Types glycolipids. Medical search. Frequent questions

The Glycolipid Cream Cleanser effectively cleanses the skin and removes makeup such as foundation, eyeliner, and mascara. (theordinary.com)

Blood type A has an N-acetylgalactosamine added as the main determining structure, type B has a galactose, and type AB has all three of these antigens. (wikipedia.org)
Antigens which are not present in an individual's blood will cause antibodies to be produced, which will bind to the foreign glycolipids. (wikipedia.org)
Based on the major antigens, blood groups may be classified as one of these four types: Blood is also classified by rhesus (Rh) factor. (feministlawprofessors.com)
Your blood type is considered rare if you lack antigens that 99% of the people are positive for. (feministlawprofessors.com)
There are more than 600 other known antigens, the presence or absence of which creates "rare blood types. (feministlawprofessors.com)
There are two types of natural killer T (NKT) cells, which are both activated by cells presenting specific antigens such as lipids and glycolipids. (cancer.gov)
To assess the frequency of glycolipid complex antibodies in a Western European cohort of patients GBS we used a newly developed combinatorial glycoarray methodology to screen against large range of antigens (11 gangliosides, 8 other single glycolipids and 162 heterodimeric glycolipid complexes). (ox.ac.uk)

Antibodies to the major phenolic glycolipid purified from Mycobacterium leprae have been demonstrated previously in sera of leprosy but not tuberculosis patients using an ELISA. (unboundmedicine.com)
Matreya's monoclonal and polyclonal anti-ganglioside antibodies are directed against the carbohydrate chains of ganglioside and globoside glycolipids. (matreya.com)
This list concerns blood type distribution between countries and regions.Blood type (also called a blood group) is a classification of blood, based on the presence and absence of antibodies and inherited antigenic substances on the surface of red blood cells (RBCs). (feministlawprofessors.com)
Antibodies to heteromeric glycolipid complexes in Guillain-Barré syndrome. (ox.ac.uk)
This study demonstrates that while antibodies against single gangliosides are often found in cases with axonal-type electrophysiology, antibodies against glycolipid complexes predominate in cases with demyelinating electrophysiology, providing a more robust serum biomarker than has ever been previously available for such cases. (ox.ac.uk)
We also examined sera for anti-glycolipid antibodies, a biomarker of GBS, and C jejeunispecific antibodies, a biomarker of C jejeuni exposure. (cdc.gov)
Anti-glycolipid IgG antibodies were more common among male poultry workers as compared to male referents (p = 0.07). (cdc.gov)

We hypothesised that antibody specificities reliant on the cis interactions of neighbouring membrane glycolipids could explain this discrepancy, and would not have been detected by traditional serological assays using highly purified preparations of single gangliosides. (ox.ac.uk)

Glycolipids are lipids with a carbohydrate attached by a glycosidic (covalent) bond. (wikipedia.org)
They can also remove glycans from glycolipids to turn them back into unmodified lipids. (wikipedia.org)
The major polar lipids were phosphatidylglycerol, diphosphatidylglycerol and an unknown glycolipid. (microbiologyresearch.org)
Trehalose glycolipids, consisting of α,α'-trehalose esterified at the 6- and 6'- positions with lipids, exhibit adjuvant activity by binding and activating Macrophage inducible C-type lectin (Mincle). (vuw.ac.nz)

Glycolipid Biosurfactant: A non-stripping surfactant that cleanses and supports the microbiome. (sephora.com)
Evonik received the award for RHEANCE One, a special type of glycolipid biosurfactant derived from renewable raw materials. (inkworldmagazine.com)

TY - JOUR T1 - Analysis of the major antigenic determinants of the characteristic phenolic glycolipid from Mycobacterium leprae. (unboundmedicine.com)
Similarly, PGLs produced by a subset of M. tuberculosis isolates inhibit the host Th1-type T-cell and Mycobacterium cytokine response ( 6 ). (cdc.gov)
Exogenous ligands for Mincle include fungal α-mannose, and the mycobacterial glycolipid, trehalose-6'6'-dimycolate (TDM), also known as cord factor the immunostimulatory component of Mycobacterium tuberculosis [3]. (invivogen.com)
The mycolyltransferase 85A, a putative drug target of Mycobacterium tuberculosis: development of a novel assay and quantification of glycolipid-status of the mycobacterial cell wall. (helmholtz-hzi.de)

Within lysosomes, the enzyme helps break down complexes called glycoproteins and glycolipids, which consist of sugar molecules attached to certain proteins and fats. (medlineplus.gov)

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle. (invivogen.com)
However, the adjuvant activity of trehalose glycolipids could potentially be improved by substituting the ester linkages for more physiologically stable amide bonds. (vuw.ac.nz)
This thesis presents a short protecting group free route to trehalose amide glycolipids, thus allowing for the synthesis of the straight chain glycolipid amides 1a-e in four steps and in excellent (53-61%) overall yields (Figure 1). (vuw.ac.nz)
A second generation of trehalose amide glycolipids, the lipidated brartemicin amide analogues 2a-c, were subsequently synthesised (Figure 1). (vuw.ac.nz)
This report is the first example of trehalose amide glycolipids acting as Mincle agonists, and further studies into the potential of the amides as vaccine adjuvants will be undertaken in due course. (vuw.ac.nz)

The enzymes of the antigen 85 complex (Ag85A, B, and C) possess mycolyltransferase activity and catalyze the synthesis of the most abundant glycolipid of the mycobacterial cell wall, the cord factor. (helmholtz-hzi.de)

Using altered glycolipid ligands, we discovered that the Vb repertoire of iNKT cells impacts recognition and Ag avidity, and that stimulation with suboptimal avidity Ag results in preferential expansion of high-affinity iNKT cells. (ox.ac.uk)

Recent advances in developments of high-mannose type oligosaccharide libraries and structural biology of the carbohydrate-lectin interactions have revealed insights into sugar recognition by those intracellular lectins and the underlying mechanisms of quality control of glycoproteins. (go.jp)
The human genome contains at least 35 genes that encode Golgi sulfotransferases that function in the secretory pathway, where they are involved in decorating glycosaminoglycans, glycolipids, and glycoproteins with sulfate groups. (lu.se)
Although a number of important interactions by proteins such as selectins, galectins, and sialic acid-binding immunoglobulin-like lectins are thought to mainly rely on sulfated O-glycans, our insight into the sulfotransferases that modify these glycoproteins, and in particular GalNAc-type O-glycoproteins, is limited. (lu.se)
Mutations in the NAGA gene interfere with the ability of the alpha-N-acetylgalactosaminidase enzyme to perform its role in breaking down glycoproteins and glycolipids. (medlineplus.gov)

Glycosphingolipids are a subtype of glycolipids containing the amino alcohol sphingosine. (dadamo.com)

The glycolipid is assembled in the Golgi apparatus and embedded in the surface of a vesicle which is then transported to the cell membrane. (wikipedia.org)
The vesicle merges with the cell membrane so that the glycolipid can be presented on the cell's outside surface. (wikipedia.org)
b ) receptors that associate with other tyrosine kinases, and ( c ) tyrosine-kinase-associated receptors with the ligand-binding subunit membrane anchored by a glycolipid, such as that for ciliary neurotrophic factor. (aspetjournals.org)

Since then, progress has been made in the search of prokaryotic glycosyltransferases, increasing the types of enzymes that can be employed in synthesis and modification of sugar chains. (go.jp)

The unmodified antigen, called the H antigen, is the characteristic of type O, and is present on red blood cells of all blood types. (wikipedia.org)
The glycolipid storage gives rise to the characteristic Gaucher cells, macrophages engorged with lipid with a crumpled-tissue-paper appearance and displaced nuclei. (medscape.com)

Mincle is a C-type lectin receptor that has emerged as an important player in innate immunity. (invivogen.com)
C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia. (invivogen.com)
Mincle is a member of the C-type lectin receptor (CLR) family. (invivogen.com)
Amide glycolipids 1a-e were demonstrated to be Mincle agonists with comparable activity to their ester counterparts, as determined using a green fluorescent protein (GFP) reporter cell line assay. (vuw.ac.nz)

This formulation uses a plant-derived glycolipid cleansing agent that cleanses the skin while respecting the skin barrier to maintain hydration. (theordinary.com)

Glycolipids: Glycolipids are biosurfactants, a category of ingredients that work to cleanse the skin by lifting surface level impurities. (sephora.com)

In this study the prevalence of pcaA gene was determined in M. tuberculosis strains typed by spoligotyping. (scielo.br)

Polyglyceryl-6 Dicaprate: Assists in the makeup removal alongside the glycolipids. (sephora.com)

The factors that contribute to neurologic involvement in patients with types 2 and 3 disease are still unknown but may be related to the accumulation of a cytotoxic glycolipid, glucosylsphingosine, in the brain due to the severe deficiency of glucocerebrosidase activity or to neuroinflammation. (medscape.com)
The accumulation of glycolipid causes noncancerous (benign) skin growths (angiokeratomas) to form on the lower part of the trunk. (msdmanuals.com)

Selectins, a class of lectins found on the surface of leukocytes and endothelial cells bind to the carbohydrates attached to glycolipids to initiate the immune response. (wikipedia.org)

The main function of glycolipids in the body is to serve as recognition sites for cell-cell interactions. (wikipedia.org)
Blood types are an example of how glycolipids on cell membranes mediate cell interactions with the surrounding environment. (wikipedia.org)

The essential feature of a glycolipid is the presence of a monosaccharide or oligosaccharide bound to a lipid moiety. (wikipedia.org)
Enzymes called glycosyltransferases link the saccharide to the lipid molecule, and also play a role in assembling the correct oligosaccharide so that the right receptor can be activated on the cell which responds to the presence of the glycolipid on the surface of the cell. (wikipedia.org)
The four main human blood types (A, B, AB, O) are determined by the oligosaccharide attached to a specific glycolipid on the surface of red blood cells, which acts as an antigen. (wikipedia.org)

It is caused by a buildup of glycolipid in tissues. (msdmanuals.com)
In Fabry disease, a glycolipid, which is a product of fat metabolism, accumulates in tissues. (msdmanuals.com)

Retinol-binding protein 4 (RBP4) is closely associated with a variety of abnormal glycolipid metabolism diseases such as insulin resistance, obesity, diabetes mellitus, and metabolic syndrome. (nih.gov)

Enzyme replacement therapy (ERT) is indicated for patients with type 1 and type 3 Gaucher disease who exhibit clinical signs and symptoms of the disease, including anemia, thrombocytopenia, skeletal disease, or visceromegaly. (medscape.com)
The enzyme needed to breakdown the glycolipid, called alpha-galactosidase A, does not work correctly. (msdmanuals.com)
The oral glucosylceramide (glucocerebroside) synthase inhibitor eliglustat, approved by the FDA for treatment of Gaucher disease type 1 (GD1) in August 2014, has proven as effective as intravenous enzyme replacement therapy with imiglucerase. (medscape.com)

The saccharide of the glycolipid will bind to a specific complementary carbohydrate or to a lectin (carbohydrate-binding protein), of a neighboring cell. (wikipedia.org)

An example of how glycolipids function within the body is the interaction between leukocytes and endothelial cells during inflammation. (wikipedia.org)
Glycolipids are also responsible for other responses, notably the recognition of host cells by viruses. (wikipedia.org)
In an emergency, type O negative red blood cells may be given to anyone - especially if the situation is life-threatening or the matching blood type is in short supply. (feministlawprofessors.com)
Type I NKT cells have an immune promoting effect, resulting in tumor cell lysis. (cancer.gov)
Type II NKT cells have an immunosuppressive effect, allowing the tumor cells to survive. (cancer.gov)
While there are various types of T-lymphocytes, NKT cells stand out for a few reasons. (cancer.gov)
Va14Ja18 natural T (iNKT) cells rapidly elicit a robust effector response to different glycolipid Ags, with distinct functional outcomes. (ox.ac.uk)
We have investigated the effects of deoxynojirimycin and its alkylated derivatives on the biosynthesis of glycolipids in HL-60 cells. (ox.ac.uk)
This study examines the potential surface display of this glycolipid by chlamydiae-infected cells and the ability of the GLXA they secrete to associate with the plasma membranes of uninfected cells, a prerequisite for exerting influence on them. (umass.edu)
For example, the size of cells varies according to their types but they are about 1/1000th of a millimeter or smaller. (questionsonislam.com)
There are dozens of types of fat synthesized for a specific purpose in cells. (questionsonislam.com)
Genes Genes are segments of deoxyribonucleic acid (DNA) that contain the code for a specific protein that functions in one or more types of cells in the body or the code for functional ribonucleic. (msdmanuals.com)
A key challenge is to understand how state, but must also afford flexibility in cell-fate choice to permit the different cell-fate options confronting stem and progenitor cell-type diversification and differentiation in response to cells are selected and coordinated such that adoption of a given intrinsic cues or extrinsic signals. (lu.se)

Glycolipids provide energy and serve as markers for cellular recognition. (survivingmesothelioma.com)
Recognition of Tumor Nidogen-1 by Neutrophil C-Type Lectin Receptors. (invivogen.com)

EMAILWIRE.COM, September 21, 2018 ) This report presents the worldwide Residential Smart Smoke Detectors market size (value, production and consumption), splits the breakdown (data status 2013-2018 and forecast to 2025), by manufacturers, region, type and application. (emailwire.com)
This study categorizes the global Glycolipids breakdown data by. (emailwire.com)

The disaccharide, corresponding to the two terminal sugars of the M. leprae glycolipid has been chemically synthesized and shown to inhibit the reaction between glycolipid and antibody in the ELISA. (unboundmedicine.com)

To know the molecular mechanisms, we performed a functional analysis of a C-type lectin receptor, langerin, a molecule that binds L4. (bvsalud.org)

The CD1 molecules are type I glycoprotein with structural similarities to MHC class I and are non-covalently associated with β 2 -microglobulin, belonging to the Ig superfamily. (biolegend.com)

Glycolipids are found on the surface of all eukaryotic cell membranes, where they extend from the phospholipid bilayer into the extracellular environment. (wikipedia.org)
The saccharides that are attached to the polar head groups on the outside of the cell are the ligand components of glycolipids, and are likewise polar, allowing them to be soluble in the aqueous environment surrounding the cell. (wikipedia.org)
Cell surface display of the chlamydial glycolipid exoantigen (GLXA) demonstrated by antibody-dependent complement-mediated cytotoxicity. (umass.edu)
Their developmental cycle is associated with the formation and release of the broadly conserved glycolipid exoantigen (GLXA), which has been implicated in the chlamydial elementary body-host cell interaction. (umass.edu)
The diamino acid in the cell-wall peptidoglycan was ornithine and the peptidoglycan was type B2 β (Glu/Hyg-Gly- d -Orn). (microbiologyresearch.org)
BACKGROUND: This study aimed to investigate the expression and clinical significance of Dendritic cell-associated C-type lectin-1 (Dectin-1) in gastric cancer (GC), and to explore the mechanism of Dectin-1 regulating tumour-associated macrophage (TAM)-mediated immune evasion in GC. (bvsalud.org)

Substrate reduction therapy (SRT) is an alternative treatment for appropriate adult patients with type 1 Gaucher disease. (medscape.com)
Type 1 Gaucher disease is more common among individuals with Ashkenazi Jewish heritage, although all types are panethnic in their distribution. (medscape.com)
Type 1 Gaucher disease is more common among individuals of Ashkenazi Jewish descent, although all 3 types are panethnic in their distribution. (medscape.com)

The major antigenic determinants on this molecule were investigated using antisera raised in rabbits to the purified glycolipid and with a pool of sera from human lepromatous leprosy patients. (unboundmedicine.com)

Glucosylceramide, the accumulated glycolipid, is primarily derived from the phagocytosis and degradation of senescent leukocytes and erythrocyte membranes. (medscape.com)
Glucosylceramide, the accumulated glycolipid, is primarily derived from the phagocytosis and degradation of senescent leukocytes and, to a lesser extent, from erythrocyte membranes. (medscape.com)

Patients with type 3 disease, in addition to organomegaly and bony involvement, present with neurologic involvement, most often including slowing of the horizontal saccadic eye movements. (medscape.com)
In addition to organomegaly and bony involvement, individuals with type 3 disease have neurologic involvement. (medscape.com)

For this reason, people with blood type AB can receive transfusions from all blood types (the universal acceptor), and people with blood type O can act as donors to all blood types (the universal donor). (wikipedia.org)
The donor's blood type must be determined if the blood will be used for transfusions. (feministlawprofessors.com)
Type O is routinely in short supply and in high demand by hospitals - both because it is the most common blood type and because type O negative blood is the universal blood type needed for emergency transfusions and for immune deficient infants. (feministlawprofessors.com)

Now, a new study out of Japan suggests that ganglioside GM2, a surface glycolipid that is overexpressed in a number of cancer types including multiple myeloma, neuroblastoma, and mesothelioma, may offer a way to do that. (survivingmesothelioma.com)

Subtyping is optional for living donors and blood type AB deceased donors. (feministlawprofessors.com)

The Complete Blood Type Encyclopedia is the essential desk reference for Dr. D'Adamo's work. (dadamo.com)
This is the first book to draw on the thousands of medical studies proving the connection between blood type and disease. (dadamo.com)
Studies of human kidneys/urinary tract revealed that human kidney contained a new type of blood group A structure. (gu.se)
ABO blood typing is not sufficient to prove or disprove paternity or maternity. (feministlawprofessors.com)
Each blood type has unique properties. (feministlawprofessors.com)
What is your blood type? (feministlawprofessors.com)
Now that you know how your blood type can help recipients, please schedule an appointment to donate today. (feministlawprofessors.com)
Whole blood is the most flexible type of donation. (feministlawprofessors.com)
If you somehow lack an antigen that 99.99% are positive for, your blood type is extremely rare. (feministlawprofessors.com)
Those with type AB Rh D positive blood are called universal recipients. (feministlawprofessors.com)

Patients with type 1 disease commonly present with painless splenomegaly, anemia, or thrombocytopenia. (medscape.com)
Patients with type 2 disease may present prenatally, at birth or during infancy with increased tone, seizures, strabismus, and organomegaly. (medscape.com)
Failure to thrive, swallowing abnormalities, oculomotor apraxia, hepatosplenomegaly, and stridor due to laryngospasm are typical in infants with type 2 disease. (medscape.com)
ERT sometimes is started in patients with type 2 GD, as often there can be a question regarding disease type and progression, and to delay may have significant impact on patient outcomes. (medscape.com)
There are three types of Schindler disease. (medlineplus.gov)
Schindler disease type I, also called the infantile type, is the most severe form. (medlineplus.gov)
Babies with Schindler disease type I appear healthy at birth, but by the age of 8 to 15 months they stop developing new skills and begin losing skills they had already acquired (developmental regression). (medlineplus.gov)
Schindler disease type II, also called Kanzaki disease, is a milder form of the disorder that usually appears in adulthood. (medlineplus.gov)
Schindler disease type III is intermediate in severity between types I and II. (medlineplus.gov)
Fabry disease occurs when the body lacks enzymes needed to break down a glycolipid. (msdmanuals.com)

CD1c is involved in antigen-presentation of glycolipids. (biolegend.com)

terminated by an aromatic nucleus that is glycosylated by type- or species-specific mono-, tri-, or tetrasaccharide. (cdc.gov)

Anatomy3

Organisms5

Diseases1

Chemicals and Drugs63

Analytical, Diagnostic and Therapeutic Techniques and Equipment9

Phenomena and Processes5

Disciplines and Occupations1

Information Science2

Cream Cleanser1

Antigens7

Antibodies7

Gangliosides1

Lipids4

Biosurfactant2

Mycobacterium4

Complexes1

Trehalose5

Mycobacterial1

Ligands1

Glycoproteins4

Glycosphingolipids1

Membrane3

Synthesis1

Characteristic2

Mincle4

Formulation1

Ingredients1

Tuberculosis1

Dicaprate1

Accumulation2

Immune response1

Interactions2

Oligosaccharide3

Tissues2

Metabolism1

Enzyme3

Carbohydrate1

Cells13

Recognition2

Breakdown2

Inhibit1

Lectin receptor1

Molecules1

Cell6

Gaucher3

Sera1

Primarily2

Neurologic involvement2

Transfusions3

Surface1

Donors1

Blood10

Disease10

Antigen1

Specific1