• suppressor genes
  • Both such subtypes are associated with mutations in the short-arm of chromosome 3, with the implicated genes being either tumour suppressor genes (VHL and TSC) or oncogenes (like c-Met). (wikipedia.org)
  • A variable percentage of cells within the LAM lesion contain mutational inactivation of the Tuberous Sclerosis Complex (TSC1 or TSC2) tumor suppressor genes. (wikipedia.org)
  • endophytic
  • RENAL nephrometry score was assessed from points assigned for Tumor radius, Exophytic/endophytic properties, Nearness to the collecting system, Anterior/posterior location and Location relative to polar lines. (heighpubs.org)
  • donor
  • This short course focuses on practical issues that are frequently encountered by the practicing general surgical pathologist when evaluating tumor nephrectomy/nephroureterectomy specimens, autopsies, and donor kidneys. (uscap.org)
  • The course is designed for surgical pathologists and pathologists in training, who are responsible for nephrectomy and autopsy cases, or are involved with frozen section evaluation of donor kidneys. (uscap.org)
  • Nephrectomy is also performed for the purpose of living donor kidney transplantation. (wikipedia.org)
  • nephroureterectomy
  • in 1875 being credited with achieving the first recorded occurrence of cure by nephrectomy in France, and in 1898, with Joaquín Albarrán (1860-1912), performing the first nephroureterectomy for upper tract urothelial cancer. (wikipedia.org)
  • surgery
  • An analysis of Surveillance, Epidemiology and End Results (SEER) registry data that Dr. Miller and colleagues reported today in the March issue of the Journal of Urology found that all-cause mortality was similar for partial nephrectomy and total nephrectomy, yet only 42% of patients with masses smaller than 2 cm received this kidney-sparing surgery. (medpagetoday.com)
  • tumors ≤ 4 cm were at least 3.8 times more likely to be treated with nephron sparing surgery. (medpagetoday.com)
  • Additionally, partial nephrectomy has a higher risk of bleeding or urine leak after surgery, which may argue against using that approach. (medpagetoday.com)
  • Similar to surgery for early breast cancer, clarification of the optimal use of PN may well require a more sophisticated understanding of patient preferences for partial versus total nephrectomy. (medpagetoday.com)
  • There was no complication during the perioperative period, and the pathology diagnosis after the surgery showed that there were 13 renal clear cell carcinomas, two papillary carcinoma and four perivascular epithelioid cell tumors with negative margins from the 19 tumors. (biomedcentral.com)
  • Of 29 patients, 16 (55.2%) had successful LRN (Group A), while 13 (44.8%) had conversion to open surgery (group B). The median tumor size in Group A was 11.3 ± 1.8 cm and in Group B was 13.6 ± 1.26 cm. (urologiajournal.com)
  • Such alternatives include renal embolization for those who are poor candidates for surgery, or partial nephrectomy if possible. (wikipedia.org)
  • Transoral resection of tumors of the upper aerodigestive tract (tonsil, tongue base, larynx) and transaxillary thyroidectomy Resection of spindle cell tumors originating in the lung Although the general term "robotic surgery" is often used to refer to the technology, this term can give the impression that the da Vinci System is performing the surgery autonomously. (wikipedia.org)
  • Causes include prolonged supine bed rest, scoliosis surgery, left nephrectomy, ileo-anal pouch surgery. (wikipedia.org)
  • malignant
  • The released tumor antigens help activate anti-tumor T cells, which destroy remaining malignant cells. (wikipedia.org)
  • The enzyme suggested as a tumor marker in malignant disease is the cytosolic cell cycle dependent TK1 that is present during cell division in quantities much larger than TK2 and is therefore set free to the circulation in quantities that completely dominate the activity of thymidine kinase in blood and other body fluids. (wikipedia.org)
  • The thymidine kinase level in serum therefore serves as a measure of malignant proliferation, indirectly as a measure of the aggressivity of the tumor. (wikipedia.org)
  • However, they may be resected to exclude a malignant tumor, e.g. renal cell carcinoma. (wikipedia.org)
  • Specimens
  • Given that the majority of kidney cancers are T1 tumors, which have a 5-year survival rate that approaches 100%, non-neoplastic kidney diseases are emerging as the most important diagnoses to establish during the evaluation of tumor nephrectomy specimens. (uscap.org)
  • cancers
  • Cryoimmunotherapy, also referred to as cryoimmunology, is an oncological treatment for various cancers that combines cryoablation of tumor with immunotherapy treatment. (wikipedia.org)
  • the associated kidney cancers are often rare hybrid tumors. (wikipedia.org)
  • spontaneous
  • Renal cell carcinoma (RCC) is a tumor with clinically apparent immunologic phenomena, such as response to immunotherapies (interferon, interleukin-2, immune cellular therapy etc), spontaneous regression, and sometimes indolent behaviour. (clinicaltrials.gov)
  • some families with the mutation that causes BHD develop only kidney tumors or spontaneous pneumothorax. (wikipedia.org)
  • papillary
  • Other genetically linked conditions also increase the risk of RCC, including hereditary papillary renal carcinoma, hereditary leiomyomatosis, Birt-Hogg-Dube syndrome, hyperparathyroidism-jaw tumor syndrome, familial papillary thyroid carcinoma, von Hippel-Lindau disease and sickle cell disease. (wikipedia.org)
  • Exophytic
  • Tumors were exophytic with the R.E.N.A.L score ranged from 4 to 6 points (mean of 4.4 points) and the diameter of them ranged from 1.8 to 3.5 cm (mean of 2.5 cm). (biomedcentral.com)
  • resection
  • The line of resection was point mapped using hook electrocautery keeping a generous margin from the tumor edge. (heighpubs.org)
  • favorable
  • The objective of the study is to determine whether a specific immune microenvironment in the primary tumor is associated with a favorable clinical course after nephrectomy and in the absence of adjuvant treatment. (clinicaltrials.gov)
  • blood vessels
  • Therapeutic interventional oncology procedures may be classified further into ablation techniques that destroy neoplastic tissues by delivery of some form of heat, cryo or electromagnetic energy and embolization techniques that aim to occlude the blood vessels feeding the tumour and thereby destroy it by means of ischemia. (wikipedia.org)
  • occur
  • Less frequently AKI can occur due to obstruction to urine flow from tumor or lymph node enlargement. (wikipedia.org)
  • 1997
  • 1997 - Intra-arterial delivery of tumor-killing viruses and gene therapy vectors to the liver. (wikipedia.org)
  • Oncology
  • Interventional oncology procedures are generally divided between diagnostic procedures that help obtain tissue diagnosis of suspicious neoplasms and therapeutic ones that aim to cure or palliate the tumour. (wikipedia.org)
  • suffix
  • The -oma suffix indicates a tumour. (wikipedia.org)
  • Onconephrology (from the Ancient Greek onkos (ὄγκος) meaning bulk, mass, or tumor, nephros (νεφρός) meaning kidney, and the suffix -logy (-λογία), meaning "study of") is a burgeoning new specialty in nephrology that deals with the study of kidney diseases in cancer patients. (wikipedia.org)
  • complications
  • The overall complication rate for all tumors was 22.2% (249/1,123), including 183 (16.3%) minor and 66 (5.9%) major complications. (auanet.org)
  • For hilar tumors, the complication rate was 30.9% (30/97), including 21 (21.6%) minor and 9 (9.3%) major complications. (auanet.org)
  • However, due to limited x-ray and imaging capabilities to find small kidney tumors and significant complications associated with early operations it was largely abandoned. (wikipedia.org)
  • syndrome
  • Birt-Hogg-Dubé syndrome (BHD), also Hornstein-Birt-Hogg-Dubé syndrome, Hornstein-Knickenberg syndrome, and fibrofolliculomas with trichodiscomas and acrochordons is a human autosomal dominant genetic disorder that can cause susceptibility to kidney cancer, renal and pulmonary cysts, and noncancerous tumors of the hair follicles, called fibrofolliculomas. (wikipedia.org)
  • Along with the tumors, other skin conditions are seen in people with Birt-Hogg-Dubé syndrome. (wikipedia.org)
  • Tumor Lysis Syndrome 11. (wikipedia.org)