MutationTumor Suppressor Protein p53Tumor Suppressor ProteinsDNA Mutational AnalysisGenes, Tumor SuppressorVon Hippel-Lindau Tumor Suppressor ProteinCell Line, TumorTumor Suppressor Protein p14ARFRetinoblastoma ProteinPoint MutationProto-Oncogene Proteins c-mdm2Mutation, MissenseMolecular Sequence DataGenes, p53Base SequenceCell LineProtein BindingDNA-Binding ProteinsTumor Markers, BiologicalGene Expression Regulation, NeoplasticNuclear ProteinsTransfectionTranscription FactorsApoptosisAmino Acid SequenceNeurofibromin 2Adenomatous Polyposis Coli ProteinCell CycleSignal TransductionCell Transformation, NeoplasticTumor BurdenProto-Oncogene ProteinsPromoter Regions, GeneticCell ProliferationTumor Necrosis Factor-alphaCyclin-Dependent Kinase Inhibitor p16Genes, SuppressorNeoplasm ProteinsPTEN PhosphohydrolaseUbiquitin-Protein LigasesNeoplasmsCell DivisionRNA, MessengerCell Cycle ProteinsTumor Cells, CulturedCyclin-Dependent Kinase Inhibitor p21Transcription, GeneticPhosphorylationWilms TumorProtein Structure, TertiaryBlotting, WesternProteinsRepressor ProteinsDown-RegulationDNA DamagePolymerase Chain ReactionReverse Transcriptase Polymerase Chain ReactionBinding SitesLigasesCyclinsTranscriptional ActivationNeoplasms, ExperimentalKidney NeoplasmsSuppression, GeneticGene DeletionCarrier ProteinsFrameshift MutationDNA, NeoplasmE2F Transcription FactorsLoss of HeterozygosityDNA PrimersCells, CulturedGerm-Line MutationGene SilencingProtein-Serine-Threonine KinasesRecombinant Fusion ProteinsDNA MethylationFibroblastsGene Expression RegulationImmunohistochemistryHeLa CellsRNA, Small InterferingBreast NeoplasmsMembrane ProteinsRNA InterferenceAdenocarcinomaBrain NeoplasmsPhenotypeMice, Inbred C57BLE2F1 Transcription FactorCell NucleusTrans-ActivatorsExonsDNAMice, NudeWT1 ProteinsTransplantation, HeterologousAllelesCarcinoid TumorRecombinant Proteins