Arthritis, RheumatoidArthritisGenotypeDisease SusceptibilityGenetic Predisposition to DiseaseArthritis, ExperimentalPolymorphism, Single NucleotideArthritis, InfectiousSynovial MembraneArthritis, JuvenileAntirheumatic AgentsAllelesPolymorphism, GeneticSynovial FluidGenetic VariationRheumatoid FactorHaplotypesGene FrequencyArthritis, PsoriaticJointsCase-Control StudiesGeneticsGenome-Wide Association StudyArthritis, ReactiveHLA-DRB1 ChainsPhenotypeSynovitisOsteoarthritisHLA-DR AntigensMethotrexateAutoantibodiesGenetic MarkersLinkage DisequilibriumMolecular Sequence DataGenetics, PopulationGenetic LinkageSeverity of Illness IndexChromosome MappingMutationAutoimmune DiseasesBlood SedimentationTumor Necrosis Factor-alphaMice, Inbred DBAPolymerase Chain ReactionLupus Erythematosus, SystemicModels, GeneticSulfasalazineImmunoglobulin GSequence Analysis, DNARheumatoid NoduleGenome, HumanMetacarpophalangeal JointGenetic Association StudiesMicrobial Sensitivity TestsPeptides, CyclicGold Sodium ThiomalateHLA-DQ AntigensRisk FactorsArthrographySpondylitis, AnkylosingBase SequenceEpistasis, GeneticGenetic LociRheumatologyRheumatic DiseasesCohort StudiesWrist JointAntibodies, MonoclonalQuantitative Trait LociAmino Acid SequenceHLA-DQ beta-ChainsHLA-DR4 AntigenGenetic TestingTreatment OutcomeCrohn DiseaseDisease Models, AnimalEuropean Continental Ancestry GroupAsian Continental Ancestry GroupMicrosatellite RepeatsHLA AntigensHLA-DR3 AntigenNod2 Signaling Adaptor ProteinFinger JointImmunity, InnateCells, CulturedPedigreeHomozygoteBiological MarkersGenetic Diseases, InbornMice, Inbred C57BLCollagen Type IIPolymorphism, Restriction Fragment LengthPlant DiseasesCytokinesTime FactorsAnti-Bacterial AgentsHeterozygoteComplement C4aCitrullineReceptors, Tumor Necrosis Factor