• Hemangioblastomas are vascular tumors that can be found throughout the neuraxis, primarily in the cerebellum and spinal cord. (medscape.com)
  • However, the angiogram is important to define the vascular anatomy for large tumors. (medscape.com)
  • Nonepithelial malignant neoplasms sometimes arise in mucinous tumors, typically as mural nodules. (hindawi.com)
  • By comparison, capillary hemangiomas are the most common vascular tumors of infancy and can be found on skin, mucous membranes, and internal viscera [1]. (jocr.co.in)
  • While most tumors metastatic to the serous membranes are of epithelial origin, cytologists should be aware that non-epithelial neoplasms can also cause malignant effusions including sarcomas, melanomas, germ cell tumors, and, more rarely, brain tumors. (cytojournal.com)
  • Common non-epithelial neoplasms that may cause malignant effusions include malignant melanoma, sarcomas, and other neoplasms including germ cell tumors [ Figure 1 ]. (cytojournal.com)
  • Malignant vascular tumors of bone occur less frequently than hemangiomas. (basicmedicalkey.com)
  • The classification of malignant vascular lesions is still in a state of flux, and controversy continues about the biologic potential of those tumors currently designated as low-grade or borderline endothelial tumors. (basicmedicalkey.com)
  • Histologically, these tumors are typically composed of non-descript spindle to stellate-shaped cells. (ucdavis.edu)
  • Paragangliomas are vascular tumors and demonstrate avid enhancement on both CT and MR. They also often exhibit a characteristic "salt and pepper" appearance on MR. (springeropen.com)
  • It has been postulated that the cells from which the tumors originate are the so-called reserve totipotential subendocardial cells capable of forming vascular structures [8] that have endothelial and neural markers. (scirp.org)
  • Endometrial stromal sarcoma (ESS) is a rare neoplasm accounting for only 0.2% of female genital tract tumors. (biomedcentral.com)
  • Vascular anomalies encompass a variety of malformations and tumors that can result in severe morbidity and mortality in both adults and children. (e-acfs.org)
  • They are divided into two categories: vascular tumors and vascular malformations. (e-acfs.org)
  • Vascular tumors result from the abnormal growth of blood vessels, whereas vascular malformations are structural abnormalities that arise during embryonic development, impacting either blood vessels or lymphatic vessels. (e-acfs.org)
  • Examples of vascular tumors include infantile hemangioma, kaposiform hemangioendothelioma (KH), and tufted angioma (TA). (e-acfs.org)
  • Heterotopic ossification has also been observed in non-traumatic conditions (e.g., infections of the central nervous system, peripheral neuropathy, tetanus, biliary cirrhosis, Peyronie's disease, as well as in association with a variety of benign and malignant neoplasms). (nih.gov)
  • In this pictorial essay, we introduce the representative US findings of many different splenic lesions, including normal sonographic findings, normal variants and congenital anomalies, infectious conditions, benign and malignant neoplasms, and non-neoplastic lesions. (e-ultrasonography.org)
  • Despite the rich vascularity of bone, skeletal vascular lesions are rare, and consequently knowledge of their clinical and pathologic features is still limited. (basicmedicalkey.com)
  • Solitary hemangiomas are the most common vascular lesions of bone. (basicmedicalkey.com)
  • The situation has been further complicated by the human immunodeficiency virus (HIV) pandemic and its associated vascular lesions in bone, such as bacillary angiomatosis and Kaposi's sarcoma. (basicmedicalkey.com)
  • The most significant developments contributing to our knowledge of vascular lesions stem from molecular biology, which provides new information on the molecular mechanisms controlling vascular growth and differentiation. (basicmedicalkey.com)
  • From the diagnostic point of view, these investigations have provided us with a new generation of markers identifying endothelial phenotypes useful in differential diagnosis of vascular lesions. (basicmedicalkey.com)
  • Overall, hamartomatous lesions or low-grade neoplasms predominate in this disease complex. (cap.org)
  • It is characterized by the onset of vascular reddish macules and papules during childhood, lesions are usually monolateral with a linear serpiginous pattern. (biomedcentral.com)
  • He has been referred to our vascular anomalies reference center at 14 years of age due to the increasing in color intensity of the lesions and the recent onset of new macules on the left forearm. (biomedcentral.com)
  • B. henselae infection can be particularly severe for patients with immunocompromising conditions, such as AIDS, in whom vascular proliferative lesions (bacillary angiomatosis and bacillary peliosis) may develop ( 5 ). (cdc.gov)
  • Although hemangioblastoma is a rare tumor of uncertain histotype that typically arises in the cerebellum, quite often in the setting of von Hippel-Lindau disease, Doyle and Fletcher described 22 cases of hemangioblastoma arising at peripheral sites. (medscape.com)
  • The tumor receives a vascular supply from both the anterior and posterior spinal arteries. (medscape.com)
  • citation needed] Possibly Bartonella spp bacteraemia[citation needed] Hemangioendotheliomas may be classified as: Epithelioid hemangioendothelioma is an uncommon vascular tumor of intermediate malignancy that was first described by Steven Billings, Andrew Folpe, and Sharon Weiss in 2003. (wikipedia.org)
  • 601 Spindle-cell hemangioendothelioma) is a vascular tumor that was first described in 1986 by Sharon Weiss, M.D., and commonly presents in a child or young adult who develops blue nodules of firm consistency on a distal extremity. (wikipedia.org)
  • 601 Kaposiform hemangioendothelioma (also known as "Infantile kaposiform hemangioendothelioma") is an uncommon vascular tumor, first described by Niedt, Greco, et al. (wikipedia.org)
  • It is the third most common liver tumor in children, the most common benign vascular tumor of the liver in infancy, and the most common symptomatic liver tumor during the first 6 months of life. (wikipedia.org)
  • The purpose of this report is to describe the features of angiosarcoma arising in mucinous tumor that was misinterpreted as a benign vascular proliferation during the intraoperative consultation. (hindawi.com)
  • Diagnosing non-epithelial malignancies in effusion specimens based entirely upon their cytomorphologic features is difficult because these neoplasms often exhibit considerable morphological overlap and their cytomorphology can differ from the original tumor. (cytojournal.com)
  • Phosphaturic mesenchymal tumor (PMT) is a rare neoplasm most known for its association with tumor-induced osteomalacia (osteogeneic osteomalacia). (ucdavis.edu)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • Epithelioid hemangioma is a rare vascular tumor found in the penis. (biomedcentral.com)
  • Epithelioid hemangioma is a rare vascular tumor that is characterized by capillary vessels lined by epithelioid endothelial cells and accompanied by an inflammatory cell infiltrate [ 1 - 4 ]. (biomedcentral.com)
  • With suspicion of a penile vascular tumor, we performed a local excision of the lesion under general anesthesia. (biomedcentral.com)
  • Cardiac myxomas produce vascular endothelial growth factor, probably inducing angiogenesis for tumor growth. (scirp.org)
  • AVMs are more likely than other types of vascular malformations to be clinically symptomatic. (medscape.com)
  • Similarly, the ISSVA classification system catalogs vascular anomalies into two primary biological categories: vasoproliferative neoplasms (or vascular neoplasms) and vascular malformations. (e-acfs.org)
  • Infantile hemangioendothelioma is a rare benign vascular tumour arising from mesenchymal tissue and is usually located in the liver. (wikipedia.org)
  • She underwent an endometrial biopsy, which demonstrated a müllerian mesenchymal neoplasm that could not be further classified based on histologic findings and immunostains. (cedars-sinai.edu)
  • UTROSCT is a rare uterine mesenchymal neoplasm that tends to occur in middle-aged women. (cedars-sinai.edu)
  • SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)
  • In the remaining cases, angiosarcoma was associated with ovarian teratoma or epithelial neoplasm [ 2 , 4 ]. (hindawi.com)
  • By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
  • Overview of Myeloproliferative Neoplasms Myeloproliferative neoplasms are clonal proliferations of bone marrow hematopoietic stem cells, which can manifest as an increased number of functionally normal platelets, red blood cells (RBCs). (msdmanuals.com)
  • Patients with underlying hypercoagulable states, most frequently myeloproliferative neoplasms, are at highest risk for primary Budd-Chiari syndrome, and multiple genes have been associated. (logicalimages.com)
  • Epithelioid hemangioma, first described in 1969, is a rare vascular lesion that typically arises on the head and distal extremities. (biomedcentral.com)
  • 2 So far, the different variants include classic leiomyoma, 1, 2 leiomyoblastoma, 3 and vascular leiomyoma, 4 this last tumour being the most common histotype. (bmj.com)
  • The finding of pronounced nuclear pleomorphism associated with prominent myxoid matrix in an otherwise leiomyogenic tumour has not been previously reported at this site and must be distinguished from other neoplasms and non-neoplastic processes. (bmj.com)
  • This malignant vascular tumour can develop in cases of long-standing chronic lymphoedema. (medicaljournals.se)
  • The neoplasms may be histologically the same or different, and may be found in the same or different sites. (lookformedical.com)
  • Histologically, Stewart-Treves syndrome displays networks of proliferating vascular channels that dissect the dermal collagen. (medicaljournals.se)
  • Skeletal angiomatoses typically present in two distinct clinical settings: disseminated skeletal angiomatosis, sometimes referred to as cystic angiomatosis, and massive osteolysis (Gorham's disease). (basicmedicalkey.com)
  • Yilmaz & Deshpande occasionally, they are cystic and thus can mimic primary cystic neoplasms of the pancreas. (coek.info)
  • On MR, oligodentrogliomas are typically heterogeneously hypointense or isointense to grey matter on T1 and heterogeneously hyperintense on T2 and FLAIR due to calcification, cystic change and hemorrhage. (blogspot.com)
  • The distinction between Hürthle cell adenoma and carcinoma is based on presence of capsular or vascular invasion, or both. (cap.org)
  • The World Health Organization (2005) defines an epithelial-myoepithelial carcinoma (EMC) as a malignancy composed of two cell types that typically form duct-like structures.1 We present herein an archival case from the parotid gland. (pso-hns.org)
  • Histopathologically, there are 2 types of hepatic hemangioendotheliomas: Type I: Hemagioendotheliomas of this type have multiple vascular channels that are formed by an immature endothelial lining with stromal separation from bile ductules. (wikipedia.org)
  • In brief, vascular endothelial growth factor-A (VEGF-A), which is a part of a large superfamily of growth factors, is required for differentiation of endothelial precursor cells. (basicmedicalkey.com)
  • The prospero related homeobox-1 (PROX1) transcriptional factor and vascular endothelial growth factor receptor-3 (VEGFR3) are responsible for their differentiation into lymphatic endothelial cells. (basicmedicalkey.com)
  • The standard vascular markers used in pathologic differential diagnosis of vascular conditions include von Willebrand factor (vWF), factor VIII-associated protein, platelet endothelial cell adhesion molecule-1 (CD31), human hematopoietic progenitor cell antigen (CD34), v- ets avian erythroblastosis virus E26 oncogene homolog (ERG), human herpes virus 8 (HHV-8), latency-associated nuclear antigen (LANA1), podoplanin (D2-40), and PROX1. (basicmedicalkey.com)
  • We also review the literature to evaluate the incidence of benign vascular anomalies of the penis and their management. (biomedcentral.com)
  • This entity has not yet been included in the classification of the International Society for the Study of Vascular Anomalies. (biomedcentral.com)
  • Advances have been made in the classification and diagnosis of these anomalies, with the International Society for the Study of Vascular Anomalies establishing a widely recognized classification system. (e-acfs.org)
  • When considering reconstructive surgery for facial vascular anomalies, it is important to consider both functional and cosmetic results of the procedure. (e-acfs.org)
  • Overall, the treatment approach for facial vascular anomalies depends on the type, size, location, and severity of the anomaly. (e-acfs.org)
  • The diagnosis and management of vascular anomalies can be challenging due to their variable presentations and complex underlying mechanisms [ 2 , 3 ]. (e-acfs.org)
  • The International Society for the Study of Vascular Anomalies (ISSVA) classification system is a widely accepted approach employed by healthcare professionals who specialize in treating patients with vascular anomalies. (e-acfs.org)
  • In 1982, Mulliken and Glowacki [ 6 ] introduced an organizational system for vascular anomalies based on their pathological characteristics, dividing them into binary groups. (e-acfs.org)
  • Lymphatic blockage may encourage neoplastic transformation due to local immunodeficiency, which could promote vascular oncogenesis (2). (medicaljournals.se)
  • 99% CI, 2.1 to 2.6) and from respiratory, vascular, or neoplastic dis- *The Registrar General of India-Centre for Global Health Research (RGI-CGHR) In- ease. (who.int)
  • T his is a state-of-the-art review of the molecular genetics of pancreatic neoplasms. (coek.info)
  • Although understanding of the molecular features underlying pancreatic neoplasms is still in its infancy, a strong emphasis on the relevance of these findings for the practicing surgical pathologist is provided. (coek.info)
  • INTRODUCTION Pancreatic cancer is the fourth leading cause of cancer death in both men and women in the United States.1 There have been significant advances in our understanding of the genetics of pancreatic neoplasms in the past 2 decades, as well as an explosion of information over the past 3 years, largely because of the availability of whole genome and exome sequencing technologies. (coek.info)
  • This article provides a state-of-the-art review of the molecular genetics of pancreatic neoplasms with a strong emphasis on the relevance of these findings for the practicing surgical pathologist. (coek.info)
  • PANCREATIC DUCTAL ADENOCARCINOMA CLINICAL FEATURES Ductal adenocarcinoma of the pancreas is the most common malignant neoplasm of the pancreas. (coek.info)
  • Also, the incidence of pagetic fractures may be reduced and elevated cardiac output and other vascular disorders may be improved by etidronate disodium therapy. (nih.gov)
  • An arteriovenous malformation (AVM) is a tangled cluster of vessels, typically located in the supratentorial portion of the brain, in which arteries connect directly to veins without an intervening capillary bed. (medscape.com)
  • Capillary hemangiomas and pyogenic granulomas are benign vascular neoplasms that are usually identified clinically by their characteristic features. (jocr.co.in)
  • Clinicians should maintain a high clinical suspicion for both pyogenic granulomas and capillary hemangiomas in children and adults with a vascular soft tissue mass, even after trauma. (jocr.co.in)
  • Capillary hemangiomas and pyogenic granulomas are well-known benign vascular neoplasms. (jocr.co.in)
  • Well-developed capillary vascular networks can be present. (ucdavis.edu)
  • UTROSCT is also typically positive for CD10 and less commonly positive for ER and PR. (cedars-sinai.edu)
  • Synovial sarcoma is a malignant soft-tissue neoplasm that most commonly affects the extremities near to, but not in continuity with, large joints. (medscape.com)
  • What neoplasm is commonly associated with this inherited disorder? (cap.org)
  • The term fibroma is inappropriate because the neoplasm exhibits defined histologic features that differ from those of fibromas and may express malignant behavior. (medscape.com)
  • Infantile hepatic hemangioendothelioma is strongly suggested by the presence of a vascular lesion on imaging studies. (wikipedia.org)
  • Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. (lookformedical.com)
  • Budd-Chiari syndrome is hepatic venous outflow tract obstruction due to either primary vascular occlusion (thrombosis) or secondary occlusion from extrinsic compression (eg, malignancy). (logicalimages.com)
  • The pathogenesis is not fully understood and it is unclear whether it represents a benign vascular neoplasm or a reactive process to a preceding trauma [ 1 ]. (biomedcentral.com)
  • T2-weighted image demonstrates the extensive edema typically associated with hemangioblastomas of the spine. (medscape.com)
  • Malignant PMTs are very rare but typically occur in the setting of repeated recurrences. (ucdavis.edu)
  • A smaller proportion of medulloblastomas occur in one of the cerebellar hemispheres of patients who are typically older (adolescents or young adults), a subset in which the desmoplastic/nodular variant predominates. (medscape.com)
  • In the United States, Budd-Chiari syndrome typically presents in patients in their 30s or 40s with a slight female predominance, but it can occur in patients of all ages. (logicalimages.com)
  • The histopathogenetic classification distinguishes hyaline vascular Castleman disease, plasma cell Castleman disease, human herpesvirus 8 (HHV-8)-associated Castleman disease, and multicentric Castleman disease not otherwise specified. (iriakerala.org)
  • DSRCT was first described by Gerald and Rosai in 1989 as a primitive neoplasm of children and young adults that most frequently occurs in the serosa of the pelvic cavity. (medscape.com)
  • The majority of medulloblastomas arise from the inferior cerebellar vermis, from which they extend into and typically fill the fourth ventricle. (medscape.com)
  • Myxomas are polypoid, round, or oval, and typically pedunculated but can also arise in a sessile fashion. (scirp.org)
  • Angiosarcoma of the ovary is rare but represents an aggressive type of malignant ovarian neoplasms. (hindawi.com)
  • Reninomas are exceedingly rare renin-secreting kidney tumours that derive from juxtaglomerular cells, specialised smooth muscle cells that reside at the vascular inlet of glomeruli. (bvsalud.org)
  • Cholangiocarcinoma is a rare malignant neoplasm and accounts for only 3% of gastrointestinal tumours. (unizg.hr)
  • Angioma serpiginosum is a rare vascular anomaly whose pathogenesis is still unknown. (biomedcentral.com)
  • Clinical evolution, histological and immunohistochemical findings suggest that angioma serpiginosum should be considered as a vascular proliferation. (biomedcentral.com)
  • Although they have macroscopic features that can typically allow them to be identified clinically, a diagnosisis most accurately madehistologically [1]. (jocr.co.in)
  • However, asbestos-associated diseases typically have long latency periods so many patients exposed to asbestos are asymptomatic for years before any clinically apparent asbestos-related disease develops. (cdc.gov)
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
  • Splenic hemangiomas and hemangiosarcomas are neoplasms derived from the splenic vascular endothelium. (nih.gov)
  • Angiectatic blood vessels in the spleen can be congested, but "splenic congestion" is typically a more generalized lesion involving the red pulp sinuses. (nih.gov)
  • Lower extremity edema attributable to vascular compression is also infrequently reported. (radiologytoday.net)
  • Rupture has never get senior colleagues in vascular abnormalities on the white curds. (sci-ed.org)
  • Furthermore, imaging techniques such as magnetic resonance imaging and computed tomography have greatly improved our capacity to visualize and detect vascular abnormalities, enabling more accurate diagnoses. (e-acfs.org)
  • Spinal angiography is indicated for large neoplasms when the diagnosis is indeterminate on MRI. (medscape.com)
  • CT typically confirms the diagnosis by demonstrating a homogenous, unencapsulated low attenuation (fat density) mass within the pelvis displacing the bladder anteriorly and superiorly with resultant elongation of the bladder neck, giving it the characteristic pear shape. (radiologytoday.net)
  • Hyaline vascular Castleman disease represents 90% of the cases of Castleman disease. (iriakerala.org)
  • Each component of both vascular and lymphatic systems has its own expression signature. (basicmedicalkey.com)
  • Hürthle cell neoplasms of the thyroid show a distinct nodule or nodules that are comprised mostly of large oncocytes with distinct cell borders, deeply eosinophilic and granular cytoplasm, and a large nucleus with prominent nucleolus. (cap.org)
  • Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
  • It is typically an incidental imaging finding and is rarely symptomatic. (blogspot.com)
  • some patients have extensive swelling of the spinal cord and only a small neoplasm. (medscape.com)
  • AVMs typically involve the brain but occasionally are associated with the spinal cord and its dura. (medscape.com)
  • Heterotopic ossification due to spinal cord injury typically develops radiographically 1 to 4 months after injury. (nih.gov)
  • A cardiac myxoma is a neoplasm of uncertain histogenesis that occurs only on the endocardial surface. (scirp.org)
  • A failure to intraoperatively recognize this malignant neoplasm may result in incomplete surgical staging procedure or inappropriate clinical management. (hindawi.com)
  • The clinical presentation of Budd-Chiari syndrome varies based on the acuity of vascular compromise. (logicalimages.com)
  • Epilepsy is common in older adults because known risk factors-such as traumatic brain injury, stroke, cerebrovascular disease, neurodegenerative disorders, and neoplasms-increase with age. (cdc.gov)
  • By understanding these fundamental concepts, the radiologist will be able to accurately differentiate a generally benign paraganglioma from a potentially more aggressive head and neck neoplasm. (springeropen.com)
  • Signs and symptoms may include bone pain and/or deformity, neurologic disorders, elevated cardiac output and other vascular disorders, and increased serum alkaline phosphatase and/or urinary hydroxyproline levels. (nih.gov)
  • However, these neoplasms have a distinct nodular appearance without abundant lymphocytes and plasma cells typically seen in Hashimoto thyroiditis. (cap.org)
  • When these cells demonstrate neoplasia within the head and neck, they typically present in characteristic locations including the carotid space, the jugular foramen, the middle ear, and along the course of the vagus nerve. (springeropen.com)
  • Polycythemia vera is a chronic myeloproliferative neoplasm characterized by an increase in morphologically normal red cells (its hallmark), but also white cells and platelets. (msdmanuals.com)
  • My research interest falls into the broad field of regenerative medicine, with emphasis on the way nerve cells and other cell types are affected by small, typically submicron artificial structures. (lu.se)
  • The neoplasm can also invade adjacent brainstem structures, including the cardiorespiratory centers of the fourth ventricular floor. (medscape.com)
  • These neoplasms can show follicular, trabecular, solid, or papillary growth patterns with occasional nuclear grooves or nuclear pseudoinclusions. (cap.org)