• symptoms
  • The usual symptoms are pain and swelling of the affected salivary gland, both of which get worse when salivary flow is stimulated, e.g. with the sight, thought, smell or taste of food, or with hunger or chewing. (wikipedia.org)
  • The symptoms may develop insidiously, with the diagnosis often not considered for several years, because the complaints of sicca may be otherwise attributed to medications, a dry environment, aging, or may be regarded as not of severity warranting the level of investigation necessary to establish the presence of the specific underlying autoimmune disorder. (wikipedia.org)
  • SS can damage vital organs of the body with symptoms that may plateau or worsen, or go into remission as with other autoimmune diseases. (wikipedia.org)
  • often
  • Swelling of the gland, also usually intermittent, often suddenly appearing or increasing before mealtimes, and then slowly going down (partial obstruction). (wikipedia.org)
  • hard
  • Relatively rare in occurrence, this condition is benign, but presents as hard, indurated and enlarged masses that are clinically indistinguishable from salivary gland neoplasms or tumors. (wikipedia.org)
  • Eventual periductal and interlobular (inside the gland) sclerosis (replacement of regular tissue with hard connective tissue). (wikipedia.org)
  • patients
  • In recent times, armed with a better understanding of the occurrences and observable features of this condition, surgeons are increasingly depending upon pre-operative ultrasonography along with Fine-needle aspiration cytological (FNAC) examinations to make an accurate presumptive diagnosis, and according to one estimate, about 44% of patients undergoing submandibular resection are found to have this condition. (wikipedia.org)
  • skin
  • These include tuberous sclerosis, which causes skin lesions similar to fibrofolliculomas, and Von Hippel-Lindau disease, which causes hereditary kidney cancers. (wikipedia.org)