Vaccine drug stability. Medical search. Frequent questions

Additionally, the sudden outbreak of the COVID-19 pandemic and the success of Moderna's and Pfizer-BioNTech's COVID-19 vaccines are poised to create new growth opportunities in the mRNA vaccine market in the near future. (businesswire.com)
These clinical considerations provide information to healthcare professionals and public health officials on use of COVID-19 vaccines. (cdc.gov)
The 2023-2024 formulation for all COVID-19 vaccines licensed or authorized in the United States (Moderna, Novavax, and Pfizer-BioNTech) has been updated to a monovalent vaccine based on the Omicron XBB.1.5 sublineage of SARS-CoV-2. (cdc.gov)
The need for business As government officials step up their immunization campaigns, there will likely be a rise in COVID-19 vaccines that are stable and can be kept for a long time. (precedenceresearch.com)
Fragile mRNA molecules used in COVID-19 vaccines can't get into cells on their own. (acs.org)
The success of these COVID-19 vaccines is remarkable and was far from guaranteed. (acs.org)
We strongly believe there is a compelling need for next-generation COVID-19 vaccines and are rapidly advancing our development program for AdCOVID to meet this demand," said Dr. Vipin K. Garg, President and CEO of Altimmune. (yahoo.com)
On the other hand, potential COVID-19 vaccines may provide an opportunity to strengthen national immunization programmes. (who.int)

This method was also tested with actual biologics payloads, including ovalbumin, a protein in egg whites commonly used as a model antigen to trigger an immune response, and the trivalent inactivated polio vaccine (IPV). (drugdiscoverynews.com)
Our Biologics Guide highlights tools and techniques for characterizing biologics and complex drugs. (wyatt.com)
Temperature sensitive drug products, such as biologics or insulin, often require cold storage. (westpharma.com)
Drug products such as biologics, vaccines and products whose chemical and physio-chemical stability depends on temperature put an added emphasis on pharmaceutical manufacturers to ensure proper handling, storage, transportation and dispensing. (westpharma.com)
A tremendous rise in the biologics market has driven significant interest in their discovery and in using novel drug delivery systems to enable drug delivery via different routes. (aaps.org)
This theme focuses on different strategies and challenges involved in the design of drug delivery systems, the delivery of biologics, and manufacturing challenges in the development of novel drug delivery systems. (aaps.org)
With the rise of biologics and next-generation vaccines (mRNA, adenoviral vectors. (aptar.com)
Enabling drug packaging in extreme conditions will support the development of increasingly sensitive drug products such as mRNA vaccines, complex biologics and biotech drugs. (aptar.com)
Biologics, including monoclonal antibodies, recombinant proteins, and vaccines, are in high demand owing to their remarkable specificity and effectiveness. (reportsanddata.com)
THE fasted growing segment in the pharmaceutical industry is biologics (protein drugs), especially mAbs. (europeanpharmaceuticalreview.com)

Delivery of difficult to formulate therapeutics, including proteins, peptides, vaccines and genetic material has been established using microneedles. (ias.ac.in)
Through our mechanistic findings related to polymer/drug behavior in other projects, we have devised two new approaches for facile microencapsulation of biomacromolecular therapeutics with strong advantages over existing methods. (umich.edu)
Learn how Wyatt Technology's products support research and development of modern therapeutics-including biological and non-biological complex drugs. (wyatt.com)
Building on the response to recent outbreaks of Ebola virus disease, SARS-CoV and MERS-CoV, the R&D Blueprint has facilitated a coordinated and accelerated response to research into diagnostics, vaccines and therapeutics for the novel disease. (who.int)
As the field of targeted drug delivery advances with new modalities such as lipid nanoparticles, cell therapies, and gene therapeutics, science is also gaining ground in the design of protein therapeutics tailored to deliver to specific tissues (examples: eye, tumor, or brain) and methods for bioanalysis. (aaps.org)
The field of analytical platform technology is racing to keep pace with the emergence of new modalities such as oligonucleotides and cell and gene therapies, as well as the increasing need for more informative analytical evaluation of traditional therapeutics such as monoclonal antibodies and antibody drug conjugates. (aaps.org)
The National Institutes of Health (NIH), the US's medical research agency, selected Exothera S.A., a full-service Contract Development and Manufacturing Organization (CDMO) specialized in gene therapy, vaccines, oncolytic viruses, and nucleic acid-based therapeutics, to develop the manufacturing process for NIH's intranasal vaccine against SARS-CoV-2. (technologynetworks.com)
In this next phase, we will expand our roadmap to include novel technologies and applications for emerging classes of therapeutics and vaccines, allowing the pharmaceutical industry to deploy effective medicines and vaccines more efficiently and rapidly. (purdue.edu)

mRNA vaccines induce the production of proteins that trigger an immune response in the human body. (businesswire.com)
This can damage the drugs within, which usually contain proteins or nucleic acids. (studyfinds.org)
Nomura is a world-renowned expert in chemical biology whose research focuses on developing drugs that target proteins previously considered "undruggable" - proteins known to drive disease, but which do not contain the type of obvious binding pockets required for traditional drug discovery approaches. (berkeley.edu)
Usually, human proteins remain stable up to about 40°C. Higher temperatures are of course not found in the body, but the stability of C4BP has a completely different purpose: "As is the case with all components of the complement system, the C4b binding protein is present in blood plasma. (nanowerk.com)
Both the production of recombinant proteins and the development of in vitro diagnostic assays for drug research heavily rely on the utilization of expression vectors. (reportsanddata.com)
Plasmid vectors are commonly used in gene therapy, vaccine development, and the production of recombinant proteins. (reportsanddata.com)
This stability enables the proteins to withstand extreme conditions in which ordinary proteins do not survive. (sciencedaily.com)

See Appendix A for recommendations for people who received COVID-19 vaccine outside the United States. (cdc.gov)

mRNA vaccines, including those encoding TAA (tumor-associated antigens), TSA (tumor-specific antigens), and related cytokines, play a significant role in cancer vaccine development. (businesswire.com)
The Schwendeman laboratories involves the use of mechanistic approaches to control the release of biomacromolecular drugs, vaccine antigens, and challenging small molecules (e.g., hydrophobic anticancer drugs) from biodegradable polymers. (umich.edu)

This is a platform that can be broadly applicable to all types of vaccines, including recombinant protein-based vaccines, DNA-based vaccines, even RNA-based vaccines," says senior study author Dr. Ana Jaklenec in a media release . (studyfinds.org)
The Nuvaxovid™ (NVX-CoV2373) Novavax vaccine is a recombinant spike (S) protein nanoparticle vaccine combined with the Matrix-M adjuvant. (medscimonit.com)
Nuvaxovid™ (NVX-CoV2373) (Novavax Inc., Gaithersburg, MD, USA) is the first recombinant protein-based vaccine to SARS-CoV-2, combined with an adjuvant, to receive regulatory approval, currently in Great Britain and the European Union (EU) [10,11]. (medscimonit.com)
Preclinical studies have shown that the NVX-CoV2373 SARS-CoV-2 vaccine consists of full-length, stabilized, prefusion, recombinant S protein components combined with a saponin-based adjuvant, Matrix-M [12]. (medscimonit.com)
found that recombinant SARS spike-protein-based vaccines not only failed to provide protection from SARS-CoV infection, but also that the mice experienced increased immunopathology with eosinophilic infiltrates in their lungs. (coldfury.com)
The ACIP's 2014 Adult Immunization Schedule for influenza vaccine includes information about the recombinant influenza vaccine and addresses the use of this vaccine and the inactivated influenza vaccine in patients with egg allergy. (medscape.com)

Roche, Indianapolis, IN, USA) is destined to be one of the few branded drugs to develop instant street recognition because of its status as 1 of only 2 licensed drugs shown to be active against the influenza A pandemic (H1N1) 2009 virus. (cdc.gov)
Tamiflu is the major drug stockpiled by governments around the world in preparedness against an influenza pandemic. (cdc.gov)
Using lipid-encapsulated or naked forms of sequence-optimized mRNA, mRNA vaccines have produced potent immunity against infectious disease targets in animal models of influenza virus, Zika virus, rabies virus, and others, particularly in recent years. (businesswire.com)
Whether it is an influenza pandemic or outbreak such as the recent Ebola crisis in Africa or diseases such as Malaria or Severe Acute Respiratory Syndrome ( SARS ), the need for cheaper, effective vaccines is on the rise. (uk-cpi.com)
Influenza A and B vaccine is administered each year before flu season. (medscape.com)
Traditionally, the vaccine was trivalent (ie, designed to provide protection against three viral subtypes, generally an A-H1, an A-H3, and a B). The first quadrivalent vaccines, which provide coverage against an additional influenza B subtype, were approved in 2012 and were made available for the 2013-2014 flu season. (medscape.com)
5, 6] For the 2021-2022 influenza season, all flu vaccines are expected to be quadrivalent. (medscape.com)
The FDA has approved a vaccine for H5N1 influenza. (medscape.com)
In the Northern Hemisphere, all persons aged 6 months or older should receive influenza vaccine annually by the end of October, if possible. (medscape.com)
Influenza vaccination should not be delayed to procure a specific vaccine preparation if an appropriate one is already available. (medscape.com)
Those with a history of egg allergy who have experienced only hives after exposure to egg should receive influenza vaccine. (medscape.com)
The new lineage was "no longer well controlled" by the vaccines that had been developed to protect against the earlier lineage, he said, and roughly 10% of isolates now showed markers of resistance to the main class of anti-influenza drugs -- the neuraminidase inhibitors. (medpagetoday.com)
Last year when federal health officials declared a pandemic H1N1 "swine flu" national emergency, drug companies put a full court press on the FDA to fast track licensure of highly reactive oil based squalene adjuvants and the use of new technology, like insect cells, to make pandemic influenza vaccines. (ageofautism.com)
FluMist vaccine for influenza is being promoted with big $$$ advertising this year, and at nearly 70 $ per "shot" the flu promises to be hot business. (newmediaexplorer.org)
MedImmune, the manufacturer of FluMist, recently announced that it signed an agreement that makes FluMist, the new intranasal influenza vaccine, readily available to people as they shop at Wal-Mart, the worlds biggest retailer. (newmediaexplorer.org)
FluMist contains live (attenuated) influenza viruses that replicate in the nasopharynx of the vaccine recipient. (newmediaexplorer.org)
NIH's candidate is based on the Adenovirus 4 backbone, largely used as a vector candidate in HIV and influenza vaccine clinical trials, produced in an A549 cell line. (technologynetworks.com)
Influenza vaccine provides reasonable protection against immunized strains. (medscape.com)
Historically, influenza vaccine has had 50%-60% efficacy against infection with influenza A viruses and 70% efficacy against influenza B viruses. (medscape.com)
the vaccine had 47% efficacy against the predominant influenza A H3N2 subtype and 67% efficacy against influenza B virus infections. (medscape.com)
The quadrivalent influenza vaccines contain an additional B strain, B/Brisbane/60/2008-like (B/Victoria lineage), in addition to the 3 viral strains listed above. (medscape.com)
Influenza vaccine is also available as a nasal spray (FluMist) that contains live, attenuated influenza virus (LAIV). (medscape.com)

Ltd. (RSA), to investigate EmzaloidTM Technology as a mucosal vaccine delivery system. (port.ac.uk)
Mucosal vaccine delivery. (port.ac.uk)

The Pfizer-BioNTech Comirnaty ® Omicron XBB.1.5 subvariant, monovalent COVID-19 vaccine is approved for people who are 6 months of age and older. (canada.ca)
The safety and effectiveness of the Pfizer-BioNTech Comirnaty ® Omicron XBB.1.5 subvariant, monovalent COVID-19 vaccine is based on studies of Comirnaty ® (Original, Original/Omicron BA.4/BA.5). (canada.ca)

Principles related to drug preparation, route of administration, site-specific targeting, metabolism, and toxicity are used to optimize efficacy and safety, and to improve patient convenience and compliance. (wikipedia.org)
Global mRNA vaccine market is poised to grow at an impressive rate to 2028 on account of the various benefits of mRNA vaccine over DNA vaccine in terms of production, safety, efficacy, and distribution, among others. (businesswire.com)
Thanks to decades of scientific perseverance, billions of dollars of investment in the technology, and previous work on coronaviruses , the vaccine makers were able to design their vaccines and prove their safety and efficacy in under a year. (acs.org)
As noted previously , certain drugs require cold storage in order to maintain efficacy for delivery to patients. (westpharma.com)
In the event of an emergency, such mapping can help to determine the time required for conditions to return to the specific parameters required by the drug, which in turn can help determine if the product has exceeded is temperature excursion limits and thus ensure its efficacy has been maintained. (westpharma.com)
They are now seeking to patent the concept of using the mutant virus as a vaccine candidate for HMPV as it showed efficacy in protecting rats against HMPV infection. (drugtargetreview.com)
So, mutating the virus enhances vaccine efficacy," said Jianrong Li, senior author of the study and a professor of virology in The Ohio State University Department of Veterinary Biosciences and member of Ohio State's Infectious Diseases Institute, US. (drugtargetreview.com)
Vaccine efficacy against laboratory-confirmed symptomatic COVID-19 was estimated to be 78% in adults 18-59 years of age. (who.int)
Lack of data prevented estimating the efficacy of the vaccine in individuals 60 years of age and older and with comorbidities. (who.int)
Maintaining container closure integrity is essential for injectable packaging to ensure drug safety, efficacy, shelf life, regulatory compliance, and quality. (aptar.com)

The results of the first study to evaluate the stability of Trivalent Inactivated Poliovirus Vaccine (tIPV) formulated in desiccated liposomes (QuIcksome tm ) has yielded promising results. (pharmacyupdate.online)
The trivalent IPV stability evaluation was conducted to assess the preservation application of MVMD's Quicksome™ technology after five days exposure to 40°C. Trivalent IPV comprises three serotypes of inactivated polioviruses. (pharmacyupdate.online)

The development of vaccines is evolving thanks to these mRNA vaccines, supporting the next generation of vaccination. (businesswire.com)
Ontario will lift the proof of vaccination requirements for restaurants, gyms and all indoor settings on Tuesday, meaning patrons won't be required to have received two doses of the COVID-19 vaccine to enter. (ctvnews.ca)
The development, clinical evaluation, regulatory approvals, and vaccination programs for messenger RNA (mRNA) and viral vector-based vaccines to SARS-CoV-2 have rapidly progressed during the past two years [1,2]. (medscimonit.com)
Emergency use authorization (EUA) and full regulatory approvals for novel vaccines in 2020 and 2021 resulted in global vaccination programs that have reduced the severity of COVID-19, hospitalizations, and patient mortality [3,4]. (medscimonit.com)
As a manufacturer of environmental and refrigerated storage units the company is also well-positioned to put in place the facilities that will be needed at the point of vaccine distribution, at each vaccination centre. (sourcebioscience.com)
Vaccine stability is critical for efficient vaccine deployment and AdCOVID is expected to be shipped without cold chain and permit common refrigerated storage conditions at community-based vaccination centers without the need for specialized freezer storage. (yahoo.com)
Guidance added to COVID-19 vaccination schedules for correct dosage and administration of updated (2023-2024 Formula) Moderna COVID-19 Vaccine in children ages 6 months-11 years. (cdc.gov)
Prof. Junginger's laboratory was world renowned for the work done in the delivery of peptide drugs with various mucosal absorption enhancers as well as mucosal vaccination. (port.ac.uk)
Further, intranasal vaccines are a potentially valuable alternative to injected vaccines as no specific medical training is required to perform the vaccination, similar to the oral drops given globally to prevent polio. (technologynetworks.com)

I'm a co-lead of the ACIP COVID-19 Team Vaccine Workgroup and today I'll be focusing on the discussion that led to the new recommendation for an additional dose of mRNA COVID-19 vaccine for immunocompromised people. (cdc.gov)
The intervention that we're focused on is an additional dose of mRNA COVID-19 vaccine, an additional dose of Pfizer vaccine or Moderna vaccine after an initial two-dose primary series of an mRNA vaccine in immunocompromised people. (cdc.gov)
The additional dose of mRNA COVID-19 vaccine should be administered at least 28 days after completion of the primary mRNA series. (cdc.gov)

Print advertisements and magazine articles apparently will use scare tactics similar to those that were used while promoting the smallpox vaccine which warned of the high possibility of a "bioterror attack using the flu virus. (newmediaexplorer.org)

On December 20, 2021, the European Commission of the European Union (EU) granted conditional marketing authorization for the Nuvaxovid™ (NVX-CoV2373) Novavax vaccine, following recommendations from the European Medicines Agency (EMA). (medscimonit.com)
We are excited about the potential of our AdCOVID vaccine candidate and are actively focused on expanding our network of strategic manufacturing partners to ensure Altimmune's commercial readiness to supply vaccine in 2021 should our clinical data support this advancement," said Dr. Vyjoo Krishnan, Ph.D., Vice President of Product Development for Altimmune. (yahoo.com)
Our agreement with Lonza expands on our current clinical and commercial manufacturing strategy for AdCOVID, aligning us with leaders in vaccine manufacturing and positioning Altimmune for commercial-readiness in 2021. (yahoo.com)
In addition, the COVID-19 Global Vaccine Access (COVAX) Facility was established under the leadership of Gavi, the Vaccine Alliance, with the aim of having 2 billion doses of vaccine distributed equitably across the world by the end of 2021. (who.int)

The stability of Dryvax vaccine was examined to determine whether diluted vaccine could be used over an extended period, thereby increasing the number of available doses. (emmes.com)
Ontario launched the vaccine passport system last September, requiring eligible residents to have two doses of the COVID-19 vaccine to enter non-essential businesses. (ctvnews.ca)
Ottawa Public Health says 63 per cent of Ottawa residents aged 18 and older have received three doses of the COVID-19 vaccine. (ctvnews.ca)
CAMBRIDGE, Mass. - A one-jab, self-boosting vaccine that provides patients with several doses at different times is currently under development. (studyfinds.org)
A team from the Massachusetts Institute of Technology (MIT) recently shared news of a 3D fabrication method capable of designing novel drug-carrying particles that can enable multiple doses of a compound to be administered over time from a single injection. (drugdiscoverynews.com)
This past spring, the FDA took a hands-off approach to Merck's admission that DNA from a lethal pig virus is contaminating doses of RotaTeq vaccine being swallowed by millions of newborn babies. (ageofautism.com)
2 doses for a primary series in ages 5 years and older or 3 smaller doses for a primary series in ages 6 months to under 5 years, except for the Omicron XBB.1.5 subvariant vaccine. (canada.ca)
8. Immunosuppressive doses of systemic medications, such as steroids or absorbed topical steroids (doses >10 mg/day prednisone or equivalent) within 2 weeks before study drug administration. (who.int)

A more recent study found the median cost of bringing a new drug to market was $985 million in 2020, but did not look at the cost of developing drug delivery systems. (wikipedia.org)
MHRA grants temporary authorisation for Pfizer and BioNTech COVID-19 mRNA vaccine' Pfizer news release, 2nd Dec 2020. (sourcebioscience.com)
GAITHERSBURG, Md. and BASEL, Switzerland, Nov. 10, 2020 (GLOBE NEWSWIRE) -- Altimmune, Inc. (Nasdaq: ALT), a clinical-stage biopharmaceutical company, today announced that it entered into an agreement with Lonza for the manufacturing of AdCOVID ™ , Altimmune's next-generation, single-dose intranasal vaccine candidate for COVID-19. (yahoo.com)
The Regional Committee is invited to endorse the proposed regional strategy to improve access to medicines and vaccines in the Eastern Mediterranean, 2020-2030. (who.int)

A potential target of vaccine therapies for all three known β-CoVs is the Spike (S) glycoprotein. (frontiersin.org)
It also opens the door to delivering a range of other therapies including cancer drugs, hormone treatments, and other medications. (studyfinds.org)
A way of introduction for those of you new to Maravai, we provide reagents and services focused on high growth markets and cell and gene therapies, vaccines and biologic drug manufacturing. (seekingalpha.com)
Improved surveillance, epidemiological research and development of new therapies and vaccines are important, and the momentum of recent gains in terms of better understanding of disease patterns should be maintained to enable the global community to answer the remaining questions about this disease. (who.int)

Since the approval of the first controlled-release formulation in the 1950s, research into new delivery systems has been progressing, as opposed to new drug development which has been declining. (wikipedia.org)
Drug substance formulation development - liquid/frozen liquid and lyophilised. (uk-cpi.com)
This is achieved by taking novel antigen candidates, formulating them within liposomes (tiny bubbles comprised of cell material), freeze drying the formulation to remove all the water content to ensure stability and suspending a drug candidate before reconstitution in an oil formulation for delivery. (equities.com)
A formulation consisting of IPV and other substances was loaded into cups, which were then sealed to assess if the heat of the sealing process affected stability. (drugdiscoverynews.com)
Differential scanning calorimetry (DSC) has been one of the most widely used techniques to characterise the temperature stability of monoclonal antibodies (mAbs) and provide important information in formulation optimisation. (europeanpharmaceuticalreview.com)

According to Ana Jaklenec, a research scientist at MIT's Koch Institute for Integrative Cancer Research and another senior author of the Science paper, "This new method called SEAL (StampEd Assembly of polymer Layers) can be used with any thermoplastic material and allows for fabrication of microstructures with complex geometries that could have broad applications, including injectable pulsatile drug delivery, pH sensors and 3D microfluidic devices. (drugdiscoverynews.com)
We apply our mechanistic studies toward development of novel injectable depots, particularly for biomacromolecular drugs. (umich.edu)
Injectable drugs are administered directly into the body, making their safety of utmost importance. (aptar.com)
Injectable drugs are formulated to be effective under specific conditions, and any loss or alteration of the drug due to a compromised container closure system may compromise its therapeutic effectiveness. (aptar.com)
Injectable drugs often have a defined shelf life, which is determined by their stability over time. (aptar.com)
Injectable vaccine, which contains inactivated virus, is available in a variety of dosage forms. (medscape.com)

Healthcare providers who administer the Moderna COVID-19 Vaccine (2023-2024 Formula) to individuals ages 6 months through 11 years should ensure the correct volume of the vaccine (0.25 mL) is withdrawn from the vial and administered to the recipient. (cdc.gov)
All people ages 65 years and older should receive 1 additional dose of any updated (2023-2024 Formula) COVID-19 vaccine (i.e. (cdc.gov)
These vaccines are hereafter referred to as updated (2023-2024 Formula) Moderna COVID-19 Vaccine. (cdc.gov)
These vaccines are hereafter referred to as updated (2023-2024 Formula) Pfizer-BioNTech COVID-19 Vaccine. (cdc.gov)
The global pharmaceutical stability and storage services industry revenue will gain around USD 5.4 billion by 2032 from USD 3.01 billion in 2022 and is growing at a remarkable CAGR of 6.02% from 2023 to 2032. (precedenceresearch.com)

This year, hundreds of millions of people will receive shots of the Pfizer-BioNTech or Moderna vaccines for COVID-19 . (acs.org)
BioNTech COVID-19 vaccine, ages 12 and older, and Moderna COVID-19 vaccine, ages 18 and older. (cdc.gov)

Usually, patients receive the polio vaccine in a series of two to four separate injections. (studyfinds.org)

There are several advantages of using nanotechnology for drug delivery, including precise targeting of specific cells, increased drug potency, and lowered toxicity to the cells that are targeted. (wikipedia.org)
Novartis is now working with Nomura and Professor Dean Toste of UCB's Department of Chemistry to test the inhibitors for their anti-viral activity in cell lines and animal models and to optimize their potency and metabolic stability with the goal of producing an oral pan-coronavirus inhibitor. (berkeley.edu)

Targeted drug delivery is the delivery of a drug to its target site without having an effect on other tissues. (wikipedia.org)
Interest in targeted drug delivery has grown drastically due to its potential implications in the treatment of cancers and other chronic diseases. (wikipedia.org)

With the ability to characterize all 24 represented serotypes in both pneumococcal conjugate and pneumococcal polysaccharide vaccine samples in less than 30 minutes, the test offers substantial time, throughput, and labor savings over the singleplex technologies. (indevr.com)
Additional changes have been made for Td/Tdap vaccine, varicella vaccine, human papillomavirus vaccine, zoster vaccine, 13-valent pneumococcal conjugate and 23-valent pneumococcal polysaccharide vaccines, meningococcal vaccine, and Haemophilus influenzae type B vaccine. (medscape.com)

Therefore, it is surprising that discovery and development programs were not established earlier in the COVID-19 pandemic to produce more conventional protein-based vaccines. (medscimonit.com)
In SARS, a type of "priming" of the immune system was observed during animal studies of SARS spike protein-based vaccines leading to increased morbidity and mortality in vaccinated animals who were subsequently exposed to wild SARS virus. (coldfury.com)

We proved a concept that these mutant viruses are improved vaccine candidates for HMPV. (drugtargetreview.com)

A true platform technology for cancer and infectious disease vaccine candidates, DepoVax utilizes a 100% oil-based, "no release" depot delivery system. (equities.com)
Alberto Santagostino, SVP, Head of Cell and Gene Technologies for Lonza, commented, "We are deeply committed to fighting this global pandemic and deploying our expertise and resources to help vaccine developers like Altimmune meet commercial manufacturing requirements for novel and promising vaccine candidates. (yahoo.com)
The purpose of this Funding Opportunity Announcement (FOA) is to support translation of advanced HIV-1 vaccine candidates from pre-clinical studies through different phases of process and product development, Current Good Manufacturing Practice (CGMP) manufacturing and regulatory filing to the point of clinical testing. (cdc.gov)

At the heart of the VaxArray Pneumococcal Assay Kit are simple microarrays, each of which contains 24 serotype-specific monoclonal antibodies for high priority pneumococcal capsular polysaccharide serotypes present in a variety of both on-market and in-development pneumococcal vaccines. (indevr.com)
Can DSC calorimetry gauge long‑term stability for monoclonal antibodies? (europeanpharmaceuticalreview.com)
Can calorimetry provide accurate estimates of long‑term stability for monoclonal antibodies? (europeanpharmaceuticalreview.com)

The goal of the present investigation is to examine the effects of missense mutations in the MERS-CoV S protein on protein stability and binding affinity with DPP4 to provide insight that is useful in developing vaccines to prevent coronavirus infection. (frontiersin.org)
Accordingly, the United States is enacting the Coronavirus Support Relief Economic Stability Act, implementing large-scale financial support, and investing large-scale financing in the R&D field of infectious disease. (kisti.re.kr)
Live, replicating, intranasal vaccines have the promise of effectively interrupting transmission of coronavirus, COVID-19 by inducing the development of immunity in the respiratory tract. (technologynetworks.com)
RÉSUMÉ Une analyse documentaire des informations publiques disponibles a été entreprise afin de passer en revue les connaissances et les lacunes actuelles sur le coronavirus du syndrome respiratoire du Moyen-Orient (MERS-CoV), notamment sur son origine, la transmission, les mesures de lutte efficaces et la prise en charge. (who.int)

It further shines a spotlight on companies like Halifax, Canada-based Immunovaccine (IMV:CA)(IMMVF) and the fact that investors and scientists alike are looking ahead to clinical data this quarter from Immunovaccine's DepoVax cancer vaccine platform. (equities.com)

Novavax COVID-19 Vaccine, Adjuvanted (hereafter referred to as Novavax COVID-19 Vaccine) is authorized for people ages 12 years and older. (cdc.gov)

Other factors that have potentially influenced the increase in drug delivery system development may include the increasing prevalence of both chronic and infectious diseases, as well as a general increased understanding of the pharmacology, pharmacokinetics, and pharmacodynamics of many drugs. (wikipedia.org)
This has prompted numerous biotechnology and pharmaceutical companies, along with academic and research institutions, to engage in research, development, and clinical trials for various mRNA vaccines. (businesswire.com)
Industry expansion is expected to be bolstered by increased investments in cutting-edge and effective mRNA vaccine development. (businesswire.com)
Thanks to advances in medicine, we can now use viruses to treat disease , and it's this area of vaccine development where CPI can help. (uk-cpi.com)
We are working with companies to help treat disease through the development of innovative viral vectors and vaccines. (uk-cpi.com)
For more information on vaccine development at CPI or to speak to one of our experts please don't hesitate to get in touch . (uk-cpi.com)
The number of drugs will likely grow due to the increasing research and development costs. (precedenceresearch.com)
Another element influencing industry development is the requirement for stability testing before each step of a clinical trial can be approved. (precedenceresearch.com)
Also, the vaccine is stable and has a shelf life of 9 months when stored at standard refrigerated temperatures of between 2-8°C. This Editorial aims to present an update on the first approval of a protein-based adjuvanted vaccine for SARS-CoV-2, Nuvaxovid (NVX-CoV2373) from Novavax, and why it is such a significant development at this time. (medscimonit.com)
Perhaps nothing exemplifies the value of potential RNA vaccines more than Eli Lilly ( LLY ) recently agreeing to pay up to $1.8 billion to work with the mRNA (messenger RNA) experts at CureVac AG on a portfolio of five mRNA cancer vaccines in development. (equities.com)
InDevR can develop a custom kit that improves your vaccine development or serological testing needs. (indevr.com)
The current global COVID-19 public health emergency underscores the need to accelerate the development of COVID-19 candidate vaccines. (who.int)
The vaccine development is carefully reviewed and discussed in order to assess their value in protecting against COVID-19 and a potential recommendation of use based on a careful benefit - risk approach. (who.int)
The spike protein of SARS-CoV--a target for vaccine and therapeutic development. (who.int)
This track explores how Artificial Intelligence/Machine Learning (AI/ML) and big data are transforming the landscape of drug development and reducing discovery time and cost. (aaps.org)
Germany is promoting digital transformation in existing industries through key industrial investments, and expanding the budget for R&D (vaccines, drug development, etc.) related to Corona 19. (kisti.re.kr)
The project includes tech transfer, stability study, CMC study and AS development and QC testing, before initiating manufacturing of the drug product in its GMP facility in Jumet, Belgium - one of the biggest dedicated viral vectors plants in Europe that can accommodate projects from development to commercial manufacturing scale. (technologynetworks.com)
The 2030 Agenda for Sustainable Development identified access to safe, effective, quality and affordable essential medicines and vaccines as central to the achievement of universal health coverage, in target 3.8 of the Sustainable Development Goals (SDGs). (who.int)
It advances eight strategic objectives related to: updating and implementing national policies for medicines and vaccines ecuring adequate and sustainable funding nsuring the availability of medicines and vaccines at fair and affordable prices stablishing efficient supply systems trengthening national regulatory authorities ensuring appropriate use of medicines romoting research and development as well as local production establishing a strong partnership framework. (who.int)
Using helium-leak and headspace laser analysis, Aptar Pharma has demonstrated the ability of PremiumCoat® vial stoppers to maintain Container Closure Integrity down to -80°C. This feature, combined with the ETFE film-coating that protects drugs from Extractable and Leachables, makes the PremiumCoat® platform an ideal solution for accelerating your sensitive drug development. (aptar.com)
When looking towards the future, Prof. Landau clarifies that "in academia itself, it's difficult to carry out a full process of drug development due to the prohibitive cost entailed. (sciencedaily.com)
Like other arenaviruses, Lassa virus lacks a ogy and clinical presentation, treatment, prevention conventional negative-strand coding arrangement and control as well as the current theories of its patho- and the isolates of the virus differ in their genetic, genesis and efforts in vaccine development. (folkhalsomyndigheten.se)

The WHO Controlled Temperature Chain allows vaccines to be kept at temperatures outside the traditional cold chain of +2°C to +8°C for a limited period of time under monitored and controlled conditions, as appropriate to the stability of the antigen. (pharmacyupdate.online)

In addition, Wyeth, MedImmunes partner, plans a three-year, $100 million campaign to encourage use of the nasal flu vaccine among physicians. (newmediaexplorer.org)
A cause for significant concern is the vaccines most prevalent side effects: "runny nose" and "nasal congestion. (newmediaexplorer.org)

Current efforts in drug delivery are vast and include topics such as controlled-release formulations, targeted delivery, nanomedicine, drug carriers, 3D printing, and the delivery of biologic drugs. (wikipedia.org)
They found that the IPV D-antigenicity "remained statistically similar before and after the sealing process," according to the paper, and "the stability of the biologic during sealing in PLGA1 was much higher than what is typically reported for microsphere encapsulation with an emulsion-based process, likely due to the elimination of organic solvents, emulsification stressors and washing, which can lead to substantial losses. (drugdiscoverynews.com)

Through processes like codon optimization, nucleoside modification, and improved delivery methods, mRNA stability and translation efficiency can be enhanced, resulting in nucleic acid vaccines with high specificity and durable stability. (businesswire.com)

The scientific director of Ontario's COVID-19 Science Advisory Table is urging everyone to get their third dose of the COVID-19 vaccine, as Ontario prepares to scrap the vaccine passport for all non-essential settings. (ctvnews.ca)
There are still tens of thousands of older adults who are not yet maximally protected against their higher risk of hospitalization and severe illness by having a booster dose of the COVID-19 vaccine,' Dr. Vera Etches said in a statement on Feb. 14. (ctvnews.ca)
ALC-0315 is one of the components of the BNT162b2 vaccine (0.43 mg per dose). (wikipedia.org)
And at nearly $70 a dose, this will be a financial bonanza for MedImmune and Wyeth, who are expecting the vaccine to become the blockbuster new drug that will push MedImmunes revenues to more than $1billion/year. (newmediaexplorer.org)
AdCOVID is a single-dose COVID-19 vaccine candidate that has the potential to be conveniently administered via an intranasal spray. (yahoo.com)
Based on clinical experience with Altimmune's vaccine platform technology, AdCOVID is expected to provide durable immunity of up to a year or more following a single dose and to have an excellent tolerability and stability profile. (yahoo.com)
1 dose as a booster, except the Omicron XBB.1.5 subvariant vaccine. (canada.ca)
On August 12th, the FDA, or Food and Drug Administration, authorized a conditional dose for certain immunocompromised individuals. (cdc.gov)
7. Major surgery within 4 weeks before the first dose of the study drug or minor surgery within 1 week (subject must also have recovered from any surgery-related toxicities to less than CTCAE Grade 2). (who.int)

Drug delivery refers to approaches, formulations, manufacturing techniques, storage systems, and technologies involved in transporting a pharmaceutical compound to its target site to achieve a desired therapeutic effect. (wikipedia.org)
There is additional emphasis on increasing the bioavailability and duration of action of a drug to improve therapeutic outcomes. (wikipedia.org)
Furthermore, recent technological progress in translation, stability, and delivery methods has positioned messenger RNA as a promising therapeutic tool. (businesswire.com)
mRNA vaccines have paved the way for new opportunities in pharmacology and have become a significant therapeutic category. (businesswire.com)
Immunosuppressives may diminish therapeutic effects of vaccines and increase risk of adverse effects (increased risk of infection). (medscape.com)

The Pfizer-BioNTech Comirnaty ® Original and Omicron BA.4/BA.5, bivalent COVID-19 vaccine is approved as a primary series for people who are 6 months of age and older and as a booster for people who are 5 years of age and older. (canada.ca)
The Pfizer-BioNTech Comirnaty ® Original and Omicron BA.1, bivalent COVID-19 vaccine is approved as a booster for people who are 12 years of age and older. (canada.ca)
The Pfizer-BioNTech Comirnaty ® Original and Omicron BA.4/BA.5, bivalent COVID-19 vaccine was shown to increase the immune response against the Omicron BA.4/BA.5 variants. (canada.ca)

OMV are complex molecules and few data have been collected so far on their stability. (mdpi.com)
Recent technological advancements have further enhanced mRNA stability and improved cell delivery by encapsulating the molecules in lipids, which in turn boosts spike protein production and enhances the immunological response. (businesswire.com)
It has been demonstrated that testing under three environmental conditions temperature, humidity, and light has a more detrimental effect on drug molecules and goods than humidity alone. (precedenceresearch.com)
There is a constant search for newer materials, which can easily form microneedles with sufficient strength to penetrate biological barriers, can be easily manufactured, and are compatible with drug molecules and biological systems. (ias.ac.in)
We can use the oligomerisation domain as a framework, in order to decorate it with drug molecules. (nanowerk.com)

Drug delivery is aimed at altering a drug's pharmacokinetics and specificity by formulating it with different excipients, drug carriers, and medical devices. (wikipedia.org)

Ensuring the stability of vaccines is crucial to successfully performing global immunization programs. (mdpi.com)

As per clinicaltrials.gov, there are approximately 444 ongoing clinical studies related to mRNA vaccines across different regions worldwide. (businesswire.com)
The material of construction of microneedles has emerged as a critical factor influencing clinical usage, manufacture, drug loading and drug stability. (ias.ac.in)
The vaccine was shown to be immunogenic and no safety concerns have been identified in clinical studies. (who.int)
Clinical Pharmaceutics: a strong collaboration has been established with Southampton University Hospital NHS Foundation Trust (UHS) and more specifically Southampton Pharmacy Research Centre (SPRC) with a focus on chemical and physical compatibility and stability of IV administered medicines. (port.ac.uk)
The use of carbon nanotubes in drug delivery and clinical assays. (port.ac.uk)
The Food and Drug Administration (FDA) in the United States is in charge of regulating gene therapy products, including expression vectors used in clinical trials. (reportsanddata.com)
Shealy, who's the Vaccine Clinical Inquiry Management Team Lead on the Vaccine Task Force as part of CDC's COVID-19 Response. (cdc.gov)

However, the precise physicochemical profile of an ideal carrier liposome for mucosal vaccines is still widely unknown, and how different properties affect key steps in the acquisition of protective immunity remains to be elucidated. (dissertations.se)

Like humans, drug products may have specific tolerances to cold that depend upon the product. (westpharma.com)

A number of drug carriers have been studied to effectively target specific tissues, including liposomes, nanogels, and other nanotechnologies. (wikipedia.org)
The technique involves laying down a film of desiccated liposomes containing the vaccine in a vial. (pharmacyupdate.online)
Physico-chemical characterisation of structure and stability of liposomes intended for drug delivery is the central issue in this thesis. (dissertations.se)
Liposomes are attractive vaccine carriers due to their potential to act as adjuvants, and to the fact that their composition and characteristics are virtually endlessly customizable. (dissertations.se)

Intranasal vaccines are also an impactful tool for the distribution of a vaccine against SARS-CoV-2 in remote areas with the potential to slow transmission of COVID-19 in these regions. (technologynetworks.com)
In the past, intranasal vaccines have been used to fight several mucosa-entering pathogens (e.g., respiratory viruses, measles, rubella). (technologynetworks.com)

After 4 years of relative stability, the virus began to show changes during the most recent wave, including a newfound ability to escape vaccines and to resist antiviral drugs, Uyeki said. (medpagetoday.com)

[ 56 ] The quadrivalent flu vaccines have an additional B virus. (medscape.com)

MIT researchers have developed microparticles that can be tuned to deliver their payload at different time points, which could be used to create "self-boosting" vaccines. (studyfinds.org)
The researchers are now working on ways to counteract this effect and improve stability. (studyfinds.org)
Two years ago, the researchers showed they could deliver drugs that stimulate a pathway called STING. (studyfinds.org)
Microneedle-based drug delivery has attracted researchers' attention over the last decade. (ias.ac.in)
Researchers have discovered unique amyloid fibers used by the highly drug resistant Staphylococcus aureus bacterium (which causes MRSA). (sciencedaily.com)
The researchers discovered, for the first time, unique amyloid fibrils through which the pathogenic and highly drug resistant Staphylococcus aureus bacterium attacks the human cells and immune system. (sciencedaily.com)
Patients Overpay for Prescriptions 23% of the Time, Analysis Shows Researchers at the University of Southern California analyzed millions of prescriptions and concluded that close to a quarter paid copays that exceeded the cost of the drugs. (medscape.com)

A colorless oily material, it has attracted attention as a component of the SARS-CoV-2 vaccine , BNT162b2 , from BioNTech and Pfizer . (wikipedia.org)
The two vaccine components elicit both B-lymphocyte and T-lymphocyte immune responses to the S protein of SARS-CoV-2. (medscimonit.com)
The full-length S protein in this vaccine has common epitopes that could protect against all the SARS-CoV-2 viral variants. (medscimonit.com)
Although vaccine-associated adverse events associated with the mRNA vaccines for SARS-CoV-2 are extremely rare, complications such as myocarditis and vaccine-induced immune thrombotic thrombocytopenia (VITT) continue to be reported in the medical literature and popular press [6-9]. (medscimonit.com)
Once this putative vaccine target was identified, the next challenge was how to best generate an effective immune response to SARS-CoV-2. (who.int)
The battle to develop vaccines and drugs to fight the SARS-CoV-2 virus and COVID-19, the disease which it causes, has highlighted the tremendous benefits of investing in science aimed at developing innovative research platforms and tools. (berkeley.edu)
When the SARS-CoV-2 crisis hit, Nomura immediately saw the potential to apply chemoproteomics platforms to kickstart the hunt for new drugs. (berkeley.edu)
No animal testing was done with either type of SARS-CoV-2 vaccine. (coldfury.com)

DUBLIN--( BUSINESS WIRE )--The "mRNA Vaccine Market- Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028 Segmented By mRNA Type, By Application, Region and Competition" report has been added to ResearchAndMarkets.com's offering. (businesswire.com)

We wanted to understand mechanistically what's happening, and how that information can be used to help stabilize drugs and vaccines and optimize their kinetics," Dr. Jaklenec adds. (studyfinds.org)

The "vaccine" itself is an entirely new mRNA type, a significant departure from vaccines as traditionally conceived and understood. (coldfury.com)

Such drugs will inhibit the amyloid formation thereby neutralizing one of the important 'weapons' in the arsenal of this pathogenic bacterium. (sciencedaily.com)

Such a single injection approach has the potential to not only improve patient compliance but also increase cellular and humoral immune responses to the vaccine. (studyfinds.org)
During meetings of the FDA's Vaccine Advisory Committee, the National Vaccine Information Center opposed both the quick licensure of squalene adjuvants, which hyperstimulate the immune system and have been associated with autoimmunity, and the use of insect cells, which could be contaminated with insect viruses. (ageofautism.com)
Research has shown that human metapneumovirus uses RNA methylation to hide from the immune system and that knocking out this methylation creates a mutant strain which acts like a vaccine. (drugtargetreview.com)
In cotton rats the mutant HMPV functioned like a vaccine, according to the research, preventing infection and triggering both a strong innate immune response and an effective adaptive response. (drugtargetreview.com)
The data determined that the immune response to the vaccine for both age groups was comparable to the immune response of the older participants. (canada.ca)

As it became obvious that there were inadequate drug stockpiles even in affluent countries, one of our authors (A.L.W.P., who had served as a member of the UK Committee on Safety of Medicines [ 3 , 4 ]) wrote to his local member of parliament (coauthor N.P.) to suggest that the government institute a program to extend the shelf life of drug stockpiles. (cdc.gov)
On February 3, 2022, this vaccine was granted conditional marketing authorization (CMA) in Great Britain by the Medicines and Healthcare Products Regulatory Agency (MHRA) for use in individuals ≥18 years. (medscimonit.com)
Access to medicines and vaccines continues to be a challenge worldwide, mainly for low- and middle-income countries. (who.int)
Access to medicines and vaccines in the Region varies among countries, depending on their income level and allocation of domestic resources to medicine and vaccine procurement. (who.int)
COVID-19 has imposed additional barriers to access to medicines and vaccines, including the impact of lockdowns on the supply chain which led to shortages of medical products and increases in price. (who.int)
This paper presents a new regional strategy for the Eastern Mediterranean Region which has been developed to address the barriers to accessing medicines and vaccines, and to guide countries in strengthening their national health systems over the next 10 years. (who.int)
The regional strategy aims to ensure that everyone in the Eastern Mediterranean Region has access to the quality essential medicines and vaccines they need, without suffering financial hardship, by 2030. (who.int)
Regulatory authorities, such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), have stringent requirements for container closure integrity. (aptar.com)

Shelf-life extension could potentially yield significant cost savings in the event stockpiled drugs are not required for use within the typical 5-year shelf life. (cdc.gov)
Once thought to potentially have too many shortcomings, like a short half-life in vivo and stability issues, scientific progress has moved ribonucleic acid (RNA) technology to the forefront of research for new drugs and vaccines to treat an array of maladies. (equities.com)
We are very excited about this work because, for the first time, we can create a library of tiny, encased vaccine particles, each programmed to release at a precise, predictable time, so that people could potentially receive a single injection that, in effect, would have multiple boosters already built into it. (drugdiscoverynews.com)
After reading about the MedImmune-Walmart joint venture, I felt compelled to warn our patients and our internet subscribers of the potentially serious complications that may come from direct and passive exposure to this new vaccine. (newmediaexplorer.org)
It has been documented that the live viruses from the vaccine can be shed (and potentially spread into the community) from recipient children for up to 21 days,[8] and even longer from adults. (newmediaexplorer.org)

To create and verify stability-indicating techniques and carry out analysis of leachable compounds that move from pharmaceutical packaging into the product, stability testing can present significant analytical challenges. (precedenceresearch.com)
In the industry for pharmaceutical stability & preservation, North America generated the most income. (precedenceresearch.com)
Defining requirements for worldwide industry stability testing has become a recent trend in multipurpose pharmaceutical companies. (precedenceresearch.com)
Now the agency responsible for making sure pharmaceutical products do not hurt people is proposing a Rule Change to give one staff employee the sole authority to allow "exceptions or alternatives" when drug companies want to change vaccine ingredients, such as preservatives (like thimerosal) or adjuvants (like aluminum) or the amount of residual protein and antibiotics in vaccines. (ageofautism.com)
Source BioScience is a leading supplier of outsourced stability storage with an established track record of working with the NHS and top pharmaceutical companies. (sourcebioscience.com)
Medical supplies, pharmaceutical products, and vaccines need cold temperatures for storage throughout their lifecycle. (pharmaceuticalcommerce.com)
Now that we are in the middle of a pandemic, the dangers of temperature deviations for pharmaceutical products also apply to COVID-19 test kits, related medical supplies, and vaccines. (pharmaceuticalcommerce.com)
It is a critical aspect of pharmaceutical manufacturing that safeguards patient health and maintains the integrity of the drug throughout its lifecycle. (aptar.com)

For example, several types of microneedle patches have been developed for administering vaccines and other medications to reduce the risk of needlestick injury. (wikipedia.org)
This process increases the stability and shelf life of medications and eases their long-term storage and shipping. (purdue.edu)
Regulations for different vaccines vary in much the same way as medications, but every vaccine is considered a cold chain product. (pharmaceuticalcommerce.com)

These vaccines offer versatility in addressing various diseases and patients, as they can stimulate both humoral and cellular immunity. (businesswire.com)

XCH-830SD Multi-chamber Temp/RH Stability Chamber adopts quality imported components and manufacturing process, with stable and reliable performance, independent control and climatic test of three boxes and temperature and humidity control of A, B and C boxes. (thchamber.com)
A robust container closure system ensures that the drug remains stable and retains its desired characteristics throughout its designated shelf life. (aptar.com)

The global mRNA vaccine market experiences growth driven by the increasing occurrence of cancer, genetic anomalies, and viral infections. (businesswire.com)
Cell bank and virus purity, genetic stability and characterisation. (uk-cpi.com)
Rock-paper-scissors: Engineered population dynamics increase genetic stability. (cdc.gov)

Testing for stability is crucial when creating a medicinal product. (precedenceresearch.com)
Container closure integrity plays a crucial role in maintaining the drug's stability by preventing interactions with external factors such as air, moisture, or other external contaminants. (aptar.com)

For biological products in complex formulations such as vaccines, stability validation may not be cost-effective. (cdc.gov)
Controlled or modified-release formulations alter the rate and timing at which a drug is liberated, in order to produce adequate or sustained drug concentrations. (wikipedia.org)
Understanding the process of how the vaccines are released , which is what we described in this paper, has allowed us to work on formulations that address some of the instability that could be induced over time. (studyfinds.org)

Updated information for reporting adverse events to VAERS following administration of a COVID-19 vaccine. (cdc.gov)
Any breach in the container closure system could lead to microbial contamination or drug oxidation, which could cause infections or adverse reactions when injected to a patient. (aptar.com)
Participants in Rogue Herpes Vaccine Research Take Legal Action Three participants in unauthorized herpes vaccine research file a lawsuit against scientist's company, alleging adverse side effects. (medscape.com)

Despite these potential drawbacks, the use of nanotechnology in drug delivery is still a promising area for future research. (wikipedia.org)
Led by Imperial College London, the research hub is aimed at delivering high-quality vaccines at low cost to prevent outbreaks of diseases such as Zika and Ebola. (uk-cpi.com)
Our objective is to achieve full CTC compliance at 40°C for tIPV polio vaccines in a vial format that can be reconstituted at the point of administration for injection, and we are immediately commencing this work with the Food and Drug Administration (FDA) Polio Lab under our recently signed collaborative research agreement. (pharmacyupdate.online)
there are several books free to the public on it, including 'How to predict epidemics, that I wrote a number of years ago, 'Analysis of an FDA document,' several books on the entire AIDS fiasco and 228 failed vaccine campaigns, ' and Sacrifice of the Virgins,' and of course my own research on the reversals of breast cancer and melanoma. (ageofautism.com)
The research for my MSc focused on investigating the in vitro toxicity profile of N-trimethyl chitosan chloride (TMC), a mucosal absorption enhancer used in the delivery of peptide drugs. (port.ac.uk)
Upon completion of my MSc, I was awarded a prestigious Nelson Mandela Scholarship from the University of Leiden in the Netherlands allowing me to do my PhD research in the group of Prof Dr. Hans Junginger in Pharmaceutics at Leiden Amsterdam Center for Drug Research. (port.ac.uk)
The increased research activity in a range of disciplines, including as drug discovery, proteomics, genomics, and synthetic biology, is increasing the need for expression vectors in research applications. (reportsanddata.com)
FDA Launches Criminal Investigation Into Unauthorized Herpes Vaccine Research The Food and Drug Administration rarely prosecutes research violations, but its criminal division is looking into the experimental herpes vaccine research by Southern Illinois University professor William Halford. (medscape.com)
Research Misconduct Allegations Shadow New CDC Head The Trump administration yesterday announced that HIV expert Robert Redfield will lead the Centers for Disease Control and Prevention, ignoring complaints that his work on high-profile vaccine research more than 20 years ago was flawed. (medscape.com)

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Health Care1

COVID-19 Vaccines8

Biologics10

Therapeutics8

Proteins7

Received COVID-19 vaccine1

Antigens2

Recombinant6

Influenza22

Mucosal vaccine delivery2

Monovalent2

Efficacy10

Trivalent2

Vaccination9

MRNA-COVID-193

Smallpox Vaccine1

20214

Doses8

20204

Therapies4

Formulation5

Injectable6

20235

Moderna2

Receive the polio v1

Potency2

Targeted drug del2

Pneumococcal conjugate2

Protein-based vaccines2

Improved vaccine candidates1

Candidates3

Monoclonal antibodies3

Coronavirus4

Cancer vaccine1

Ages 121

Development22

Antigen1

Nasal2

Biologic2

Nucleic1

Dose9

Therapeutic5

Pfizer-BioNTech3

Molecules5

Specificity1

Immunization1

Clinical7

Liposome1

Humans1

Liposomes4

Intranasal2

Antiviral drugs1

Quadrivalent1

Researchers7

SARS-CoV8

20181

Optimize1

Traditionally1

Pathogenic1

Immune5

Medicines8

Potentially5

Pharmaceutical8

Medications3

Immunity1

Stable2

Genetic3

Crucial2

Formulations3

Adverse3

Research9