale is used to help identify patients at low, moderate, and high risk of stroke [10, 11]. (termedia.pl)
  • Identification of risk factors for stroke in patients with AF is important to allow modification of some of them and to establish effective treatment. (termedia.pl)
  • The aim of the study was to assess which of the common risk factors are most strongly associated with the occurrence of stroke in patients with AF. (termedia.pl)
  • We compared baseline characteristics between these 2 groups and investigated risk factors for stroke patients with AF. (termedia.pl)
  • ACCENTUATE is studying patients with hyperlipidemia or diabetes. (wikipedia.org)
  • Because of their neuropsychiatric problems, such patients may be more prone to risk behavior (eg, unprotected intercourse), and they may pose a greater risk of transmission of the virus. (medscape.com)
  • 0.001) were significantly higher in RA patients than in controls. (researchgate.net)
  • Hyperlipidemic patients should be warned about the potential risks of herb-drug interactions, particularly those taking anticoagulants and antiplatelet drugs. (hindawi.com)
  • For patients that require a high-intensity statin or are unable to achieve their LDL-C goal receiving simvastatin 40 mg daily, prescribe alternative LDL-C lowering treatment. (nih.gov)
  • Chinese patients may be at higher risk for myopathy. (nih.gov)
  • Temporarily discontinue simvastatin in patients experiencing an acute or serious condition at high risk of developing renal failure secondary to rhabdomyolysis. (nih.gov)
  • Inform patients of the risk of myopathy and rhabdomyolysis when starting or increasing simvastatin dosage. (nih.gov)
  • A high prevalence of cutaneous disorders is expected, because most patients with ESRD have an underlying disease process with cutaneous manifestations. (medscape.com)
  • Our clinic has a high success rate for treating heart failure patients, and the statistics prove it. (sutterhealth.org)
  • Sedentary lifestyle, changing dietary habits and surge in associated risk factors are likely to increase the number of patients with cardiovascular diseases. (ipsnews.net)
  • In patients with coronary heart disease (CHD) or at high risk of CHD, ZOCOR® can be started simultaneously with diet. (globalrph.com)
  • Reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and triglycerides (TG), and to increase high-density lipoprotein cholesterol (HDL-C) in patients with primary hyperlipidemia (Fredrickson type IIa, heterozygous familial and nonfamilial) or mixed dyslipidemia (Fredrickson type IIb). (globalrph.com)
  • Reduce elevated TG in patients with hypertriglyceridemia (Fredrickson type lV hyperlipidemia). (globalrph.com)
  • Reduce elevated TG and VLDL-C in patients with primary dysbetalipoproteinemia (Fredrickson type lll hyperlipidemia). (globalrph.com)
  • Rosuvastatin treatment of patients with better than average lipid profiles but with elevated high-sensitivity C-reactive protein (hsCRP) resulted in a 44% relative risk reduction in cardiovascular events and a 20% reduction in all-cause mortality, reports Paul Ridker, MD (pictured), lead investigator for the JUPITER Trial Study Group. (medicaleconomics.com)
  • While many physicians try to improve identifying high-risk individuals by measuring hsCRP, a strategy of treating patients without established cardiovascular risk factors with statins remains controversial. (medicaleconomics.com)
  • Dr. Tonkin also points out that JUPITER patients did have other risks in that they were overweight and had a median systolic blood pressure of 134 mmHg. (medicaleconomics.com)
  • The ACC and American Heart Association (AHA) have released the ASCVD Risk Estimator, a mobile app to help health care providers and patients estimate 10-year and lifetime risks for atherosclerotic cardiovascular disease (ASCVD) using the Pooled Cohort Equations and lifetime risk prediction tools. (ccatlanta.com)
  • ICAS rates are disproportionately higher in Asian patients than in white patients [ 4 ]. (karger.com)
  • NEW YORK - In patients with type 2 diabetes, a reduction in retinal parafoveal vascular density may indicate coronary insufficiency and the potential for a cardiac event, according to a presenter. (nso-korpus.info)
  • Patients were then categorized by parafoveal RV into four quartiles, ranging from high RV (quartile one) to low RV (quartile four). (nso-korpus.info)
  • About half of the studied T2DM patients have high serum cholesterol level (52.5%), while 22.5% had low serum HDL- C levels and 39.2% had high serum triglyceride level, most of patients had serum LDL-C levels above normal range (67.5%), so the common patterns of dyslipidemia in this study were LDL-C followed by cholesterol. (heraldopenaccess.us)
  • However, patients with hyperlipidemia had a lower risk for severe outcome (aOR 0.17). (cdc.gov)
  • Our novel finding that Legionnaires' disease patients with hyperlipidemia had a lower risk for severe outcome deserves further study to confirm the observation and ascertain the underlying reason. (cdc.gov)
  • Vasileios Panoulas, MD, discusses a pooled analysis of factors predicting outcomes at 90 days in high-risk PCI patients. (heartrecovery.com)
  • The guidelines recommend insulin treatment in all patients who present with ketosis or extremely high blood glucose levels because it may not be clear initially whether these patients have type 2 or type 1 diabetes. (medscape.com)
  • Recognize that, in patients with PCOS who are receiving metformin, possible resumption of normal ovulation and menstrual cycles increases the risk of pregnancy. (medscape.com)
  • High triglycerides are associated with increased risk for CAD in patients with other risk factors, such as low HDL-cholesterol, some patient groups with elevated apolipoprotein B concentrations, and patients with forms of LDL that may be particularly atherogenic. (cdc.gov)
  • LDL-cholesterol is measured to assess risk for CHD and to follow the progress of patients being treated to lower LDL-cholesterol concentrations. (cdc.gov)
  • Elevated levels of Apo B are frequently found in patients withatherosclerotic vascular changes and are a risk factor for atheroscelerosis. (cdc.gov)
  • Il s'agit d'une étude transversale, monocentrique et descriptive, durant 12 mois, incluant les patients âgés d'au moins 18 ans admis en réanimation polyvalente pour un sepsis ou choc septique. (bvsalud.org)
  • Thus, prevention and treatment of hyperlipidemia are effective approaches to reduce the incident rate of chronic diseases. (hindawi.com)
  • There is a growing interest in TCM treatment of hyperlipidemia. (hindawi.com)
  • In the last few decades, hundreds of Chinese herbal medicines in the form of compounds, extracts, single herbs, or formulae have been reported to be effective for the prevention and treatment of hyperlipidemia [ 16 ], especially those high-fat diet (HFD) induced cases. (hindawi.com)
  • For instance, Crestor launched by Astrazeneca and indicated for the treatment of hyperlipidemia, lost patent in early 2016 and in April 2016, the U.S. FDA approved first generic to this drug to Watson Pharmaceuticals Inc. (ipsnews.net)
  • Conventional risk factors such as surgery · for clot in the inferior vena cava, Dop- do not account for all cases, and only a pler sonography or computed tomogra- fraction of those with these risk factors phy with venous phase contrast. (who.int)
  • In fact, hyperlipidemia is one of the risk factors of CVD [ 11 ], which becomes one of the major killers around the world. (hindawi.com)
  • In multivariable regressions in which the above risk factors were used as covariates, gout was found to be associated with a higher risk of acute MI (OR 1.26 [95% CI 1.14-1.40], P (natap.org)
  • Gouty arthritis is associated with an excess risk of acute MI, and this is not explained by its well-known links with renal function, metabolic syndrome, diuretic use, and traditional cardiovascular risk factors. (natap.org)
  • The Multiple Risk Factor Intervention Trial (MRFIT), a randomized primary cardiovascular prevention trial conducted and supported by the National Heart, Lung, and Blood Institute in collaboration with the MRFIT investigators, is one such study with the information on traditional and other confounding risk factors that has been unaccounted for in previous studies. (natap.org)
  • Myopathy and Rhabdomyolysis: Risk factors include age 65 years or greater, uncontrolled hypothyroidism, renal impairment, concomitant use with certain other drugs, and higher simvastatin dosage. (nih.gov)
  • Optimize vascular risk factors and focus on a healthy, active lifestyle. (unboundmedicine.com)
  • See "Risk Factors. (unboundmedicine.com)
  • According to the Centers for Disease Control and Prevention (CDC) of the U.S., high blood pressure, high cholesterol, and smoking are key risk factors for heart disease. (ipsnews.net)
  • About half of the population of the U.S. (47%) have at least one of these three risk factors. (ipsnews.net)
  • Since the prevalence of traditional CVD risk factors among law enforcement officers is similar to the general population, other mechanisms must be involved in this excessive morbidity. (cdc.gov)
  • Neither global CVD risk, expressed as the Framingham Risk Score, nor the number of metabolic syndrome risk factors differed between these two groups. (cdc.gov)
  • The key findings of this research project are 1) law enforcement officers may be at an increased risk for CVD due to a relatively pro-inflammatory vascular milieu but 2) this increased risk does not appear to be associated with either job -related stress or traditional CVD risk factors. (cdc.gov)
  • GDM represents one of the highest risk factors for developing T2DM. (nursekey.com)
  • With the same purpose, it is necessary to use mass media on a broader basis as well as disseminate published for population booklets and popular brochures on measures of control and prevention of cardio-vascular diseases, strengthening resistance of people to external negative impact and strengthening of protective factors. (who.int)
  • It is important to develop legislative acts on CVD risk factors control - ban on tobacco smoking, limitation of alcohol consumption - and public policy on healthy and safe nutrition as well as implement unified education program on healthy life style into the system of secondary and higher education. (who.int)
  • Risk factors for thrombosis and management strategies are briefly discussed. (ashpublications.org)
  • Two or more other CVD risk factors are present in the adolescent patient. (globalrph.com)
  • Two randomised controlled cross-over intervention studies investigating the effects of chronic and acute consumption of commercially-available fruit- and vegetable-puree-based drinks (FVPD) on bioavailability, antioxidant status and CVD risk factors are described. (cambridge.org)
  • There were no significant effects on oxidative stress, antioxidant status and other CVD risk factors. (cambridge.org)
  • Variations in risk factors among populations from different countries may explain differences in the ICAS incidence. (karger.com)
  • The relationships between Lp-PLA2 and other risk factors with re-stenosis were evaluated. (biomedcentral.com)
  • With multivariate analysis, after adjustment for other risk factors, Lp-PLA2 remained an independent predictor for re-stenosis with a hazard ratio of 1.140. (biomedcentral.com)
  • No synergistic effect between Lp-PLA2 and other risk factors for re-stenosis was found. (biomedcentral.com)
  • Baseline demographic and clinical characteristics including traditional risk factors and laboratory results were collected. (biomedcentral.com)
  • Dr. Sanghvi may recommend aneurysm screening if you have major risk factors. (njheartandvascularcare.com)
  • We study the molecular mechanisms of atherosclerotic cardiovascular disease with a particular focus on the role of redox signaling in vascular endothelial cell dysfunction in response to various risk factors including hyperlipidemia, aging, and chronic alcohol abuse, which are supported by NIH grants. (bu.edu)
  • to monitor the prevalence and trends in major cardiovascular conditions and risk factors in the U.S. (cdc.gov)
  • Introduction: Metabolic syndrome (MS) is a complex pathology that combines several risk factors for cardiovascular disease. (bvsalud.org)
  • Although HDL-C levels predict cardiovascular risk in the general population, the increased risk may be caused by other factors, such as accompanying lipid and metabolic abnormalities, such as hypertriglyceridemia, rather than the HDL-C level itself. (msdmanuals.com)
  • We don't know the mechanism, but it has been theorized to work through both the autonomic nervous system and endocrine system via a stress response that elevates key biological risk factors for cardiovascular disease such as blood pressure and cholesterol," she added. (medscape.com)
  • Factors such as inactivity and immobility may place people with MS at increased risk of developing disabilities, and they may be disproportionately affected by chronic diseases (1,2). (cdc.gov)
  • For more information on the Prevention Guidelines ASCVD Risk Estimator, visit the American College of Cardiology . (ccatlanta.com)
  • In adults with primary hyperlipidemia. (nih.gov)
  • If you do not have a diagnosis of high cholesterol or heart disease, this test may not be recommended for you. (medlineplus.gov)
  • Other disorders that may be associated with high apoB100 levels include atherosclerotic vascular disease such as angina pectoris (chest pain that occurs with activity or stress) and heart attack . (medlineplus.gov)
  • Apolipoprotein measurements may provide more detail about your risk for heart disease, but the added value of this test beyond a lipid panel is unknown. (medlineplus.gov)
  • It is thought that modifying lipoprotein levels modifies the risk of cardiovascular disease. (wikipedia.org)
  • Evacetrapib evaluation for treatment of high-risk vascular disease was discontinued due to lack of efficacy, as had already happened in the past with two other CETP inhibitors (torcetrapib and dalcetrapib) due to increased deaths and little identifiable cardiovascular benefit (despite substantial increases in HDL). (wikipedia.org)
  • Inflammation has emerged as a central mediator of endothelial dysfunction, and by extension, vascular disease ( 1 ). (frontiersin.org)
  • The amnestic subtypes are higher risk for progression to Alzheimer disease. (unboundmedicine.com)
  • Cardiovascular disease (CVD) accounts for a significant portion of this excess illness, with published prevalences as high as 1.7 times that of the general population. (cdc.gov)
  • AIMS: Dysfunction of adipose tissue increases the risk of cardiovascular disease. (bvsalud.org)
  • Well, for whatever reason, you may be concerned about your risk of getting heart disease. (stlukes-stl.com)
  • One study found that cholesterol deposits on the eyelids were associated with increased risk of heart attack and heart disease, even in people with normal lipid levels. (medicalnewstoday.com)
  • Diabetes and Vascular Disease Objectives: Describe 3 vascular conditions associated with diabetes. (slideserve.com)
  • Framingham score predicts the 10 year risk of cardiovascular disease. (medthical.com)
  • benefits of exercise include lowering of blood pressure, reduce bad cholesterol, increase good cholesterol, lose weight and reduce risk of death from cardiovascular disease. (medthical.com)
  • Therapy with lipid-altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia. (globalrph.com)
  • In 2003, the AHA and the Centers for Disease Control and Prevention concluded that hsCRP, at physician discretion, may be useful to determine the preventive measures needed for people at intermediate risk. (medicaleconomics.com)
  • It was not so long ago that cardiologists were warning us to avoid testosterone as they believed that it increased the risk of heart disease. (hippevo.com)
  • The amount of literature exploring this is rather robust and shows a clear picture that hypogonadism is not only correlated with inflammatory vascular disease but is causative in the progression to coronary disease. (hippevo.com)
  • We found that chronic renal failure/impairment (adjusted odds ratio [aOR] 4.09), chronic pulmonary diseases (aOR 3.22), malignancy (aOR 3.04), and heart diseases (aOR 2.15) were independently associated with a higher risk for severe Legionnaires' disease. (cdc.gov)
  • In 2016, CHP adopted a risk-based strategy for environmental investigation and sampling for Legionnaires' disease cases that environmental investigation and sampling from potential sources will be conducted only if certain criteria are met (e.g., definite nosocomial case). (cdc.gov)
  • Researchers in the United Kingdom are warning that those who are classed as "healthy obese," or who are a "normal weight" but have metabolic abnormalities such as diabetes, could still be at an increased risk of cardiovascular disease. (inquirer.net)
  • In the largest study of its kind to date, a team from the University of Birmingham's Institute of Applied Health Research set out to compare weight and metabolic status to the risk of cardiovascular disease. (inquirer.net)
  • CD31 as a probable responding and gate-keeping protein of the blood-brain barrier and the risk of Alzheimer's disease. (bu.edu)
  • This system does not take into account specific lipoprotein abnormalities (eg, low HDL-C or high LDL-C) that may contribute to disease despite normal cholesterol and TG levels. (msdmanuals.com)
  • There are many environmental risks, such as air pollution, that can affect cardiovascular disease, and loud noise is an added factor that we should start to pay attention to," she added. (medscape.com)
  • An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention. (cdc.gov)
  • Association of APOL1 Risk Alleles with Cardiovascular Disease in African Americans in the Million Veteran Program. (cdc.gov)
  • Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study. (cdc.gov)
  • Explanatory variables (eg, age, education, race) and dynamic associations between conditions (higher odds for each when 1 of the other conditions were present) for chronic disease in men with MS were similar to findings in the general population literature for select conditions. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) uses the Behavioral Risk Factor Surveillance System (BRFSS) to compile chronic disease prevalence data for the US population, but data specific to people with MS are unavailable. (cdc.gov)
  • The BRFSS survey is a standardized instrument used to monitor disease, health, and risk behaviors in the US population (50 states, the District of Columbia, Puerto Rico, Guam, and the US Virgin Islands). (cdc.gov)
  • Six countries in the Middle East are rated among the top 10 countries in the world with the highest prevalence of diabetes [5]. (heraldopenaccess.us)
  • Fasting blood sugar (FBS), triglyceride (TG), total cholesterol (TC), low and high density lipoprotein (LDL, HDL), glycated haemoglobin HbA(Ic) and serum insulin were measured before and after vitamin C consumption and the results were analyzed. (amrita.edu)
  • Plasma lipid profile, insulin resistance, fatty liver, and atherosclerotic lesions were observed after 12 weeks of the atherogenic high-fat diet (HFD) feeding. (bvsalud.org)
  • Hyperlipidemia comprises a heterogeneous group of disorders, characterized by high levels in one or more lipids and/or lipoproteins [atherogenic free fatty acids (FA), triglycerides (TG) (hypertriglyceridemia), small dense low-density lipoprotein cholesterol (LDL-C) (hypercholesterolemia), and apolipoprotein (apo) B], and/or low level in antiatherogenic high density lipoprotein cholesterol (HDL-C), in the circulation [ 1 - 3 ]. (hindawi.com)
  • Special attention will be paid to prevention of cardio-vascular diseases, reduction of micronutrient insufficiency, stabilization of infectious diseases incidence rate including TB, malaria, helminthiasis, brucellosis, restriction of dissemination of HIV/AIDS and immunization-sensitive infections. (who.int)
  • For example, in familial combined hyperlipidemia, expression may occur only in the presence of significant secondary causes. (msdmanuals.com)
  • Doctors label lipid disorders based on the type of high cholesterol you have. (upmc.com)
  • Cardiovascular diseases (CVDs) comprise disorders and conditions related to circulatory system which include heart and vascular system. (ipsnews.net)
  • Al lomicrons, low-density lipoproteins (LDL), Muhtaseb's study of Arab women indi- very-low-density lipoproteins (VLDL) and cated an incidence of 50% of lipid disorders high-density lipoproteins (HDL). (who.int)
  • For example, high HDL-C levels caused by some genetic disorders may not be associated with a lower risk of cardiovascular disorders, and low HDL-C levels caused by some genetic disorders may not be associated with an increased risk of cardiovascular disorders. (msdmanuals.com)
  • However, significant cardiovascular risk reduction and conduit arterial elasticity did not improve. (medscape.com)
  • Dyslipidaemia is a wider terminology that also includes low levels of good cholesterol namely the high-density lipoprotein cholesterol (HDL-C). (medthical.com)
  • In the general population, evidence is less strong for a benefit from lowering elevated TG and increasing low high-density lipoprotein cholesterol (HDL-C) levels. (msdmanuals.com)
  • Because of additive effects of hyperglycaemia and hyperlipidaemia for cardiovascular diseases, lipid abnormalities should be evaluated in diabetes. (amrita.edu)
  • Reported fleaborne typhus cases in Los Angeles County have been increasing since 2010, with the highest number (171) reported during 2022. (cdc.gov)
  • Sutter's network of cardiologists can help you adopt the health habits you need to reduce your risk of future heart-related problems. (sutterhealth.org)
  • To reduce high blood pressure. (mskcc.org)
  • Well, a few tests can help you learn that risk, so you can start making healthy lifestyle changes to reduce it. (stlukes-stl.com)
  • However, treating dyslipidemia is essential, because it can reduce the risk of heart problems. (medicalnewstoday.com)
  • Reduce the risk of total mortality by reducing CHD deaths. (globalrph.com)
  • This app was designed as a companion tool to the 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk and the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults. (ccatlanta.com)
  • If finally corroborated, we believed that in the future lowering Lp-PLA2 level with its specific antagonist would definitely reduce the risk of re-stenosis and doubtless improve the outcomes of patient with CAD. (biomedcentral.com)
  • Dyslipidemia increases the risk of cholesterol building up on the walls of arteries. (medicalnewstoday.com)
  • CETP collects triglycerides from very low-density lipoproteins (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa, but primarily increasing high-density lipoprotein and lowering low-density lipoprotein. (wikipedia.org)
  • Familial lipid syndrome means your body doesn't process cholesterol correctly, which can lead to severely high levels of LDL cholesterol or triglycerides. (upmc.com)
  • Familial dysbetalipoproteinemia: High total cholesterol and high triglycerides. (upmc.com)
  • Familial hypertriglyceridemia: High triglycerides. (upmc.com)
  • We found that compared with Ldlr-/- mice, Agpat2-/-Ldlr-/- mice showed significantly higher plasma total cholesterol and triglycerides after HFD feeding. (bvsalud.org)
  • Combined hyperlipidemia refers to the condition whereby the total cholesterol and triglycerides are both raised. (medthical.com)
  • When the triglycerides are highly raised there will be a risk of pancreatitis and patient may experience extreme epigastric pain , nausea, vomiting , fever and even jaundice. (medthical.com)
  • Very high triglycerides can result in pancreatitis. (cdc.gov)
  • Mean Hcy level was significantly higher in the test group. (who.int)
  • Approximately 55.1% and 58.5% of participants in normal and elevated groups presented with acute coronary syndrome, and the percentage of tri-vessels stenoses was significantly higher in elevated group (40.8% vs 32.1%, P = 0.016). (biomedcentral.com)
  • While the magnitude of the observed outcomes differed between these trials, altogether, their findings suggest that a conventional management coupled with inflammation inhibition could maximize vascular benefit and clinical outcomes ( 6 - 8 ). (frontiersin.org)
  • Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive use. (nih.gov)
  • Heterozygous familial hypercholesterolemia: High total cholesterol. (upmc.com)
  • Long-Term Cardiovascular Risk in Heterozygous Familial Hypercholesterolemia Relatives Identified by Cascade Screening. (cdc.gov)
  • Law enforcement officers have higher all-cause morbidity and mortality than the general population. (cdc.gov)
  • This high mortality rate is attributed to the systemic impact of AKI on the brain, heart, lungs, liver, and gastrointestinal tract, linking AKI to various syndromes (Additional file 1 ) [ 2 ]. (beds.ac.uk)
  • Methods We completed a cost-effectiveness analysis based on a decision-analytic model to assess smokers hospitalised in Ontario, Canada for AMI, UA, HF, and COPD, their risk of continuing to smoke and the effects of quitting on re-hospitalisation and mortality over a 1-year period. (bmj.com)
  • Fasting levels of high-sensitivity growth hormone predict cardiovascular morbidity and mortality: the malmö diet and cancer study. (lu.se)
  • The mortality is very high. (bvsalud.org)
  • Therefore, this research project tested the hypotheses that 1) compared to the general population, law enforcement officers have higher levels of pro-atherogenic inflammatory mediators and lower levels of anti-atherogenic inflammatory mediators and 2) job -related stress is associated with these differences. (cdc.gov)
  • However, the risk factor of increased inflammatory mediators is novel, nontraditional, and not routinely assessed in most physicians' offices. (cdc.gov)
  • The simple construct is that inflammatory lifestyle drives a rising CRP and this in turn increases coronary risk, while this same lifestyle directly contributes to hypogonadism. (hippevo.com)
  • The systolic pressure is high because the heart must beat hard & crank up the pressure in order to force the blood through potentially narrowed vasculature. Blood pressure measures pressure, not volume, although the two are distinctly related. This low diastolic ties in with #1. (neuroems.com)
  • A more recent article on high blood pressure in children and adolescents is available. (aafp.org)
  • See related handout on managing high blood pressure in children , written by the authors of this article. (aafp.org)
  • High blood pressure in children and adolescents is a growing health problem that is often overlooked by physicians. (aafp.org)
  • Or, it could be that you smoke, or your blood pressure is too high. (stlukes-stl.com)
  • Worksite health and wellness programs that include screenings for high blood pressure and cholesterol should also target noise-exposed workers. (medscape.com)
  • For anyone in an environment with increased noise levels, it's not just hearing loss that we have to think about, but there may in fact be some risk for high blood pressure and high cholesterol. (medscape.com)
  • Familial defective apolipoprotein B-100: High total cholesterol. (upmc.com)
  • 1. Total cholesterol when raised increased your risk of getting cardiovascular diseases. (medthical.com)
  • A total cholesterol level of 200 to 239 mg/dL (5.17 to 6.18 mmol/L) is borderline high . (medthical.com)
  • A total cholesterol level greater than or equal to 240 mg/dL (6.21 mmol/L) is high . (medthical.com)
  • Hyperuricemia was an independent risk factor for acute MI in the multivariable regression models, with an odds ratio (OR) of 1.11 (95% confidence interval [95% CI] 1.08-1.15, P (natap.org)
  • In separate analyses, a relationship between gout and the risk of acute MI was evident among those with and without those hyperuricemia. (natap.org)
  • The independent risk relationship between hyperuricemia and acute MI is confirmed. (natap.org)
  • Increased risk for venous thrombosis was found among those under 50 having both lipid abnormalities. (who.int)
  • Most often, this test is done to help determine the cause or specific type of high blood cholesterol. (medlineplus.gov)
  • In a statement issued today, American Heart Association president Timothy Gardner, MD, said, "(JUPITER) was not designed to answer the question of whether the impact on risk was due to a reduction in inflammation or a reduction in LDL. (medicaleconomics.com)
  • Recent developments have placed high dimensional flow cytometry at the forefront of new applications critical for the pharmaceutical sector and clinical laboratories. (europeanpharmaceuticalreview.com)
  • While genomics, proteomics and metabolomics are familiar to most investigators, and even clinicians, cytomics, facilitated by high dimensional, single cell analysis is becoming a technology of choice for the elucidation of relevant phenotypic patterns that can be directly utilised in the clinical arena (Figure 1). (europeanpharmaceuticalreview.com)
  • But although both ECLAP and MRC PT1 inform clinical management and allude to the complexities of thrombosis we still lack fundamental knowledge, and our understanding of thrombosis in these conditions has not paralleled advances in the field of thrombosis and vascular biology. (ashpublications.org)
  • It aims to publish the highest quality material, both clinical and scientific, on all aspects of medicine. (itmedicalteam.pl)
  • Most of the circulating cholesterol is found in three major lipoprotein fractions: very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL). (cdc.gov)
  • We then test in both animals and in human intervention studies if manipulation of such molecular disturbances ameliorate cardiometabolic risk. (lu.se)
  • Nevertheless, the incidence of re-stenosis was marginally higher in elevated Lp-PLA2 group (8.5% versus 4.6%, P = 0.047). (biomedcentral.com)
  • The only lomicrons are raised only after eating a Sudanese study indicated a high incidence fat-containing meal. (who.int)
  • Using this medicine increases the risk of blood coagulation which may worsen your condition. (practo.com)
  • To lower high cholesterol levels. (mskcc.org)
  • If the cholesterol levels still high despite diet and exercise regimes , to prevent risk of cardiovascular diseases , medications will be started as benefits outweighs risk. (medthical.com)
  • HDL cholesterol , or high-density lipoprotein, is the "good cholesterol" that hunts down and absorbs bad cholesterol. (upmc.com)
  • An abnormal result may mean you have high lipid (fat) levels in your blood. (medlineplus.gov)
  • For someone with the disorder, LDL levels are high from birth or childhood. (upmc.com)
  • Without treatment, levels get higher over time. (upmc.com)
  • It's rare, but when both parents pass on the gene to their child, LDL levels are dangerously high. (upmc.com)
  • A coronary risk profile is a group of blood tests that measure your cholesterol and triglyceride levels. (stlukes-stl.com)
  • A person with one of these conditions may have abnormally high lipid levels despite being in otherwise good health. (medicalnewstoday.com)
  • Hyperlipidemia is a term to describe a medical condition whereby the blood levels of cholesterol are raised. (medthical.com)
  • Higher levels of LDL has been highly associated with cardiovascular diseases. (medthical.com)
  • HDL-C levels do not always predict cardiovascular risk. (msdmanuals.com)
  • The global burden of CVD is beginning to be viewed as high as infectious diseases [ 13 ]. (hindawi.com)