• Examples include Alzheimer's disease, amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), osteoporosis and osteoarthritis. (mayo.edu)
  • Restoring neuronal chloride extrusion reverses cognitive decline linked to Alzheimer's disease mutations. (medscape.com)
  • The potential of blood neurofilament light as a marker of neurodegeneration for Alzheimer's disease. (medscape.com)
  • In addition, microglia phagocytoses brain-specific cargo, such as axonal and myelin debris in spinal cord injury or multiple sclerosis, amyloid-β deposits in Alzheimer's disease, and supernumerary synapses in postnatal development. (frontiersin.org)
  • Since then, there has been a flurry of announcements about developments in stem cell research and hints of promising treatments for diseases such as Alzheimer's, Parkinson's and cancer. (cbc.ca)
  • This makes them perfect for a wide range of medical uses, from repairing tissue to treating diseases such as Parkinson's and Alzheimer's. (cbc.ca)
  • Book online now Stem Cell Treatment for ALS, Stem Cell Treatment for Alzheimer's Disease, and Stem Cell Treatment for Multiple Sclerosis at Stemedix, Inc. (placidway.com)
  • What is Alzheimer's Disease? (cellebrationlifesciences.com)
  • Alzheimer's disease is the most commonly observed neurodegenerative disorder associated with memory loss and difficulty with. (cellebrationlifesciences.com)
  • Therapies based on the application of stem cells have great potential in the prevention and treatment of several diseases, such as cancer, diabetes, cardiovascular disease, spinal cord injuries, neurological diseases such as Parkinson's and Alzheimer's, and in the regeneration of various tissues and organs. (bvsalud.org)
  • At Cellebration, we have mastered the technology for isolating the maximum number of viable stem cells from either the autologous sources of your own body or allogeneic with a matched donor to treat various patients with Spinal Cord injury. (cellebrationlifesciences.com)
  • Stem cell treatment for patients with Spinal Cord injury involves administration of concentrated cells in the targeted area to form colonies, adapt the properties of resident stem cells and initiate some of the lost functions that have been compromised by the disease or injury. (cellebrationlifesciences.com)
  • A spinal cord injury involves damage to any part of the spinal cord or nerves at the end of the spinal canal. (mainehealth.org)
  • The spinal cord nerves do not extend into this pouch. (christopherreeve.org)
  • Myelomeningocele diagnosis is a pouch on the back that includes cerebral spinal fluid and part of the spinal cord and nerves. (christopherreeve.org)
  • A neurosurgeon specializes in the medical and surgical care of people with diseases and conditions of the brain and nervous system, including the spinal cord, nerves, muscles, and related blood vessels. (healthgrades.com)
  • Neurosurgeons also perform surgery on the back, neck, brain, spinal cord, and peripheral nerves to treat neurological problems. (healthgrades.com)
  • It could one day be possible to chemically reprogram and repair damaged nerves after spinal cord injury or brain trauma, a new discovery suggests. (sciencedaily.com)
  • The results suggest that we may be able to target specific chemical changes to enhance the growth of nerves after injury to the central nervous system," said lead study author Professor Simone Di Giovanni, from Imperial College London's Department of Medicine. (sciencedaily.com)
  • If damage occurs in the peripheral nervous system, which controls areas outside of the brain and spinal cord, about 30% of the nerves grow back and there is often recovery of movement and function. (sciencedaily.com)
  • traumatic brain injury. (nih.gov)
  • A traumatic spinal cord injury happens from a sudden, harsh blow to the spine that fractures, dislocates, crushes or compresses one or more of the vertebrae. (mainehealth.org)
  • Repeated mild traumatic brain injury triggers pathology in asymptomatic C9ORF72 transgenic mice. (medscape.com)
  • Imaging studies, such as spinal radiography, magnetic resonance imaging (MRI), and/or computed tomography (CT) scanning, can be used to determine the location, severity, and stability of injuries to the vertebral spine and spinal cord. (medscape.com)
  • Spine disease can be painful and affect movement. (mainehealth.org)
  • can reveal vertebral (spinal column) problems, tumors, fractures or degenerative changes in the spine. (mainehealth.org)
  • An opening in the spine occurs if the spinal cord section of the neural tube does not fold and close completely. (christopherreeve.org)
  • Spina Bifida Occulta is a mild form of spina bifida where the spine is open, but the spinal cord is not out of the usual placement. (christopherreeve.org)
  • Meningocele diagnosis is made when there is a pouch of cerebral spinal fluid (the liquid that cushions the brain and spine) protruding on the back over the spine. (christopherreeve.org)
  • Neurosurgeons may also be known by the following names: neurological surgeon, brain surgeon, spine surgery specialist, and spinal cord surgeon. (healthgrades.com)
  • We also compare the behavior of mitochondria in different diseases and outline novel therapeutic strategies for addressing abnormal mitochondrial biological behavior to promote axonal regeneration in neurological diseases and injuries. (nih.gov)
  • If the patient isn't fully awake, or has obvious signs of weakness or neurological injury, emergency diagnostic tests may be needed. (mainehealth.org)
  • When there is preservation of sensation and/or motor activity below the neurological level of insult that includes the lowest sacral segments (S4-S5), the injury is termed incomplete. (dovepress.com)
  • Neurosurgeons are also experts in the prevention of brain and nervous system diseases and in reducing neurological disability. (healthgrades.com)
  • There is a current emphasis on regulation of the metabolism and understanding the pathophysiology associated with obesity and both type 1 and type 2 diabetes mellitus. (umanitoba.ca)
  • And now Stem Cells are also stands as a new weapon against Neurodegenerative Diseases, cardiovascular Diseases. (alliedacademies.org)
  • This damage is currently irreparable, often leaving those who suffer spinal cord injury, stroke or brain trauma with serious impairments like loss of sensation and permanent paralysis. (sciencedaily.com)
  • In most reported cases of SCI, damage can be due to trauma or disease. (cellebrationlifesciences.com)
  • [ 1 ] Neurogenic bladder is a term applied to urinary bladder malfunction due to neurologic dysfunction emanating from internal or external trauma, disease, or injury. (medscape.com)
  • Likewise, the knowledge of stem cell biology is crucial to the development of stem cell therapies, based on tissue engineering applied to dentistry, seeking the regeneration of dental tissues damaged or lost by caries, trauma or genetic diseases. (bvsalud.org)
  • Our major research goals in cardiovascular science and disease are to understand the mechanisms-biophysical and biochemical-of the pathophysiology of different cardiovascular diseases as well as therapies. (umanitoba.ca)
  • Studies in neuroscience and spinal cord injury are centred around understanding the mechanisms-biophysical and biochemical-underlying the pathophysiology of spinal cord injury. (umanitoba.ca)
  • Examples include heart disease, stroke, cancer and diabetes. (mayo.edu)
  • As a result of dependence upon higher brain centers, certain lesions or diseases of the brain (eg, stroke, cancer, dementia) can result in a loss of voluntary control of the normal micturition reflex as well as symptoms such as urinary urgency. (medscape.com)
  • The potential uses for them are vast: from basic research leading to a better understanding of the source of birth defects and cancer to potential treatments for common conditions like arthritis, diabetes, and heart disease to treatments for rarer but severe conditions like spinal cord and brain injuries. (articlecity.com)
  • The damage to his spinal cord was so severe, it left him crippled until the end of his life. (thefutureofthings.com)
  • The loss of muscle function after these types of events can be severe. (adam.com)
  • Spinal Cord Injury is severe damage to the human spinal cord. (cellebrationlifesciences.com)
  • In severe spinal cord injuries, a complete loss of movement (paralysis) and feeling can occur. (merckvetmanual.com)
  • AAVrg's were injected to deliver cre recombinase and/or a red fluorescent protein (RFP) under the human Synapsin 1 promoter (hSyn1) into the spinal cords of C57BL/6 PTENFloxΔ/Δ mice to knockout PTEN (PTEN-KO) in a severe thoracic SCI crush model at both acute and chronic time points. (bvsalud.org)
  • Concerns in spinal cord injury (SCI) include its ability to compromise cardiovascular control, with associated short- and long-term consequences. (medscape.com)
  • A year later, the Ontario government announced it would contribute $1 million to the Gladstone Institute of Cardiovascular Disease in San Francisco. (cbc.ca)
  • An SCI results in a complex series of events that include a lesion within the spinal cord, glial scarring around the lesion, release of chemicals that inhibit axonal growth in the damaged area, and axonal demyelination of nearby but initially unaffected neurons. (dovepress.com)
  • Researchers have found that the insulin-like growth factor 1 (IGF-1) dramatically increases the in vitro growth of corticospinal motor neuron (CSMN) axons - projections that carry nerve impulses to the spinal motor neurons that connect to muscles. (sci-info-pages.com)
  • In addition to providing insight into the development and circuit formation of this critical population of neurons, these results might lead to the future ability to treat motor neuron disorders and spinal cord injuries. (sci-info-pages.com)
  • Although their cell bodies are located in the brain, CSMN axons extend down to the neurons they control in the spinal cord - extending as far as three feet in adult humans. (sci-info-pages.com)
  • These neurons degenerate in motor neuron diseases, and their damage contributes to loss of motor function in spinal cord injuries. (sci-info-pages.com)
  • Since they are embedded among hundreds of other types of neurons in the cerebral cortex, it has been difficult to study CSMN, and little has been known about cellular and molecular factors that control their growth and development. (sci-info-pages.com)
  • A particular field encouraged by the foundation is stem-cell research, with the great hope that it will result in the ability to get cells to differentiate into neurons and support cells to bridge the gap of a spinal cord injury. (thefutureofthings.com)
  • This kind of damage can be differentiated as: death of neurons within the spinal cord, disruption of neuronal pathways due to damaged cells, destruction of the protective myelin sheath carrying nerve signals from the brain to different organs of the body. (cellebrationlifesciences.com)
  • In general, neurons carrying messages down the cord from the brain to other organs of the body are known as Motor Neurons. (cellebrationlifesciences.com)
  • The neurons traveling up the cord to the brain are known as Sensory Neurons, carrying sensory information from the skin, joints, and muscles to control our ability to sense, touch and regulate body temperature. (cellebrationlifesciences.com)
  • Some genetic diseases cause the neurons to degenerate slowly and irreversibly in the first year of life. (merckvetmanual.com)
  • BDA labeling from the motor cortex revealed a dense corticospinal tract (CST) bundle in all groups except chronically treated PTEN-KO mice, indicating a potential long-term toxic effect of PTEN-KO to neurons in the motor cortex which was corroborated by a loss of ß-tubulin III labeling above the lesion within spinal cords after PTEN-KO. (bvsalud.org)
  • A number of large biotech companies and scientists are looking toward stem cells as the basis for a therapeutic solution to cure such illnesses as blindness, diabetes and spinal cord injuries. (thefutureofthings.com)
  • Medical researchers think this technology holds hope for treating conditions such as Park-inson's Disease, diabetes, muscular dystrophy, damaged heart muscle after a heart attack, blindness, and other conditions. (spinalcordinjuryzone.com)
  • Injuries to the cerebrum can cause complete or partial blindness, loss of the sense of smell, seizures, coma, stupor, pacing or circling behavior, and inability to recognize an owner. (merckvetmanual.com)
  • There are associated diagnoses that are found with myelomeningocele that include hydrocephalus (too much cerebral spinal fluid surrounding the brain), which can result in learning disabilities, coordination problems, visual problems and epilepsy. (christopherreeve.org)
  • A type of stem cell found in organs of the body that can be used for regenerative interventions. (mayo.edu)
  • The human spinal cord is a fragile bridge connecting the brain with the other organs of the body. (cellebrationlifesciences.com)
  • The central nervous system which is the brain and the spinal cord is made up of millions of cells, which coordinate and communicate to pass on the information from the brain to other organs of the body via the spinal cord. (cellebrationlifesciences.com)
  • From diagnosing back pain to treating sports-related spinal injuries, MaineHealth experts treat a full range of spinal disorders. (mainehealth.org)
  • Maine Medical Center (MMC) is the state's largest and most complete resource for diagnosing and treating spinal disorders. (mainehealth.org)
  • Dierks T, Schlotawa L, Frese MA, Radhakrishnan K, von Figura K, Schmidt B. Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann-Pick C1 disease - Lysosomal storage disorders caused by defects of non-lysosomal proteins. (medscape.com)
  • This includes investigations into spinal cord physiology, gap junctions and gap junction proteins, axonal growth and regeneration and autonomic control. (umanitoba.ca)
  • We believe this will help further our understanding of mechanisms that could enhance regeneration and physical recovery after CNS injury. (sciencedaily.com)
  • Many spinal cord injury victims are hopeful that this could lead to Regeneration of nerve cells that were severed in an accident. (spinalcordinjuryzone.com)
  • Dr. Kian Leong Lee, who led the study, says this finding "paves the way for advanced studies in cell regeneration and tissue repair, which could ultimately lead to its use in personalized medicine, where stem cells from the same patient could be manipulated to make other types of cells that are genetically matched to the donor. (rejuvalife.md)
  • Potentially they could be used to make new skin, new brain cells, insulin producing cells in the pancreas, or repair nerve tissue in the spinal cord. (spinalcordinjuryzone.com)
  • Research focuses on inflammation, tissue repair and developmental biology in the context of asthma, chronic obstructive pulmonary disease, pulmonary hypertension, and congenital diaphragmatic hernia. (umanitoba.ca)
  • Background: One of the chronic diseases that causes various challenges for patients is spinal cord injury. (ac.ir)
  • Proponents laud its potential for reversing diseases and injuries currently considered chronic and incurable. (spinalcordinjuryzone.com)
  • Chronic Obstructive Pulmonary Disease (COPD) is a term commonly used for a group of lung problems including. (cellebrationlifesciences.com)
  • Restoring function in chronic stages of spinal cord injury (SCI) has often been met with failure or reduced efficacy when regenerative strategies are delayed past the acute or sub-acute stages of injury. (bvsalud.org)
  • We found that a single injection of retrogradely transported adeno-associated viruses (AAVrg) to knockout the phosphatase and tensin homolog protein (PTEN) in chronic SCI can effectively target both damaged and spared axons and transiently restore locomotor functions in near-complete injury models. (bvsalud.org)
  • Regardless of whether treatment was initiated at the time of injury (acute), or three months after SCI (chronic), mice with limited hindlimb joint movement gained hindlimb weight support after treatment. (bvsalud.org)
  • In conclusion, we have found that using AAVrg's to knockout PTEN is an effective manipulation capable of restoring motor functions in chronic SCI and can enhance axon growth of currently unidentified axon populations when delivered acutely after injury. (bvsalud.org)
  • Mucolipidosis type II a/ß with a homozygous missense mutation in the GNPTAB gene. (medscape.com)
  • Lin MH, Pitukcheewanont P. Mucolipidosis type II (I-cell disease) masquerading as rickets: two case reports and review of literature. (medscape.com)
  • Spranger and Wiedermann subsequently classified this disease as mucolipidosis type II (ML II) because it had clinical characteristics that included mucopolysaccharidoses and sphingolipidoses. (medscape.com)
  • Spinal cord injury (SCI) can result in full or partial paralysis, which limits mobility-producing muscular activation. (dovepress.com)
  • The frequency of lysosomal storage diseases in The Netherlands. (medscape.com)
  • As in many of the lysosomal storage diseases, the functional deficiency of lysosomal enzymes results in abnormal cell architecture. (medscape.com)
  • In this mode, cells are infused in the cerebrospinal fluid through the subarachnoid spaces of the spinal canal. (cellebrationlifesciences.com)
  • Similarly, the transplantation of other tissue-specific stem cells, such as stem cells isolated from epithelial and neural tissues, can treat mouse disease models and human patients in which epithelial and neural cells are damaged. (articlecity.com)
  • The present review will summarize the current state of the literature regarding the role of microglial phagocytosis in maintaining tissue homeostasis in health as in disease. (frontiersin.org)
  • The different types of cells that will eventually make up a certain tissue stem from a single "mother cell", hence the term "embryonic stem cells. (spinalcordinjuryzone.com)
  • Using this system, called the Nodal/Activin pathway, scientists will be able to control the eventual type of tissue the stem cells will develop into, simply by adjusting the cell's chemical environment. (rejuvalife.md)
  • Interestingly, although psychomotor retardation is a major manifestation of this disease, the pathologic findings in CNS tissue are not as striking as in other organs. (medscape.com)
  • In vitro cellular experiments and in vivo animal experiments demonstrated that SeNPs-Met-MVs decreased reactive oxygen species (ROS) and malondialdehyde (MDA) levels, increased superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities, and reduced the expression of inflammatory (TNF-α, IL-1ß, and IL-6) and apoptotic (cleaved caspase-3) cytokines in spinal cord tissue after SCI. (bvsalud.org)
  • Overview of Liver Disease Liver disease can manifest in many different ways. (msdmanuals.com)
  • In focused to the product type stem cells market is divided into human embryonic stem cells, adult stem cells, IP sec's, etc. (alliedacademies.org)
  • These adult stem cells are considered multipotent, having the ability to differentiate into different cell types, albeit with a more limited repertoire than embryonic stem cells. (thefutureofthings.com)
  • In rodents, and even in some preliminary trials in humans, human embryonic stem cells have been shown to bridge gaps in spinal cord injuries , allowing restoration of motor functions. (thefutureofthings.com)
  • Adult stem cells can't differentiate into as many other types of cells as embryonic stem cells can. (healthline.com)
  • The first clinical trials involving a patient receiving human embryonic stem cells began in October 2010 at the Shepard Center, a spinal cord injury hospital in Atlanta. (cbc.ca)
  • Scientists say embryonic stem cells are the most useful type because they have the potential to become any type of cell within the body. (cbc.ca)
  • Embryonic stem cells are pluripotent - they have the ability to become virtually any type of cell within the body. (cbc.ca)
  • Fox, who suffers from Parkinson's disease, is putting hope for a cure in medical research using embryonic stem cells. (spinalcordinjuryzone.com)
  • Its name dates back to the 17th century, when the English anatomist Thomas Wharton first identified the jellylike substance that surrounds vital parts inside the umbilical cord. (articlecity.com)
  • Cord blood stem cells are harvested from the umbilical cord after childbirth. (healthline.com)
  • When the lowest sacral levels are without sensory and motor activity, the injury is termed complete. (dovepress.com)
  • The signal transmitted by the brain is routed through 2 intermediate segments (the brainstem and the sacral spinal cord) prior to reaching the bladder. (medscape.com)
  • A type of research study in which researchers learn if a new test or treatment works and is safe. (mayo.edu)
  • Shortly after conception, when cells are just beginning to develop, the brain and the spinal cord are formed from a structure called the embryonic neural tube. (christopherreeve.org)
  • These concerns may be in conjunction with the neural tube issue from pulling, swelling, inflammation, tethered cord or other consequences that are not fully understood. (christopherreeve.org)
  • The Tisch Center ( click here ) takes this approach several steps further, using proprietary methods to transform raw mesenchymal stem cells into a type of stem cell known as neural progenitors, which are specific to the central nervous system. (wheelchairkamikaze.com)
  • Problems with the joints, (such as arthritis), bones (such as deformities), circulation (such as peripheral vascular disease), or even pain can make it difficult to walk properly. (medlineplus.gov)
  • A spinal cord disorder can result from injury or diseases such as arthritis. (mainehealth.org)
  • Microglia are the resident brain macrophages and they have been traditionally studied as orchestrators of the brain inflammatory response during infections and disease. (frontiersin.org)
  • These nanovesicles can cross the blood-spinal cord barrier (BSCB) and deliver SeNPs and Met to the site of injury to exert anti-inflammatory and reactive oxygen species scavenging effects. (bvsalud.org)
  • The biochemical defect in I-cell disease involves the first step in the addition of the mannose-6-phosphate moiety. (medscape.com)
  • Injuries to most parts of the nervous system, for instance, are considered nearly impossible to heal naturally, if at all. (thefutureofthings.com)
  • A change in an animal's ability to sense its environment can be caused by disease in either the central nervous system or the peripheral nervous system. (merckvetmanual.com)
  • Some injuries to the nervous system can cause damage that is not evident until 24 to 48 hours after the injury occurs. (merckvetmanual.com)
  • Normal voiding is essentially a spinal reflex modulated by the central nervous system (brain and spinal cord), which coordinates function of the bladder and urethra. (medscape.com)
  • The central nervous system is composed of the brain, brain stem, and the spinal cord. (medscape.com)
  • Abstract INTRODUCTION: Brazil ranks 5th in the number of deaths due to road injuries. (scielo.br)
  • The research may lead to treatments for motor neuron disease and spinal cord injury. (sci-info-pages.com)
  • In addition to its potential applications for disease treatments, stem cells are now being recognized for their benefits in aiding cosmetic procedures. (rejuvalife.md)
  • Is this type of stem cell treatment considered a cure, or can patients expect to require repeated treatments in order to maintain whatever benefits they achieve? (wheelchairkamikaze.com)
  • I anticipate less frequent treatments will be needed to maintain benefit for the duration of the disease until we find a cure. (wheelchairkamikaze.com)
  • And would this hold true for any type of regenerative stem cell treatment, such as those being offered by some of the for-profit clinics at which many patients are seeking a single treatment or a single round of treatments over a relatively short period of time? (wheelchairkamikaze.com)
  • Recent evidence indicates that altered degradation rate of mutant proteins represents a pathogenic mechanism underlying genetic diseases. (frontiersin.org)
  • However, several studies and reports on disabilities, visual and hearing impairments, ageing populations and the burden of noncommunicable diseases, mental health conditions and injuries as well as data from emergency contexts show limited access to appropriate, affordable and quality products. (who.int)
  • With the rise in injuries and noncommunicable diseases as well as ageing populations, the demand for rehabilitation services and assistive technology is increasing. (who.int)
  • Brain imaging is not necessary to diagnose I-cell disease, although it is often performed during evaluation of developmental delay. (medscape.com)
  • The worldwide Stem cell & regenerative medicines market is functional with several parameters like product type, application, sources, geography and users. (alliedacademies.org)
  • Whereas, regenerative medicines applied the potential of these stem cells to regenerate, repair & replace tissues or the organ which are affected due to injury, natural aging process, and some diseases. (alliedacademies.org)
  • A type of cell derived from amniotic fluid, which is the liquid that surrounds a developing fetus in the amniotic sac. (mayo.edu)
  • The effects of an injury on sensory and motor functions depend on its location and severity. (merckvetmanual.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • Therefore, the Centers for Disease Control and Prevention (CDC) recommends women take 400 mcg of folic acid supplement daily but if pregnancy is considered, this amount should be raised to 4000 mcg. (christopherreeve.org)
  • Suggested citation: Centers for Disease Control and Prevention. (cdc.gov)
  • The process by which an undifferentiated stem cell becomes a specialized cell type, such as a heart cell or brain cell. (mayo.edu)
  • A type of undifferentiated stem cell found in embryos. (mayo.edu)
  • Use of this type of stem cell has significantly decreased in recent years due to the discovery of induced pluripotent stem cells. (mayo.edu)
  • This type of stem cell is very versatile and has a wide range of uses, though procuring them entails medical and ethical challenges. (articlecity.com)
  • For example, hematopoietic stem cells are a type of adult stem cell found in bone marrow. (healthline.com)
  • Doctors have been performing stem cell transplants, also known as bone marrow transplants, for decades using hematopoietic stem cells in order to treat certain types of cancer. (healthline.com)
  • In May 2007, Ontario and California announced a $30-million stem cell research deal aimed at finding new therapies for those diseases. (cbc.ca)
  • In 2004, California voters sent the message that embryonic stem cell research was a worthy endeavor with viable prospects for curing disease. (spinalcordinjuryzone.com)
  • Although still in its early phases, stem cell research is producing some of the most promising advances in modern medicine, and the potential it may have for disease treatment in the future is simply astonishing. (rejuvalife.md)
  • A research team from the Genome Institute of Singapore, in collaboration with the Cancer Science Institute of Singapore, discovered that the type of cell that a stem cell will eventually turn into is actually controlled by a single communication system. (rejuvalife.md)
  • Most previous attempts at using stem cells to repair MS damage have involved intravenously infusing a basic type of stem cell (called mesenchymal stem cells) back into the patient from which they were taken. (wheelchairkamikaze.com)
  • Using specific types of stem cells to repair damaged tissues and treat disease. (mayo.edu)
  • It is the study of how things go wrong in living things and affect the body's systems, causing functional changes that can lead to health consequences such as a disease or a disorder. (umanitoba.ca)
  • Despite recent findings regarding the functional implications of TRPM4 in cardiac diseases, the molecular and cellular mechanisms leading to altered conduction are poorly understood. (frontiersin.org)
  • For example, because hematopoietic stem cells can reconstitute the entire blood system, bone marrow transplantation has long been used in the clinic to treat various diseases. (articlecity.com)
  • Different types of walking problems occur without a person's control. (medlineplus.gov)
  • Some health conditions might occur in higher incidence with differing types of spina bifida. (christopherreeve.org)