• branched-chain
  • Valine, like other branched-chain amino acids, is synthesized by plants, but not by animals. (wikipedia.org)
  • Racemic valine can be synthesized by bromination of isovaleric acid followed by amination of the α-bromo derivative HO2CCH2CH(CH3)2 + Br2 → HO2CCHBrCH(CH3)2 + HBr HO2CCHBrCH(CH3)2 + 2 NH3 → HO2CCH(NH2)CH(CH3)2 + NH4Br Valine, like other branched-chain amino acids, is associated with insulin resistance: higher levels of valine are observed in the blood of diabetic mice, rats, and humans. (wikipedia.org)
  • whereas
  • According to IUPAC, carbon atoms forming valine are numbered sequentially starting from 1 denoting the carboxyl carbon, whereas 4 and 4' denote the two terminal methyl carbons. (wikipedia.org)
  • comes
  • The name valine comes from valeric acid, which in turn is named after the plant valerian due to the presence of the acid in the roots of the plant. (wikipedia.org)
  • levels
  • Mice fed a valine deprivation diet for one day have improved insulin sensitivity, and feeding of a valine deprivation diet for one week significantly decreases blood glucose levels. (wikipedia.org)