Types prevent the progression 1999 type i diabetes patients diabetes mellitus type 1. Medical search. Frequent questions

Risk factors for prediabetes include family history of diabetes, older age, women who have a history of gestational diabetes or high birth weight babies (greater than 9 lbs. (wikipedia.org)
The prominent role of autophagy signaling pathway was supported by the alteration of autophagy markers in patients and animal models of T1DM, T2DM, and gestational diabetes. (frontiersin.org)
Globally, gestational diabetes mellitus complicates 1 in 6 pregnancies and increases future risk of type 2 diabetes and cardiovascular disease in the affected women. (biomedcentral.com)
Our aim was to systematically review the existing literature on cardiovascular follow-up after gestational diabetes, the utility of eHealth technology for this purpose, and to identify research gaps. (biomedcentral.com)
No studies were identified that examined follow-up regarding long-term overall cardiovascular risk after gestational diabetes. (biomedcentral.com)
This scoping review of the existing literature revealed neither an established systematic cardiovascular follow-up strategy for women after gestational diabetes nor evidence that eHealth technologies are superior to conventional follow-up. (biomedcentral.com)
Gestational diabetes mellitus (GDM) is a common complication of pregnancy, with a rising incidence, affecting around 1 in 6 births globally, with prevalence varying across different regions and populations [ 1 ]. (biomedcentral.com)

Cardiac complications are the leading cause of morbidity and mortality in diabetic patients [ 1 ]. (hindawi.com)
Moreover, the role of vitamin D supplementation in the prevention of both types of diabetes is analysed together with its role in improving glycemic control in diabetic patients. (vitamindwiki.com)
Although in all diabetic patients, GFR is initially normal or mildly elevated with no histological alterations, it progresses to produce thick glomerular basement membrane and expand to mesangial, followed by high glomerular capillary pressure and microalbuminuria. (scialert.net)
Regulation of Weight and diabetes are highly recommended in obese and diabetic patients to prevent the subsequent renal disease. (researchsquare.com)
Machine-learning to stratify diabetic patients using novel cardiac biomarkers and integrative genomics. (wvu.edu)
In this context, there is an interest in the possible effect of supragingival biofilm control on the subgingival environment in untreated periodontitis sites in diabetic patients, since, in previous studies, these patients presented with some altered biofilm compositions, with a higher prevalence of periodontal pathogens. (bvsalud.org)
Thus, the aim of the present study was to determine clinical changes in type 2 diabetic patients after 28 days of strict supragingival plaque control compared with non-diabetic patients. (bvsalud.org)

We and others have reported that myocardial inflammation develops in human patients and experimental models of type 1 (T1DM) and type 2 (T2DM) diabetes mellitus [ 8 , 14 , 15 ]. (hindawi.com)
T3 levels are also elevated in patients with type 1 diabetes mellitus (T1DM)-a common complication of the disease (Wang et al. (99thdynasty.com)

Diabetes Mellitus (DM) is a group of metabolic disease characterized by hyperglycemia resulting from defects secretion or insulin action, or both. (bvsalud.org)

Although case series and population-based surveillance have identified several possible host risk factors for the development of invasive GAS disease, including age, Native American ethnicity, HIV infection, diabetes mellitus, cardiovascular disease, alcoholism, and other chronic diseases ( 1 - 3 ), these studies have not been able to assess household risk factors. (cdc.gov)
Women who have had GDM in their pregnancy have an increased risk of type 2 diabetes and cardiovascular disease later in life compared to those with normoglycemic pregnancies [ 3 ]. (biomedcentral.com)
This nutrient protects vital cellular energy and shields against diabetes, obesity, cardiovascular disease, and neurodegeneration. (lifeextension.com)
5 Ongoing clinical trials across the globe show the promise of lipoic acid's benefits on a wide range of diseases-from diabetes to cardiovascular disease to Alzheimer's and countless more. (lifeextension.com)
In this report, you will discover how the alpha lipoic acid benefits vital cellular energy while shielding against and possibly reversing the damaging effects of disorders that include diabetes, obesity, cardiovascular disease, neurodegeneration, and cancer. (lifeextension.com)

The incidence of both type 2 and type 1 diabetes mellitus has been increasing worldwide. (vitamindwiki.com)
2-11 The incidence may be higher in younger patients that are intravenous drug abusers. (wheelessonline.com)
The objective of this study was to analyze the impact of obesity and diabetes on CKD and ESRD incidence and prevalence. (researchsquare.com)
Notably, the association of obesity and diabetes potentially increases the incidence and prevalence of CKD and ESRD. (researchsquare.com)
Taken together, obesity and diabetes are significantly associated with the increasing incidence and prevalence of CKD and ESRD. (researchsquare.com)

Prediabetes is a component of the metabolic syndrome and is characterized by elevated blood sugar levels that fall below the threshold to diagnose diabetes mellitus. (wikipedia.org)
Diabetes mellitus (DM) is one of the most prevalent metabolic diseases worldwide. (frontiersin.org)
Obesity is well known for causing morbidity, mortality, disability and has been associated to an increasing number of cardiovascular and metabolic comorbidities, such as hypertension and diabetes mellitus (DM). (researchsquare.com)
30,31 Lipoic acid has been particularly effective in reducing body weight and BMI in patients taking antipsychotics, which are known for causing weight gain and other metabolic disturbances. (lifeextension.com)
Metabolic syndrome raises the risk of diabetes and heart disease. (lifeextension.com)
1999). Elevated T3 levels were associated with the obesity-associated metabolic syndrome (Obeso and colleagues 2010), anabolic hormones list. (99thdynasty.com)

Impaired fasting glycemia or impaired fasting glucose (IFG) refers to a condition in which the fasting blood glucose is elevated above what is considered normal levels but is not high enough to be classified as diabetes mellitus. (wikipedia.org)
Some patients with impaired fasting glucose also may be diagnosed with impaired glucose tolerance, but many have normal responses to a glucose tolerance test. (wikipedia.org)

16-20 In a recent placebo-controlled clinical trial, researchers found that after only 6 months of lipoic acid supplementation, patients with type II diabetes had reduced fasting blood glucose and lowered levels of oxidized lipids. (lifeextension.com)
There is some evidence to suggest that coenzyme Q 10 supplementation may be a useful adjunct to conventional medical therapy for congestive heart failure and in patients undergoing coronary artery bypass graft surgery. (oregonstate.edu)
There are currently no proven therapeutic benefits of coenzyme Q 10 supplementation in diabetes mellitus , neurodegenerative diseases , inherited ataxias , or breast cancer . (oregonstate.edu)

Prevention of hypoglycaemia is an important part of diabetes mellitus management and strategies include patient education, glucose monitoring, appropriate adjustment of diet and medications in relation to everyday circumstances including physical exercise, and the application of new technologies such as real-time continuous glucose monitoring, modified insulin pumps and the artificial pancreas. (nature.com)
The present strategy urges Member States to evaluate the magnitude of diabetes and identify and improve areas of intervention in terms of primary, secondary and tertiary prevention activities. (who.int)
This document examines the situation of diabetes (Type 2) in the African Region and proposes a strategy for its prevention and control. (who.int)
Through of the evaluation for HRV autonomic maneuvers can identify objectively cardiovascular autonomic neuropathy early stages and provide treatment options that based on control of symptoms and prevention of disease progression. (bvsalud.org)

We also address the potential role of vitamin D deficiency in the development of macro- and microvascular complications in diabetes. (vitamindwiki.com)

The first US Food and Drug Administration-approved immunotherapy for type 1 diabetes, the anti-CD3 antibody teplizumab, delays symptomatic type 1 diabetes onset by 2-3 years [ 4 ], opening the door for the future clinical application of antigen-specific approaches with potentially superior immunoregulatory properties [ 5 ]. (springer.com)
Despite recent advancements in clinical drugs, diabetes treatment still needs further progress. (frontiersin.org)
Over 15 randomized clinical studies have shown that intravenous administration of 300-600 mg of lipoic acid a day greatly improves nerve function and relieves pain symptoms in diabetic neuropathy patients. (lifeextension.com)
Most patients with DH have clinical features of enteropathy that are similar to those of CD. (ndnr.com)
To determine the clinical changes occurred in chronic periodontitis patients presenting uncontrolled type 2 diabetes mellitus after a supragingival plaque control period. (bvsalud.org)
Previous studies have evaluated the relationship between supragingival plaque control and clinical and microbiological effects on subgingival areas, reporting a positive effect in systemically healthy subjects with periodontitis, i.e., a reduction in probing depth and some periodontal pathogens and preventing re-colonization 9-11 . (bvsalud.org)
Several single gene disorders share clinical and radiologic characteristics with multiple sclerosis and have the potential to be overlooked in the differential diagnostic evaluation of both adult and paediatric patients with multiple sclerosis. (medscape.com)
Here we review single gene disorders that have the potential to mimic multiple sclerosis, provide an overview of clinical and investigational characteristics of each disorder, and present guidelines for when clinicians should suspect an underlying heritable disorder that requires diagnostic confirmation in a patient with a definite or probable diagnosis of multiple sclerosis. (medscape.com)
Patients with multiple sclerosis are classified according to their clinical phenotype, with ~85% following a relapsing-remitting course (relapsing-remitting multiple sclerosis) characterized by recurrent, acute neurological deficits punctuating periods of latency or remission (Lublin and Reingold, 1996). (medscape.com)
In the absence of pathognomonic clinical findings or a definitive laboratory test, the diagnosis of multiple sclerosis remains challenging in many patients, and diagnostic criteria emphasize the caveat of 'no better explanation' for a patient's clinical presentation and MRI findings. (medscape.com)

In various mouse and rat models of obesity and type 1 and 2 diabetes mellitus, eCBs generated in various renal cells activate CB 1 receptors and contribute to the development of oxidative stress, inflammation, and renal fibrosis. (degruyter.com)
Prevalence of insulin resistance, obesity and type 2 diabetes in the US adult population. (biomedcentral.com)

Diabetes is a chronic disease characterized by chronic hyperglycaemia which requires lifelong treatment. (who.int)
2 WHO, WHO/IDF report of consultation: Definition and diagnosis of diabetes mellitus and intermediate hyperglycaemia , Geneva, World Health Organization, 2006. (who.int)

in 1971 [ 2 ], diabetic cardiomyopathy (DCM) is characterized by the direct effect of diabetes on cardiac structure and function in the absence of coronary artery disease, hypertension, or other cardiac pathologies. (hindawi.com)

Another pathway, TGF-β signaling pathway, appears to play a part in the progression of diabetes, insulin resistance, and autoimmunity in both type 1 and 2 diabetes and complications in diabetes. (frontiersin.org)
TGF-β, especially TGF-β1 as an uppermost isoform of TGF-β superfamily, may play a very essential role in the development of insulin resistance and obesity and finally, diabetes. (frontiersin.org)
Vitamin D may have a role in the pathogenic mechanisms predisposing to type 2 diabetes by modulating insulin resistance and/or pancreatic ß-cell function. (vitamindwiki.com)
Role of vitamin D in the development of insulin resistance and type 2 diabetes . (vitamindwiki.com)

Interestingly, overweight and obese ESRD patients on dialysis had a significant survival advantage in comparison to lean body weight patients. (researchsquare.com)
Even without a change in diet or exercise, large doses of lipoic acid ( 800-1,800 mg/day ) have produced moderate weight loss in obese patients. (lifeextension.com)
Collectively, these observations regarding distinct subsets of metabolically-compromised individuals (see Fig. 1 ) reflect the highly complex and multifactorial aetiology of T2D in obese and non-obese individuals. (biomedcentral.com)

Notwithstanding this achievement, we are still far from a nuanced understanding of how islet autoimmunity originates and propagates during the development of type 1 diabetes and why it is so heterogeneous among individuals. (springer.com)
Since the early 1990s, patients with both CMT1 and CMT2, while often clinically similar, were found to be genetically heterogeneous. (medscape.com)

This study examines exciting new hallmarks for the strict involvement of autophagy and TGF-β signaling pathways in the pathogenesis of diabetes and the design of novel therapeutic strategies. (frontiersin.org)
Pathogenesis of type 2 diabetes mellitus. (vitamindwiki.com)
The pathogenesis of insulin-dependent diabetes mellitus. (vitamindwiki.com)

5,14 That prevalence of this infection increases with age is possibly due to a number of factors: the increasing age of the population, increasing number of patients on renal replacement therapy, increasing number of patients with immunosuppressive medications and increasing rates of bacteremia due to intravascular devices and other forms of instrumentation. (wheelessonline.com)
Lipoic acid increases the abundance of other protective antioxidants while improving mitochondrial function and preventing glycation-induced damage in the kidney and blood vessels of those with diabetes-thus defending against diabetic kidney disease, vision loss, and vascular dysfunction. (lifeextension.com)
Chronic periodontitis results from the presence of complex microbial communities in the subgingival sulcus 1 , and diabetes mellitus, especially if poorly controlled, increases significantly risk for development of extensive and severe diseases 2 . (bvsalud.org)

Whereas coma and seizures are well-recognized neurological sequelae of hypoglycaemia, much interest is currently focused on the potential for hypoglycaemia to cause dangerous and life-threatening cardiac complications, such as arrhythmias and myocardial ischaemia, and whether recurrent severe hypoglycaemia can cause permanent cognitive impairment or promote cognitive decline and accelerate the onset of dementia in middle-aged and elderly people with diabetes mellitus. (nature.com)
Enhanced antioxidant capacity prevents epitranscriptomic and cardiac alterations in adult offspring gestationally-exposed to ENM. (wvu.edu)
Thus, it is possible to prevent cardiac events arising from complications of autonomic neuropathy, such as resting tachycardia and silent myocardial infarction, among others 16 . (bvsalud.org)

Type 1 diabetes results from the poorly understood process of islet autoimmunity, which ultimately leads to the loss of functional pancreatic beta cells. (springer.com)

Patients should monitor for signs and symptoms of type 2 diabetes mellitus such as increased thirst, increased urination, and feeling tired. (wikipedia.org)
A sporadic type frequently has a classic presentation: itching and burning are usually the first symptoms and may occur up to 12 hours before the lesions become visible. (ndnr.com)
Approximately 15% of patients follow a primary progressive or progressive relapsing course from disease onset, usually characterized by symptoms of progressive myelopathy (gait instability, spasticity, bladder symptoms) and cognitive impairment. (medscape.com)

Type 1 diabetes results from organ-specific autoimmunity, which eliminates most of the insulin-producing pancreatic beta cells. (springer.com)
While the role of islet autoimmunity remains unquestioned, the role of the islets as active participants has only recently become accepted [ 1 ]. (springer.com)
Undoubtedly, sustained efforts by the global type 1 diabetes research community to understand the basis of T cell-driven autoimmunity in type 1 diabetes have paid dividends. (springer.com)
Here, we draw upon studies that have shed light on the initiation and progression of islet autoimmunity from the point of view of the beta cell. (springer.com)
We advance the hypothesis that antigen presentation by beta cells, their stress responses and functional heterogeneity are critical factors that will provide clues towards solving the enigma posed by islet autoimmunity in type 1 diabetes. (springer.com)
Central to solving the puzzle as to how type 1 diabetes occurs will be to identify the elusive cause(s) of initial islet autoimmunity. (springer.com)

Long term diabetes and poor glycemic control are the most important risk factors for DN development ( DCCT Research Group, 1993 ). (scialert.net)

Here, we review some of the recent advances and studies that highlight the roles of these changes as well as antigen presentation and stress response pathways in beta cells in the onset and propagation of the autoimmune process in type 1 diabetes. (springer.com)

Immunohistopathological studies of pancreases from individuals with type 1 diabetes are generally compatible with these observations made in mice (see references below) but have exposed additional phenomena peculiar to the natural history of the disease in humans. (springer.com)
An estimated 9,500 cases of invasive GAS disease occurred in the United States in 1999, resulting in approximately 1,100 deaths. (cdc.gov)
Diabetes is a methabolic disease characterized by hyperglycemia, with high morbidity and mortility worldwide. (scialert.net)
This is why a number of patients present late in the course of HIV disease. (openvirologyjournal.com)
However, even for CMT1 a heated debate has focused on the relative contribution of axonal versus demyelinative damage to the disease manifestations and progression. (medscape.com)
in others (eg, certain cases of Charcot-Marie-Tooth disease type 1A (CMT1A) and inherited brachial plexus neuropathy [IBPN]/hereditary neuralgic amyotrophy [HNA]), proximal weakness predominates. (medscape.com)
Obesity and diabetes are the main causes of chronic kidney disease (CKD) and end stage renal disease (ESRD). (researchsquare.com)
Results from the cohort, case-control and cross-sectional studies pointed out a positive association between obesity, diabetes and risks for renal disease outcomes. (researchsquare.com)
For many years, scientists have researched how lipoic acid affects insulin sensitivity and the severity of diabetes-related disorders, including heart disease, stroke, glaucoma, neuropathic pain, and kidney disease. (lifeextension.com)
Clearly, DH is a chronic disease, but in some patients it has a continuous and more severe character, while in others it seems to be more sporadic and relapsing-remitting in nature. (ndnr.com)
Several reviews suggested no clear evidence that any of the progestin agents were superior to placebo in their safety and efficacy in preventing breast cancer progression or survival in women with breast cancer at a very sensitive time in their disease trajectory, steroids for muscle enhancement. (99thdynasty.com)
Our goal is to provide insight regarding exercise strategies that might be useful as 'precision medicine' to prevent/treat this disease. (biomedcentral.com)
Consequently, an exercise strategy to prevent/treat this disease should be geared toward improving insulin sensitivity both from an acute and chronic standpoint. (biomedcentral.com)
This has resonance because ectopic fat accumulation appears to represent a central component of disease progression regardless of whether obesity is also part of the equation. (biomedcentral.com)
Moreover, ~ 34% of American adults have prediabetes, which means they are at increased risk for developing T2D and comortalities including heart disease and stroke [ 1 ]. (biomedcentral.com)
Diabetes mellitus is a chronic disease whose global spread has given it the characteristics of a pandemic. (who.int)
These inconsistencies may result partly from differences in sample size, dosage, geographic location, and disease progression across studies. (cdc.gov)
The disease is associated to increased mortality and high risk development of complications micro-and macrovascular complications, as well as neuropathies, blindness, kidney failure and limb amputations 1,3 . (bvsalud.org)

Prediabetes is more accurately considered an early stage of diabetes as health complications associated with type 2 diabetes often occur before the diagnosis of diabetes. (wikipedia.org)
Mauritius, it reaches 20%.6 The global prevalence was estimated at 2.8% in 2000, with projections of 1 WHO, WHO/IDF report of consultation: Definition, diagnosis and classification of diabetes mellitus and its complications, Geneva, World Health Organization, 1999. (who.int)
Early, accurate diagnosis is critical to effective patient management and counselling, but assignment of an incorrect diagnosis of multiple sclerosis remains a frequent concern. (medscape.com)

Regardless of the source of the infection, an infection of the spine should be quickly diagnosed in order to prevent structural instability or neurologic compromise. (wheelessonline.com)
Three major routes of spread are: (1) hematogenous spread from a distant infection, (2) direct inoculation from trauma, (3) direct inoculation following invasive spinal diagnostic procedures and from spinal surgery. (wheelessonline.com)

For example, the single-autoantibody-positive stage generally has a significantly lower of risk of progression [ 12 ] and as such is not considered as the earliest stage of type 1 diabetes. (springer.com)
The relative proportion of stabilized aneurysms increased significantly as the age increased ( P P P = 0.012), diabetes ( P = 0.007), and height ≥3 mm ( P = 0.007) were correlated with stabilized aneurysms. (surgicalneurologyint.com)

There is evidence that chronic progression of hypertrophy, fibrosis, and ventricular dysfunction is correlated with a local increase in cytokines [ 16 ] and activation of NF- B [ 17 , 18 ]. (hindawi.com)

Pharmaceutical companies are focusing massive resources to develop a drug that targets mitochondrial dysfunction , 1 one of the major causes of the chronic diseases of aging. (lifeextension.com)
Cardiovascular autonomic neuropathy is a common dysfunction autonomic found in DM patients DM, causing abnormalities in heart rate control, and dynamic vascular 4 . (bvsalud.org)

As summarized elsewhere (1), the combination of a declining birth rate and an increased average life span is expected to increase the proportion of the population aged 65 years and older in the United States from 12.4% in 2000 to 19.6% in 2030. (cdc.gov)
Globally, the number of older adults (aged 65 years and older) is projected to increase even more dramatically - more than doubling from 420 million in 2000 to 973 million in 2030 (1). (cdc.gov)

Consequently, several therapeutic agents such as adiponectin, ezetimibe, GABA tea, geniposide, liraglutide, guava extract, and vitamin D were shown to inhibit diabetes and its complications through modulation of the autophagy pathway. (frontiersin.org)
Natural agents including compounds as resveratrol, puerarin, curcumin, hesperidin and silymarin, and extracts of propolis, Lycopus lucidus , and Momordica charantia have been shown to combat diabetes via modulation of TGF-β signaling pathway. (frontiersin.org)

The energy released when the protons flow back into the mitochondrial interior is used to form ATP ( Figure 2 ) (1) . (oregonstate.edu)

Symptomatic, or 'stage 3' type 1 diabetes, generally occurs following two clinically tractable stages consisting of seroconversion and the presence of two or more autoantibodies, followed by development of dysglycaemia [ 11 ]. (springer.com)
41 ] Rupture of an IA occurs in relatively young people and has a high fatality and morbidity rate, but the majority of patients with incidentally detected IA have a benign course. (surgicalneurologyint.com)
Vertebral osteomyelitis mostly occurs in adults, with the majority occurring in patients over 50 years old. (wheelessonline.com)

To examine the prognosis of patients who present with very advanced HIV-induced immunodeficiency, and their response to highly active antiretroviral therapy (HAART), a series of 101 treatment naïve patients from the Serbian cohort of HIV infected patients, who presented with a CD4 count of ≤ 50/µL before commencing HAART, was retrospectively analyzed and factors influencing response to HAART and survival investigated. (openvirologyjournal.com)

Lack of physical activity is a risk factor for type 2 diabetes and physical activity can reduce the risk of progressing to type 2 diabetes. (wikipedia.org)
In addition, surveillance studies identified possible risk factors by comparing prevalence of host factors among GAS patients (by using medical record data) to prevalence of host factors among the general population using population-based estimates ( 1 , 2 ). (cdc.gov)
6 14 28 39 ] In patients with unruptured IA, physicians decide whether to treat preventively by balancing the risk of treatment against the risk of rupture. (surgicalneurologyint.com)
Risk factors for infections of the spine involve conditions that weaken the patient's immune system, such conditions include diabetes mellitus, use of immunosuppressant medications, cancer, HIV/AIDS, malnutrition, history of an organ transplant and intravenous drug abuse. (wheelessonline.com)

In the African Region, efforts made to create an environment that enhances the fight against diabetes include adoption of resolutions AFR/RC50/R4 on noncommunicable diseases: strategy for the African Region, in 2000, and AFR/RC55/R4: cardiovascular diseases in the African Region, in 2005. (who.int)

Although all diabetic cells are exposed to elevated levels of plasma glucose, hyperglycemic damage is limited to those cell types that are unable to down regulate glucose transport into the cell (e.g., endothelial cells), leading to intra-cellular hyperglycemia ( Brownlee, 2001 ). (scialert.net)

1-3 As such, atypical DH is often misdiagnosed as eczema, psoriasis, or herpes simplex eruptions. (ndnr.com)

Genetic Variations in the Vitamin D Receptor Predict Type 2 diabetes and Myocardial Infarction in a Community-Based Population: The Tromsø Study. (vitamindwiki.com)
Recent statistics indicate that 23.1 million people (7.2% of the population) in the US have diabetes with another 7.2 million afflicted, but not diagnosed [ 1 ]. (biomedcentral.com)

Mild (self-treated) and severe (requiring help) hypoglycaemia episodes are more common in type 1 diabetes mellitus but people with insulin-treated type 2 diabetes mellitus are also exposed to frequent hypoglycaemic events, many of which occur during sleep. (nature.com)
Type 2 diabetes, which is the most common form, can be life threatening due to its complications, particularly, cardiovascular diseases. (who.int)

Specifically, evidence supports that several signaling pathways play pivotal roles in the development of diabetes. (frontiersin.org)
The involvement of autophagy in the development of diabetes is corroborated by affecting the physiology and role of pancreatic β cells and the homeostasis of glucose. (frontiersin.org)
In this review we discuss up to date evidence linking vitamin D with the development of diabetes. (vitamindwiki.com)

The distance of Paschoal test was similar between groups of individuals with diabetes and their respective controls. (bvsalud.org)

Because the therapeutic potential of globally acting CB 1 receptor antagonists in these conditions is limited due to their neuropsychiatric adverse effects, the recent development of peripherally restricted CB 1 receptor antagonists may represent a novel pharmacological approach in treating renal diseases. (degruyter.com)

After a mean of three years (range 1-9) of treatment with PI-based and/or NNRTI-based regimens, a favorable response was achieved in 54.5% of the patients, treatment failure occurred in 13.9%, while 31.7% had a dissociative immunological/virological response. (openvirologyjournal.com)
In older patients (≥65 years of age), multivariate logistic regression revealed that only diabetes was associated with stabilized aneurysms ( P = 0.027). (surgicalneurologyint.com)
In patients ≥65 years of age, diabetes mellitus may highly predict the stabilized aneurysms. (surgicalneurologyint.com)
The recreational, psychoactive, and medicinal effects of marijuana, many of which have important therapeutic potentials, have been recognized for thousands of years [ 1 ]. (degruyter.com)

This review provides keen insights into novel therapeutic strategies for the medical care of diabetes. (frontiersin.org)

Hypoglycaemia is a frequent adverse effect of treatment of diabetes mellitus with insulin and sulphonylureas. (nature.com)
The most frequent form is Type 2 diabetes which represents more than 85% of the cases. (who.int)

Dysregulated autophagy in pancreatic β cells due to hyperglycemia, oxidative stress, and inflammation is associated with diabetes and accompanied by dysregulated autophagy in insulin target tissues and the progression of diabetic complications. (frontiersin.org)
It is characterized by hyperglycemia and defective production and/or secretion of insulin and complications in the heart, kidney, and neural system leading to death, which have drawn notable attention to the management of diabetes. (frontiersin.org)
Hyperglycemia and resultant advanced glycation end product formation, which is one of several pathways thought to lead to the vascular complications with diabetes, are also involved in the pathophysiology of periodontitis in diabetic subjects 3 , leading to an imbalanced release of pro- and anti-inflammatory cytokines 4-6 and osteoclastogenesis-related factors 7 . (bvsalud.org)

Evaluation of heart rate variability (HRV) during cardiovascular autonomic tests and functional capacity of patients with type 1 and type 2 DM. (bvsalud.org)

For many people, prediabetes and diabetes are diagnosed through a routine screening at a check-up. (wikipedia.org)
However, it now is clear that there is a range of residual beta cells that are dysfunctional in people with newly diagnosed type 1 diabetes [ 2 ]. (springer.com)
Affecting up to around two out of every three people with diabetes, neuropathy is nervous system damage that can produce unbearable pain in the legs and feet. (lifeextension.com)
Endogenous synthesis and dietary intake provide sufficient coenzyme Q 10 to prevent deficiency in healthy people, although coenzyme Q 10 concentrations in tissues decline with age. (oregonstate.edu)
Hyperthyroidism affects about 1% of people in the United States. (msdmanuals.com)

Normally, activation of the CB 1 receptor regulates renal vascular hemodynamics and stimulates the transport of ions and proteins in different nephron compartments. (degruyter.com)

Anatomy12

Organisms11

Diseases49

Chemicals and Drugs51

Analytical, Diagnostic and Therapeutic Techniques and Equipment62

Psychiatry and Psychology8

Phenomena and Processes43

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena8

Technology, Industry, Agriculture1

Humanities1

Information Science8

Named Groups5

Health Care59

Geographicals7

Gestational diabetes7

Diabetic patients7

T1DM2

Group of metabolic disease1

Cardiovascular disease5

Incidence5

Metabolic6

Impaired fasting2

Supplementation3

Prevention4

Microvascular complications1

Clinical10

Obesity and type2

Hyperglycaemia2

Hypertension1

Insulin resistance4

Obese3

Heterogeneous2

Pathogenesis3

Increases3

Cardiac3

Poorly1

Symptoms3

Autoimmunity6

Glycemic control1

Autoimmune1

Disease18

Diagnosis3

Infection2

Significantly2

Fibrosis1

Dysfunction2

20302

Modulation2

Mitochondrial1

Occurs3

Survival1

Risk4

20001

20011

Atypical1

Population2

Common2

Development of diabetes3

Individuals with diabetes1

Globally1

Years4

Therapeutic1

Frequent2

Hyperglycemia3

Functional1

People5

Stimulates1