• Legg-Calvé-Perthes (LCPD) disease is a childhood hip disorder that results in infarction of the bony epiphysis of the femoral head. (medscape.com)
  • Legg - Calve - Perthes Disease (LCPD) is a necrosis of the femoral head which affects the range of motion of the hips. (nih.gov)
  • Although the majority of these disorders are self-limited and require only rest and pain control, all patients with possible diagnoses of Legg-Calve-Perthes disease (interruption of vascular supply to the femoral head) or Scheuermann disease (disturbance of the vertebral end plates causing kyphosis, or humpback deformity) should be referred for orthopedic evaluation. (blogspot.com)
  • Among the more common articular osteochondroses are Köhler disease of the tarsal navicular, Legg-Calve-Perthes disease of the femoral head, and Panner disease of the humeral capitellum. (medscape.com)
  • Legg believed the cause was impairment of blood supply to the femoral epiphysis, Calvé believed rickets, and Perthes deduced an infection possibly causing degenerative arthritis leads to LCP disease. (wikipedia.org)
  • Freiberg disease in adolescents is thought to belong to a group of related diseases involving growth disturbances of the epiphysis or apophysis, collectively termed the osteochondroses . (medscape.com)
  • The causes of hip pain in children may be caused by conditions unique to the growing skeleton, including Perthes' disease, slipped capital femoral epiphysis (SCFE), and apophyseal avulsion fractures of the pelvis. (medicalcitykidsortho.com)
  • Legg-Calvé-Perthes disease (LCPD) is a childhood hip disorder initiated by a disruption of blood flow to the head of the femur. (wikipedia.org)
  • He believed that individuals so predisposed would get Legg-Perthes disease after they sustained an injury (i.e., infection or trauma) to the hip. (teachmeorthopedics.info)
  • Bilateral Perthes, which means both hips are affected, should always be investigated to rule out multiple epiphyseal dysplasia. (wikipedia.org)
  • in histology, the proliferation of articular cartilage with the presence of vascular granulation regenerative tissue, with osteoclasts and fibrocartilaginous tissue in the metaphyseal femoral neck region was identified. (bvsalud.org)
  • Legg-Calvé-Perthes syndrome is a disorder of the hip in young children. (teachmeorthopedics.info)
  • Gaucher disease (GD) encompasses a continuum of clinical findings from a perinatal lethal disorder to an asymptomatic type. (nih.gov)
  • HbSC disease is a milder sickling disorder. (medscape.com)
  • Freiberg disease is a form of avascular necrosis (AVN) in the metatarsal. (medscape.com)
  • Cervical vertebrae 1,2, …?Ca: Calcium?Ca: Cancer?Ca: Carcinoma?Ca: Cardiac arrest?Ca: Coronary artery?CA-125: A tumor marker for ovarian cancer?CAB: Cellulose acetate butyrate?CABG: Coronary artery bypass graft?CACI: Computer-Assisted Continuous Infusion?CAD: Coronary artery disease?CAG: ?CAH: Chronic active hepatitis?CAH: Congenital adrenal hyperplasia?calid. (kuwaitpharmacy.com)
  • Staging of the disease is based on plain radiographic findings. (medscape.com)
  • Plain radiographic findings may be entirely normal in early symptomatic disease. (medscape.com)
  • Radiographic changes consistent with AVN have led some authors to suggest that the inciting event is an injury to the vascular supply to the MT head. (medscape.com)
  • GD type 1 is characterized by the presence of clinical or radiographic evidence of bone disease (osteopenia, focal lytic or sclerotic lesions, and osteonecrosis), hepatosplenomegaly, anemia and thrombocytopenia, lung disease, and the absence of primary central nervous system disease. (nih.gov)
  • The disease is bilateral in 10-20% of patients and usually affects children aged 4-8 years. (medscape.com)
  • Typically, the disease is only seen in one hip, but bilateral Perthes is seen in about 10% of children diagnosed. (wikipedia.org)
  • It is important to be aware that persons who have immigrated into the U.S. illegally, while having much in common with legal immigrants, will be less likely to have received examinations, immunizations, and infectious disease screenings recommended in domestic refugee health guidelines from the Centers for Disease Control and Prevention. (blogspot.com)
  • PMID- 669649 TI - National disease prevention strategy needed, Kennedy conferees conclude. (nih.gov)
  • The Vascular Quality Initiative Cardiac Risk Index for prediction of myocardial infarction after vascular surgery. (mainehealth.org)
  • Legg-Calvé-Perthes disease remains one of the most controversial topics in all of pediatric orthopaedic surgery. (teachmeorthopedics.info)
  • In the late 19th century, however, Hugh Owen Thomas ( 6 ), Baker ( 7 ), and Wright ( 8 ) described patients with supposed hip joint infections that resolved without surgery, whose histories were consistent with Legg-Calvé-Perthes disease. (teachmeorthopedics.info)
  • Children affected by LCP disease often display uneven gait and limited range of motion, and they experience mild to severe pain in the groin area. (wikipedia.org)
  • Symptoms of HbSC disease are similar to SCD but less frequent and less severe. (medscape.com)
  • Recent findings, discussed in this chapter's section on pathogenesis, suggest that Legg-Calvé-Perthes "disease" may more appropriately be called a syndrome. (teachmeorthopedics.info)
  • Sundt ( 14 , 15 ) published the first monograph on Legg-Calvé-Perthes syndrome, reporting on 66 cases and the pathology of the condition. (teachmeorthopedics.info)
  • Although all refugees must pass an overseas medical screening examination to be admitted to the U.S., they often present to family physicians with musculoskeletal and pain issues, mental and social health problems, infectious diseases , and undiagnosed chronic conditions. (blogspot.com)
  • Waldenstrom ( 13 ) suggested the use of the term coxa plana to make the description of the disease consistent with that of other hip deformities, such as coxa vara and coxa valga. (teachmeorthopedics.info)
  • na histologia, identificamos a proliferação da cartilagem articular com presença de tecido regenerativo vascular de granulação, com osteoclastos e tecido fibrocartilaginoso na região metafisária do colo femoral. (bvsalud.org)
  • Perthes is a form of osteochondritis which affects only the hip. (wikipedia.org)
  • Kawasaki Disease is a multisystem inflammatory disease that affects mostly infants and children. (uchicago.edu)
  • Most current theories center on whether the initial insult is primarily traumatic or vascular. (medscape.com)
  • LCP disease is a vascular restrictive condition of idiopathic nature. (wikipedia.org)
  • Sickle cell disease (SCD) usually manifests early in childhood. (medscape.com)
  • Pain crises constitute the most distinguishing clinical feature of sickle cell disease and are the leading cause of emergency department visits and hospitalizations for affected patients. (medscape.com)
  • Sickling variants and sickle trait must be distinguished from HbS disease. (medscape.com)
  • Unlike sickle cell disease, which causes splenic infarction, Gaucher disease causes splenomegaly. (medscape.com)
  • Pecker LH, Lanzkron S. Sickle Cell Disease. (medscape.com)
  • Shatat IF, Jakson SM, Blue AE, Johnson MA, Orak JK, Kalpatthi R. Masked hypertension is prevalent in children with sickle cell disease: a Midwest Pediatric Nephrology Consortium study. (medscape.com)
  • In its juvenile osteochondrosis form, Freiberg disease is a degenerative process involving the epiphyses that results in osteonecrosis of subchondral cancellous bone. (medscape.com)
  • Gaucher disease also expands the marrow cavity and causes bone marrow infarction. (medscape.com)
  • He also noted that farther away from the main disease process, the marrow was fibrotic with inflammatory infiltrates. (teachmeorthopedics.info)
  • The February 1st issue of AFP contains copies of the new Child and Adolescent and Adult immunization schedules from the Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (ACIP). (blogspot.com)
  • Although Freiberg disease was originally described more than a century ago, the etiology and the most appropriate treatment remain controversial. (medscape.com)
  • [ 3 ] Despite several thoughtful investigations into the etiology of Freiberg disease, no consensus exists as to what type of disease process this peculiar affliction represents. (medscape.com)
  • Em crianças com mais de oito anos de idade, grupos III e IV com colapso do ABSTRACT Legg-Calvé-Perthes ( LCP ) disease is still an orthopedic enigma, because of its unclear etiology, its uncertain evolu- tion, and, overall, its treatment. (vdocuments.mx)
  • A trial of conservative treatment can be implemented for most patients presenting with Freiberg disease. (medscape.com)
  • Consid- ering the natural history of LCP disease, about 60% of the patients satisfactorily evolve with no future problems. (vdocuments.mx)
  • The clinically important diseases involved, observed in patients in the United States, are HbSC and Hb-beta thalassemia. (medscape.com)
  • Computed tomography (CT) scans allow early diagnosis of bone collapse and curvilinear zones of sclerosis early in the disease process, when plain radiography is less sensitive. (medscape.com)
  • The diagnosis of HbSC disease is made with Hb electrophoresis. (medscape.com)
  • The major morbidity and mortality from Kawasaki Disease is in the development of coronary artery aneurysms, which is why diagnosis and timely treatment is critical. (uchicago.edu)
  • Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Statement for Health Professionals From the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. (uchicago.edu)
  • Perthes simultaneously reported six cases of what he termed "arthritis deformans juveniles. (teachmeorthopedics.info)
  • Disorders that may affect blood supply (eg, diabetes mellitus , systemic lupus erythematosus , and hypercoagulability ) have been suggested factors in the development of Freiberg disease. (medscape.com)
  • Treatment and management strategies are similar to those employed in Hb S disease. (medscape.com)
  • Intermittent vaso-occlusive crises may be superimposed, or chronic low-level pain may be the only expression of the disease. (medscape.com)
  • Although no one has identified the cause of Perthes disease, a reduction in blood flow to the joint is known. (wikipedia.org)
  • Although regarding Freiberg disease as an osteochondrosis makes sense, it does not fully explain the adult-onset form of the disease, which may reflect a different process altogether, albeit a radiographically similar one. (medscape.com)
  • Whether this is the result of a direct vascular injury or of repetitive injury to an area that has an inherently poor blood supply is unknown. (medscape.com)
  • (3) Characteristics suggesting disease other than Kawasaki disease include exudative conjunctivitis, exudative pharyngitis, discrete intraoral lesions, bullous or vesicular rash, or generalized adenopathy. (uchicago.edu)
  • Unlike other osteochondroses, Freiberg disease is not commonly associated with steroid use, alcoholism, or smoking. (medscape.com)
  • Evaluation of suspected incomplete Kawasaki disease. (uchicago.edu)
  • Since Freiberg's original description, multiple authors have written about this uncommon condition, which has since come to be known as Freiberg disease. (medscape.com)
  • Approximately half the individuals with homozygous Hb S disease experience vaso-occlusive crisis. (medscape.com)
  • The disease is theorized to include the artery of the ligamentum teres femoris being constricted or even blocked too early, not allowing for time when the medial circumflex femoral artery takes over. (wikipedia.org)
  • Perthes is generally diagnosed between 5 and 12 years of age, although it has been diagnosed as early as 18 months. (wikipedia.org)