• technology
  • While the Nextera protocol may have skewed the distribution of low and high GC phage in mixed sample communities, the technology was sensitive enough to detect rare members in the mock viral community, and in some cases, complete genomes were successfully reconstructed. (udel.edu)
  • samples
  • Strikingly, coverage patterns for the single and pooled MDA samples were nearly identical, suggesting amplification biases are reproducible and likely sequence-dependent. (udel.edu)
  • databases
  • Contrary to the low frequency of chaperonin-encoding viruses in sequence databases, a surprising diversity and abundance of viral chaperonins were discovered within viromes representing a range of marine ecosystems. (udel.edu)
  • single
  • The four adapter sequences contain palindromic sequences which hybridize and cause the single strand to fold onto itself, resulting in a tight ball of DNA approximately 300 nanometers (nm) across. (wikipedia.org)