• cardiac
  • OBJECTIVE To compare cardiac troponin T release and lactate metabolism in coronary sinus and arterial blood during uncomplicated coronary grafting on the beating heart with conventional coronary grafting using cardiopulmonary bypass. (bmj.com)
  • DESIGN A prospective observational study with simultaneous sampling of coronary sinus and arterial blood: before and 1, 4, 10, and 20 minutes after reperfusion for analysis of cardiac troponin T and lactate. (bmj.com)
  • Cardiac troponin T was also analysed in venous samples taken 3, 6, 24, 48, and 72 hours after surgery. (bmj.com)
  • RESULTS Cardiac troponin T was detected in coronary sinus blood in all patients by 20 minutes after beating heart coronary artery surgery before arterial concentrations were consistently increased. (bmj.com)
  • CONCLUSIONS Lower intraoperative and serial venous cardiac troponin T concentrations suggest a lesser degree of myocyte injury during beating heart coronary artery surgery than during cardiopulmonary bypass. (bmj.com)
  • Coronary sinus cardiac troponin T concentrations increased earlier and were greater than arterial concentrations during beating heart surgery, suggesting that this may be a more sensitive method of intraoperative assessment of myocardial injury. (bmj.com)
  • 1 We have therefore correlated the early myocardial release and later venous concentrations of cardiac troponin T, 2 3 a highly specific and sensitive marker of myocardial cell injury, with the recovery of oxidative metabolism in patients undergoing coronary artery bypass grafting on the beating heart. (bmj.com)
  • Histological evidence for reversible cardiomyocyte changes and serum cardiac troponin T elevation after exercise in rats. (ljmu.ac.uk)
  • This study characterized cardiac troponin T (cTnT) appearance and associated histological evidence of reversible or irreversible changes in myocardial ultrastructure, determined via electron microscopy, in rats undertaking isoproterenol (ISO) infusion or an endurance exercise challenge. (ljmu.ac.uk)
  • Cardiac troponin T (cTnT) is established as a specific biomarker of ongoing myocardial damage and predicts adverse outcome in patients with heart failure (HF). (ahajournals.org)
  • We sampled from aortic root (Ao) and coronary sinus (CS) simultaneously during cardiac catheterization, and measured serum cTnT levels using Elecsys-2010 Troponin T hs STAT kit (Roche Diagnostics) and plasma B-type natriuretic peptide (BNP) levels using MI02 Shionogi BNP kit (Shionogi). (ahajournals.org)