OrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceHealth CareGeographicals
Borrelia InfectionsBorreliaBorrelia burgdorferiIxodesTick InfestationsLyme DiseaseBorrelia burgdorferi GroupArachnid VectorsSlovakiaRelapsing FeverFlagellinDisease ReservoirsTicksDNA, BacterialPolymorphism, Restriction Fragment LengthPolymerase Chain ReactionBacterial Outer Membrane ProteinsPhylogenyRNA, Ribosomal, 16SMolecular Sequence DataSpecies SpecificityBacterial VaccinesSequence Analysis, DNALyme Disease VaccinesLipoproteinsAntibodies, BacterialAntigens, BacterialErythema Chronicum MigransPeromyscusLyme NeuroborreliosisMice, Inbred C3HAntigens, SurfaceSpirochaetalesOrnithodorosTick-Borne Diseases
GariniiBurgdorferi sensu latoAfzeliiBacteriaMiyamotoiLymeSpeciesSpielmaniiPathogensTicks collectedSpirochetesAntibodiesClinicalPrevalenceHumansComplexStudyRatesWeeksSensu latoGenospeciesPolymerase chain reTicksGeneticStrainsStrainIsolatesBabesiaLyme borreliosisIxodesRickettsiaPatientsChronicMultipleDiseaseSpecificHighCasesLevels
Garinii8
  • B. afzelii, B. garinii and B. valaisiana) a pronounced heterogeneity was found for OspA and OspC. (altmeyers.org)
  • Five Borrelia species were identifed: B. garinii, B. burgdorferi sensu stricto, B. afzelii, B. valaisiana, B. lusitaniae, and six mixed infections were also obtained. (archive.org)
  • 10°C ± 1°C, and all nymphs and adults were identified to afzelii , B. garinii , B. valaisiana , B. bissettii , and B. lusita- species. (cdc.gov)
  • Although B. bavariensis [7] (formerly the B. garinii OspA serotype 4) and B. spielmanii are known to cause disease, B. bissettii and B. valaisiana have only been shown to be involved in individual cases of Lyme disease [6]. (lymediseaseaction.org.uk)
  • In Europe there is evidence that the EM caused by B. afzelii infections is more often ring-like, with clearing in the centre, whereas the rash caused by B. garinii and B. burgdorferi s.s. was found to be often smaller and without the central clearing. (lymediseaseaction.org.uk)
  • Clinical appearance of erythema migrans caused by Borrelia afzelii and Borrelia garinii- effect of the patient's sex. (lymediseaseaction.org.uk)
  • Lyme disease (or borreliosis) is a tick-borne infection caused by certain species of the Borrelia genus ( B. burgdorferi in the US, predominantly B. afzelii and B. garinii in Asia and Europe). (amboss.com)
  • Borrelia garinii, Borrelia miyamotoi, Crimean-Congo hemorrhagic fever virus, Coxiella burnetii, Rickettsia monacensis and tick-borne encephalitis virus. (bvsalud.org)
Burgdorferi sensu lato2
  • In the present study, the density of questing Ixodes ricinus ticks and their infection with Borrelia burgdorferi sensu lato (sl) was examined in 11 areas located on the Swiss Plateau and in an alpine valley. (archive.org)
  • Also, the infection rates and distributions of these symbionts were compared to the horizontally transmitted pathogens Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum , and Neoehrlichia mikurensis . (biomedcentral.com)
Afzelii2
  • Skin manifestations such as acrodermatitis atrophicans, on the other hand, are mainly attributed to infections with B. afzelii. (altmeyers.org)
  • The highest tick-borne pathogen diversity was detected in domestic animals, and 12 species were shared between humans, wildlife, and domestic hosts, highlighting the following zoonotic species: Anaplasma phagocytophilum, Babesia divergens, Babesia microti, Borrelia afzelii, Borrelia burgdorferi s.s. (bvsalud.org)
Bacteria8
  • Anaplasmataceae and Borrelia burgdorferi s.l. are important tick-borne bacteria maintained in nature by transmission between ticks and vertebrate hosts. (biomedcentral.com)
  • Observed microorganism co-infection rates suggest that the risk of infection with one tick-borne bacterium is not independent of other bacteria [ 30 ]. (biomedcentral.com)
  • Furthermore, Borrelia bacteria prefer to adhere to different lymphatic fluids. (altmeyers.org)
  • The BmpA protein (Borrelia membran protein A) seems to play an important role in the adherence of Borrelia bacteria (Verma et al. (altmeyers.org)
  • A number of conserved Borrelia proteins, such as heat shock proteins and parts of flagellin have epitopes that are also found on other bacteria. (altmeyers.org)
  • Knowledge of Borrelia is expanding as better tools to analyse the bacteria are becoming more widely used. (lymediseaseaction.org.uk)
  • The genus Borrelia is a member of the larger family of bacteria called Spirochaetes which were originally thought to be spiral shaped. (lymediseaseaction.org.uk)
  • Spread by Ticks Caused by bacteria (borrelia) (Borrelia Burgdorferi) It causes borreliosis (lymes disease) The disease is multisystemic - involvement of skin, heart, joints and CNS Affects mostly young and middle-aged people. (slideserve.com)
Miyamotoi10
  • We confirmed infection of 2 patients with Borrelia miyamotoi in Japan by retrospective surveillance of Lyme disease patients and detection of B. miyamotoi DNA in serum samples. (cdc.gov)
  • Borrelia miyamotoi , which is genetically grouped with relapsing fever borreliae, was recently identified as a human pathogen in Russia ( 1 ), the United States ( 2 - 4 ), and Europe ( 5 ). (cdc.gov)
  • In areas of Japan to which Lyme disease is endemic, wild rodents have been found to be infected with B. miyamotoi ( 7 ), although no human infections have been confirmed. (cdc.gov)
  • We conducted a retrospective investigation to identify occult cases of human infections with B. miyamotoi in Japan. (cdc.gov)
  • Our retrospective investigation identified 2 cases of B. miyamotoi infection. (cdc.gov)
  • The central Europe are distributed broadly, whereas those that prevalence of B. miyamotoi infection in Japan, however, are less frequently found appear to be place-specific. (cdc.gov)
  • All of these Borrelia species cause human disease, and this is the first time that B . miyamotoi has been detected in Ireland. (invisible.international)
  • In addition, B. miyamotoi , one of the relapsing fever Borrelia species has been identified in Europe [3] and is known to be present in UK ticks [4]. (lymediseaseaction.org.uk)
  • Borrelia miyamotoi in host-seeking Ixodes ricinus ticks in England. (lymediseaseaction.org.uk)
  • Borrelia miyamotoi, transmitted by Ixodes spp. (bvsalud.org)
Lyme6
Species2
Spielmanii1
  • Rarely B. valaisiana , B. lusitaniae , B. spielmanii , and B. bavariensis infect humans. (amboss.com)
Pathogens2
  • In this paper we show the role of sand lizard ( Lacerta agilis ) in the transmission cycle of important tick-borne pathogens, Anaplasmataceae and Borrelia burgdorferi s.l. (biomedcentral.com)
  • Studies have shown that the gut microbiota of the black-legged tick, I. scapularis , modulates the integrity of the peritrophic matrix that separates the lumen from the digestive cells of the gut and subsequently affects the establishment of Borrelia pathogens [ 7 ]. (biomedcentral.com)
Ticks collected1
  • The overall rate of borrelial infection in ticks collected at six sites in Ireland was 5%, with a range from 2% to 12%, depending on the locations of tick collection. (invisible.international)
Spirochetes2
  • Viral fever-like spirochetes and estimated how prevalent such agents include those of tick-borne encephalitis, Russian infections are in a region in central Europe. (cdc.gov)
  • I am interested in the biology of hard ticks and soft ticks, and in their role as vectors of tick-borne spirochetes (Borrelia) in South America. (anid.cl)
Antibodies3
  • IgM antibodies are detectable in humans approximately 2-4 weeks after the initial infection. (altmeyers.org)
  • IgM antibodies are often detectable over a longer period of time, which makes it difficult to draw conclusions about the approximate time of infection. (altmeyers.org)
  • The patterns of anti-Borrelia antibodies, in infected people, show a high degree of variability, which makes their assessment difficult. (altmeyers.org)
Clinical2
Prevalence3
  • However, the prevalence of infection differed significantly among areas. (archive.org)
  • Infection prevalence varied from 9% to 40% in nymphs and from 22% to 47% in adults. (archive.org)
  • There was no correlation between nymphal density and infection prevalence as well as between adult density and infection prevalence, but there was a correlation between density of ticks and density of infected ticks. (archive.org)
Humans1
  • Since some symbionts, such as R. helvetica can cause disease in humans, we propose that public health investigations consider geographical differences in its infection rates. (biomedcentral.com)
Complex1
Study1
  • The infection rates of all vertically transmitted symbionts differed between the study sites, and none of the symbionts was present in all tested ticks suggesting a facultative association with I. ricinus . (biomedcentral.com)
Rates1
  • This suggests that geography-related factors affect the infection rates of vertically transmitted symbionts in I. ricinus . (biomedcentral.com)
Weeks1
  • They reach their maximum about 6-8 weeks after infection. (altmeyers.org)
Sensu lato10
Genospecies1
  • [ 1 ] Most importantly, some manifestations of the disease are associated exclusively with specific Borrelia genospecies. (medscape.com)
Polymerase chain re1
Ticks2
  • closely related to Borrelia valaisiana in Ixodes ticks removed from dogs and cats in Japan. (nih.gov)
  • Lyme disease, or 'lyme borreliosis', is one of multiple infections which can be transmitted by ticks, many of which by themselves or collectively together as 'co-infections', can result in a staggering and far-reaching set of chronic symptoms, called ' Multiple Systemic Infectious Disease Syndrome' (MSIDS). (nenaturalmedicine.com)
Genetic1
Strains1
Strain1
  • Borrelia are microaerophilic and slow-growing-the primary reason for the long delays when diagnosing Lyme disease have been found to have greater strain diversity than previously estimated. (wikipedia.org)
Isolates1
  • The association of both monoclonal antibody A116k and primers Bval 1F and Bval 1R allows to specific identification of the B. valaisiana isolates belonging to subgroup 1. (biomedcentral.com)
Babesia1
  • The first case of human babesiosis in Denmark was reported in 2013 [ 7 ] and represented an imported case of Babesia microti infection from the United States. (biomedcentral.com)
Lyme borreliosis1
Ixodes1
  • He had been bitten by an Ixodes persulcatus tick in which the DNA of Borrelia valaisiana was detected. (nih.gov)
Rickettsia1
  • Over 90% of human flea-borne rickettsioses cases in California are reported from suburban communities of Los Angeles and Orange counties and are presumed to be associated with either Rickettsia typhi or Rickettsia felis infection. (bioone.org)
Patients2
  • 8 , 9 The review panel held a hearing in July 2009 that was broadcast live over the internet and featured more than 300 peer-reviewed articles and 1600 pages of analysis supporting the concept of persistent infection despite short-course antibiotic therapy of 2 to 4 weeks in patients with persistent Lyme disease symptoms. (anti-agingfirewalls.com)
  • I know âbecause I've seen it both in myself and in my patients â that a holistic approach which takes into account not only the infections in your body but what you're eating, how much you're sleeping, how much water you're drinking, what you're doing about past trauma, whether you are surrounding yourself with loving, supportive people â all those things matter and are within your control. (lymetalk.net)
Chronic1
Multiple1
  • We developed a workflow pipeline for the de novo genome assembly for Borrelia using several types of sequence data and incorporating multiple assemblers to recover the complete genome including both circular and linear plasmid sequences. (biomedcentral.com)
Disease2
  • Serologic examination detected antibodies to Lyme disease Borrelia. (nih.gov)
  • The expansion of Lyme disease's endemic range, as well as the difficulty of diagnosing infection and the disease's steady increase in incidence in the face of proven preventative measures, make the pursuit of a Lyme disease vaccine a worthwhile endeavor. (medscape.com)
Specific1
  • In the same way, we have designed primers specific to ospA gene of B. valaisiana . (biomedcentral.com)
High3
  • The de novo assembly of a complete Borrelia genome is challenging due to the high levels of complexity, represented by a high number of circular and linear plasmids that are dynamic, showing mosaic structure and sequence homology. (biomedcentral.com)
  • Here, using recently developed high-fidelity (HiFi) PacBio sequencing, we explored strategies to obtain gap-free, complete and high quality Borrelia genome assemblies. (biomedcentral.com)
  • Despite the latest available technologies, stand-alone sequencing and assembly methods are insufficient for the generation of complete and high quality Borrelia genome assemblies. (biomedcentral.com)
Cases1
  • Evidence of only limited numbers of R. typhi -infected cat fleas in the environment may indicate a very rare infection and explain why so few cases of flea-borne rickettsioses are reported each year in southern California relative to the population. (bioone.org)
Levels1
  • The detailed data of the infection levels at each location could be useful in assessing the risk of pathogen acquisition following a tick bite. (springer.com)