Phytochemical investigations of the roots of Spergularia marginata had led to the isolation of four previously undescribed triterpenoid saponins, a known one and one spinasterol glycoside. (unboundmedicine.com)
Some of the active constituents in gotu kola include triterpene saponins such as asiaticoside, madecassoside and madasiatic acid. (superfoodevolution.com)
Among many secondary metabolites it produces, the effective bioactive constituents include isoflavonoids and triterpene saponins. (biomedcentral.com)
Unigenes associated with secondary metabolism, especially those with isolavonoids and triterpene saponins biosynthesis were characterized and profiled. (biomedcentral.com)
Further co-expression analysis indicated the candidate CYP450s and glycosyltransferases (GTs) in the cascade of triterpene saponins biosynthesis. (biomedcentral.com)
Ginsenosides, triterpenoid saponins with a four-ring skeleton structure, are unique to ginseng genus. (biomedcentral.com)
To date, more than 200 triterpene saponins have been isolated and characterized from the root, stem, leaf, flower and fruit of P. ginseng [ 9 ]. (biomedcentral.com)
Rasa pahit peria katak ini disebabkan oleh kahadiran triterpenoid saponins jenis cucurbitacin contohnya sebatian kimia momordicosides K dan L. (drcheputeh.com)
The soapbark tree ( Quillaja saponaria , Molina) contains high concentrations of triterpenoid saponins which consist of a triterpene aglycone linked to saccharide side chains. (orffa.com)
Triterpenoid saponins are well known for their antiprotozoal effects. (orffa.com)
Based on the chemical profile analysis, 32 compounds were successfully or tentatively identified, including gallic and ellagic acid derivatives, flavonol glycosides, triterpenes and pheophorbides. (biomedcentral.com)
Ia mengandungi sejenis protein bernama polypeptida-d dan sekumpulan sebatian kimia cucubitacins, sejenis triterpenoid glycosides yang berpotensi merawat diabetes di dalam kajian ke atas tikus. (drcheputeh.com)
Ini kerana ia mempunyai satu bahagian yang tidak larut air iaitu bahagian triterpene, dan bahagian yang larut air iaitu glycosides. (drcheputeh.com)
Polysaccharides2
This leading brand of Reishi combines hot-water (polysaccharide rich) and ethanolic extracts of log-grown (Duan Wood) Ganoderma lucidum to deliver high levels of both polysaccharides and triterpenes. (healthy.co.uk)
In addition, important active principles, such as triterpenes, triterpenoids, polysaccharides and adenosine take part in this complete matrix. (clinicaltrialsarena.com)
Compounds6
Antiallergic activity has been demonstrated by G. lucidum extracts, as well as some compounds isolated from this species, such as ganoderic acids, oleic acid, and cyclooctasulfur acid belonging to triterpenes [80]. (researchgate.net)
It includes a new friedelan triterpene (1), together with the known compounds friedelin, 3-oxo-29-hydroxyfriedelane, 3- oxofriedelan-25-al, and canophyllol. (edu.pe)
We have previously attributed the hypoglycaemic effects of Syzygium cordatum leaf extract to crude ethyl acetate extract solubles (EAS) containing triterpenoid compounds. (endocrine-abstracts.org)
Alisol derivatives are unique protostane-type triterpenoid compounds that are isolated from Alismatis rhizoma, which is a well-known traditional medicine in East Asia. (ewha.ac.kr)
Organic Reishi mushroom supplement by MycoNutri contains over 100 triterpenoid compounds including gonoderic and lucidenic acids. (healthy.co.uk)
Additionally, Reishi mushrooms are chock full of triterpenoids (compounds that actually make plants bitter to deter animals from eating them). (moonjuice.com)
Acids4
The plant kingdom, including medicinal and dietary plants, offers many natural phytochemicals that include phenolic diterpenes, triterpenes, flavonoids, phenolic acids and sterols [ 21 - 23 ]. (ijpsonline.com)
Komissarova Nataliya G., Belenkova Nataliya G., Shitikova Olga V., Spirikhin Leonid V., Yunusov Marat S.: Oxidative Decarboxylation of Triterpene C-28 Acids of Lupane Series. (cas.cz)
triterpenes and triterpenoids (ganoderic acids, etc. (mykosan.com)
Also known as ganoderic acids, triterpenes are used for medicinal purposes in many Asian countries. (evidencelive.org)
Sterols2
Squalene serves as precursor for the formation of many triterpenoids, including bacterial hopanoids and eukaryotic sterols. (wikipedia.org)
Triterpenoids possess a rich chemistry and pharmacology (e.g. cholesterol) with several pentacyclic motifs. (wikipedia.org)
Kvasnica Miroslav, Urban Milan, Dickinson Niall J., Sarek Jan: Pentacyclic triterpenoids with nitrogen- and sulfur-containing heterocycles: synthesis and medicinal significance. (cas.cz)
Pentacyclic triterpenes with isopropyl and its derivatives at the C19 position. (bvsalud.org)
Tripterygium wilfordii has been renowned mostly because of the anticancer effects of its root extracts, which is partly ascribed to the presence of celastrol, a pentacyclic triterpenoid, as one of the main active components. (techscience.com)
Among the T. wilfordii terpenoids, triptolide (a diterpenoid epoxide) and celastrol (a pentacyclic triterpenoid) have received the most interest due to their anticancer and anti-inflammatory activities [ 5 , 6 ]. (techscience.com)
For triterpene saponin biosynthesis, we found the genes in MVA and non-MVA pathways were differentially expressed among three examined tissues, indicating the parallel but compartmentally separated biosynthesis pathways of IPP and DMAPP in A. mongolicus . (biomedcentral.com)
The first committed enzyme in triterpene saponin biosynthesis from A. mongolicus , cycloartenol synthase (AmCAS), which belongs to the oxidosqualene cyclase family, was cloned by us to study the astragalosides biosynthesis. (biomedcentral.com)
Glycyrrhizic acid (also known as glycyrrhizinic acid) is a naturally occurring triterpenoid saponin found in the extracts of roots and rhizomes from Glycyrrhiza glabra, the licorice plant. (affygility.com)
Maytenus3
A set of friedelane triterpenoids has been isolated from the stem bark exudates of Maytenus macrocarpa. (edu.pe)
Macrocarpins A-D, new cytotoxic nor-triterpenes from Maytenus macrocarpa. (rxlist.com)
According to a report published by the Amala Cancer Research Centre of India in the "Mutation Research" in January 2017, Ganoderma lucidum triterpenes, which can effectively inhibit the survival of cancer cells, can reduce the occurrence and severity of tumors, whether used externally or internally. (ganoherb.com)
Ganoderma11
The triterpenoid fraction (100 and 200 mg/kg) of the fruit bodies of Ganoderma lucidum inhibited primary solid-tumor growth in the spleen, liver metastasis and secondary metastatic tumor growth in the liver in intrasplenic Lewis lung carcinoma (LLC)-implanted mice. (nih.gov)
The study used the total triterpenoid extract of the fruiting body of Ganoderma lucidum. (ganoherb.com)
Further analysis of the anti-cancer mechanism of Ganoderma lucidum total triterpenes revealed that after cancer cells are adjusted by Ganoderma lucidum triterpenes, many genes and protein molecules in the cells will undergo great changes. (ganoherb.com)
After 1 week, the researchers applied croton oil, a substance that promotes tumor growth, to the same area twice a week, and also applied 5, 10, or 20 mg of Ganoderma lucidum triterpenes 40 minutes before each application of croton oil for 8 consecutive weeks (the 2nd to 9th week of the experiment). (ganoherb.com)
At the end of the 18th week of the experiment, the mice in the untreated control group, regardless of the incidence of tumors, the number of tumors that grew, and the time to grow the first tumor, were significantly different from the mice that were applied with 5, 10, and 20 mg of Ganoderma lucidum triterpenes (as shown in the figure below). (ganoherb.com)
The second is the "breast cancer" experiment: mice were fed carcinogen DMBA once a week for 3 weeks, and from the next day after the first carcinogen feeding (24 hours later), 10, 50 or 100 mg/kg of Ganoderma lucidum triterpenes were fed every day for 5 consecutive weeks. (ganoherb.com)
The tumor weights of mice protected with 10, 50 or 100 mg/kg total extract of Ganoderma lucidum triterpenes were only two-thirds, one-half and one-third of the tumor weights of mice in the control group, respectively. (ganoherb.com)
Glycyrrhetinic1
It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. (affygility.com)
Medicinal1
3 key elements in medicinal mushrooms like Reishi include beta-glucans, triterpenoids, and ergosterol. (moonjuice.com)
Extract1
In addition, the triterpenoid fraction (800 micrograms/mL) inhibited angiogenesis induced by Matrigel (a soluble basement membrane extract of the Engelbreth-Holm-Swam (EHS) tumor) supplemented with vascular endothelial growth factor (VEGF) and heparin in an in vivo model. (nih.gov)
This suggested that the antitumor and antimetastatic activities of the triterpenoid fraction of G. lucidum might be due to the inhibition of tumor-induced angiogenesis. (nih.gov)
Fraction2
The acidic fraction of the triterpenoid fraction inhibited the Matrigel-induced angiogenesis. (nih.gov)
The triterpene fraction dose-dependently acts by different and complementary mechanisms to improve the mucosal defensive factors. (propolisscience.org)
Ergosterol is a type of triterpenoid present in all fungi. (moonjuice.com)
Skeleton1
Achilleol A: A new monocyclic triterpene skeleton from Achillea odorata L." Tetrahedron Letters. (wikipedia.org)
Quantitative2
Quantitative analysis of these triterpenes was performed for the purpose of crude drug quality control. (researchgate.net)
Nevertheless, these methods are only used for the qualitative or quantitative analysis of one type terpenoid (triterpenoid or sesquiterpenoid). (hindawi.com)
Alismatis1
Furthermore, this regulation of the ligand-gated ion channel activity by triterpenoids may be one of the pharmacological actions of Alismatis rhizoma. (ewha.ac.kr)
Active2
The main active ingredients of RA are classified into triterpenoids and sesquiterpenoids [ 9 , 10 ]. (hindawi.com)
Many components of Argan Oil are biologically active Triterpenoids . (arganoildirect.com)
Acid2
Maslinic Acid, a Natural Phytoalexin-Type Triterpene from Olives - A Promising Nutraceutical? (olivewellnessinstitute.org)
have reported anti-carcinogenic activity of both koetjapic acid and 3-oxo-olean-12-en-29-oic acid. (scialert.net)
Structures1
Triterpenes exist in a great variety of structures. (wikipedia.org)
Study2
In this study, a sensitive and reliable method based on an ultra-performance liquid chromatography (UPLC) couple with two ionisation modes, including electrospray ionisation (ESI) and atmospheric pressure chemical ionisation (APCI) tandem mass spectrometry (MS), namely, UPLC-ESI/APCI-MS/MS was developed and validated to simultaneously determine 8 triterpenoids (ESI mode) and 2 sesquiterpenoids (APCI mode) in RA. (hindawi.com)
The present study was designed to isolate and characterize triterpene components EAS and investigate the antihyperglycaemic effects alone or in combination with insulin in non-diabetic and streptozotocin (STZ)-induced diabetic rats. (endocrine-abstracts.org)