Cell Deathbeta-Adrenergic Receptor KinasesG-Protein-Coupled Receptor Kinase 2G-Protein-Coupled Receptor KinasesG-Protein-Coupled Receptor Kinase 5G-Protein-Coupled Receptor Kinase 3ApoptosisCause of DeathProtein-Serine-Threonine KinasesProtein KinasesSignal TransductionCell Line, TumorPhosphatidylinositol 3-KinasesCyclic AMP-Dependent Protein KinasesPhosphorylationMAP Kinase Signaling SystemCell SurvivalCaspasesG-Protein-Coupled Receptor Kinase 4G-Protein-Coupled Receptor Kinase 1DeathCell LineProtein Kinase InhibitorsCells, CulturedTumor Necrosis Factor-alphaMolecular Sequence DataEnzyme ActivationTransfectionMutationProtein-Tyrosine KinasesCalcium-Calmodulin-Dependent Protein KinasesCaspase 3NecrosisTime FactorsBlotting, Westernsrc-Family KinasesReceptor Protein-Tyrosine KinasesProto-Oncogene Proteins c-bcl-2Protein Kinase Cp38 Mitogen-Activated Protein KinasesAmino Acid SequenceJNK Mitogen-Activated Protein KinasesTumor Suppressor Protein p53Proto-Oncogene ProteinsCell ProliferationDNA FragmentationMitochondriaRNA, MessengerMice, Inbred C57BLTumor Markers, BiologicalMitogen-Activated Protein Kinase 1AutophagyCell DivisionBase SequenceTumor BurdenDose-Response Relationship, DrugIn Situ Nick-End LabelingReactive Oxygen SpeciesEnzyme InhibitorsMitogen-Activated Protein Kinase KinasesKineticsMitogen-Activated Protein Kinase 3Protein BindingRecombinant ProteinsReceptor, InsulinModels, BiologicalArrestinsCaspase InhibitorsMitogen-Activated Protein KinasesRNA, Small Interferingbcl-2-Associated X ProteinTumor Cells, CulturedAntineoplastic AgentsMice, KnockoutDown-RegulationNeuronsTumor Suppressor ProteinsReverse Transcriptase Polymerase Chain ReactionMAP Kinase Kinase KinasesExtracellular Signal-Regulated MAP KinasesAntigens, CD95Death, Sudden, CardiacCell CycleProtein Structure, TertiaryApoptosis Regulatory ProteinsProto-Oncogene Proteins c-aktGene ExpressionNeoplasmsImmunohistochemistryMembrane ProteinsRecombinant Fusion Proteinsp21-Activated KinasesFlow CytometryGene Expression RegulationCyclin-Dependent KinasesTyrosineMice, TransgenicImmunoblottingNeoplasms, ExperimentalUp-Regulation