• suppressor genes
  • Both such subtypes are associated with mutations in the short-arm of chromosome 3, with the implicated genes being either tumour suppressor genes (VHL and TSC) or oncogenes (like c-Met). (wikipedia.org)
  • A variable percentage of cells within the LAM lesion contain mutational inactivation of the Tuberous Sclerosis Complex (TSC1 or TSC2) tumor suppressor genes. (wikipedia.org)
  • malignant
  • Wilms tumour (WT), also called nephroblastoma, is an embryonal malignant neoplasm of the kidney accounting for 6-7% of all childhood cancers [ 1 - 3 ]. (pubmedcentralcanada.ca)
  • The released tumor antigens help activate anti-tumor T cells, which destroy remaining malignant cells. (wikipedia.org)
  • The enzyme suggested as a tumor marker in malignant disease is the cytosolic cell cycle dependent TK1 that is present during cell division in quantities much larger than TK2 and is therefore set free to the circulation in quantities that completely dominate the activity of thymidine kinase in blood and other body fluids. (wikipedia.org)
  • The thymidine kinase level in serum therefore serves as a measure of malignant proliferation, indirectly as a measure of the aggressivity of the tumor. (wikipedia.org)
  • However, they may be resected to exclude a malignant tumor, e.g. renal cell carcinoma. (wikipedia.org)
  • robotic
  • In this Intuitive Surgical video, noted Belgian robotic surgeon and Vattikuti Foundation partner, Dr. Alexandre Mottrie has a 33-year-old woman with a large tumor on the right kidney. (vattikutifoundation.com)
  • Transoral resection of tumors of the upper aerodigestive tract (tonsil, tongue base, larynx) and transaxillary thyroidectomy Resection of spindle cell tumors originating in the lung Although the general term "robotic surgery" is often used to refer to the technology, this term can give the impression that the da Vinci System is performing the surgery autonomously. (wikipedia.org)
  • chemotherapy
  • Although in most cases of WT such therapy induces a considerable degree of tumour shrinkage and the overall survival is greater than 90%, a proportion of cases show a limited volume reduction and retain an abundance of blastemal tissue post-chemotherapy. (pubmedcentralcanada.ca)
  • cancers
  • Cryoimmunotherapy, also referred to as cryoimmunology, is an oncological treatment for various cancers that combines cryoablation of tumor with immunotherapy treatment. (wikipedia.org)
  • the associated kidney cancers are often rare hybrid tumors. (wikipedia.org)
  • spontaneous
  • Renal cell carcinoma (RCC) is a tumor with clinically apparent immunologic phenomena, such as response to immunotherapies (interferon, interleukin-2, immune cellular therapy etc), spontaneous regression, and sometimes indolent behaviour. (clinicaltrials.gov)
  • some families with the mutation that causes BHD develop only kidney tumors or spontaneous pneumothorax. (wikipedia.org)
  • warm ischemia time
  • Statistically significant correlation was appreciated between tumor location (polar location, side, anterior/ posterior location) and RENAL score and operative parameters (warm ischemia time and operation duration). (heighpubs.org)
  • Although the renal hilum vasculature was isolated for possible clamping if needed, tumor extirpation was performed off-clamp, eliminating warm ischemia time (WIT). (hofstra.edu)
  • endophytic
  • RENAL nephrometry score was assessed from points assigned for Tumor radius, Exophytic/endophytic properties, Nearness to the collecting system, Anterior/posterior location and Location relative to polar lines. (heighpubs.org)
  • familial
  • Other genetically linked conditions also increase the risk of RCC, including hereditary papillary renal carcinoma, hereditary leiomyomatosis, Birt-Hogg-Dube syndrome, hyperparathyroidism-jaw tumor syndrome, familial papillary thyroid carcinoma, von Hippel-Lindau disease and sickle cell disease. (wikipedia.org)
  • There are some familial cases in which these tumors are multicentric rather than solitary. (wikipedia.org)
  • blood vessels
  • Therapeutic interventional oncology procedures may be classified further into ablation techniques that destroy neoplastic tissues by delivery of some form of heat, cryo or electromagnetic energy and embolization techniques that aim to occlude the blood vessels feeding the tumour and thereby destroy it by means of ischemia. (wikipedia.org)
  • organs
  • People over 20 years of age with Birt-Hogg-Dubé syndrome have an increased risk of developing slow-growing kidney tumors (chromophobe renal carcinoma and renal oncocytoma, respectively), kidney cysts, and possibly tumors in other organs and tissues. (wikipedia.org)
  • 1997
  • 1997 - Intra-arterial delivery of tumor-killing viruses and gene therapy vectors to the liver. (wikipedia.org)
  • Oncology
  • Interventional oncology procedures are generally divided between diagnostic procedures that help obtain tissue diagnosis of suspicious neoplasms and therapeutic ones that aim to cure or palliate the tumour. (wikipedia.org)
  • complications
  • However, due to limited x-ray and imaging capabilities to find small kidney tumors and significant complications associated with early operations it was largely abandoned. (wikipedia.org)
  • syndrome
  • Birt-Hogg-Dubé syndrome (BHD), also Hornstein-Birt-Hogg-Dubé syndrome, Hornstein-Knickenberg syndrome, and fibrofolliculomas with trichodiscomas and acrochordons is a human autosomal dominant genetic disorder that can cause susceptibility to kidney cancer, renal and pulmonary cysts, and noncancerous tumors of the hair follicles, called fibrofolliculomas. (wikipedia.org)
  • Along with the tumors, other skin conditions are seen in people with Birt-Hogg-Dubé syndrome. (wikipedia.org)
  • Tumor Lysis Syndrome 11. (wikipedia.org)
  • decline
  • Aim of this prospective, observational study was to find histo-pathological factors in the non-tumor renal parenchyma that could predict the decline in global renal function postoperatively and its association with co-morbidities like diabetes (DM). (intbrazjurol.com.br)
  • complex
  • TSC1 and TSC2 form a tumor suppressor complex that regulates mammalian target of rapamycin (mTOR) signaling complex by directly controlling the activity of the small GTPase Rheb via the GTPase activating protein (GAP) domain of TSC2. (wikipedia.org)
  • typically
  • Ameloblastoma is an aggressive odontogenic tumor which typically occurs between third and fourth decade of life that often needs resective approach. (readbyqxmd.com)
  • large
  • A large number of tumors on the face can be associated with hyperseborrhea (abnormally elevated sebum production). (wikipedia.org)