Tumors testicular neoplasms. Medical search. Frequent questions

[ 2 ] Adult germ-cell tumors with malignant potential, such as seminoma and embryonal carcinoma, are not present in prepubertal patients. (medscape.com)
Histopathology of the testicle showed both a Sertoli cell tumor and seminoma with invasion of neoplastic Sertoli cells into blood vessels and lymphatics. (acvr.org)
Seminoma: This is a slow-growing form of testicular cancer found in men in their 40s and 50s. (medlineplus.gov)
Evaluation of miR-371a-3p to predict viable germ cell tumor in patients with pure seminoma receiving retroperitoneal lymph node dissection. (harvard.edu)
Patterns of Disease Progression and Outcome of Patients With Testicular Seminoma Who Relapse After Adjuvant or Curative Radiation Therapy. (harvard.edu)
Seminoma is the most common pure germ cell tumor (GCT) of the testis, accounting for up to 50% of cases. (medscape.com)
1] Among mixed GCTs, seminoma is also commonly present in combination with teratoma, yolk sac tumor, and/or embryonal carcinoma. (medscape.com)
Such tumors are still classified as mixed GCT, even if the seminoma is the main component. (medscape.com)
Overall, 60% of germ cell neoplasms have seminoma in their composition, but pure seminomas are genetically different from those that present as a component of a mixed tumor. (medscape.com)
Well-defined associations of seminoma are: cryptorchidism, familial history or a previous testicular GCT, certain intersex syndromes, and oligospermic infertility. (medscape.com)
The mean age at presentation of patients with seminoma is 40 years, which is 5-10 years older than in patients with nonseminomatous testicular tumors. (medscape.com)
During the patient's preoperative MRI, we observed a testicular tumor measuring 2.5 cm that was consistent with the findings of a seminoma. (bvsalud.org)
Histopathological evaluation revealed seminoma of the right testis, nonseminomatous germ cell tumor of the left testis, and metastatic seminoma in the right groin postoperatively. (cancernetwork.com)
The peak incidence is in the third decade of life for non-seminomatous germ cell tumour (NSGCT) and mixed GCT patients, and in the fourth decade for seminoma testis (ST) patients. (uroweb.org)
But fortunately the seminoma type of testicular cancer is quite radiosensitive. (planetayurveda.net)

[ 6 , 7 ] Nistal et al reported frequencies of 49% for yolk-sac tumors, 13% for teratomas, 9% for seminomas and mixed germ-cell tumors, and 29% for sex-cord stromal tumors. (medscape.com)
Gonadal stromal tumors are generally considered significantly less common than germ-cell tumors and primarily include juvenile granulosa-cell tumors, Leydig-cell tumors , and Sertoli-cell tumors. (medscape.com)
Sertoli-cell tumors are the most common gonadal stromal tumors in prepubertal children. (medscape.com)
The two main types of stromal tumors are Leydig cell tumors and Sertoli cell tumors. (medlineplus.gov)
Stromal tumors usually occur during childhood. (medlineplus.gov)
STUDY QUESTION: What is the role of dysregulated transforming growth factor beta (TGFB) signaling in the development of sex cord-stromal tumors in the testis? (tamu.edu)
Unclassified sex cord-stromal tumors (SCSTs) of the testis comprised predominantly of spindle cells can be difficult to classify. (elsevierpure.com)
Renshaw, AA, Gordon, M & Corless, CL 1997, ' Immunohistochemistry of unclassified sex cord-stromal tumors of the testis with a predominance of spindle cells ', Modern Pathology , vol. 10, no. 7, pp. 693-700. (elsevierpure.com)
Testicular myoid gonadal stromal tumors (MGSTs) are rare neoplasms. (bvsalud.org)

We determined Pt-GG and Pt-AG adduct levels by use of 32P-postlabeling after ex vivo cisplatin treatment of fragments of head and neck squamous cell carcinoma (HNSCC) xenografts (five lines), and of tumor biopsies from patients with HNSCC (n = 8) and testicular cancer (n = 8). (nih.gov)
When patient tumor fragments were exposed ex vivo to 80 microM cisplatin for one hour, adduct levels were similar in HNSCC and testicular cancer. (nih.gov)
Persistence of adducts was observed for testicular cancer in the additional drug-free period. (nih.gov)
Maurice-Auguste Chevassu (28 October 1877, in Lons-le-Saunier - 11 July 1957) was a French surgeon and urologist known for his work with testicular cancer. (wikipedia.org)
In regards to surgery for testicular cancer, he doubted the efficacy of simple orchiectomy, instead advocating removal of the testis with its vascular stem, followed by complete removal of associated lymph nodes. (wikipedia.org)
Testicular cancer is cancer that starts in the testicles. (medlineplus.gov)
The exact cause of testicular cancer is poorly understood. (medlineplus.gov)
Testicular cancer is the most common cancer in young and middle-aged men. (medlineplus.gov)
There is no link between vasectomy and testicular cancer. (medlineplus.gov)
Nonseminoma: This more common type of testicular cancer tends to grow more quickly than seminomas. (medlineplus.gov)
Testicular cancer is one of the most treatable and curable cancers. (medlineplus.gov)
Biomarkers in Testicular Cancer: Classic Tumor Markers and Beyond. (harvard.edu)
Tumor markers: value and limitations in the management of cancer patients. (nih.gov)
Tumors or cancer of the TESTIS. (pgscatalog.org)
Cancer testis (CT) antigens are promising candidates for tumor vaccines due to their immunogenicity and tissue-restricted expression. (elsevierpure.com)
This is the first report demonstrating the feasibility of vaccination with a cancer associated epigenetic regulator for the induction of tumor inhibition. (elsevierpure.com)
Due to improved diagnostic tools as well as the establishment of various adjuvant treatment options, the mortality of testicular cancer generally decreased in the last decades. (cancernetwork.com)
However, metastatic bilateral testicular cancer of different histology is a challenging situation for the urologist, which warrants further discussion. (cancernetwork.com)
Testicular cancer is one of the leading cancers affecting younger men in Western countries. (cancernetwork.com)
1] The estimated incidence in the United States for 2009 is about 8,400 cases, and the testicular cancer-related death rate is estimated to be 380. (cancernetwork.com)
To the authors' knowledge, we report the first case of a patient affected by synchronous testicular cancer of different histology. (cancernetwork.com)
This fact puts him into a higher risk group for testicular cancer. (cancernetwork.com)
Testicular cancer is the most common neoplasm among young men aged 15-40 years. (exonpublications.com)
Incidence is increasing worldwide, and some countries, such as Slovenia and the Netherlands, registered a doubling of testicular cancer cases in the last two decades. (exonpublications.com)
Cryptorchidism (undescended testis), which increases the chances of developing testicular cancer by 3.7-7.5 times compared to the general male population, is the only risk factor unanimously recognized. (exonpublications.com)
Despite the increase in incidence, testicular cancer remains a relatively indolent disease with mortality figures substantially unchanged for over three decades. (exonpublications.com)
Substances that cause cancer can be tumor initiators. (doctorlib.info)
The two main types of genes that are now recognized as playing a role in cancer are oncogenes and tumor suppressor genes. (doctorlib.info)
In thyroid cancer cell lines, PATZ1 functioned as a tumor suppressor regardless of p53 status. (oncotarget.com)
Our study demonstrates that PATZ1 knockdown enhances malignant phenotype both in thyroid follicular epithelial cells and thyroid cancer cells, suggesting that PATZ1 functions as a tumor suppressor in thyroid follicular epithelial cells and is involved in the dedifferentiation of thyroid cancer. (oncotarget.com)
Testicular cancer represents 1% of adult neoplasms and 5% of urological tumours, with three to ten new cases per 100,000 males/per year in Western societies [ 6 ]. (uroweb.org)
Testicular cancer has increased during recent decades, predominantly in industrialised countries [ 7 , 8 ], and it continues to rise. (uroweb.org)
The clinical utility of testicular cancer risk loci. (cdc.gov)
Additionally, pets may also be diagnosed with various metastatic or secondary forms of cancer which often originate from another primary tumour elsewhere in their bodies. (myvetspringfieldlakes.com.au)
Tumors or cancer of the LIVER. (lookformedical.com)
Tumors or cancer of the PANCREAS. (lookformedical.com)
Tumors or cancer of the SKIN. (lookformedical.com)
the treatment of bladder cancer, kidney cancer and penis cancer is of high international level, and the therapeutic effect of prostate cancer, testicular neoplasms, pelvic ureteral carcinoma and other diseases is outstanding all over the country, which make our department among the most standardized organizations in treating tumors of male urological and reproductive system. (sysucc.org.cn)
What is testicular cancer? (medlineplus.gov)
Testicular cancer is a cancer that develops in the tissues of one or both testicles. (medlineplus.gov)
Who is most likely to develop testicular cancer? (medlineplus.gov)
Testicular cancer is very rare. (medlineplus.gov)
What are the symptoms of testicular cancer? (medlineplus.gov)
How is testicular cancer diagnosed? (medlineplus.gov)
What are the treatments for testicular cancer? (medlineplus.gov)
Can Testicular Cancer Be Found Early? (medlineplus.gov)
Testicular Microlithiasis: Is It Linked with Testicular Cancer? (medlineplus.gov)
What Causes Testicular Cancer? (medlineplus.gov)
What's New in Testicular Cancer Research? (medlineplus.gov)
Testicular cancer is a condition in which the unusual cell grows out of control in the tissue of one or both of the testes. (planetayurveda.net)
Generally testicular cancer starts with benign neoplasm which then aggressively turns into malignant. (planetayurveda.net)
Around 95% of the males generally survive for around five years after being diagnosed with testicular cancer. (planetayurveda.net)
White men are more prone to testicular cancer. (planetayurveda.net)
It is the most common form of testicular cancer in children but quite rare in adults. (planetayurveda.net)
Cancer limited to testicles and testicular tissues. (planetayurveda.net)
Testicular Cancer Diagnostic. (bookinghealth.com)
The Department of Urology annually examines more than 730 men with suspected testicular cancer. (bookinghealth.com)
Of particular interest is the treatment of malignant urological neoplasms, which include prostate cancer, testicular cancer, kidney and bladder cancer. (bookinghealth.com)
A patient is considered to have a cancer of unknown primary origin when cancer is detected at one or more sites and routine evaluation fails to identify the primary tumor. (msdmanuals.com)
These changes have been predicted by cancer epidemiologists for many years, but even they are surprised by the speed at which these changes are occurring, e.g., the emergence of cancer of the breast, colon and prostate in several countries in which these neoplasms were hardly known only 20 to 30 years ago. (who.int)
6XUYLYDO RI FDQFHU SDWLHQWV Survival data allow the calculation of the prevalence of organ-specific neoplasms in a given country and provide a basis for national cancer control strategies to be pursued in collaboration with the WHO programme on cancer control. (who.int)
Intra-tumour IgA1 is common in cancer and is correlated with poor prognosis in bladder cancer. (lu.se)
Patients with breast, cervical, ovarian and testicular cancer, lymphoma, and brain tumors were identified in national quality registries. (lu.se)
The data presented in this edition of Cancer Incidence in Five The CI5 data include all invasive malignant neoplasms and Continents (CI5) are mainly organised according to anatomical some non-invasive malignant neoplasms For most morphology site However, for some sites, the histological type of cancer codes, a fifth digit /1 or /2 automatically excludes the data entry. (who.int)
Other specified malignant neoplasm (Other specified cancer tumour Other codes are obsolete, ie the entities have been in the previous edition). (who.int)
More than half of patients with testicular cancer treated with first-line cisplatin-based chemotherapy in a recent study developed hearing loss (HL) or tinnitus. (medscape.com)
For their study, Sanchez and colleagues enrolled cisplatin-treated testicular cancer survivors at eight cancer centers between 2012 and 2018. (medscape.com)
Testicular cancer (TC) is one example, with a median diagnosis age of only 30 years, and with TC the leading malignancy among men age 20-39 years. (medscape.com)
CHICAGO - A substantial percentage of testicular cancer survivors have low testosterone levels, which in turn puts them at risk for a plethora of chronic health conditions, including hypertension , diabetes, erectile dysfunction , anxiety , and depression , according to findings from a large multicenter study. (medscape.com)
Testicular cancer occurs at a young age and is highly curable, and patients can expect to live for 40 years after their diagnosis, but there is a long-term risk for late complications from treatment," said lead study author Mohammad Issam Abu Zaid, MBBS, an assistant professor of medicine at the Indiana University School of Medicine in Indianapolis. (medscape.com)
Clinical and genetic factors can increase the risk for hypogonadism, and providers should screen testicular cancer survivors for hypogonadism and treat those with symptoms," he said. (medscape.com)
As previously reported by Medscape Medical News, survivors of testicular cancer face a worrisome risk of developing certain metabolic effects, such as hypertension, that are tied to platinum-based chemotherapy. (medscape.com)
Although it's been known for some time that low testosterone levels occur in a significant proportion of survivors of testicular cancer, the current study is one of the first to examine its relationship with long-term health complications in North American patients. (medscape.com)
One European study , for example, reported that the prevalence of metabolic syndrome was higher among survivors of testicular cancer who were homozygous for a single-nucleotide polymorphism (SNP), rs523349 (V89L), in 5-α-reductase gene ( SRD5A2 ). (medscape.com)
In the current study, Dr Zaid and his colleagues evaluated the first 491 patients who are participants in the Platinum Study, which aims to be the largest study of survivors of testicular cancer worldwide. (medscape.com)
SHBG polymorphisms appear important in survivors of testicular cancer, but the study was underpowered to confirm an association, Dr Zaid commented. (medscape.com)
Our findings underscore the need for clinicians to assess testicular cancer for physical signs or symptoms of hypogonadism and to measure testosterone in those who do," he concluded. (medscape.com)

It has many synonyms like endodermal sinus tumor, infantile embryonal carcinoma and orchid blastoma. (planetayurveda.net)
Similarly, under Carcinoma, specific renamed or deleted in later revisions of tumour classifications. (who.int)

Here he explains two dominant types of testicular neoplasms. (wikipedia.org)
While past research has detailed the pathological characteristics of these tumors, the radiological differences between MGST and other types of testicular tumors have not been elucidated. (bvsalud.org)

According to recent reports, testis preserving surgery has become a serious option in the treatment of benign testicular tumours. (pediatriconcall.com)
Other less common forms include hemangiosarcomas (blood vessel wall tumours), mammary gland tumours, soft tissue sarcomas, and testicular neoplasms. (myvetspringfieldlakes.com.au)
Significant differences in survival were revealed when comparison was made with developing countries, for people with cancers that can be successfully treated by chemotherapy (malignant lymphomas, leukaemia, testicular tumours) and modest differences for neoplasms that can be cured by early detection and surgical intervention. (who.int)
An introduction to the WHO 5th edition 2022 classification of testicular tumours. (who.int)

The most common germ-cell tumors are yolk-sac tumors and teratomas, which were reported by Ross to account for about 62% and 26% of testis tumors, respectively. (medscape.com)
Ross JH, Rybicki L, Kay R. Clinical behavior and a contemporary management algorithm for prepubertal testis tumors: a summary of the Prepubertal Testis Tumor Registry. (pediatriconcall.com)
Ross JH, Kay R. Prepubertal testis tumors. (medscape.com)
Thomas JC, Ross JH, Kay R. Stromal testis tumors in children: a report from the prepubertal testis tumor registry. (medscape.com)
Recently Described and Clinically Important Entities in Testis Tumors: A Selective Review of Changes Incorporated Into the 2016 Classification of the World Health Organization. (nih.gov)

Thus, testicular teratoma should be considered in any child with painless inguino-scrotal swelling. (pediatriconcall.com)
Experience with testis-sparing surgery for testicular teratoma. (pediatriconcall.com)
Carver BS, Ahmadie HA, Sheinfeld J. Adult and Paediatric testicular teratoma. (pediatriconcall.com)

Many patients with extragonadal germ cell tumors have histories of infertility, and testicular biopsy in these patients shows various abnormalities, including decreased spermatogenesis, peritubular fibrosis, and interstitial edema. (health.am)
Epidemiological risk factors for TC are components of the testicular dysgenesis syndrome, which encompasses cryptorchidism, hypospadias, decreased spermatogenesis and impaired fertility [ 11-13 ] or disorders/differences of sex development [ 14 ]. (uroweb.org)

Therefore, patients can be safely managed with observation after orchiectomy followed by chemotherapy for recurrent tumors. (medscape.com)
[ 14 ] Retroperitoneal lymph node dissection is reserved for children with persistent retroperitoneal lymphadenopathy or increased serum tumor markers after orchiectomy and chemotherapy. (medscape.com)
Recently suggested associations include high estrogen levels, previous radiotherapy or chemotherapy, exposure to organochlorine,[11] abusive use of marijuana,[12] testicular microlithiasis, and nutrition status during infancy, but these reports lack confirmation. (medscape.com)
They generally present in the form of a single tumor but if they spread they do not respond well to chemotherapy. (planetayurveda.net)

Substances that increase the risk of NEOPLASMS in humans or animals. (lookformedical.com)

In human literature, detection of the 'whirl' sign is a reliable method for diagnosing testicular torsion in pediatric and adult males, and the 'whirl' sign has been reported in a dog with torsion of a cryptorchid testicular neoplasm on computed tomography previously. (acvr.org)
Follow-up schedules should include computed tomography imaging during the first 3 years, long-term measurement of tumor markers, and mechanisms for patients to be seen promptly should symptoms of tumor recurrence occur. (ox.ac.uk)

The serum tumor markers were within the normal range. (bvsalud.org)
In general, serum tumor markers are characterized by low sensitivity and low specificity. (doctorlib.info)

[ 13 ] Alpha-fetoprotein (AFP) can be used as a reliable tumor marker because levels are increased in more than 90% of yolk-sac tumors. (medscape.com)
6) Testis preserving surgery should be reserved for testicular tumor proved to be benign by normal level of serum alpha-fetoprotein and frozen biopsy report. (pediatriconcall.com)
They increase the tumor marker protein called alpha fetoprotein as well as HCG. (planetayurveda.net)
This type also increases the alpha fetoprotein levels in tumors. (planetayurveda.net)
Immunoperoxidase staining of tumor cells for alpha-fetoprotein or beta- human chorionic gonadotropin may suggest readily treatable germ cell tumors. (msdmanuals.com)

Given history, a Sertoli cell tumor is the primary differential diagnosis, with other testicular neoplasms considered less likely. (acvr.org)
In this case, a 'whirl' sign was appreciated, further supporting a diagnosis of testicular torsion. (acvr.org)
Less frequently, a tubular morphology can be seen (see the images below), posing a differential diagnosis with Sertoli cell tumor. (medscape.com)
Testicular tumors: oncologic imaging and diagnosis. (nih.gov)
Pitfalls in Diagnosis and Management of Testicular Choriocarcinoma Metastatic to the Brain: Report of 2 Cases and Review of Literature. (nih.gov)
This paper offers consensus recommendations for imaging of pediatric patients with a known or suspected primary testicular malignancy at diagnosis and during follow-up. (elsevierpure.com)
Differential diagnosis of nonpalpable testicular lesions: qualitative and quantitative contrast-enhanced US of benign and malignant testicular tumors. (ox.ac.uk)
PurposeTo evaluate the diagnostic accuracy of unenhanced and quantitative contrast-enhanced ultrasonography (US) in the differential diagnosis of small nonpalpable testicular lesions.Materials and methodsThe local review board approved the protocol, and all patients provided written informed consent. (ox.ac.uk)
Quantitative scrotal contrast-enhanced US is a noninvasive diagnostic tool that could improve the differential diagnosis and individualized management of small testicular lesions. (ox.ac.uk)

The association of Klinefelter syndrome and mediastinal nonseminomatous germ cell tumors is now well recognized. (health.am)
Hematologic Neoplasia A unique association between mediastinal nonseminomatous germ cell tumors and a variety of hematologic neoplasms is now well described. (health.am)
All hematologic neoplasms developed in the 287 patients with mediastinal nonseminomatous germ cell tumors, for a 2% incidence in this group. (health.am)
However, the specific association of leukemias and other hematologic neoplasms with mediastinal nonseminomatous germ cell tumors, rather than with all germ cell tumors, remains unexplained. (health.am)
In addition to hematologic neoplasia, several cases of idiopathic thrombocytopenia in association with mediastinal nonseminomatous germ cell tumors have been reported. (health.am)
Risk stratification of pubertal children and postpubertal adolescents with clinical stage I testicular nonseminomatous germ cell tumors. (medscape.com)

Testicular tumors account for 1-2% of all pediatric tumors, with an incidence of 0.05-2 per 100,000 children. (medscape.com)
Pediatric prepubertal testicular tumors are dramatically different from adult neoplasms. (medscape.com)
Pediatric testicular tumors: contemporary incidence and efficacy of testicular preserving surgery. (medscape.com)

Forty-four of the 115 patients (38%) had malignant tumors, 42 had benign tumors (37%), and 29 (25%) had nonneoplastic lesions. (ox.ac.uk)
Rare malignant tumors require resection, as well as, possibly, adjunctive therapy and referral to an oncologist. (medscape.com)
20years diagnosed with malignant tumors during 2003-2019. (cdc.gov)

Ultrasonogram in an infant revealing a heterogeneous intratesticular mass that proved to be a juvenile granulosa-cell tumor. (medscape.com)

Seminomas and mixed germ-cell tumors are extremely rare in prepubertal children. (medscape.com)
Most authorities believe that seminomas should be managed as in adults and mixed germ-cell tumors should be treated according to the most malignant subtype present. (medscape.com)
Specifically, cryptorchid testicles have an increased risk of developing seminomas and Sertoli cell tumors. (acvr.org)
Sertoli cell tumors and seminomas rarely exhibit regional or distant metastasis, though local invasion is common. (acvr.org)
Differences in behavior and clinical outcome suggest that mediastinal seminomas are biologically different from gonadal seminomas and can develop de novo without a testicular primary focus. (medscape.com)
In contrast, tumors arising in the retroperitoneum are virtually always associated with premalignant lesions in one of the testes and behave clinically similar to metastatic testicular seminomas. (medscape.com)
To investigate further the potential role of mutated protein kinases in the development of TGCT and to characterize the prevalence and patterns of point mutations in these tumors, we have sequenced the coding exons and splice junctions of the annotated protein kinase family of 518 genes in a series of seven seminomas and six nonseminomas. (ox.ac.uk)
These germ cell tumors are divided into seminomas and nonseminomas. (planetayurveda.net)

1) The reported incidence of testicular tumor in children ranges from 0.5-2.0 cases per 100,000 boys as against 5.4 cases per 100,000 men. (pediatriconcall.com)

Staining for S-100 protein and smooth muscle actin was also observed in three of six granulosa cell minors and both juvenile granulosa cell tumors. (elsevierpure.com)
Juvenile granulosa cell tumors of the testis: a clinicopathologic study of 70 cases with emphasis on its wide morphologic spectrum. (medscape.com)

Finally, we propose a general framework of male germ cell tumor pathology that accounts for their mutational landscape, timing and cellular origin. (prinsesmaximacentrum.nl)
Ki-67 assessment of pancreatic neuroendocrine neoplasms: Systematic review and meta-analysis of manual vs. digital pathology scoring. (who.int)

Testicular choriocarcinoma: a rare variant that requires a unique treatment approach. (nih.gov)
and human chorionic gonadotropin (hCG), seen in choriocarcinoma testicular germ cell neoplasms. (doctorlib.info)

Tallen G, Hernáiz Driever P, Degenhardt P, Henze G, Riebel T. High reliability of scrotal ultrasonography in the management of childhood primary testicular neoplasms. (medscape.com)

The 2022 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs-Part B: Prostate and Urinary Tract Tumors. (who.int)

Tumor markers are substances that can be detected in the peripheral blood and are derived from neoplastic populations, but lack functional hormonal or other physiologic activity. (doctorlib.info)

In 1906 he published Tumeurs du testicule (tumors of the testis), a book in which he provides a thorough categorization of testicular cancers. (wikipedia.org)
The disease-free survival rate for Stage II and III cancers is slightly lower, depending on the size of the tumor and when treatment is begun. (medlineplus.gov)
Tumors or cancers of the KIDNEY. (lookformedical.com)
Most of the testicular cancers arise from germinal cell tumors and spread rapidly. (planetayurveda.net)
Family history of testicular cancers. (planetayurveda.net)
Greater than 95%of testicular cancers start with germ cells. (planetayurveda.net)

The average age of patients with Klinefelter syndrome who develop extragonadal germ cell tumors is approximately 18 years, 10 years younger than the median age of those developing this tumor in the absence of Klinefelter syndrome. (health.am)
In addition, patients who are successfully treated for extragonadal germ cell tumors have a markedly increased risk of developing a subsequent testicular germ cell tumor. (health.am)
These data suggest that either a congenital or an acquired germ cell defect contributes not only to defective spermatogenesis but also to the development of extragonadal germ cell tumors. (health.am)
In a series of 635 patients with extragonadal germ cell tumors, 17 patients developed hematologic malignancies at a median of 6 months after the extragonadal germ cell tumor was diagnosed. (health.am)
Extracranial and extragonadal germ cell tumors and melanoma were both significantly decreasing. (cdc.gov)

[ 9 ] A descriptive analysis of prepubertal testicular germ-cell tumors from a large Chinese center cited frequencies of 50.9% for teratomas, 29.2% for yolk-sac tumors, 19.3% for epidermoid cysts, and 0.6% for mixed germ-cell tumors. (medscape.com)
[ 10 ] However, in tumor registries, yolk-sac tumors have been more common than teratomas, though it is possible that this may reflect a reporting bias. (medscape.com)
The vast majority (85%) of yolk-sac tumors in children present as clinical stage I disease, compared with only 35% in adults. (medscape.com)
2) Childhood testicular tumors are more likely to be benign and have lower incidence of metastasis (2) and are the second most common testicular tumour in children after yolk sac tumor. (pediatriconcall.com)
3) The reported high prevalence rates of the prepubertal yolk sac tumor probably results from a reporting bias, since benign tumors are less likely to be submitted to the tumor registries. (pediatriconcall.com)
Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases. (medscape.com)
These tumors look like a yolk sac of early human embryos. (planetayurveda.net)

Polymorphisms of KITLG, SPRY4, and BAK1 genes in patients with testicular germ cell tumors and individuals with infertility associated with AZFc deletion of the Y chromosome]. (cdc.gov)

The 2016 update of the World Health Organization (WHO) classification of testicular germ-cell tumors divided them into two broad categories on the basis of whether they are derived from a precursor lesion: germ-cell neoplasia in situ (GCNIS). (medscape.com)

Some series have suggested that teratomas, which most believe are vastly underreported because of their benign nature, may account for almost 50% of prepubertal testicular tumors. (medscape.com)
Prepubertal testicular tumor: Actual prevalence rate of histological types. (pediatriconcall.com)
Prepubertal testicular tumors: a 20-year experience with 40 cases. (medscape.com)

Although variable staining for S-100 protein was found in 5 of the 12 other SCSTs (4 Leydig cell, 6 Sertoli-Leydig cell, and 2 unclassifiable ovarian SCSTs), reactivity for smooth muscle actin was present in only 1 Sertoli-Leydig cell tumor. (elsevierpure.com)

Because the most common causative primary tumors are those of the testes, lungs, colon and rectum, and pancreas, examination of these areas must be thorough. (msdmanuals.com)

The hemangioma, Lymphangiomas and cystic hygroma in children, are the widespread benign neoplasm. (benthamscience.com)

5) Inguinal orchiectomy has traditionally been the gold standard of treatment for testicular tumors in childhood. (pediatriconcall.com)

The abnormal growth of cells like primary or metastatic masses in the head and neck, thyroid and parathyroid lesions, or the traumatic injuries of the head and neck represents malignant neoplasm. (benthamscience.com)

Overall, it is a rare malignancy and represents about 1% of the adult neoplasms and 5% of urological tumors. (exonpublications.com)
The surgical method has become a major urological neoplasm operation for doctorsfrom all provinces to learn and then perform in their local areas. (sysucc.org.cn)
The surgical method has become a major urological neoplasm operation for doctors from all provinces to learn and then perform in their local areas. (sysucc.org.cn)

Testicular and ovarian atrophy was also seen in mice. (cdc.gov)

Prostatic histopathology revealed squamous metaplasia secondary to feminization syndrome from the Sertoli cell tumor. (acvr.org)

Testicular neoplasms in infants and children are rare, representing 1% of all paediatric solid tumors and 3% of testicular tumors. (pediatriconcall.com)

Immunohistochemical Expression of Preferentially Expressed Antigen in Melanoma (PRAME) in the Uninvolved Background Testis, Germ Cell Neoplasia In Situ, and Germ Cell Tumors of the Testis. (harvard.edu)

Four of 22 consecutive patients (18%) treated at Indiana University for primary mediastinal germ cell tumors had karyotypic confirmation of Klinefelter syndrome, and an additional patient had clinical features. (health.am)
In dogs diagnosed with testicular neoplasia, anywhere from 4-20% of cases will have multiple primary tumors, as seen in this case. (acvr.org)
Primary intratesticular tumors are uncommon in children, but incidence and risk of malignancy both sharply increase during adolescence. (elsevierpure.com)
A 36-year-old male presented to his primary care practitioner with bilateral testicular swelling. (cancernetwork.com)
A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
Increasing numbers of immunocytochemical stains can be used to test available cancerous tissue to help determine the primary site and can potentially identify tumors arising from the lung, colon, or breast. (msdmanuals.com)

thus, tumors with a high cell turnover are most susceptible (certain leukemias and lymphomas, small proliferating tumors, "recruited" tumor cells, and micrometastases). (doctorlib.info)
In addition, immune peroxidase staining for immunoglobulin, chromosome studies, and immunophenotyping may help diagnose the various subtypes of malignant lymphomas, which may be difficult to recognize and differentiate from other tumors (even carcinomas) outside lymph nodes. (msdmanuals.com)

Anatomy1

Diseases21

Chemicals and Drugs7

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Phenomena and Processes2

Seminoma15

Stromal tumors9

Cancer77

Carcinoma2

Types of testicular2

Tumours4

Testis tumors5

Teratoma3

Decreased spermatogenesis2

Chemotherapy4

Humans1

Computed tomography2

Serum tumor markers2

Alpha fetoprotein5

Diagnosis9

Nonseminomatous germ6

Pediatric3

Malignant tumors3

Granulosa Cell1

Seminomas8

Incidence of testicular1

Juvenile granulosa-cell tumors2

Pathology2

Choriocarcinoma2

Ultrasonography1

20221

Markers1

Cancers6

Extragonadal germ cell t5

Yolk-sac7

Patients with testicular1

Classification of testicular1

Prepubertal testicular3

Leydig Cell1

Testes1

Benign neoplasm1

Orchiectomy1

Metastatic1

Urological3

Ovarian1

Sertoli Cell1

Solid tumors1

Germ-cell neoplasia in situ1

Primary6

Lymphomas2