Tyrosine kinase imatinib mesylates. Medical search. Frequent questions

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Anatomy18

Cell Line Cell Line, Tumor Cells, Cultured Tumor Cells, Cultured 3T3 Cells K562 Cells Cell Membrane Fibroblasts Philadelphia Chromosome Cell Line, Transformed Jurkat Cells COS Cells PC12 Cells HeLa Cells NIH 3T3 Cells T-Lymphocytes CHO Cells Cell Nucleus

Organisms6

Mice, Knockout Rats, Sprague-Dawley Mice, Inbred C57BL Mice, Nude Cricetinae Cercopithecus aethiops

Diseases8

Leukemia, Myelogenous, Chronic, BCR-ABL Positive Gastrointestinal Stromal Tumors Leukemia, Myeloid, Chronic-Phase Blast Crisis Cell Transformation, Neoplastic Hypereosinophilic Syndrome Philadelphia Chromosome Gastrointestinal Neoplasms

Chemicals and Drugs163

Mesylates Ergoloid Mesylates Tyrosine Palladium Benzamides Pyrimidines Piperazines Protein-Tyrosine Kinases Protein Kinase Inhibitors Receptor Protein-Tyrosine Kinases Phosphatidylinositol 3-Kinases src-Family Kinases Protein Kinases Fusion Proteins, bcr-abl Protein-Serine-Threonine Kinases Antineoplastic Agents Phosphotyrosine Protein Tyrosine Phosphatases Proto-Oncogene Proteins c-abl Calcium-Calmodulin-Dependent Protein Kinases Proto-Oncogene Proteins c-kit Proto-Oncogene Proteins Genistein Receptor, Epidermal Growth Factor Enzyme Inhibitors Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Protein Kinase C Tyrosine 3-Monooxygenase Mitogen-Activated Protein Kinase 1 Phosphoproteins p38 Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase 3 Proto-Oncogene Proteins pp60(c-src)Proto-Oncogene Proteins c-fyn Cyclic AMP-Dependent Protein Kinases Focal Adhesion Kinase 2 Intracellular Signaling Peptides and Proteins Mitogen-Activated Protein Kinase Kinases Mitogen-Activated Protein Kinases fms-Like Tyrosine Kinase 3 JNK Mitogen-Activated Protein Kinases Janus Kinase 2 Receptor, Platelet-Derived Growth Factor alpha Focal Adhesion Protein-Tyrosine Kinases Focal Adhesion Kinase 1 Tyrphostins Adaptor Proteins, Signal Transducing p21-Activated Kinases Thiazoles Quinazolines Recombinant Fusion Proteins Indoles Recombinant Proteins Isoenzymes Vanadates Extracellular Signal-Regulated MAP Kinases CDC2 Protein Kinase Receptors, Platelet-Derived Growth Factor Proto-Oncogene Proteins c-akt RNA, Messenger Quinones MAP Kinase Kinase Kinases Phosphotransferases (Alcohol Group Acceptor)Protein Tyrosine Phosphatase, Non-Receptor Type 11 Cyclin-Dependent Kinases MAP Kinase Kinase 1 Epidermal Growth Factor Ribosomal Protein S6 Kinases Lactams, Macrocyclic Creatine Kinase Proto-Oncogene Proteins c-met Benzoquinones Casein Kinase II Phospholipase C gamma Proteins Pyrroles Casein Kinases eIF-2 Kinase Receptor, Insulin MAP Kinase Kinase 4 Pyruvate Kinase Type C Phospholipases Protein Kinase C-delta Oncogene Proteins v-abl Protein Tyrosine Phosphatase, Non-Receptor Type 6 1-Phosphatidylinositol 4-Kinase Calcium Membrane Proteins TYK2 Kinase Protein Tyrosine Phosphatase, Non-Receptor Type 1 Pyridines GRB2 Adaptor Protein Thymidine Kinase Glycogen Synthase Kinase 3 DNA-Binding Proteins Isoflavones Janus Kinase 1 rho-Associated Kinases Protein Kinase C-alpha Nitriles Androstadienes Staurosporine I-kappa B Kinase Janus Kinase 3 Platelet-Derived Growth Factor CDC2-CDC28 Kinases Enzyme Precursors Serine RNA, Small Interfering Receptor, trkA Proto-Oncogene Proteins c-hck DNA Primers Aurora Kinases Receptors, Cell Surface Proto-Oncogene Proteins c-yes Morpholines Chromones Proto-Oncogene Proteins c-ret Tetradecanoylphorbol Acetate Flavonoids Ligands Diacylglycerol Kinase Receptor, erbB-2 ZAP-70 Protein-Tyrosine Kinase Carrier Proteins Shc Signaling Adaptor Proteins TOR Serine-Threonine Kinases DNA, Complementary Cell Cycle Proteins MAP Kinase Kinase 2 Oncogene Proteins Receptor, Platelet-Derived Growth Factor beta AMP-Activated Protein Kinases Trans-Activators Receptor Tyrosine Kinase-like Orphan Receptors STAT5 Transcription Factor Receptors, Growth Factor Hepatocyte Growth Factor Threonine Cytoskeletal Proteins Adenosine Triphosphate Myosin-Light-Chain Kinase Protein Kinase C-epsilon Receptor, EphA2 MAP Kinase Kinase Kinase 1 Peptides Insulin Receptor, EphB2 Cyclic AMP Phosphoserine Ribosomal Protein S6 Kinases, 90-kDa Paxillin Receptors, Eph Family Transcription Factors STAT3 Transcription Factor raf Kinases Receptor, trkB Receptors, Vascular Endothelial Growth Factor Neoplasm Proteins Phosphoprotein Phosphatases Calcium-Calmodulin-Dependent Protein Kinase Type 2 Protein Kinase C beta Proto-Oncogene Proteins c-crk

Analytical, Diagnostic and Therapeutic Techniques and Equipment15

Transfection Blotting, Western Precipitin Tests Immunoblotting Models, Biological Mutagenesis, Site-Directed Cloning, Molecular Reverse Transcriptase Polymerase Chain Reaction Immunohistochemistry Cytogenetic Analysis Treatment Outcome Models, Molecular Electrophoresis, Polyacrylamide Gel Peptide Mapping Amino Acid Substitution

Phenomena and Processes44

Amination Phosphorylation Signal Transduction MAP Kinase Signaling System Enzyme Activation Mutation Amino Acid Sequence Drug Resistance, Neoplasm Transfection src Homology Domains Protein Binding Kinetics Genes, abl Protein Structure, Tertiary Base Sequence Apoptosis Cell Division Dose-Response Relationship, Drug Binding Sites Cell Proliferation Substrate Specificity Time Factors Sequence Homology, Amino Acid Cell Survival Cell Movement Down-Regulation Gene Expression Gene Expression Regulation, Enzymologic Gene Expression Regulation Cell Adhesion Genes, src Cell Differentiation Protein Processing, Post-Translational Cell Cycle Philadelphia Chromosome Transcription, Genetic Protein Transport Up-Regulation Point Mutation Structure-Activity Relationship Gene Expression Regulation, Neoplastic Molecular Weight Drug Synergism Amino Acid Substitution

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care1

Treatment Outcome

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Mesylates Ergoloid Mesylates Amination Tyrosine Palladium Benzamides Pyrimidines Piperazines Protein-Tyrosine Kinases Protein Kinase Inhibitors Phosphorylation Receptor Protein-Tyrosine Kinases Phosphatidylinositol 3-Kinases Leukemia, Myelogenous, Chronic, BCR-ABL Positive src-Family Kinases Signal Transduction MAP Kinase Signaling System Protein Kinases Fusion Proteins, bcr-abl Protein-Serine-Threonine Kinases Gastrointestinal Stromal Tumors Antineoplastic Agents Phosphotyrosine Protein Tyrosine Phosphatases Proto-Oncogene Proteins c-abl Calcium-Calmodulin-Dependent Protein Kinases Proto-Oncogene Proteins c-kit Proto-Oncogene Proteins Enzyme Activation Genistein Receptor, Epidermal Growth Factor Molecular Sequence Data Enzyme Inhibitors Cell Line Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Mutation Protein Kinase C Tyrosine 3-Monooxygenase Mitogen-Activated Protein Kinase 1 Amino Acid Sequence Phosphoproteins p38 Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase 3 Proto-Oncogene Proteins pp60(c-src)Drug Resistance, Neoplasm Transfection src Homology Domains Proto-Oncogene Proteins c-fyn Protein Binding Cyclic AMP-Dependent Protein Kinases Cell Line, Tumor Leukemia, Myeloid, Chronic-Phase Focal Adhesion Kinase 2 Intracellular Signaling Peptides and Proteins Cells, Cultured Mitogen-Activated Protein Kinase Kinases Mitogen-Activated Protein Kinases fms-Like Tyrosine Kinase 3 JNK Mitogen-Activated Protein Kinases Janus Kinase 2 Receptor, Platelet-Derived Growth Factor alpha Blotting, Western Focal Adhesion Protein-Tyrosine Kinases Focal Adhesion Kinase 1 Tyrphostins Tumor Cells, Cultured Kinetics Adaptor Proteins, Signal Transducing p21-Activated Kinases Genes, abl Protein Structure, Tertiary 3T3 Cells Base Sequence Apoptosis Thiazoles Quinazolines Recombinant Fusion Proteins Indoles Recombinant Proteins Cell Division Isoenzymes Vanadates Precipitin Tests Extracellular Signal-Regulated MAP Kinases Dose-Response Relationship, Drug CDC2 Protein Kinase Receptors, Platelet-Derived Growth Factor K562 Cells Proto-Oncogene Proteins c-akt Binding Sites RNA, Messenger Quinones MAP Kinase Kinase Kinases Phosphotransferases (Alcohol Group Acceptor)Cell Proliferation Protein Tyrosine Phosphatase, Non-Receptor Type 11 Cyclin-Dependent Kinases MAP Kinase Kinase 1 Immunoblotting Epidermal Growth Factor

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