Tumor markers biological. Medical search. Frequent questions

CTCs, like the tumors they are originally detached from, lack unique and well-defined universal biomarkers highlighting the challenges of detection specificity," reports Dr. Shaun Zhang, M.D. Anderson Professor of biology and biochemistry and director of the Center for Nuclear Receptors and Cell Signaling. (uh.edu)
they can also serve as potential biomarkers and therapeutic targets for tumors, as demonstrated in multiple studies [ 7 ]. (hindawi.com)
But in practice, immunotherapies have largely advanced either without any companion diagnostic biomarkers, or with specific, single-parameter tests that gauge PD-L1 expression, microsatellite instability, or tumor mutational burden (TMB) - all of which are recognized as capturing only some of the variability in immunotherapy response, and as such, potentially missing responders or mistakenly identifying non-responders. (genomeweb.com)

As one of the most prevalent types of malignant tumors, lung cancer has been ranked among the highest incidence and mortality rates in many parts of the world [ 1 ]. (biomedcentral.com)
It was reported that Ki67 (a significant marker for malignant tumors) Labeling Index value ranged from 2% to 40% in BOT specimens [3]. (researchsquare.com)
Permissive histologic interpretation may result in the designation of some non-neoplastic Hürthle cell lesions as malignant tumors. (medscape.com)

And TMB has been shown to associate with response across many tumor types, resulting in the recent histology-agnostic US Food and Drug Administration approval of pembrolizumab (Merck's Keytruda) as a treatment for adult and pediatric patients with refractory solid tumors and a high mutational burden. (genomeweb.com)

2004). "Testicular tumor markers: Corner-stones in the management of malignant germ cell tumors" (PDF). (wikipedia.org)
Markers have been most helpful in the workup of patients with germ cell tumors. (medscape.com)
In addition to their histologic characteristics, germ cell tumors retain molecular characteristics of their primordial lineage. (medscape.com)
Other biological markers for germ cell tumors include lactate dehydrogenase isoenzymes and placental alkaline phosphatase, although these are less specific. (medscape.com)
AFP is a glycoprotein produced by fetal yolk sac elements and is produced by a wide range of cancers , including gastric , liver, and colon adenocarcinoma , as well as extracranial germ cell tumors. (medscape.com)
Non-germ cell tumors can derive from pineal parenchymal cells, as well as from surrounding tissue. (medscape.com)

This study aimed to evaluate the effect of clinicopathologic and surgical factors on the prognosis and fertility outcomes of patients with borderline ovarian tumour (BOT). (researchsquare.com)

Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm. (reference.md)
Novel mass spectrometry (MS) imaging techniques are now revealing the importance of these changes in tumour progression and assisting in cancer biomarker discovery. (ddw-online.com)
At the pathological level, changes in glycosylation and their importance in tumour progression have been well documented over time but, until now, have not been effectively demonstrated and localisation has not been achieved. (ddw-online.com)
We hypothesized that the acquisition of cancer stem cells (CSC), a subpopulation that drive tumor initiation and progression, may contribute to CNT carcinogenesis. (cdc.gov)

On the other hand, in brain tumors, such as glioma and glioblastoma, CSCs have instead been identified using cell surface markers, including SSEA-1 20 , EGFR 21 , and CD44 22 . (atlasantibodies.com)

Anticipated technological breakthroughs will create numerous opportunities for determining genetic predisposition, detecting specific tumors, and monitoring biological response to cancer therapy. (aarkstore.com)
Although the type of tumor cannot be determined reliably from the radiographic characteristics alone, some patterns are associated with specific tumors. (medscape.com)

This CLIA kit applies to the in vitro quantitative determination of Human CA724 concentrations in Serum, plasma and other biological fluids. (caslab.com)
These include autoantibodies, circulating tumour DNA, serum based tumour markers and nasal epithelial transcriptomics. (southampton.ac.uk)
Measurements of serum and CSF tumor markers are a valuable component of the preoperative evaluation. (medscape.com)
ABSTRACT The value of serum tumour markers in the prognosis of patients with breast cancer is controversial. (who.int)
Imaging studies in- was one of the first serum-based tu- The study sample was women with cluding chest X-rays, liver ultrasonog- mour markers to be characterized, primary breast cancer attending a pri- raphy and bone scans were performed and its utility has been assessed in vate clinic in Yazd, Islamic Republic if there was clinical or laboratory a variety of malignancies including of Iran. (who.int)

The Center for Nuclear Receptors and Cell Signaling at the University of Houston has developed a new way to detect very rare and highly heterogeneous circulating tumor cells with high specificity and sensitivity. (uh.edu)
Circulating tumor cells, which are detached from primary tumors to enter the bloodstream, are particularly hard to detect. (uh.edu)
Dr. Shaun Zhang, M.D. Anderson Professor of biology and biochemistry and director of the Center for Nuclear Receptors and Cell Signaling, invented the UniPro which finds rare circulating tumor cells. (uh.edu)
Unambiguously detecting live circulating tumor cells opens the door for many clinical applications, such as convenient and instantaneous monitoring of the effectiveness of clinical cancer treatment and monitoring cancer relapse. (uh.edu)
Protein markers commonly used for circulating tumor cells investigations. (medscape.com)

Biological changes during breast cancer recurrence should be given careful clinical consideration because they affect treatment after recurrence. (biomedcentral.com)
sis in primary breast cancer patients, toms of metastasis or recurrence and Tumour markers assays with elevated levels reflecting adverse with no other malignant disorders. (who.int)

Although Hürthle cell carcinoma was previously considered a variant of follicular cell neoplasms, which are generally less aggressive, the 2017 World Health Organization (WHO) classification of endocrine tumors reclassified it as a distinct entity. (medscape.com)

The cancer diagnostics market is on the verge of explosion, as the researchers approach major technological breakthroughs in tumor diagnosis and therapy, discover new specific antigens, and unlock the mystery of the genetic basis of the disease. (aarkstore.com)
In contrast, most markers (CD3, CD5, CD13, CD14, CD19, CD45, HLA-DR, and TdT) showed strong correlation between PB and BM samples in AML group.Conclusions:The findings of this study suggests that targeted gating strategy for blast population as well as selection of a suitable panel of monoclonal antibodies may be essential for diagnosis of leukemia resulting in similar immunotyping pattern in PB and BM. (medscimonit.com)
Our findings suggest an important contribution of tumor markers in the diagnosis and prognosis of these malignancies, as well as in treatment planning. (bvsalud.org)
Diagnosis of malignant pleural effusion with combinations of multiple tumor markers: A comparison study of five machine learning models. (cdc.gov)
Neither of these proteins has proven valuable in the diagnosis of pineal parenchymal cell tumors. (medscape.com)

Colorectal cancer (CRC) is characterized by high rates of proliferation and metastasis and represents the third most common form of malignant tumor and the fourth leading cause of mortality in the world, thus creating a serious threat to health [ 1 ]. (hindawi.com)
circITGA7 serves as a tumor suppressor in CRC by inhibiting growth and metastasis by suppressing the Ras signaling pathway [ 8 ]. (hindawi.com)
Cancer stem cells (CSCs) are small cells, 1% to 3% of all cells in a tumor, that drive the tumor's initiation, growth, and metastasis and may cause relapse. (atlasantibodies.com)
Overall, only about 33% of Hürthle cell tumors demonstrate signs of that invasive growth that indicates malignancy and the possibility of metastasis. (medscape.com)

Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. (reference.md)

CSCs were first identified in hematological cancer such as acute myeloid leukemia in the late '90s when scientists isolated a subpopulation of leukemia cells that expressed the surface marker CD34 but not CD38. (atlasantibodies.com)
The authors established that this CD34+/ CD38− subpopulation was capable of initiating tumors 3 . (atlasantibodies.com)
Relapse after cancer treatment is often attributed to the persistence of a subpopulation of tumor cells known as cancer stem cells (CSCs), which are characterized by their remarkable tumor-initiating and self-renewal capacity. (bvsalud.org)

18-21 These vegetables are known for their characteristic (and eye-irritating) organosulfur compounds, which slow tumor growth and kill cancer cells. (drfuhrman.com)
In one fascinating study, women were given flaxseeds daily after being diagnosed with breast cancer and reduced growth and increased death of their tumor cells was found after just 4-5 weeks. (drfuhrman.com)
Current methods of detecting CTCs mainly rely on immunological detection of protein markers on the tumor cells. (uh.edu)
First, when tumor cells get into the blood, they intend to undergo a biological change called epithelial-mesenchymal transition (EMT). (uh.edu)
Many neoplasm proteins have been characterized and are used as tumor markers (TUMOR MARKERS, BIOLOGICAL) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. (reference.md)
In this present study, we found that circIFT80 was abnormally overexpression in colorectal cancer tissues and tumor cells. (hindawi.com)
This section also includes a Table of 'Notable Biological Product Patents' spanning almost 100 years between 1903 (adrenaline) and 2001 (human embryonic stem cells) as well as a Table on Supreme Court and other opinions addressing the patent-eligibility question. (patentdocs.org)
Direct comparison study of DNA methylation markers in EpCAM-positive circulating tumour cells, corresponding circulating tumour DNA, and paired primary. (oncotarget.com)
Circulating Tumour Cells (CTCs) and circulating tumour DNA (ctDNA) represent a non-invasive liquid biopsy approach for the follow-up and therapy management of cancer patients. (oncotarget.com)
Circulating Tumour Cells (CTCs) and circulating tumour DNA (ctDNA) are the major players in liquid biopsy analysis, since they can both provide an alternative approach that enables a sensitive, dynamic and specific serial tumour sampling during the course of treatment, and an early marker of response to systemic therapy [ 1 - 3 ]. (oncotarget.com)
Among all cancerous cells, a few act as stem cells that reproduce and sustain the tumor, much like stem cells normally renew and sustain our organs and tissues. (atlasantibodies.com)
The use of CD133 (PROM1) to identify CSCs in glioma is still in question because tumorigenic cells are equally found in both CD133+ and CD133− cells in some gliomas, while some CD133+ brain tumor cells may not possess tumor-initiating capacity 23 . (atlasantibodies.com)
These clinical observations are consistent with the demonstration of receptors for VEGF (VEGFR1 and VEGFR2) in tumour proximal endothelial cells 15 along with the frequent (40-75%) expression of VEGF (particularly VEGFA) in BTC 9-, 11 particularly at the invasive edge of the tumour. (nature.com)
Chronic SWCNT-exposed cells were evaluated for the presence of CSC-like cells under CSC-selective conditions of tumor spheres and side population (SP). (cdc.gov)
CSC-like cells were isolated using fluorescence-activated cell sorting and were assessed for aggressive behaviors, including acquired apoptosis resistance and increased cell migration and invasion in vitro, and tumor-initiating capability in vivo. (cdc.gov)
These CSC-like cells, in contrary to their non-CSC counterpart, possessed all biological features of lung CSC that are central to irreversible malignant transformation, self-renewal, aggressive cancer behaviors, and in vivo tumorigenesis. (cdc.gov)
These cells also displayed aberrant stem cell markers, notably Nanog, SOX-2, SOX-17 and E-cadherin. (cdc.gov)
Restored expression of tumor suppressor p53 abrogated CSC properties of CSC-like cells. (cdc.gov)
Depending on the origin of the tumor (e.g., ovaries), the CSC surface biomarker profile can vary dramatically, making the identification of such cells via immunohistochemical staining a challenging endeavor. (bvsalud.org)
On the contrary, aldehyde dehydrogenase 1A1 (ALDH1A1) has emerged as an excellent marker to identify CSCs, owing to its conserved expression profile in nearly all progenitor cells including CSCs. (bvsalud.org)
Cancer stem cells are a population of slow-cycling cells within the tumour bulk, with self-renewal capacity that attracts interest as a therapeutic target. (lu.se)
In highly heterogeneous tumours, like pancreatic ductal adenocarcinoma (PDAC) however, the characterisation of cancer stem cells has led to controversial results due to the lack of consensus on specific markers. (lu.se)

Irregular tumor borders can be suggestive of tumor invasiveness and associated histologic malignancy. (medscape.com)

No additional clinical data will be collected in the iDx lung biomarker sub-study but biological samples will instead be linked to data collected as part of the main study. (southampton.ac.uk)
Ideally, a clinician could identify a tumour biomarker from a simple blood test. (ddw-online.com)

The acquired knowledge could facilitate and accelerate the development of new diagnostic and prognostic markers, new targets for pharmaceutical interventions, and new cancer prevention and treatment strategies. (nih.gov)
The major advantage of using immune markers by flow cytometry is the identification of particular leukemia subtype, not recognized by morphologic criteria, which may have prognostic significance. (medscimonit.com)
As peritoneal implants are a significant prognostic index and the most common sites of implants include the omentum and peritoneal surfaces, surgical staging that includes resection of the primary borderline tumour, abdominal/pelvic cytologic washings, omentectomy, and peritoneal biopsies is recommended. (researchsquare.com)
We compared the power of gene expression measurements with that of conventional prognostic markers, i.e., clinical, histo- pathological, and cell biological parameters, for predicting distant metastases in breast cancer patients using both established prognostic indices (e.g., the Nottingham Prognostic Index (NPI)) and novel combinations of conventional markers. (lu.se)
Our analysis suggests that it might be possible to improve the combination of different conventional prognostic markers into one prognostic index. (lu.se)
Although these comparisons favoured the gene expression markers, this was usually in comparison against single factors and the new tech- q Sources of support: Swedish Research Council, Swedish Founda- nology has not been tested against a combined index, tion for Strategic Research, Lund University Medical Faculty and the such as the Nottingham Prognostic Index (NPI). (lu.se)
Although recent studies suggest a less favorable prognosis for patients with germinomas secreting bhCG, no established prognostic significance of tumor markers exists. (medscape.com)

Furthermore, the clear heterogeneity of CRC tumors indicates a clear need for new biological markers and therapeutic targets for CRC. (hindawi.com)
They express markers of less differentiated cone together with neuronal/ganglion cell markers with marked inter- and intra-tumor heterogeneity. (nih.gov)

The objective of this study was to evaluate clinical and microscopic features of squamous cell carcinomas using immunohistochemical analysis and assessing biological markers of angiogenesis and tumor vascular activity (anti-CD31, anti-CD34, Factor VIII), cell proliferation (Ki-67), and loss of cell suppression (p53). (bvsalud.org)

Proteomics have emerged as a valid methodology to analyze biological systems at molecular level. (mdpi.com)
Little is known on the molecular basis underlying the biological and clinical behavior of this cancer. (nih.gov)
NEW YORK - Researchers have identified new strategies for predicting response to immunotherapy, using approaches that integrate genomic and molecular signals, immune cell phenotypes, and other biological markers related to the body's anti-tumor immune response. (genomeweb.com)

PLAP is a tumor marker, especially in seminoma and ovarian cancer (e.g., dysgerminoma). (wikipedia.org)
They lower levels of several growth factors that promote breast cancer and increase the expression of tumor suppressor genes. (aicr.org)
Cruciferous vegetables, which contain phytochemicals, inhibit a wide range of cancer-promoting cellular processes, including angiogenesis (new blood vessel growth), which is needed for tumor growth and fat tissue growth. (drfuhrman.com)
Although the primary importance of CTCs is their ability to seed metastatic tumors, their constant presence in the blood have made their detection an attractive alternative to the traditional biopsy for clinical applications such as cancer screening, therapy evaluation and disease prognosis. (uh.edu)
Colorectal cancer (CRC) is the third most common form of malignant tumor and is characterized by high rates of proliferation and metastases. (hindawi.com)
The overall goal of all CCG programs is to help elucidate the mechanisms of cancer initiation and evolution, as well as resistance to therapy by means of genomic characterization of well-annotated, high quality tumor samples. (nih.gov)
One of these strategies was discussed by Kevin Litchfield at the University College London Cancer Institute, whose team conducted a meta-analysis using publicly available exome and transcriptome data from more than 1,000 patients with various tumor types enrolled in multiple immunotherapy studies. (genomeweb.com)
Investigators reanalyzed this data using a standardized bioinformatics pipeline to identify various signatures that captured cancer cell states, tumor immune inflammation, and immune inhibitory pathways. (genomeweb.com)
They reported that this score outperformed TMB across a number of tumor-specific datasets, including pan-cancer samples, lung cancer, and melanoma. (genomeweb.com)
Many new anti-cancer therapies are evaluated based on their ability to shrink tumors. (atlasantibodies.com)
The relationship between risk scores and tumor mutation burden (TMB), cancer stem cell index, and drug sensitivity was explored. (biomedcentral.com)
Although there are more than 60 commonly-used cancer markers available (1), new discoveries are slow to progress through validation and reach clinical use, and the challenge continues to find those with sufficient sensitivity (to detect disease correctly) and specificity (to reject healthy individuals correctly). (ddw-online.com)
Breast cancer patients can be cured either by local markers are therefore called for. (lu.se)
European Journal of Cancer 40 (2004) 1837-1841 since approximately half of all new breast cancers are the St. Gallen criterion [1], which are based upon dif- diagnosed in the third world, where the analyses of ferent subsets of these conventional markers. (lu.se)
This prospective study in Yazd, Islamic Republic of Iran, assessed the value of the tumour markers carcinoembryonic antigen (CEA) and cancer antigen (CA) 15-3 in 159 patients with primary breast cancer. (who.int)
Here we investigated the characteristics of a population of pancreatic cancer tumorspheres derived from different human pancreatic cancer cell lines and a primary line from a genetically engineered KPC mouse model, using flow cytometry and western blotting to analyse surface and stemness markers. (lu.se)
Pancreatic cancer tumorspheres display a heterogeneous pattern of surface and stemness markers, nevertheless they are characterised by an increased tumorigenic potential and higher chemoresistance. (lu.se)

Following the preparation process, expression of markers was detected by using flow cytometry. (medscimonit.com)
Expression levels of PB and BM markers were compared by using statistical analysis.Results:The results showed apparent discrepancies for some markers in ALL group. (medscimonit.com)
The recognition of these two subtypes, one maintaining a cone-differentiated state, and the other, more aggressive, associated with cone dedifferentiation and expression of neuronal markers, opens up important biological and clinical perspectives for retinoblastomas. (nih.gov)
According to the authors, two parameters - clonal TMB and the gene CXCL9 - were the strongest predictors across the dataset, beating out other putatively predictive factors including various established gene-expression-based scores of tumor immune response and immune cell infiltration. (genomeweb.com)
Our results suggest that smoking may induce increased HER2 expression in recurrent breast tumors. (biomedcentral.com)
Therefore, it is necessary to re-evaluate the receptor expression status when a recurrent tumor arises. (biomedcentral.com)
In recent exploratory regional therapy alone or by the addition of systemical studies, markers from microarray gene expression medical therapy with increased side effects and costs. (lu.se)
This was expression markers identified in the study by van 't Veer done by sequentially leaving one patient out for a blind and colleagues [2] compare with conventional markers. (lu.se)
Significant variability in expression of tumor markers is such that the absence of AFP or bhCG does not rule out a mixed germ cell tumor. (medscape.com)

The perception of laboratory personnel has been that the biological variation model would be impractical in the setting of the quality specifications for clinical laboratories so this has limited the implementation of these types of quality specifications. (westgard.com)
The clinical management of BOT has evolved over the last two decades since our understanding of its biological behaviour has increased. (researchsquare.com)
as a result, the clinical and histological characteristics and prognosis of this tumor have not been extensively investigated. (bvsalud.org)

By contrast, subtype 2 tumors harbor frequent recurrent genetic alterations including MYCN-amplification. (nih.gov)
When ER was evaluated in recurrent tumors, negative and positive conversions were recognized in 3 (6.0%) and 1 patient (2.0%), respectively. (biomedcentral.com)

therefore, definitive differentiation of Hürthle cell carcinoma from Hürthle-cell adenoma is based on vascular invasion and/or capsular invasion, as well as on permanent histologic sections or extrathyroidal tumor spread and lymph node and systemic metastases. (medscape.com)

CTCs usually lose the protein markers after EMT, hence won't be detectable by the current method. (uh.edu)

For lung cancers, CSC markers include CD44 and CD133 (PROM1), but also CD117 (KIT), CD90 (or THY1), CD166, EpCAM for non-small-cell lung carcinoma (NSCLC), and PODXL-1, PTCH, and CD87 for small-cell lung carcinoma (SCLC) 25 . (atlasantibodies.com)
[ 5 ] The 2022 WHO classification of endocrine tumors has replaced the term Hürthle cell carcinoma with oncocytic carcinoma. (medscape.com)

Also notable in this research was the fact that certain markers that have previously been reported to have strong predictive power completely failed to replicate in this meta-analysis, including the burden of somatic copy number alterations. (genomeweb.com)
Rising levels of markers of tumour burden (CK18) and potential resistance (VEGFR2) are associated with worse outcomes and warrant validation. (nature.com)

Tumor Markers in Testicular Cancers" (PDF). (wikipedia.org)
In primary tumors, such as colon and breast cancers, overexpression of RON exists in a large number of cases and is often accompanied by the generation of different splicing variants ( 12 - 14 ). (spandidos-publications.com)
Here we provide an overview of the most prominent CSC markers, focusing on solid cancers (lung, stomach, liver, breast, and colorectal cancers) and hematological cancers (acute and chronic myeloid leukemia). (atlasantibodies.com)

The terms 'neoplasm' and 'tumour' are used interchangeably. (who.int)

The spread of tumor in the peritoneal cavity is an adverse factor and therapeutic challenge for a variety of malignancies. (snmjournals.org)

The surgical approach may be an incisional biopsy, which removes only part of the abnormal area, or an excisional biopsy, which removes the entire tumor. (medpagetoday.com)
A margin or edge of normal breast tissue around the tumor may also be removed, depending on the reason for the biopsy. (medpagetoday.com)
Before any other treatment began, my doctor's plan was to perform a cervical lymph node biopsy testing for a tumor marker that would secure eligibility for a biological treatment. (lung.org)

We compared our system performance characteristics in term of imprecision and bias against allowable imprecision and bias derived from the biological variation. (westgard.com)
Chemical analogues and compounds with biological or physical characteristics similar to those of suspected carcinogens may also be considered, even in the absence of data on a possible carcinogenic effect in humans or experimental animals. (who.int)

We encourage you to submit up-to-date review and research articles concerning these topics in different biological systems, in vitro and in vivo . (mdpi.com)

However, in AML patients most of the selected markers have shown considerable correlation between PB and BM samples. (medscimonit.com)
Samples of adrenal tumors were collected from patients undergoing adrenalectomy at the Department of Urology, the First Hospital of China Medical University. (cancerindex.org)

This may contribute to the generation of active RON variants by alternative splicing, which is frequently observed in primary tumors. (spandidos-publications.com)

related chemical compounds, physical agents (such as radiation) and biological factors (such as viruses). (who.int)

The research must include quality human studies that meet specific criteria and biological explanations for the findings. (aicr.org)

Using CD133 (PROM1) as a positive marker for colon CSCs also generated conflicting results 24 . (atlasantibodies.com)

This discipline now permits not only an optimal generation of experimental data but also increased capabilities in data analysis for a successful biological interpretation. (mdpi.com)

2016. Modeling of genetic gain for single traits from marker-assisted seedling selection in clonally propagated crops. (wsu.edu)
It harbors few genetic alterations other than the initiating RB1 inactivation and corresponds to differentiated tumors expressing mature cone markers. (nih.gov)

Borderline ovarian tumour (BOT) is a peculiar type of tumour with a more favourable prognosis than malignant ovarian tumours. (researchsquare.com)

In recent years, glycans have been increasingly recognised as mediators of important biological processes, and studies are improving our understanding of a range of human diseases, and how to treat them (4). (ddw-online.com)
As with radiologic studies, these results can be suggestive of tumor type but only occasionally provide the physician diagnostic information. (medscape.com)

However, a comprehensive investigation of whether RON is involved in the formation of various types of tumors has not been adequately carried out. (spandidos-publications.com)

One crucial ability of the CSCs is to form tumors already at low cell numbers. (atlasantibodies.com)
However, if these therapies are not destroying CSCs, the tumor will soon grow back, often with high resistance to treatments 2 . (atlasantibodies.com)

Anatomy9

Organisms6

Diseases91

Chemicals and Drugs63

Analytical, Diagnostic and Therapeutic Techniques and Equipment54

Phenomena and Processes36

Disciplines and Occupations2

Information Science5

Health Care15

Biomarkers3

Malignant tumors3

Solid Tumors1

Germ cell t6

Prognosis and fertili1

Progression4

Brain Tumors1

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Serum5

Circulating tumor cells5

Recurrence2

NEOPLASMS1

Diagnosis5

Metastasis4

Antigens1

Subpopulation3

Cells22

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Prognostic7

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Molecular3

Cancer17

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Histologic1

CTCs1

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Burden2

Cancers3

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